Antibody-directed delivery of anti-restenotic agents using inorganic nanoparticles (2009–2012)

Abstract:
Arteries that have been surgically treated to remove fatty lesions that block blood flow frequently become re-blocked (restenosed), and drugs to prevent this re-blockage often have bad side-effects. We propose to prevent these complications by target-delivering the drugs directly and only to the required site using a single injection at the time of surgery. This will limit systemic side-effects, treatment costs and incidence of reblocking and bleeding complications.
Grant type:
NHMRC Project Grant
Researchers:
  • Snr Group Leader/VC Snr Res Fellow
    Australian Institute for Bioengineering and Nanotechnology
    Affiliate Principal Research Fellow
    Centre for Horticultural Science
    Queensland Alliance for Agriculture and Food Innovation
Funded by:
National Health and Medical Research Council