The University of Queensland

Molecular mechanisms that help organise effective synaptic transmission. (2009–2012)

Abstract:

This study will test the idea that adhesion molecules alpha4- and beta2-laminin are needed for proper development and function of motor nerve - muscle connections. This study will provide insights into how such molecules control effective nerve-muscle communication, in both health and disease. We also believe that our results will provide the basic knowledge needed for identifying pharmacological targets that could improve such connections, and to promote reconnections between nerve and muscle.

Grant type:

NHMRC Project Grant

Researchers:

• 

  Associate Professor Peter Noakes

  Associate Professor
  

  School of Biomedical Sciences

  Faculty of Medicine

• 

  Professor David Craik

  UQ Laureate Fellow - GL
  

  Institute for Molecular Bioscience

Funded by:

National Health and Medical Research Council