Molecular mechanisms that help organise effective synaptic transmission. (2009–2012)

Abstract:
This study will test the idea that adhesion molecules alpha4- and beta2-laminin are needed for proper development and function of motor nerve - muscle connections. This study will provide insights into how such molecules control effective nerve-muscle communication, in both health and disease. We also believe that our results will provide the basic knowledge needed for identifying pharmacological targets that could improve such connections, and to promote reconnections between nerve and muscle.
Grant type:
NHMRC Project Grant
Researchers:
  • Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Director (Research Training)
    Research Strategy and Support (Medicine)
    Faculty of Medicine
    Affiliate Associate Professor
    Queensland Brain Institute
  • Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
  • ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council