A functional interaction between domains of the flavivirus NS5 protein presents a new target for antiviral therapy (2010–2012)

Abstract:
Mosquito-transmitted flaviviruses such as gengue, yellow fever, Japanese encephalitis and West Nile infect hundreds of millions of people and cause debilitating and fatal diseases. Developing anti-viral treatments against these diseases is a high priority. Our strategy is to develop small molecules that can bind to specific sites on viral proteins and prevent the virus from replicating and causing disease.
Grant type:
NHMRC Project Grant
Researchers:
  • Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
  • Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
  • NHMRC Snr Principal Research Fellow
    Institute for Molecular Bioscience
    Affiliated Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
  • Head of School
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Affiliated Professor
    Institute for Molecular Bioscience
    Affiliate Professor
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
National Health and Medical Research Council