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Enhancing erythropoietin therapy in ischaemia-reperfusion injury of heart and kidney (2010–2013)

Abstract:
Heart attacks and kidney disease from a lack of blood flow are common causes of morbidity and have poor treatment options. Erythropoietin (eps) is a useful new treatment, but there remain some caveats to its use in humans: eg. it may cause excessive scarring during repair. Use of epo with an anti-inflammatory drug may decrease scarring and provide benefit to long-term health. We plan to carefully define the biomolecular pathways of injury and repair, to better plan this therapy for human use.
Grant type:
NHMRC Project Grant
Researchers:

  • Professor David Johnson

    NHMRC Leadership Fellow
    Centre for Health Services Research
    Faculty of Medicine

  • Associate Professor David Vesey

    ATH - Associate Professor
    Princess Alexandra Hospital Southside Clinical Unit
    Faculty of Medicine

  • Professor Jeff Coombes

    Professor
    School of Human Movement and Nutrition Sciences
    Faculty of Health and Behavioural Sciences

  • Dr Gary Cowin

    NIF Facility Fellow
    Centre for Advanced Imaging
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
National Health and Medical Research Council