A novel role for SOX18 in regulating neo-lymphangiogenesis and tumour metastasis

Abstract:: Cancers are lethal mainly because they spread (metastasise) to other parts of the body via blood vessels and lymphatic ducts. Pilot studies suggest that suppressing the function of a gene, SOX18, reduces tumour metastasis. We now propose to confirm these findings and study this effect in detail, with the ultimate aim of developing new therapies able to complement existing anti-cancer treatments.
Grant type:: Cancer Council Queensland
Funded by:: Cancer Council Queensland