Skin Penetration of Nanoparticles Promoted by Particle Design, Formulation and Application Method (2012–2014)

Abstract:
This project aims to investigate human skin penetration and disposition of luminescent surface modified inorganic nanoparticles, varying in shape, surface property (charged, polarity) and size (1-20 nm) for a range of formulations and application methods. The project completion will indicate threshold properties at which nanoparticles penetrate through human skin as well as distribute into the reticuloendothelial and other vital body systems. Furthermore, understanding nanoparticle penetration through human skin in terms of its properties, potential formulations and application methods may help facilitate a better design and application methods for 'safe' nanomaterial products intended for cosmetic and therapeutic applications.
Grant type:
ARC Discovery Projects
Funded by:
Australian Research Council