Engineering Layered Double Hydroxide Nanoparticles toward an Efficient Targeted Clinical Delivery System (2013–2016)

Abstract:
Nanotechnology-based drug delivery systems will be a key component in the next generation of efficient drug formulations for the diagnosis and therapy of many fatal diseases, including cancers, cardiovascular and neuronal diseases. This project aims to develop such a system through engineering clay nanoparticles with inexpensive proteins and gaining fundamental insights into the interactions of engineered nanoparticles with plasma proteins. Completion of this project will produce potent delivery systems, facilitate the regulation of circulation half life and biodistribution of engineered nanoparticles, and lead to efficient treatment of these diseases in animal models, moving closer to clinical therapy.
Grant type:
ARC Future Fellowships
Researchers:
  • Snr Group Leader/VC Snr Res Fellow
    Australian Institute for Bioengineering and Nanotechnology
    Affiliate Principal Research Fellow
    Centre for Horticultural Science
    Queensland Alliance for Agriculture and Food Innovation
Funded by:
Australian Research Council