Dendritic information processing during sensory-motor behaviour (2013–2015)
The neocortex underlies all higher-order functions of the brain. However, it is largely unknown how individual neocortical neurons contribute to the neuronal computations that underlie behaviour. In vitro studies have shown that complex computational operations can be performed within the dendritic tree of neocortical neurons, but it is unknown if such processes are operational under behaviourally relevant conditions, and how they contribute to the function of the neocortex. We propose to explore the role of dendritic information processing in a class of neocortical pyramidal neuron embedded in a well-described neuronal circuit during the execution of a sensory-motor behaviour, and dissect how such computations are generated and modulated.