Development of a multicomponent delivery system for oligonucleotides (2013–2016)

Abstract:
This project introduces a novel delivery system for efficient in vitro delivery of nucleic acids to target cells. The proposed research aims to further improve current DNA/RNA-delivery systems, particularly cellular uptake, stability, targeting, and biological efficacy. The research aims to identify the optimal components for efficient delivery of a broad range of oligonucleotides. The approach proposed in this application is both novel and innovative, and will have a major contribution to our understanding of non-viral gene delivery mechanisms.
Grant type:
ARC Discovery Projects
Researchers:
  • Chair in Biological Chemistry
    School of Chemistry and Molecular Biosciences
    Faculty of Science
    Professor (Level E)
    School of Pharmacy
    Faculty of Health and Behavioural Sciences
    Affil Professorial Research Fellow
    Institute for Molecular Bioscience
  • Senior Lecturer
    School of Pharmacy
    Faculty of Health and Behavioural Sciences
Funded by:
Australian Research Council