Molecular regulation of metabolism and body composition by Ski vai crosstalk with nuclear hormone receptor signalling

Abstract:: Obesity is a common and burdensome health problem in the community which leads to diabetes and heart disease. A number of factors, including hormones play important roles in determining risk of obesity. This study proposes to investigate whether the Ski gene which is regulatory factor for many hormones affects metabolism in transgenic mouse models of altered Ski function. The proposed studies may identify Ski as a target for therapy for obesity and improvment in sketal muscle metabolism.
Grant type:: NHMRC Project Grant
Funded by:: National Health and Medical Research Council

The University of Queensland