Using toxins to understand the mechanisms of pain (2014–2018)

Abstract:
Toxins have evolved in plants, animals and microbes as part of defensive and/or prey capture strategies, and have proven to be invaluable research tools as well as providing leads for potential new therapies. The aim of this project is to use subtype-selective toxins to define the role of ion channels in pain using novel pathway-specific and disease-specific animal models of pain. The findings from this project will provide significant insight into the neuropharmacology of pain, will lead to the identification of novel molecular targets with analgesic potential and is expected to provide novel treatment approaches for pain.
Grant type:
ARC Future Fellowships
Researchers:
  • NHMRC Leadership Fellow - Group Lea
    School of Pharmacy
    Faculty of Health and Behavioural Sciences
    NHMRC Leadership Fellow - Group Lea
    Institute for Molecular Bioscience
Funded by:
Australian Research Council