Towards direct imaging of neuronal currents with MRI (2015–2017)
Current methods of detecting neuronal activity in the living human brain have limited spatial and temporal
resolution. Neuronal current MRI (nc-MRI) aims to overcome these limitations by imaging the effects on the
MRI signal of small transient magnetic fields associated with neuronal activity. Signal-to-noise ratio is at the
limits of detectability using current imaging systems and nc-MRI is yet to be convincingly demonstrated. This
project aims to develop novel nc-MRI methods that harness the oscillatory behavior of neuronal magnetic
fields. An integrated framework for simulating nc-MRI in the visual cortex will be developed. MRI experiments
with physical phantoms and human subjects will be used to test and optimise the novel methods.