Towards direct imaging of neuronal currents with MRI (2015–2017)

Abstract:
Current methods of detecting neuronal activity in the living human brain have limited spatial and temporal resolution. Neuronal current MRI (nc-MRI) aims to overcome these limitations by imaging the effects on the MRI signal of small transient magnetic fields associated with neuronal activity. Signal-to-noise ratio is at the limits of detectability using current imaging systems and nc-MRI is yet to be convincingly demonstrated. This project aims to develop novel nc-MRI methods that harness the oscillatory behavior of neuronal magnetic fields. An integrated framework for simulating nc-MRI in the visual cortex will be developed. MRI experiments with physical phantoms and human subjects will be used to test and optimise the novel methods.
Grant type:
ARC Discovery Projects
Researchers:
Funded by:
Australian Research Council