Defining the membrane protein cargo transported by Retromer (2016–2019)

Abstract:
Intracellular transport of biomolecules through the endosomal organelle is critical for normal cellular processes such as signaling and development. Endosomal transport occurs within membrane domains and membrane vesicular carriers formed by Retromer. This project aims to define the transmembrane proteins sorted by the distinct retromer complexes that form within the cell and the sorting signals essential for their correct trafficking and localisation.
Grant type:
ARC Discovery Projects
Researchers:
  • Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Associate Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science
Funded by:
Australian Research Council