Morphological development of the kidney: a paradigm for organogenesis (ARC Discovery Project administered by Monash University) (2016–2018)

Abstract:
This project Aims to investigate a remarkable mathematical pattern that we have discovered in the program of branching morphogenesis which dictates kidney development. By combining cutting edge genetic approaches, morphological analysis and mathematical modelling this project will explore how this pattern is established, how it dictates kidney development and whether it constitutes an ancient mechanism central to organ formation. In doing so the project will shed light on a fundamental developmental processes and it is anticipated that the findings will considerably impact our understanding of developmental disease and variation, and will be important for understanding the development of other organ systems.
Grant type:
Monash University
Funded by:
Monash University