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Breaching membrane barriers (2016–2018)

Abstract:
Cell membranes are barriers to macromolecules. The ability to cross these barriers and deliver biological macromolecules into cells represents a major achievement with endless opportunities to modulate pathways, to introduce biomarkers, therapeutics and research tools. This program proposes the development of novel molecular transporters to deliver macromolecules inside cells/microorganisms with academic/commercial relevance. This novel platform technology is based on stable cyclic peptides to deliver genes, proteins, probes or biomarkers into distinct cell types that can monitor/modulate specific pathways and be translated into new knowledge and into specific industrial applications.
Grant type:
ARC Future Fellowships
Funded by:
Australian Research Council