Lattice light sheet microscopy for imaging biology in real space and time (2017)
Lattice light sheet microscopy is a new modality for 4D imaging of live biological specimens ranging from
individual molecules to small organisms. The microscope enables unprecedented imaging of live specimens
without phototoxicity or photobleaching, enabling prolonged imaging of significant physiological or biophysical
events. The terabyte-scale image acquisition and handling requires dedicated computing infrastructure. This
proposal will establish a Lattice Light-Sheet Microscope (LLSM) Facility, based at The University of Queensland
and supported by researchers from UQ and four partnering institutions, to deliver state-of-the-art technology and innovative imaging capabilities to Queensland, including regional and interstate universities.
ARC Linkage Infrastructure, Equipment and Facilities