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Role of cellular lipids in flavivirus replication (2008–2010)

Abstract:
Mosquito bourne viruses like dengue fever & West Nile virus are responsible for many deaths each year, with little prophylatic treatments available. Project looks at look at how these viruses can replicate in cells and hide from our immune system. Cholesterol plays a major role in efficient virus replication and is crucial for us to fight infections. Project studies have indicated that West Nile virus can alter cholesterol metabolism and concentration within our bodies.
Grant type:
NHMRC Project Grant
Researchers:

  • Professor Alexander Khromykh

    Professor
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Professor Robert Parton

    ARC Laureate Fellow - Group Leader
    Institute for Molecular Bioscience
    Affiliate Professor
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council