The University of Queensland

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

Schlapbach, Luregn J., Ganesamoorthy, Devika, Wilson, Clare, Raman, Sainath, George, Shane, Snelling, Peter J., Phillips, Natalie, Irwin, Adam, Sharp, Natalie, Le Marsney, Renate, Chavan, Arjun, Hempenstall, Allison, Bialasiewicz, Seweryn, MacDonald, Anna D., Grimwood, Keith, Cling, Jessica C., McPherson, Stephen J., Blumenthal, Antje, Kaforou, Myrsini, Levin, Michael, Herberg, Jethro A., Gibbons, Kristen S., Coin, Lachlan J. M., EUCLIDS consortium and RAPIDS Study Group (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study. The Lancet Child and Adolescent Health. doi: 10.1016/S2352-4642(24)00017-8

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis

Chai, Gene G., Tu, Quyen, Cotta, Menino O., Bauer, Michelle J., Balch, Ross, Okafor, Charles, Comans, Tracy, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Ungerer, Jacobus P. J., McWhinney, Brett C., Farkas, Andras, Paterson, David L., Clark, Julia E., Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Forde, Brian M., Harris, Patrick N. A., Schlapbach, Luregn J., Coin, Lachlan, Roberts, Jason A. and Irwin, Adam D. (2024). Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis. Intensive Care Medicine, 1-9. doi: 10.1007/s00134-024-07353-3

Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases

Yeoh, Sophya, Estrada-Rivadeneyra, Diego, Jackson, Heather, Keren, Ilana, Galassini, Rachel, Cooray, Samantha, Shah, Priyen, Agyeman, Philipp, Basmaci, Romain, Carrol, Enitan, Emonts, Marieke, Fink, Colin, Kuijpers, Taco, Martinon-Torres, Federico, Mommert-Tripon, Marine, Paulus, Stephane, Pokorn, Marko, Rojo, Pablo, Romani, Lorenza, Schlapbach, Luregn, Schweintzger, Nina, Shen, Ching-Fen, Tsolia, Maria, Usuf, Effua, van der Flier, Michiel, Vermont, Clementien, von Both, Ulrich, Yeung, Shunmay, Zavadska, Dace ... DIAMONDS and UK KD Genetic Consortia (2024). Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases. Pediatric Infectious Disease Journal. doi: 10.1097/inf.0000000000004267

Resuscitation With Early Adrenaline Infusion for Children With Septic Shock: A Randomized Pilot Trial

Harley, Amanda, George, Shane, Phillips, Natalie, King, Megan, Long, Debbie, Keijzers, Gerben, Lister, Paula, Raman, Sainath, Bellomo, Rinaldo, Gibbons, Kristen, Schlapbach, Luregn J and Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform Study in the Emergency Department (RESPOND ED) Study Group (2024). Resuscitation With Early Adrenaline Infusion for Children With Septic Shock: A Randomized Pilot Trial. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 25 (2), 106-117. doi: 10.1097/PCC.0000000000003351

Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study

Schlapbach, Luregn J., Raman, Sainath, Buckley, David, George, Shane, King, Megan, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Erickson, Simon, Singh, Puneet, Festa, Marino, Gibbons, Kristen, Bellomo, Rinaldo and on behalf of Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group (2024). Resuscitation with vitamin C, hydrocortisone, and thiamin in children with septic shock: a multicenter randomized pilot study. Pediatric Critical Care Medicine, 25 (2), 159-170. doi: 10.1097/PCC.0000000000003346

Serum Levels of Vitamin C and Thiamin in Children With Suspected Sepsis: A Prospective Observational Cohort Study

McWhinney, Brett, Ungerer, Jacobus, LeMarsey, Renate, Phillips, Natalie, Raman, Sainath, Gibbons, Kristen, Schlapbach, Luregn J and Rapid Acute Paediatric Infection Diagnosis in Suspected Sepsis (RAPIDS) Study Investigators (2024). Serum Levels of Vitamin C and Thiamin in Children With Suspected Sepsis: A Prospective Observational Cohort Study. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 25 (2), 171-176. doi: 10.1097/PCC.0000000000003349

Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis

Harris, Patrick N. A., Bauer, Michelle J., Lüftinger, Lukas, Beisken, Stephan, Forde, Brian M., Balch, Ross, Cotta, Menino, Schlapbach, Luregn, Raman, Sainath, Shekar, Kiran, Kruger, Peter, Lipman, Jeff, Bialasiewicz, Seweryn, Coin, Lachlan, Roberts, Jason A., Paterson, David L. and Irwin, Adam D. (2024). Rapid nanopore sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis. Microbiology spectrum, 12 (2) e0306523, e0306523. doi: 10.1128/spectrum.03065-23

Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock

Sanchez-Pinto, L. Nelson, Bennett, Tellen D., Dewitt, Peter E., Russell, Seth, Rebull, Margaret N., Martin, Blake, Akech, Samuel, Albers, David J., Alpern, Elizabeth R., Balamuth, Fran, Bembea, Melania, Chisti, Mohammod Jobayer, Evans, Idris, Horvat, Christopher M., Jaramillo-Bustamante, Juan Camilo, Kissoon, Niranjan, Menon, Kusum, Scott, Halden F., Weiss, Scott L., Wiens, Matthew O., Zimmerman, Jerry J., Argent, Andrew C., Sorce, Lauren R., Schlapbach, Luregn J., Watson, R. Scott, Biban, Paolo, Carrol, Enitan, Chiotos, Kathleen, Flauzino De Oliveira, Claudio ... Wynn, James L. (2024). Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. doi: 10.1001/jama.2024.0196

International Consensus Criteria for Pediatric Sepsis and Septic Shock

Schlapbach, Luregn J., Watson, R. Scott, Sorce, Lauren R., Argent, Andrew C., Menon, Kusum, Hall, Mark W., Akech, Samuel, Albers, David J., Alpern, Elizabeth R., Balamuth, Fran, Bembea, Melania, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Dewitt, Peter E., Evans, Idris, Flauzino De Oliveira, Cláudio, Horvat, Christopher M., Inwald, David, Ishimine, Paul, Jaramillo-Bustamante, Juan Camilo, Levin, Michael, Lodha, Rakesh, Martin, Blake, Nadel, Simon, Nakagawa, Satoshi, Peters, Mark J., Randolph, Adrienne G. ... Bennett, Tellen D. (2024). International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. doi: 10.1001/jama.2024.0179

Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence

Brossier, David W, Goyer, Isabelle, Verbruggen, Sascha C A T, Jotterand Chaparro, Corinne, Rooze, Shancy, Marino, Luise V, Schlapbach, Luregn J, Tume, Lyvonne N and Valla, Frederic V (2024). Intravenous maintenance fluid therapy in acutely and critically ill children: state of the evidence. The Lancet Child & Adolescent Health, 8 (3), 236-244. doi: 10.1016/s2352-4642(23)00288-2

Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of England

van der Velden, Fabian J. S., Lim, Emma, Gills, Lily, Broadey, Jasmin, Hayes, Louise, Roberts, Eve, Courtney, Jack, Ball, Joanne, Herberg, Jethro, Galassini, Rachel, Emonts, Marieke, Levin, Michael, Cunnington, Aubrey, Kaforou, Myrsini, Wright, Victoria, Bellos, Evangelos, Broderick, Claire, Channon-Wells, Samuel, Cooray, Samantha, De, Tisham, D’Souza, Giselle, Elorrieta, Leire Estramiana, Estrada-Rivadeneyra, Diego, Habgood-Coote, Dominic, Hamilton, Shea, Jackson, Heather, Kavanagh, James, Marjaneh, Mahdi Moradi, Nichols, Samuel ... Ndure, Momodou (2023). Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of England. BMC Medical Ethics, 24 (1) 47. doi: 10.1186/s12910-023-00925-w

A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study

Jackson, Heather R., Zandstra, Judith, Menikou, Stephanie, Hamilton, Melissa Shea, McArdle, Andrew J., Fischer, Roman, Thorne, Adam M., Huang, Honglei, Tanck, Michael W., Jansen, Machiel H., De, Tisham, Agyeman, Philipp K A, Von Both, Ulrich, Carrol, Enitan D., Emonts, Marieke, Eleftheriou, Irini, Van der Flier, Michiel, Fink, Colin, Gloerich, Jolein, De Groot, Ronald, Moll, Henriette A., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J., Tsolia, Maria N., Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Kaforou, Myrsini (2023). A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. The Lancet. Digital health, 5 (11), e774-e785. doi: 10.1016/S2589-7500(23)00149-8

Avoid re-interpreting fluid bolus recommendations for low-income settings – Authors’ reply

Ranjit, Suchitra, Kissoon, Niranjan, Argent, Andrew, Inwald, David, Ventura, Andréa Maria Cordeiro, Jaborinsky, Roberto, Sankar, Jhuma, Carla de Souza, Daniela, Natraj, Rajeswari, Flauzino De Oliveira, Claudio, Samransamruajkit, Rujipat, Jayashree, Muralidharan and Schlapbach, Luregn J (2023). Avoid re-interpreting fluid bolus recommendations for low-income settings – Authors’ reply. The Lancet Child and Adolescent Health, 7 (11), e19-E19. doi: 10.1016/S2352-4642(23)00258-4

Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study

Wösten-van Asperen, Roelie M., la Roi-Teeuw, Hannah M., van Amstel, Rombout BE., Bos, Lieuwe DJ., Tissing, Wim JE., Jordan, Iolanda, Dohna-Schwake, Christian, Bottari, Gabriella, Pappachan, John, Crazzolara, Roman, Comoretto, Rosanna I., Mizia-Malarz, Agniezka, Moscatelli, Andrea, Sánchez-Martín, María, Willems, Jef, Rogerson, Colin M., Bennett, Tellen D., Luo, Yuan, Atreya, Mihir R., Faustino, E.Vincent S., Geva, Alon, Weiss, Scott L., Schlapbach, Luregn J., Sanchez-Pinto, L Nelson, Caballero, Marina, Margarit, Adriana, Campos, Roi, Möller, Paula, Serpe, Carmela ... Stroup, Emily (2023). Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective study. eClinicalMedicine, 65 102252, 102252. doi: 10.1016/j.eclinm.2023.102252

REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1)

Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460

Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study

Jimenez-Zambrano, Andrea, Ritger, Carly, Rebull, Margaret, Wiens, Matthew O., Kabajaasi, Olive, Jaramillo-Bustamante, Juan Camilo, Argent, Andrew C., Kissoon, Niranjan, Schlapbach, Luregn J., Sorce, Lauren R., Watson, R Scott, Dorsey Holliman, Brooke, Sanchez-Pinto, Lazaro N. and Bennett, Tellen D. (2023). Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study. BMJ open, 13 (10) e074458, 1-9. doi: 10.1136/bmjopen-2023-074458

Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe

Kolberg, Laura, Khanijau, Aakash, van der Velden, Fabian J S, Herberg, Jethro, De, Tisham, Galassini, Rachel, Cunnington, Aubrey J, Wright, Victoria, Shah, Priyen, Kaforou, Myrsini, Wilson, Clare, Kuijpers, Taco, Martinón-Torres, Federico, Rivero-Calle, Irene, Moll, Henriette, Vermont, Clementien, Pokorn, Marko, Kolnik, Mojca, Pollard, Andrew J, Agyeman, Philipp K A, Schlapbach, Luregn J, Tsolia, Maria N, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Schweintzger, Nina A, van der Flier, Michiel, de Groot, Ronald, Usuf, Effua ... The PERFORM Consortium (2023). Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe. Clinical Infectious Diseases. doi: 10.1093/cid/ciad615

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature

Habgood-Coote, Dominic, Wilson, Clare, Shimizu, Chisato, Barendregt, Anouk M., Philipsen, Ria, Galassini, Rachel, Calle, Irene Rivero, Workman, Lesley, Agyeman, Philipp K.A., Ferwerda, Gerben, Anderson, Suzanne T., van den Berg, J. Merlijn, Emonts, Marieke, Carrol, Enitan D., Fink, Colin G., de Groot, Ronald, Hibberd, Martin L., Kanegaye, John, Nicol, Mark P., Paulus, Stéphane, Pollard, Andrew J., Salas, Antonio, Secka, Fatou, Schlapbach, Luregn J., Tremoulet, Adriana H., Walther, Michael, Zenz, Werner, Van der Flier, Michiel, Zar, Heather J. ... Kaforou, Myrsini (2023). Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature. Med, 4 (9), 635-654.e5. doi: 10.1016/j.medj.2023.06.007

Adaptive clinical trials in pediatric critical care: a systematic review

Gilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273

Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study

Shah, Priyen, Voice, Marie, Calvo-Bado, Leonides, Rivero-Calle, Irene, Morris, Sophie, Nijman, Ruud, Broderick, Claire, De, Tisham, Eleftheriou, Irini, Galassini, Rachel, Khanijau, Aakash, Kolberg, Laura, Kolnik, Mojca, Rudzate, Aleksandra, Sagmeister, Manfred G., Schweintzger, Nina A., Secka, Fatou, Thakker, Clare, van der Velden, Fabian, Vermont, Clementien, Vincek, Katarina, Agyeman, Philipp K.A., Cunnington, Aubrey J., De Groot, Ronald, Emonts, Marieke, Fidler, Katy, Kuijpers, Taco W., Mommert-Tripon, Marine, Brengel-Pesce, Karen ... Geissler, J. (2023). Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. The Lancet Regional Health - Europe, 32 100682, 100682. doi: 10.1016/j.lanepe.2023.100682

Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol

Long, Debbie, Anderson, Vicki A., Crossley, Louise, Sood, Nikita Tuli, Charles, Karina R., MacDonald, Anna D., Bora, Samudragupta, Pestell, Carmela F., Murrell, Kathryn, Pride, Natalie A., Anderson, Peter J., Badawi, Nadia, Rose, Brian, Baillie, Heidi, Masterson, Kate, Chumbes Flores, Jenipher, Sherring, Claire, Raman, Sainath, Beca, John, Erickson, Simon, Festa, Marino, Anderson, Benjamin W., Venugopal, Prem, Yim, Deane, Andrews, David, Cheung, Michael, Brizard, Christian, Gentles, Thomas L., Iyengar, Ajay ... Gibbons, Kristen S. (2023). Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol. BMJ Open, 13 (8) e075429, e075429. doi: 10.1136/bmjopen-2023-075429

External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children

Martin, Alexander James, van der Velden, Fabian Johannes Stanislaus, von Both, Ulrich, Tsolia, Maria N, Zenz, Werner, Sagmeister, Manfred, Vermont, Clementien, de Vries, Gabriella, Kolberg, Laura, Lim, Emma, Pokorn, Marko, Zavadska, Dace, Martinón-Torres, Federico, Rivero-Calle, Irene, Hagedoorn, Nienke N, Usuf, Effua, Schlapbach, Luregn, Kuijpers, Taco W, Pollard, Andrew J, Yeung, Shunmay, Fink, Colin, Voice, Marie, Carrol, Enitan, Agyeman, Philipp K A, Khanijau, Aakash, Paulus, Stephane, De, Tisham, Herberg, Jethro Adam, Levin, Michael ... Emonts, Marieke (2023). External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children. Archives of Disease in Childhood, 109 (1), 58-66. doi: 10.1136/archdischild-2023-325869

Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens

Willems, Esther, Gloerich, Jolein, Suppers, Anouk, van der Flier, Michiel, van den Heuvel, Lambert P., van de Kar, Nicole, Philipsen, Ria H.L.A., van Dael, Maurice, Kaforou, Myrsini, Wright, Victoria J., Herberg, Jethro A., Torres, Federico Martinon, Levin, Michael, de Groot, Ronald, van Gool, Alain J., Lefeber, Dirk J., Wessels, Hans J.C.T., de Jonge, Marien I., Abdulla, Amina, Aebi, Christoph, van Aerde, Koen, Agbeko, Rachel, Agyeman, Philipp, D'alessandro, Umberto, Ali, Ladan, Alkema, Wynand, Allen, Karen, González, Fernando Álvez, Anderson, Suzanne ... on behalf of the PERFORM consortium (2023). Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens. iScience, 26 (8) 107257, 107257. doi: 10.1016/j.isci.2023.107257

Haemodynamic support for paediatric septic shock: a global perspective

Ranjit, Suchitra, Kissoon, Niranjan, Argent, Andrew, Inwald, David, Ventura, Andréa Maria Cordeiro, Jaborinsky, Roberto, Sankar, Jhuma, de Souza, Daniela Carla, Natraj, Rajeswari, De Oliveira, Claudio Flauzino, Samransamruajkit, Rujipat, Jayashree, Muralidharan and Schlapbach, Luregn J. (2023). Haemodynamic support for paediatric septic shock: a global perspective. The Lancet Child and Adolescent Health, 7 (8), 588-598. doi: 10.1016/s2352-4642(23)00103-7

Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis

Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) (2023). Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis. Intensive Care Medicine, 49 (9), 1151-1153. doi: 10.1007/s00134-023-07119-3

A qualitative investigation of paediatric intensive care staff attitudes towards the diagnosis of lower respiratory tract infection in the molecular diagnostics era

Clark, John A., Conway Morris, Andrew, Kanaris, Constantinos, Inwald, David, Butt, Warwick, Osowicki, Joshua, Schlapbach, Luregn J., Curran, Martin D., White, Deborah, Daubney, Esther, Agrawal, Shruti, Navapurkar, Vilas, Török, M. Estée, Baker, Stephen and Pathan, Nazima (2023). A qualitative investigation of paediatric intensive care staff attitudes towards the diagnosis of lower respiratory tract infection in the molecular diagnostics era. Intensive Care Medicine – Paediatric and Neonatal, 1 (1) 10, 10. doi: 10.1007/s44253-023-00008-z

Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study

Gilholm, Patricia, Gibbons, Kristen, Brüningk, Sarah, Klatt, Juliane, Vaithianathan, Rhema, Long, Debbie, Millar, Johnny, Tomaszewski, Wojtek, Schlapbach, Luregn J., Ganeshalingam, Anusha, Sherring, Claire, Erickson, Simon, Barr, Samantha, Raman, Sainath, Long, Debbie, Schlapbach, Luregn, Gibbons, Kristen, George, Shane, Singh, Puneet, Smith, Vicky, Butt, Warwick, Delzoppo, Carmel, Millar, Johnny, Gelbart, Ben, Oberender, Felix, Ganu, Subodh, Letton, Georgia, Festa, Marino, Harper, Gail and the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and ANZICS Paediatric Study Group (ANZICS PSG) (2023). Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study. Intensive Care Medicine, 49 (7), 785-795. doi: 10.1007/s00134-023-07137-1

Sensitivity of ICD coding for sepsis in children—a population-based study

Endrich, Olga, Triep, Karen, Schlapbach, Luregn J., Posfay-Barbe, Klara M., Heininger, Ulrich, Giannoni, Eric, Stocker, Martin, Niederer-Loher, Anita, Kahlert, Christian R., Natalucci, Giancarlo, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Berger, Christoph, Agyeman, Philipp K. A., Bär, Walter, Bernhard-Stirnemann, Sara, Hasters, Paul, Konetzny, Gabriel, Leone, Antonio and on behalf of the Swiss Pediatric Sepsis Study (2023). Sensitivity of ICD coding for sepsis in children—a population-based study. Intensive Care Medicine – Paediatric and Neonatal, 1 (1) 5, 5. doi: 10.1007/s44253-023-00006-1

Long‐term outcomes after paediatric sepsis (LOTUS)–A protocol for an Australian cohort study

Minogue, Jessicah, Schlapbach, Luregn J., Keogh, Samantha, Gibbons, Kristen and Long, Debbie (2023). Long‐term outcomes after paediatric sepsis (LOTUS)–A protocol for an Australian cohort study. Nursing in Critical Care, 29 (2), 438-443. doi: 10.1111/nicc.12938

Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature

Jackson, Heather R., Miglietta, Luca, Habgood-Coote, Dominic, D'Souza, Giselle, Shah, Priyen, Nichols, Samuel, Vito, Ortensia, Powell, Oliver, Davidson, Maisey Salina, Shimizu, Chisato, Agyeman, Philipp K. A., Beudeker, Coco R., Brengel-Pesce, Karen, Carrol, Enitan D., Carter, Michael J., De, Tisham, Eleftheriou, Irini, Emonts, Marieke, Epalza, Cristina, Georgiou, Pantelis, De Groot, Ronald, Fidler, Katy, Fink, Colin, van Keulen, Daniëlle, Kuijpers, Taco, Moll, Henriette, Papatheodorou, Irene, Paulus, Stephane, Pokorn, Marko ... EUCLIDS, PERFORM and DIAMONDS Consortia (2023). Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature. Journal of the Pediatric Infectious Diseases Society, 12 (6), 322-331. doi: 10.1093/jpids/piad035

Genomic investigations of unexplained acute hepatitis in children

Morfopoulou, Sofia, Buddle, Sarah, Torres Montaguth, Oscar Enrique, Atkinson, Laura, Guerra-Assunção, José Afonso, Moradi Marjaneh, Mahdi, Zennezini Chiozzi, Riccardo, Storey, Nathaniel, Campos, Luis, Hutchinson, J. Ciaran, Counsell, John R., Pollara, Gabriele, Roy, Sunando, Venturini, Cristina, Antinao Diaz, Juan F., Siam, Ala’a, Tappouni, Luke J., Asgarian, Zeinab, Ng, Joanne, Hanlon, Killian S., Lennon, Alexander, McArdle, Andrew, Czap, Agata, Rosenheim, Joshua, Andrade, Catarina, Anderson, Glenn, Lee, Jack C. D., Williams, Rachel, Williams, Charlotte A. ... Breuer, Judith (2023). Genomic investigations of unexplained acute hepatitis in children. Nature, 617 (7961), 564-573. doi: 10.1038/s41586-023-06003-w

Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection

Cook, Aislinn, Atkinson, Andrew, Kronenberg, Andreas, Agyeman, Philipp K. A., Schlapbach, Luregn J., Berger, Christoph, Bielicki, Julia Anna and Swiss Pediatric Sepsis Study Group (2023). Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection. Frontiers in Pediatrics, 11 1124165, 1-10. doi: 10.3389/fped.2023.1124165

Long-term outcomes after paediatric sepsis: A narrative review

Minogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn J. and Long, Debbie (2023). Long-term outcomes after paediatric sepsis: A narrative review. Australian Critical Care. doi: 10.1016/j.aucc.2023.04.002

Operationalizing appropriate sepsis definitions in children worldwide: considerations for the pediatric sepsis definition taskforce

Carrol, Enitan D., Ranjit, Suchitra, Menon, Kusum, Bennett, Tellen D., Sanchez-Pinto, L. Nelson, Zimmerman, Jerry J., Souza, Daniela C., Sorce, Lauren R., Randolph, Adrienne G., Ishimine, Paul, Flauzino de Oliveira, Claudio, Lodha, Rakesh, Harmon, Lori, Watson, R. Scott, Schlapbach, Luregn J., Kissoon, Niranjan, Argent, Andrew C. and on behalf of the Society of Critical Care Medicine’s Pediatric Sepsis Definition Taskforce (2023). Operationalizing appropriate sepsis definitions in children worldwide: considerations for the pediatric sepsis definition taskforce. Pediatric Critical Care Medicine, 24 (6), e263-e271. doi: 10.1097/pcc.0000000000003263

Impact of parental and healthcare professional concern on the diagnosis of pediatric sepsis: a diagnostic accuracy study

Sever, Zoe, Schlapbach, Luregn J., Gilholm, Patricia, Jessup, Melanie, Phillips, Natalie, George, Shane, Gibbons, Kristen and Harley, Amanda (2023). Impact of parental and healthcare professional concern on the diagnosis of pediatric sepsis: a diagnostic accuracy study. Frontiers in Pediatrics, 11 1140121, 1140121. doi: 10.3389/fped.2023.1140121

Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study

Channon-Wells, Samuel, Vito, Ortensia, McArdle, Andrew J., Seaby, Eleanor G., Patel, Harsita, Shah, Priyen, Pazukhina, Ekaterina, Wilson, Clare, Broderick, Claire, D'Souza, Giselle, Keren, Ilana, Nijman, Ruud G, Tremoulet, Adriana, Munblit, Daniel, Ulloa-Gutierrez, Rolando, Carter, Michael J, Ramnarayan, Padmanabhan, De, Tisham, Hoggart, Clive, Whittaker, Elizabeth, Herberg, Jethro A, Kaforou, Myrsini, Cunnington, Aubrey J, Blyuss, Oleg, Levin, Michael, Chouli, Mohamed, Hamadouche, Nacera, Ladj, Mohamed Samir, Agrimbau Vázquez, Jorge ... Kandawasvika, Gwendoline (2023). Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study. The Lancet Rheumatology, 5 (4), e184-e199. doi: 10.1016/S2665-9913(23)00029-2

Reporting of social determinants of health in pediatric sepsis studies

Menon, Kusum, Sorce, Lauren R., Argent, Andrew, Bennett, Tellen D., Carrol, Enitan D., Kissoon, Niranjan, Sanchez-Pinto, L. Nelson, Schlapbach, Luregn J., de Souza, Daniela C., Watson, R. Scott, Wynn, James L., Zimmerman, Jerry J., Ranjit, Suchitra and on behalf of the Pediatric Sepsis Definition Taskforce (2023). Reporting of social determinants of health in pediatric sepsis studies. Pediatric Critical Care Medicine, 24 (4), 301-310. doi: 10.1097/pcc.0000000000003184

Adeno-associated virus 2 infection in children with non-A-E hepatitis

Ho, Antonia, Orton, Richard, Tayler, Rachel, Asamaphan, Patawee, Herder, Vanessa, Davis, Chris, Tong, Lily, Smollett, Katherine, Manali, Maria, Allan, Jay, Rawlik, Konrad, McDonald, Sarah E., Vink, Elen, Pollock, Louisa, Gannon, Louise, Evans, Clair, McMenamin, Jim, Roy, Kirsty, Marsh, Kimberly, Divala, Titus, Holden, Matthew T. G., Lockhart, Michael, Yirrell, David, Currie, Sandra, O’Leary, Maureen, Henderson, David, Shepherd, Samantha J., Jackson, Celia, Gunson, Rory ... ISARIC4C investigators (2023). Adeno-associated virus 2 infection in children with non-A-E hepatitis. Nature, 617 (7961), 555-563. doi: 10.1038/s41586-023-05948-2

Nitric oxide on extracorporeal membrane oxygenation in neonates and children (NECTAR Trial): Protocol for a randomized controlled trial

Mattke, Adrian, Johnson, Kerry, Gibbons, Kristen, Long, Debbie, Robertson, Jeremy, Venugopal, Prem, Blumenthal, Antje, Schibler, Andreas and Schlapbach, Luregn (2023). Nitric oxide on extracorporeal membrane oxygenation in neonates and children (NECTAR Trial): Protocol for a randomized controlled trial. JMIR Research Protocols, 12 e43760, 1-10. doi: 10.2196/43760

Swiss Sepsis National Action Plan: a coordinated national action plan to stop sepsis-related preventable deaths and to improve the support of people affected by sepsis in Switzerland

Schlapbach, Luregn J., Zimmermann, Elisa A., Meylan, Sylvain, Stocker, Martin, Suter, Peter M., Jakob, Stephan M. and Swiss Sepsis National Action Plan Working Group (2023). Swiss Sepsis National Action Plan: a coordinated national action plan to stop sepsis-related preventable deaths and to improve the support of people affected by sepsis in Switzerland. Frontiers in Medicine, 10 1114546, 1-15. doi: 10.3389/fmed.2023.1114546

Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial

Welzel, Tatjana, Atkinson, Andrew, Schöbi, Nina, Andre, Maya C, Bailey, Douggl G N, Blanchard-Rohner, Geraldine, Buettcher, Michael, Grazioli, Serge, Koehler, Henrik, Perez, Marie-Helene, Trück, Johannes, Vanoni, Federica, Zimmermann, Petra, Sanchez, Carlos, Bielicki, Julia A, Schlapbach, Luregn J, Bieri, Andreas, Gysi, Spyridoula, Janz, Indra, Donner, Birgit, Hammer, Jürg, Heininger, Ulrich, Kohns Vasconcelos, Malte, Mettauer, Nicole, Meyer, Alexandra, Reppucci, Diana, Schlaeppi, Chloé, Trachsel, Daniel, Vaezipour, Nina ... Faust, Saul N (2023). Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. The Lancet Child & Adolescent Health, 7 (4), 238-248. doi: 10.1016/s2352-4642(23)00020-2

Erratum: Correction to: Group A streptococcal disease in paediatric inpatients: a European perspective (European journal of pediatrics (2023) 182 2 (697-706))

Boeddha, Navin P., Atkins, Lucy, de Groot, Ronald, Driessen, Gertjan, Hazelzet, Jan, Zenz, Werner, Carrol, Enitan D., Anderson, Suzanne T., Martinon-Torres, Federico, Agyeman, Philipp K A, Galassini, Rachel, Herberg, Jethro, Levin, Michael, Schlapbach, Luregn J. and Emonts, Marieke (2023). Erratum: Correction to: Group A streptococcal disease in paediatric inpatients: a European perspective (European journal of pediatrics (2023) 182 2 (697-706)). European journal of pediatrics, 182 (2), 707-707. doi: 10.1007/s00431-022-04787-z

Correction to: Febrile illness in high-risk children: a prospective, international observational study

van der Velden, Fabian J. S., de Vries, Gabriella, Martin, Alexander, Lim, Emma, von Both, Ulrich, Kolberg, Laura, Carrol, Enitan D., Khanijau, Aakash, Herberg, Jethro A., De, Tisham, Galassini, Rachel, Kuijpers, Taco W., Martinón-Torres, Federico, Rivero-Calle, Irene, Vermont, Clementien L., Hagedoorn, Nienke N., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J., Tsolia, Maria, Elefhteriou, Irini, Yeung, Shunmay, Zavadska, Dace, Fink, Colin, Voice, Marie, Zenz, Werner, Kohlmaier, Benno, Agyeman, Philipp K. A., Usuf, Effua ... PERFORM consortium (2023). Correction to: Febrile illness in high-risk children: a prospective, international observational study. European Journal of Pediatrics, 182 (2), 555-556. doi: 10.1007/s00431-022-04788-y

HPeV3 diversity, recombination and clinical impact across 7-years: an Australian story

Bialasiewicz, Seweryn, May, Meryta, Tozer, Sarah, Day, Rebecca, Bernard, Anne, Zaugg, Julian, Gartrell, Kyana, Alexandersen, Soren, Chamings, Anthony, Wang, Claire Y. T., Clark, Julia, Grimwood, Keith, Heney, Claire, Schlapbach, Luregn, Ware, Robert S., Speers, David, Andrews, Ross M. and Lambert, Stephen (2023). HPeV3 diversity, recombination and clinical impact across 7-years: an Australian story. The Journal of Infectious Diseases, 227 (2), 278-287. doi: 10.1093/infdis/jiac311

Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia

Gilholm, Patricia, Gibbons, Kristen, Lister, Paula, Harley, Amanda, Irwin, Adam, Raman, Sainath, Rice, Michael, Schlapbach, Luregn J. and Queensland Statewide Sepsis Collaborative (2023). Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia. BMJ Open, 13 (1) e061431, 1-25. doi: 10.1136/bmjopen-2022-061431

Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study

Cree, Michele, Haisz, Emma, Sumi, Chandra, Wallis, Steve, Schlapbach, Luregn, Roberts, Jason and Parker, Suzanne (2023). Are meropenem, piperacillin, tazobactam and vancomycin sequestered onto a paediatric extracorporeal membrane oxygenation circuit? An ex vivo study. Australian Critical Care, 36, S5-S6. doi: 10.1016/j.aucc.2023.07.023

Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control (Intensive Care Medicine, (2023), 10.1007/s00134-023-07127-3)

Giamarellos-Bourboulis, Evangelos J., Zinkernagel, Annelies S., De Robertis, Edoardo, Azoulay, Élie, De Luca, Daniele, Artigas, Antonio, Schlapbach, Luregn J, Daniels, Ron, Reinhart, Konrad, Baño, Jesús Rodríguez, Zacharowski, Kai and Cecconi, Maurizio (2023). Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control (Intensive Care Medicine, (2023), 10.1007/s00134-023-07127-3). Intensive Care Medicine, 49 (10), 1280-1280. doi: 10.1007/s00134-023-07197-3

Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study

Cree, Michele, Schlapbach, Luregn, Sumi, Chandra, Wallis, Steve, Roberts, Jason and Parker, Suzanne (2023). Does renal replacement therapy impact the clearance of meropenem, piperacillin, tazobactam and vancomycin in a critically ill child? An ex vivo study. Australian Critical Care, 36, S4-S5. doi: 10.1016/j.aucc.2023.07.020

Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study

Tan, Chantal D., Vermont, Clementien L., Zachariasse, Joany M., von Both, Ulrich, Eleftheriou, Irini, Emonts, Marieke, van der Flier, Michiel, Herberg, Jethro, Kohlmaier, Benno, Levin, Michael, Lim, Emma, Maconochie, Ian K., Martinon-Torres, Federico, Nijman, Ruud G., Pokorn, Marko, Rivero-Calle, Irene, Tsolia, Maria, Zenz, Werner, Zavadska, Dace, Moll, Henriëtte A., Carrol, Enitan D., Levin, Michael, Cunnington, Aubrey, De, Tisham, Herberg, Jethro, Kaforou, Myrsini, Wright, Victoria, Baumard, Lucas, Bellos, Evangelos ... On behalf of PERFORM consortium (Personalised Risk assessment in febrile children to optimize Real-life Management across the European Union) (2023). Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study. European Journal of Pediatrics, 182 (9), 3939-3947. doi: 10.1007/s00431-023-05056-3

Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control

Giamarellos-Bourboulis, Evangelos J., Zinkernagel, Annelies S., De Robertis, Edoardo, Azoulay, Élie, De Luca, Daniele, Artigas, Antonio, Schlapbach, Luregn J, Daniels, Ron, Reinhart, Konrad, Reinhart, Konrad, Baño, Jesús Rodríguez, Zacharowski, Kai and Cecconi, Maurizio (2023). Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control. Intensive Care Medicine, 49 (9), 1138-1142. doi: 10.1007/s00134-023-07127-3

Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial

Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912

Hemostasis proteins in invasive meningococcal and nonmeningococcal infections: a prospective multicenter study

Hagedoorn, Nienke N., Boeddha, Navin P., Kohlfuerst, Daniela S., Anderson, Suzanne, Carrol, Enitan D., Agapow, Paul, Van Der Flier, Michiel, Hazelzet, Jan, Herberg, Jethro, Kuijpers, Taco, Levin, Michael, Martinon-Torres, Federico, Van Rijswijk, Angelique, Schlapbach, Luregn J., Vermont, Clementien, Zenz, Werner, Dik, Willem A., Driessen, Gertjan and Emonts, Marieke (2022). Hemostasis proteins in invasive meningococcal and nonmeningococcal infections: a prospective multicenter study. Pediatric Critical Care Medicine, 23 (12), E543-E554. doi: 10.1097/PCC.0000000000003056

Organizational characteristics of European pediatric onco-critical care: An international cross-sectional survey

Nielsen, Jeppe S. A., Agbeko, Rachel, Bate, Jessica, Jordan, Iolanda, Dohna-Schwake, Christian, Potratz, Jenny, Moscatelli, Andrea, Bottari, Gabriella, Pappachan, John, Witt, Volker, Crazzolara, Roman, Amigoni, Angela, Mizia-Malarz, Agniezka, Sánchez Martín, Mariá, Willems, Jef, van den Heuvel-Eibrink, Marry M., Schlapbach, Luregn J., Wösten-van Asperen, Roelie M. and the POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric & Neonatal Intensive Care) (2022). Organizational characteristics of European pediatric onco-critical care: An international cross-sectional survey. Frontiers in Pediatrics, 10 1024273, 1-10. doi: 10.3389/fped.2022.1024273

Validation of an adapted Pediatric Sepsis Score in children admitted to PICU with invasive infection and sepsis: a retrospective analysis of a Dutch national cohort

Boeddha, Navin P., Schlapbach, Luregn J., Visser, Idse H., Jansen, Nicolaas J. G., Bollen, Casper, van Heerde, Marc, van der Heide, Douwe, Klein, Richard, Kneyber, Martin, Kuiper, Jan-Willem, Riedijk, Maaike, Verlaat, Carin and van Waardenburg, Dick (2022). Validation of an adapted Pediatric Sepsis Score in children admitted to PICU with invasive infection and sepsis: a retrospective analysis of a Dutch national cohort. Journal of Intensive Care, 10 (1) 26, 26. doi: 10.1186/s40560-022-00618-3

Group A streptococcal disease in paediatric inpatients: a European perspective

Boeddha, Navin P., Atkins, Lucy, de Groot, Ronald, Driessen, Gertjan, Hazelzet, Jan, Zenz, Werner, Carrol, Enitan D., Anderson, Suzanne T., Martinon-Torres, Federico, Agyeman, Philipp K. A., Galassini, Rachel, Herberg, Jethro, Levin, Michael, Schlapbach, Luregn J. and Emonts, Marieke (2022). Group A streptococcal disease in paediatric inpatients: a European perspective. European Journal of Pediatrics, 182 (2), 697-706. doi: 10.1007/s00431-022-04718-y

Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children-a systematic review and meta-analysis

Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clemence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kuhlwein, Eva, Lopez, Jorge, Lopez-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Minambres Rodriguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... Valla, Frederic V. (2022). Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children-a systematic review and meta-analysis. Intensive Care Medicine, 49 (1), 128-129. doi: 10.1007/s00134-022-06933-5

Reducing antibiotic exposure at the beginning of life

Schlapbach, Luregn J. and Carrol, Enitan D. (2022). Reducing antibiotic exposure at the beginning of life. JAMA Network Open, 5 (11) e2243705, 1-3. doi: 10.1001/jamanetworkopen.2022.43705

A Core Outcome Measurement Set for Pediatric Critical Care

Pinto, Neethi P., Maddux, Aline B., Dervan, Leslie A., Woodruff, Alan G., Jarvis, Jessica M., Nett, Sholeen, Killien, Elizabeth Y., Graham, Robert J., Choong, Karen, Luckett, Peter M., Heneghan, Julia A., Biagas, Katherine, Carlton, Erin F., Hartman, Mary E., Yagiela, Lauren, Michelson, Kelly N., Manning, Joseph C., Long, Debbie A., Lee, Jan Hau, Slomine, Beth S., Beers, Sue R., Hall, Trevor, Morrow, Brenda M., Meert, Kathleen, Arias Lopez, Maria del Pilar, Knoester, Hennie, Houtrow, Amy, Olson, Lenora, Steele, Lisa ... Zuppa, Athena (2022). A Core Outcome Measurement Set for Pediatric Critical Care. Pediatric Critical Care Medicine, 23 (11), 893-907. doi: 10.1097/PCC.0000000000003055

A core outcome measurement set for pediatric critical care

Pinto, Neethi P., Maddux, Aline B., Dervan, Leslie A., Woodruff, Alan G., Jarvis, Jessica M., Nett, Sholeen, Killien, Elizabeth Y., Graham, Robert J., Choong, Karen, Luckett, Peter M., Heneghan, Julia A., Biagas, Katherine, Carlton, Erin F., Hartman, Mary E., Yagiela, Lauren, Michelson, Kelly N., Manning, Joseph C., Long, Debbie A., Lee, Jan Hau, Slomine, Beth S., Beers, Sue R., Hall, Trevor, Morrow, Brenda M., Meert, Kathleen, Arias Lopez, Maria Del Pilar, Knoester, Hennie, Houtrow, Amy, Olson, Lenora, Steele, Lisa ... Zuppa, Athena (2022). A core outcome measurement set for pediatric critical care. Pediatric Critical Care Medicine, 23 (11), 893-907. doi: 10.1097/PCC.0000000000003055

OP075 [Critical Care Rehabilitation » Developmental care]: EDUCATIONAL OUTCOMES OF CHILDHOOD SURVIVORS OF CRITICAL ILLNESS – A POPULATION-BASED LINKAGE STUDY

Schlapbach, L. J., Tomaszewski, W., Ablaza, C., Straney, L., Taylor, C. and Millar, J. (2022). OP075 [Critical Care Rehabilitation » Developmental care]: EDUCATIONAL OUTCOMES OF CHILDHOOD SURVIVORS OF CRITICAL ILLNESS – A POPULATION-BASED LINKAGE STUDY. Pediatric Critical Care Medicine, 23 (Supplement 1 11S). doi: 10.1097/01.pcc.0000899980.76828.0e

Pragmatic trials for critical illness in neonates and children

Schlapbach, Luregn J and Peters, Mark J (2022). Pragmatic trials for critical illness in neonates and children. The Lancet Child & Adolescent Health, 7 (2), 78-79. doi: 10.1016/s2352-4642(22)00345-5

ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis

Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) (2022). ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis. Intensive Care Medicine, 48 (12), 1691-1708. doi: 10.1007/s00134-022-06882-z

Febrile illness in high-risk children: a prospective, international observational study

van der Velden, Fabian J. S., de Vries, Gabriella, Martin, Alexander, Lim, Emma, von Both, Ulrich, Kolberg, Laura, Carrol, Enitan D., Khanijau, Aakash, Herberg, Jethro A., De, Tisham, Galassini, Rachel, Kuijpers, Taco W., Martinón-Torres, Federico, Rivero-Calle, Irene, Vermont, Clementien L., Hagedoorn, Nienke N., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J., Tsolia, Maria, Elefhteriou, Irini, Yeung, Shunmay, Zavadska, Dace, Fink, Colin, Voice, Marie, Zenz, Werner, Kohlmaier, Benno, Agyeman, Philipp K. A., Usuf, Effua ... Emonts, Marieke (2022). Febrile illness in high-risk children: a prospective, international observational study. European Journal of Pediatrics, 182 (2), 543-554. doi: 10.1007/s00431-022-04642-1

Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study

Tan, Chantal D., van der Walle, Eline E. P. L., Vermont, Clementien L., von Both, Ulrich, Carrol, Enitan D., Eleftheriou, Irini, Emonts, Marieke, van der Flier, Michiel, de Groot, Ronald, Herberg, Jethro, Kohlmaier, Benno, Levin, Michael, Lim, Emma, Maconochie, Ian K., Martinon-Torres, Federico, Nijman, Ruud G., Pokorn, Marko, Rivero-Calle, Irene, Tsolia, Maria, Yeung, Shunmay, Zenz, Werner, Zavadska, Dace, Moll, Henriëtte A., Levin, Michael, Cunnington, Aubrey, De, Tisham, Herberg, Jethro, Kaforou, Myrsini, Wright, Victoria ... Geissler, J. (2022). Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study. European Journal of Pediatrics, 181 (12), 4199-4209. doi: 10.1007/s00431-022-04606-5

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations

Kumar, Vikrant, Pouw, Richard B., Autio, Matias I., Sagmeister, Manfred G., Phua, Zai Yang, Borghini, Lisa, Wright, Victoria J., Hoggart, Clive, Pan, Bangfen, Tan, Antson Kiat Yee, Binder, Alexander, Brouwer, Mieke C., Pinnock, Ellie, De Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van Der Flier, Michiel, Reiter, Karl, Nöthen, Markus M., Hoffmann, Per, Schlapbach, Luregn J., Bellos, Evangelos, Anderson, Suzanne, Secka, Fatou, Martinón-Torres, Federico, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J. ... Davila, Sonia (2022). Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations. American Journal of Human Genetics, 109 (9), 1680-1691. doi: 10.1016/j.ajhg.2022.08.001

Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y)

Morice, Claire, Alsohime, Fahad, Mayberry, Huw, Tume, Lyvonne N., Brossier, David, Valla, Frederic V., Didier, Capucine, Moullet, Clémence, Jotterand Chaparro, Corinne, Kühlwein, Eva, Chiusolo, Fabrizio, Porcheret, Florence, Mehmeti, Fortesa, Tekguc, Hakan, Ilia, Stavroula, Goyer, Isabelle, Lopez-Herce, Jesus, Pappachan, John, Lopez, Jorge, Tziouvas, Konstantinos, Costa, Leonardo, Boto, Leonor Reis, Marino, Luise, Schlapbach, Luregn J, Mierzewska-Schmidt, Magdalena, Minambres, Maria, Kneyber, Martin, Fae, Monica, Joram, Nyandat ... Beldjilali, Sophie (2022). Correction to: Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey (European Journal of Pediatrics, (2022), 181, 8, (3163-3172), 10.1007/s00431-022-04467-y). European Journal of Pediatrics, 181 (8), 3173-3173. doi: 10.1007/s00431-022-04513-9

Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices

Clos, Maité, Schlapbach, Luregn J., Arata-Bardet, Julie, Javouhey, Etienne and Mortamet, Guillaume (2022). Antimicrobial stewardship programs in European pediatric intensive care units: an international survey of practices. European Journal of Pediatrics, 181 (7), 2873-2877. doi: 10.1007/s00431-022-04481-0

Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol

Long, Debbie, Gibbons, Kristen, Dow, Belinda, Best, James, Webb, Kerri-Lyn, Liley, Helen G., Stocker, Christian, Thoms, Debra, Schlapbach, Luregn J., Wharton, Carolyn, Lister, Paula, Matuschka, Lori, Castillo, Maria Isabel, Tyack, Zephanie and Bora, Samudragupta (2022). Effectiveness–implementation hybrid-2 randomised trial of a collaborative Shared Care Model for Detecting Neurodevelopmental Impairments after Critical Illness in Young Children (DAISY): pilot study protocol. BMJ Open, 12 (7) e060714, 1-11. doi: 10.1136/bmjopen-2021-060714

Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients

Fan, Bowen, Klatt, Juliane, Moor, Michael M., Daniels, Latasha A., Sanchez-Pinto, Lazaro N., Agyeman, Philipp K. A., Schlapbach, Luregn J. and Borgwardt, Karsten M. (2022). Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients. Bioinformatics, 38 (Supplement 1), I101-I108. doi: 10.1093/bioinformatics/btac229

Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept

Schlapbach, Luregn J. and Kissoon, Niranjan (2022). Resuscitating children with sepsis and impaired perfusion with maintenance fluids: an evolving concept. Pediatric Critical Care Medicine, 23 (7), 563-565. doi: 10.1097/PCC.0000000000002990

Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial

Schlapbach, Luregn J., Gibbons, Kristen S., Horton, Stephen B., Johnson, Kerry, Long, Debbie A., Buckley, David H. F., Erickson, Simon, Festa, Marino, D'Udekem, Yves, Alphonso, Nelson, Winlaw, David S., Delzoppo, Carmel, Van Loon, Kim, Jones, Mark, Young, Paul J., Butt, Warwick and Schibler, Andreas (2022). Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: the NITRIC Randomized Clinical Trial. JAMA: Journal of the American Medical Association, 328 (1), 38-47. doi: 10.1001/jama.2022.9376

Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia

Blythe, Robin, Lister, Paula, Seaton, Robert, Harley, Amanda, Schlapbach, Luregn J., McPhail, Steven, Venkatesh, Bala, Irwin, Adam, Raman, Sainath, Schlapbach, Luregn, Harley, Amanda, Irwin, Adam, Graham, Nicolette, Thomson, Fiona, Owen, Kieran, Garrish, Kirsten, Sampson, Emma, Long, Debbie, George, Shane, Grimwood, Keith, Bell, Christa, Semple, Bethany, Adams, Claire, Brown, Josea, Maloney, Louise, Lister, Paula, Schofield, Scott, Thomas, Clare, Dejong, Liam ... the Queensland State-wide Sepsis Collaborative (2022). Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia. Scientific Reports, 12 (1) 10113, 10113. doi: 10.1038/s41598-022-14226-6

The current and future state of pediatric sepsis definitions: an international survey

Morin, Luc, Hall, Mark, de Souza, Daniela, Guoping, Lu, Jabornisky, Roberto, Shime, Nobuaki, Ranjit, Suchitra, Gilholm, Patricia, Nakagawa, Satoshi, Zimmerman, Jerry J., Sorce, Lauren R., Argent, Andrew, Kissoon, Niranjan, Tissières, Pierre, Watson, R. Scott and Schlapbach, Luregn J (2022). The current and future state of pediatric sepsis definitions: an international survey. Pediatrics, 149 (6) ARTN e2021052565. doi: 10.1542/peds.2021-052565

Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial

Welzel, Tatjana, Schöbi, Nina, André, Maya C., Bailey, Douggl G. N., Blanchard-Rohner, Geraldine, Buettcher, Michael, Grazioli, Serge, Koehler, Henrik, Perez, Marie-Helene, Trück, Johannes, Vanoni, Federica, Zimmermann, Petra, Atkinson, Andrew, Sanchez, Carlos, Whittaker, Elizabeth, Faust, Saul N., Bielicki, Julia A. and Schlapbach, Luregn J. (2022). Multicenter randomized trial of methylprednisolone vs. intravenous immunoglobulins to treat the pediatric inflammatory multisystem syndrome—temporally associated with SARS-CoV-2 (PIMS-TS): protocol of the Swissped RECOVERY Trial. Frontiers in Pediatrics, 10 905046, 1-12. doi: 10.3389/fped.2022.905046

Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study

Equey, Lucile, Agyeman, Philipp K. A., Veraguth, Rosemarie, Rezzi, Serge, Schlapbach, Luregn J. and Giannoni, Eric (2022). Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study. Pediatric Critical Care Medicine, 23 (5), 390-394. doi: 10.1097/PCC.0000000000002911

Time to tackle early-onset sepsis in low-income and middle-income countries

Schlapbach, Luregn J, Hagmann, Cornelia and Giannoni, Eric (2022). Time to tackle early-onset sepsis in low-income and middle-income countries. The Lancet Global Health, 10 (5), e592-e593. doi: 10.1016/S2214-109X(22)00086-9

Endothelial damage in sepsis: the importance of systems biology

Fernández-Sarmiento, Jaime, Schlapbach, Luregn J., Acevedo, Lorena, Santana, Carolina Ramírez, Acosta, Yeny, Diana, Ampudia, Monsalve, M. and Carcillo, Joseph A. (2022). Endothelial damage in sepsis: the importance of systems biology. Frontiers in Pediatrics, 10 828968, 828968. doi: 10.3389/fped.2022.828968

Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis

Stocker, Martin, Daunhawer, Imant, Van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., Van Den Tooren-De Groot, Rita K., Wieringa, Jantien W., Janota, Jan, Van Der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., De Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., De Mol, Amerik C., Hoffmann-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., Van Gijsel, Juliette, Plötz, Frans B., Wellmann, Sven, Achten, Niek B., Lehnick, Dirk, Van Rossum, Annemarie M. C. and Vogt, Julia E. (2022). Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis. Pediatric Infectious Disease Journal, 41 (3), 248-254. doi: 10.1097/INF.0000000000003344

Educational outcomes of childhood survivors of critical illness—A population-based linkage study

Tomaszewski, Wojtek, Ablaza, Christine, Straney, Lahn, Taylor, Catherine, Millar, Johnny and Schlapbach, Luregn (2022). Educational outcomes of childhood survivors of critical illness—A population-based linkage study. Critical Care Medicine, Publish Ahead of Print (6), 901-912. doi: 10.1097/CCM.0000000000005461

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

McBride, Craig Antony, Rahiman, Sarfaraz, Schlapbach, Luregn J., Schults, Jessica A., Kleidon, Tricia M., Kennedy, Melanie, Paterson, Rebecca S., Byrnes, Joshua, Ware, Robert S. and Ullman, Amanda Judith (2022). Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial. BMJ Open, 12 (2) e047765, e047765. doi: 10.1136/bmjopen-2020-047765

Understanding detrimental host response to infection: the promise of transcriptomics

Schlapbach, Luregn J and Coin, Lachlan (2022). Understanding detrimental host response to infection: the promise of transcriptomics. Pediatric critical care medicine, 23 (2), 133-135. doi: 10.1097/PCC.0000000000002870

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Evans, Idris V. R., Inwald, David P., Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Nadel, Simon, Oliveira, Cláudio Flauzino, Peters, Mark, Sadeghirad, Benham, Scott, Halden F., De Souza, Daniela C., Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Zimmerman, Jerry J. and Sorce, Lauren R. (2022). Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce. Critical Care Medicine, 50 (1), 21-36. doi: 10.1097/CCM.0000000000005294

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

Slooff, Valerie, Hoogendoorn, Rianne, Nielsen, Jeppe Sylvest Angaard, Pappachan, John, Amigoni, Angela, Caramelli, Fabio, Aziz, Omer, Wildschut, Enno, Verbruggen, Sascha, Crazzolara, Roman, Dohna-Schwake, Christian, Potratz, Jenny, Willems, Jef, Llevadias, Judit, Moscatelli, Andrea, Montaguti, Alessia, Bottari, Gabriella, Di Nardo, Matteo, Schlapbach, Luregn, Wösten-van Asperen, Roelie and POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric Neonatal Intensive Care) (2022). Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies. Annals of Intensive Care, 12 (1) 8, 1-11. doi: 10.1186/s13613-022-00983-0

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M. ... Molloy, Eleanor J. (2022). Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials. Pediatric Research, 91 (4), 735-742. doi: 10.1038/s41390-021-01883-y

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary

Bembea, Melania M., Agus, Michael, Akcan-Arikan, Ayse, Alexander, Peta, Basu, Rajit, Bennett, Tellen D., Bohn, Desmond, Brandão, Leonardo R., Brown, Ann-Marie, Carcillo, Joseph A., Checchia, Paul, Cholette, Jill, Cheifetz, Ira M., Cornell, Timothy, Doctor, Allan, Eckerle, Michelle, Erickson, Simon, Farris, Reid W D, Faustino, E Vincent S, Fitzgerald, Julie C., Fuhrman, Dana Y., Giuliano, John S., Guilliams, Kristin, Gaies, Michael, Gorga, Stephen M., Hall, Mark, Hanson, Sheila J., Hartman, Mary, Hassinger, Amanda B. ... Zimmerman, Jerry J. (2022). Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary. Pediatrics, 149 (1), S1-S12. doi: 10.1542/peds.2021-052888B

Refining the pediatric multiple organ dysfunction syndrome

Weiss, Scott L., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Schlapbach, Luregn J., Tissieres, Pierre, Wynn, James L. and Lacroix, Jacques (2022). Refining the pediatric multiple organ dysfunction syndrome. Pediatrics, 149 (1) e2021052888C, S13-S22. doi: 10.1542/peds.2021-052888C

Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference

Schlapbach, Luregn J., Weiss, Scott L., Bembea, Melania M., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Tissieres, Pierre, Wynn, James L., Zimmerman, Jerry and Lacroix, Jacques (2022). Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference. Pediatrics, 149 (Supplement 1) e2021052888D, S23-S31. doi: 10.1542/peds.2021-052888D

Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?

Schlapbach, Luregn J., van Rossum, Annemarie and Carrol, Enitan D. (2021). Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?. The Lancet Infectious Diseases, 21 (12), 1617-1618. doi: 10.1016/S1473-3099(21)00199-7

Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

Geraerds, A. J.L.M., van Herk, Wendy, Stocker, Martin, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien, Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., van Gijsel, Juliette, Visser, Eline G., van Rossum, Annemarie M. C. and Polinder, Suzanne (2021). Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates. Critical Care, 25 (1) 367, 367. doi: 10.1186/s13054-021-03789-x

Neonatal sepsis definitions from randomised clinical trials

Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M. ... Molloy, Eleanor J. (2021). Neonatal sepsis definitions from randomised clinical trials. Pediatric Research, 93 (5), 1-8. doi: 10.1038/s41390-021-01749-3

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis

Boeddha, Navin P., Driessen, Gertjan J., Hagedoorn, Nienke N., Kohlfuerst, Daniela S., Hoggart, Clive J., van Rijswijk, Angelique L., Ekinci, Ebru, Priem, Debby, Schlapbach, Luregn J., Herberg, Jethro A., de Groot, Ronald, Anderson, Suzanne T., Fink, Colin G., Carrol, Enitan D., van der Flier, Michiel, Martinón-Torres, Federico, Levin, Michael, Leebeek, Frank W., Zenz, Werner, de Maat, Moniek P. M., Hazelzet, Jan A., Emonts, Marieke and Dik, Willem A. (2021). Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis. Critical Care Explorations, 3 (11) e0569, e0569. doi: 10.1097/CCE.0000000000000569

Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study

Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573

Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study

Harley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2

Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review

Simpson, Adam, Long, Deborah, Fleischmann-Struzek, Carolin, Minogue, Jessicah, Venkatesh, Balasubramanian, Hammond, Naomi E., Tian, David H. and Schlapbach, Luregn J. (2021). Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review. Frontiers in Pediatrics, 9 734205, 734205. doi: 10.3389/fped.2021.734205

Metabolic resuscitation in pediatric sepsis: a narrative review

Schlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1

A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?

Schlapbach, Luregn J., Reinhart, Konrad, Kissoon, Niranjan and On behalf of the Pediatric Sepsis Data CoLaboratory (Sepsis CoLab) and the Global Sepsis Alliance (GSA) (2021). A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?. American Journal of Physiology-Lung Cellular and Molecular Physiology, 321 (3), L608-L613. doi: 10.1152/ajplung.00331.2021

Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational study

Sever, Zoe, Schlapbach, Luregn J, Jessup, Melanie, George, Shane and Harley, Amanda (2021). Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational study. BMJ Open, 11 (9) e045910, e045910. doi: 10.1136/bmjopen-2020-045910

A novel framework for phenotyping children with suspected or confirmed infection for future biomarker studies

Nijman, Ruud G., Oostenbrink, Rianne, Moll, Henriette A., Casals-Pascual, Climent, von Both, Ulrich, Cunnington, Aubrey, De, Tisham, Eleftheriou, Irini, Emonts, Marieke, Fink, Colin, van der Flier, Michiel, de Groot, Ronald, Kaforou, Myrsini, Kohlmaier, Benno, Kuijpers, Taco W., Lim, Emma, Maconochie, Ian K., Paulus, Stephane, Martinon-Torres, Federico, Pokorn, Marko, Romaine, Sam T., Calle, Irene Rivero, Schlapbach, Luregn J., Smit, Frank J., Tsolia, Maria, Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Carrol, Enitan D. (2021). A novel framework for phenotyping children with suspected or confirmed infection for future biomarker studies. Frontiers in Pediatrics, 9 688272, 1-18. doi: 10.3389/fped.2021.688272

Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations

Tu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578

0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial

Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5

Treatment of Multisystem Inflammatory Syndrome in Children

McArdle, Andrew J., Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G., Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H., Munblit, Daniel, Ulloa-Gutierrez, Rolando, Carter, Michael J., De, Tisham, Hoggart, Clive, Whittaker, Elizabeth, Herberg, Jethro A., Kaforou, Myrsini, Cunnington, Aubrey J., Levin, Michael, Vazquez, Jorge Agrimbau, Carmona, Rodrigo, Perez, Laura, Rubinos, Mayra, Veliz, Natalia, Yori, Silvana, Haerynck, Filomeen, Hoste, Levi, Leal, Izabel Alves, Da Silva, Andre Ricardo Araujo ... Kandawasvika, Gwendoline (2021). Treatment of Multisystem Inflammatory Syndrome in Children. New England Journal of Medicine, 385 (1) NEJMoa2102968, 11-22. doi: 10.1056/NEJMoa2102968

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group

Raman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6

Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan

Harley, Amanda, George, Shane, King, Megan, Phillips, Natalie, Keijzers, Gerben, Long, Debbie, Gibbons, Kristen, Bellomo, Rinaldo and Schlapbach, Luregn J. (2021). Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan. Frontiers in Pediatrics, 9 663028, 663028. doi: 10.3389/fped.2021.663028

Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in Switzerland

Schlapbach, Luregn J., Andre, Maya C., Grazioli, Serge, Schöbi, Nina, Ritz, Nicole, Aebi, Christoph, Agyeman, Philipp, Albisetti, Manuela, Bailey, Douggl G. N., Berger, Christoph, Blanchard-Rohner, Géraldine, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G., Marston, Mark, Meyer Sauteur, Patrick M., Pachlopnik Schmid, Jana, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes, Woerner, Andreas, Wütz, Daniela, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth and Rimensberger, Peter C. (2021). Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in Switzerland. Frontiers in Pediatrics, 9 667507, 667507. doi: 10.3389/fped.2021.667507

Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study

Romaine, Sam T., Sefton, Gerri, Lim, Emma, Nijman, Ruud G., Bernatoniene, Jolanta, Clark, Simon, Schlapbach, Luregn J., Pallmann, Philip and Carrol, Enitan D. (2021). Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open, 11 (5) e044091, e044091. doi: 10.1136/bmjopen-2020-044091

Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan

Schlapbach, Luregn J., Gibbons, Kristen, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Buckley, David, Erickson, Simon, Festa, Marino, George, Shane, King, Megan, Singh, Puneet, Raman, Sainath, Bellomo, Rinaldo and The RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2021). Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan. Frontiers in Pediatrics, 9 663435, 1-10. doi: 10.3389/fped.2021.663435

Challenges in the recognition and management of paediatric sepsis — the journey

Harley, Amanda, Schlapbach, Luregn J., Johnston, Amy N. B. and Massey, Debbie (2021). Challenges in the recognition and management of paediatric sepsis — the journey. Australasian Emergency Care, 25 (1), 23-29. doi: 10.1016/j.auec.2021.03.006

An assessment of knowledge and education about sepsis among medical students: a multi-university survey

Datta, Rachit, Di Tanna, Gian Luca, Youssef, Marina, Harley, Amanda, Schlapbach, Luregn J., Nunnink, Leo and Venkatesh, Balasubramanian (2021). An assessment of knowledge and education about sepsis among medical students: a multi-university survey. Critical Care and Resuscitation, 23 (1), 117-118. doi: 10.51893/2021.1.rl2

Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial

Gibbons, Kristen S., Schlapbach, Luregn J., Horton, Stephen B., Long, Debbie A., Beca, John, Erickson, Simon, Festa, Marino, d'Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, Brenda, Fooken, Jonas, Blumenthal, Antje, Young, Paul J., Butt, Warwick and Schibler, Andreas (2021). Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Critical Care and Resuscitation, 23 (1), 47-58.

Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial

Gibbons, Kristen S., Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia, Schlapbach, Luregn J., Johnson, Kerry, Horton, Stephen B., Long, Debbie A., Beca, John, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David, Delzoppo, Carmel, van Loon, Kim, Gannon, Brenda, Fooken, Jonas, Blumenthal, Antje, Young, Paul J., Butt, Warwick, Schibler, Andreas, Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia, Paediatric Intensive Care Unit, Queensland Children’s Hospital, Children’s Health Queensland, Brisbane, Queensland, Australia, Department of Intensive Care Medicine and Neonatology, and Children’s Research Center, University Children’s Hospital Zurich, University of Zurich, Zurich, Switzerland, Cardiac Surgical Unit, Royal Children’s Hospital, Melbourne, Victoria, Australia, Faculty of Medicine, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia, Murdoch Children’s Research Institute, Melbourne, Victoria, Australia, Paediatric Critical Care Research Group, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia, Paediatric Intensive Care Unit, Queensland Children’s Hospital, Children’s Health Queensland, Brisbane, Queensland, Australia, Paediatric Intensive Care Unit, Starship Children’s Hospital, Auckland, New Zealand ... Paediatric Intensive Care Unit, Queensland Children’s Hospital, Children’s Health Queensland, Brisbane, Queensland, Australia (2021). Statistical analysis plan for the NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC) trial. Critical Care and Resuscitation, 23 (1), 47-58. doi: 10.51893/2021.1.oa4

The challenge of infrequency

Long, Elliot, Schlapbach, Luregn J. and Babl, Franz E. (2021). The challenge of infrequency. Acta Paediatrica, 110 (3), 1075-1075. doi: 10.1111/apa.15647

Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review

Yanase, Fumitaka, Raman, Sainath, Naorungroj, Thummaporn, McCarthy, Avril, Cree, Michele, Schlapbach, Luregn J and Bellomo, Rinaldo (2021). Efficacy and safety of parenteral high-dose vitamin C therapy in pediatric patients: a scoping review. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 22 (6), 561-571. doi: 10.1097/PCC.0000000000002686

Epidemiology of sepsis among children and neonates in Germany: Results from an observational study based on nationwide diagnosis-related groups data between 2010 and 2016∗

Born, Sebastian, Dame, Christof, Matthäus-Krämer, Claudia, Schlapbach, Luregn J., Reichert, Felix, Schettler, Anna, Schwarzkopf, Daniel, Thomas-Rüddel, Daniel, Proquitté, Hans, Reinhart, Konrad and Fleischmann-Struzek, Carolin (2021). Epidemiology of sepsis among children and neonates in Germany: Results from an observational study based on nationwide diagnosis-related groups data between 2010 and 2016∗. Critical Care Medicine, 49 (7), 1049-1057. doi: 10.1097/CCM.0000000000004919

Final year nursing student's exposure to education and knowledge about sepsis: a multi-university study

Harley, Amanda, Massey, Debbie, Ullman, Amanda J., Reid-Searl, Kerry, Schlapbach, Luregn J., Takashima, Mari, Venkatesh, Bala, Datta, Rachit and Johnston, Amy N.B. (2021). Final year nursing student's exposure to education and knowledge about sepsis: a multi-university study. Nurse Education Today, 97 104703, 104703. doi: 10.1016/j.nedt.2020.104703

Acute kidney injury: epidemiology and course in critically ill children

Tai, Chian Wern, Gibbons, Kristen, Schibler, Andreas, Schlapbach, Luregn J. and Raman, Sainath (2021). Acute kidney injury: epidemiology and course in critically ill children. Journal of Nephrology, 35 (2), 559-565. doi: 10.1007/s40620-021-01071-5

Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections' Collaborative of the European Society of Pediatric and Neonatal Intensive Care

Rimensberger, Peter C., Kneyber, Martin C. J., Deep, Akash, Bansal, Mehak, Hoskote, Aparna, Javouhey, Etienne, Jourdain, Gilles, Latten, Lynne, MacLaren, Graeme, Morin, Luc, Pons-Odena, Marti, Ricci, Zaccaria, Singh, Yogen, Schlapbach, Luregn J., Scholefield, Barnaby R., Terheggen, Ulrich, Tissières, Pierre, Tume, Lyvonne N., Verbruggen, Sascha, Brierley, Joe and European Society of Pediatric and Neonatal Intensive Care (ESPNIC) Scientific Sections’ Collaborative Group (2021). Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections' Collaborative of the European Society of Pediatric and Neonatal Intensive Care. Pediatric Critical Care Medicine, 22 (1), 56-67. doi: 10.1097/PCC.0000000000002599

Reducing the global burden of sepsis: a positive legacy for the COVID-19 pandemic?

Reinhart, K., Levy, M. M., Finfer, Simon S., Machado, F., Kaplan, L., Kesecioglu, J., Rhodes, A., Daniels, R., Kissoon, N., Nsutebu, E., Gorordo, L. A., Malik, I., Alhawsawi, A., Cecconi, M., Giamarellos, E., Martin, G., Schlapbach, L. and The European Society of Intensive Care Medicine (ESICM), (2021). Reducing the global burden of sepsis: a positive legacy for the COVID-19 pandemic?. Intensive Care Medicine, 47 (7), 733-736. doi: 10.1007/s00134-021-06409-y

Accuracy of a modified qSOFA score for predicting critical care admission in febrile children

Romaine, Sam T., Potter, Jessica, Khanijau, Aakash, McGalliard, Rachel J., Wright, Jemma L., Sefton, Gerri, Leigh, Simon, Edwardson, Karl, Johnston, Philip, Kerr, Anne, Schlapbach, Luregn J., Pallmann, Philip and Carrol, Enitan D. (2020). Accuracy of a modified qSOFA score for predicting critical care admission in febrile children. Pediatrics, 146 (4) e20200782, e20200638. doi: 10.1542/peds.2020-0782

Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis

Ramanathan, Kollengode, Yeo, Nicholas, Alexander, Peta, Raman, Lakshmi, Barbaro, Ryan, Tan, Chuen Seng, Schlapbach, Luregn J. and MacLaren, Graeme (2020). Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis. Critical Care, 24 (1) 684, 684. doi: 10.1186/s13054-020-03418-z

Editorial: Sepsis in Neonates and Children

Giannoni, Eric and Schlapbach, Luregn J. (2020). Editorial: Sepsis in Neonates and Children. Frontiers in Pediatrics, 8 621663, 621663. doi: 10.3389/fped.2020.621663

Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the australian public health care system

Lunke, Sebastian, Eggers, Stefanie, Wilson, Meredith, Patel, Chirag, Barnett, Christopher P., Pinner, Jason, Sandaradura, Sarah A., Buckley, Michael F., Krzesinski, Emma I., de Silva, Michelle G., Brett, Gemma R., Boggs, Kirsten, Mowat, David, Kirk, Edwin P., Adès, Lesley C., Akesson, Lauren S., Amor, David J., Ayres, Samantha, Baxendale, Anne, Borrie, Sarah, Bray, Alessandra, Brown, Natasha J., Chan, Cheng Yee, Chong, Belinda, Cliffe, Corrina, Delatycki, Martin B., Edwards, Matthew, Elakis, George, Fahey, Michael C. ... Stark, Zornitza (2020). Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the australian public health care system. Obstetrical and Gynecological Survey, 75 (11), 662-664. doi: 10.1097/01.ogx.0000722040.32795.04

Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the era of coronavirus disease 2019∗

Weiss, Scott L., Peters, Mark J., Agus, Michael S. D., Alhazzani, Waleed, Choong, Karen, Flori, Heidi R., Inwald, David P., Nadel, Simon, Nunnally, Mark E., Schlapbach, Luregn J., Tasker, Robert C., Tissieres, Pierre and Kissoon, Niranjan (2020). Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the era of coronavirus disease 2019∗. Pediatric Critical Care Medicine, 21 (11), E1031-E1037. doi: 10.1097/PCC.0000000000002553

Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes

Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyareva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J., Reiss, Irwin K. M. and Infection, Inflammation, Immunology and Immunisation (I4) section of the ESPR (2020). Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatric Research, 90 (1), 232-232. doi: 10.1038/s41390-020-01221-8

Sepsis hysteria? Not for children

Sanchez-Pinto, L Nelson, González-Dambrauskas, Sebastián, Jabornisky, Roberto, Naidoo, Kuban, Schlapbach, Luregn J and Kissoon, Niranjan (2020). Sepsis hysteria? Not for children. The Lancet, 396 (10259), 1332-1333. doi: 10.1016/S0140-6736(20)32148-6

Adapting Pediatric Sepsis Criteria for Benchmarking and Quality Control - The Search for the Holy Grail Continues

Schlapbach, Luregn J. and Watson, R. Scott (2020). Adapting Pediatric Sepsis Criteria for Benchmarking and Quality Control - The Search for the Holy Grail Continues. Critical Care Medicine, 48 (10), 1549-1551. doi: 10.1097/CCM.0000000000004535

Updates on pediatric sepsis

Cruz, Andrea T., Lane, Roni D., Balamuth, Fran, Aronson, Paul L., Ashby, David W., Neuman, Mark I., Souganidis, Ellie S., Alpern, Elizabeth R. and Schlapbach, Luregn J. (2020). Updates on pediatric sepsis. Journal of the American College of Emergency Physicians open, 1 (5), 981-993. doi: 10.1002/emp2.12173

Febrile children in the Emergency Department: frequency and predictors of poor outcome

Long, Elliot, Solan, Tom, Stephens, David J., Schlapbach, Luregn J., Williams, Amanda, Tse, Wai Chung and Babl, Franz E. (2020). Febrile children in the Emergency Department: frequency and predictors of poor outcome. Acta Paediatrica, International Journal of Paediatrics, 110 (3) apa.15602, 1046-1055. doi: 10.1111/apa.15602

C-Reactive Protein, Procalcitonin, and White Blood Count to Rule Out Neonatal Early-onset Sepsis Within 36 Hours: A Secondary Analysis of the Neonatal Procalcitonin Intervention Study

Stocker, Martin, van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien W., Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, F Kornelisse, René, van Gijsel, Juliette, Visser, Eline G., Plötz, Frans B., Heath, Paul, Achten, Niek B., Lehnick, Dirk and van Rossum, Annemarie M. C. (2020). C-Reactive Protein, Procalcitonin, and White Blood Count to Rule Out Neonatal Early-onset Sepsis Within 36 Hours: A Secondary Analysis of the Neonatal Procalcitonin Intervention Study. Clinical Infectious Diseases, 73 (2), e383-e390. doi: 10.1093/cid/ciaa876

First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service

Gc, Vijay S., Franklin, Donna, Whitty, Jennifer A., Dalziel, Stuart R., Babl, Franz E., Schalpbach, Luregn J., Fraser, John F., Craig, Simon, Neutze, Jocelyn, Oakley, Ed and Schibler, Andreas (2020). First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service. Archives of Disease in Childhood, 105 (10), 975-980. doi: 10.1136/archdischild-2019-318427

World Sepsis Day: a global agenda to target a leading cause of morbidity and mortality

Schlapbach, Luregn J., Kissoon, Niranjan, Alhawsawi, Abdulelah, Aljuaid, Maha H., Daniels, Ron, Gorordo-Delsol, Luis A., Machado, Flavia, Malik, Imrana, Nsutebu, Emmanuel Fru, Finfer, Simon and Reinhart, Konrad (2020). World Sepsis Day: a global agenda to target a leading cause of morbidity and mortality. American Journal of Physiology-Lung Cellular and Molecular Physiology, 319 (3), L518-L522. doi: 10.1152/ajplung.00369.2020

Extracorporeal membrane oxygenation for group B streptococcal sepsis in neonates: a retrospective study of the extracorporeal life support organization registry

Schlapbach, Luregn J., Chatfield, Mark D., Rycus, Peter and MacLaren, Graeme (2020). Extracorporeal membrane oxygenation for group B streptococcal sepsis in neonates: a retrospective study of the extracorporeal life support organization registry. Pediatric Critical Care Medicine, 21 (8), e505-e512. doi: 10.1097/PCC.0000000000002320

Gestational age and risk of mortality in term-born critically ill neonates admitted to PICUs in Australia and New Zealand*

Namachivayam, Siva P., Carlin, John B., Millar, Johnny, Alexander, Janet, Edmunds, Sarah, Ganeshalingham, Anusha, Lew, Jamie, Erickson, Simon, Butt, Warwick, Schlapbach, Luregn J., Ganu, Subodh, Festa, Marino, Egan, Jonathan R., Williams, Gary and Young, Janelle (2020). Gestational age and risk of mortality in term-born critically ill neonates admitted to PICUs in Australia and New Zealand*. Critical Care Medicine, 48 (8), E648-E656. doi: 10.1097/CCM.0000000000004409

Paediatric patient stratification in the emergency department

Balamuth, Fran and Schlapbach, Luregn J. (2020). Paediatric patient stratification in the emergency department. The Lancet Child and Adolescent Health, 4 (8), 557-558. doi: 10.1016/S2352-4642(20)30208-X

Biomarkers for the discrimination of acute Kawasaki disease from infections in childhood

Zandstra, Judith, van de Geer, Annemarie, Tanck, Michael W. T., van Stijn-Bringas Dimitriades, Diana, Aarts, Cathelijn E. M., Dietz, Sanne M., van Bruggen, Robin, Schweintzger, Nina A., Zenz, Werner, Emonts, Marieke, Zavadska, Dace, Pokorn, Marko, Usuf, Effua, Moll, Henriette A., Schlapbach, Luregn J., Carrol, Enitan D., Paulus, Stephane, Tsolia, Maria, Fink, Colin, Yeung, Shunmay, Shimizu, Chisato, Tremoulet, Adriana, Galassini, Rachel, Wright, Victoria J., Martinón-Torres, Federico, Herberg, Jethro, Burns, Jane, Levin, Michael and Kuijpers, Taco W. (2020). Biomarkers for the discrimination of acute Kawasaki disease from infections in childhood. Frontiers in Pediatrics, 8 355, 355. doi: 10.3389/fped.2020.00355

Editorial: The immunology of sepsis—understanding host susceptibility, pathogenesis of disease, and avenues for future treatment

Schlapbach, Luregn J., Trück, Johannes and Roger, Thierry (2020). Editorial: The immunology of sepsis—understanding host susceptibility, pathogenesis of disease, and avenues for future treatment. Frontiers in Immunology, 11 1263, 1263. doi: 10.3389/fimmu.2020.01263

Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the Australian public health care system

Lunke, Sebastian, Eggers, Stefanie, Wilson, Meredith, Patel, Chirag, Barnett, Christopher P., Pinner, Jason, Sandaradura, Sarah A., Buckley, Michael F., Krzesinski, Emma I., De Silva, Michelle G., Brett, Gemma R., Boggs, Kirsten, Mowat, David, Kirk, Edwin P., Adès, Lesley C., Akesson, Lauren S., Amor, David J., Ayres, Samantha, Baxendale, Anne, Borrie, Sarah, Bray, Alessandra, Brown, Natasha J., Chan, Cheng Yee, Chong, Belinda, Cliffe, Corrina, Delatycki, Martin B., Edwards, Matthew, Elakis, George, Fahey, Michael C. ... Stark, Zornitza (2020). Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the Australian public health care system. JAMA - Journal of the American Medical Association, 323 (24), 2503-2511. doi: 10.1001/jama.2020.7671

Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care

Raman, Sainath, Tai, Chian Wern, Le Marsney, Renate, Schibler, Andreas, Gibbons, Kristen and Schlapbach, Luregn J. (2020). Prediction of Acute Kidney Injury on Admission to Pediatric Intensive Care. Pediatric Critical Care Medicine, Publish Ahead of Print (9), 811-819. doi: 10.1097/pcc.0000000000002411

Enteral hydration in high-flow therapy for infants with bronchiolitis: secondary analysis of a randomised trial

Babl, Franz E., Franklin, Donna, Schlapbach, Luregn J., Oakley, Ed, Dalziel, Stuart, Whitty, Jennifer A., Neutze, Jocelyn, Furyk, Jeremy, Craig, Simon, Fraser, John F., Jones, Mark and Schibler, Andreas (2020). Enteral hydration in high-flow therapy for infants with bronchiolitis: secondary analysis of a randomised trial. Journal of Paediatrics and Child Health, 56 (6) jpc.14799, 950-955. doi: 10.1111/jpc.14799

Pediatric Sepsis Definition-A Systematic Review Protocol by the Pediatric Sepsis Definition Taskforce

Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Chiotos, Kathleen, Chisti, Mohammod Jobayer, Hamid, Jemila, Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Oliveira, Cláudio Flauzino, Peters, Mark, Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Sorce, Lauren R. and for the Pediatric Sepsis Definition Taskforce of the Society of Critical Care Medicine (2020). Pediatric Sepsis Definition-A Systematic Review Protocol by the Pediatric Sepsis Definition Taskforce. Critical Care Explorations, 2 (6), e0123. doi: 10.1097/CCE.0000000000000123

A rare mutation in SPLUNC1 affects bacterial adherence and invasion in meningococcal disease

Mashbat, Bayarchimeg, Bellos, Evangelos, Hodeib, Stephanie, Bidmos, Fadil, Thwaites, Ryan S., Lu, Yaxuan, Wright, Victoria J., Herberg, Jethro A., Klobassa, Daniela S., Zenz, Werner, Hansel, Trevor T., Nadel, Simon, Langford, Paul R., Schlapbach, Luregn J., Li, Ming-Shi, Redinbo, Matthew R., Di, Y Peter, Levin, Michael and Sancho-Shimizu, Vanessa (2020). A rare mutation in SPLUNC1 affects bacterial adherence and invasion in meningococcal disease. Clinical Infectious Diseases, 70 (10), 2045-2053. doi: 10.1093/cid/ciz600

Neonatal sepsis: need for consensus definition, collaboration and core outcomes

Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyaeva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J. and Reiss, Irwin K. M. (2020). Neonatal sepsis: need for consensus definition, collaboration and core outcomes. Pediatric Research, 88 (1), 2-4. doi: 10.1038/s41390-020-0850-5

Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study

Borghesi, Alessandro, Trück, Johannes, Asgari, Samira, Sancho-Shimizu, Vanessa, Agyeman, Philipp K. A., Bellos, Evangelos, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Natalucci, Giancardlo, Relly, Christa, Riedel, Thomas, Kuehni, Claudia E., Thorball, Christian W., Chaturvedi, Nimisha, Martinon-Torres, Federico, Kuijpers, Taco W., Coin, Lachlan, Wright, Victoria, Herberg, Jethro, Levin, Michael, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn J. and EUCLIDS consortium and the Swiss Paediatric Sepsis Study (2020). Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study. Clinical Infectious Diseases, 71 (10), E614-E623. doi: 10.1093/cid/ciaa290

Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes

Moynihan, Katie M., McGarvey, Tambra, Barlow, Andrew, Heney, Claire, Gibbons, Kristen, Clark, Julia E., Schlebusch, Sanmarié and Schlapbach, Luregn J. (2020). Testing for Common Respiratory Viruses in Children Admitted to Pediatric Intensive Care: Epidemiology and Outcomes. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 21 (6), 1-e341. doi: 10.1097/PCC.0000000000002302

Nosocomial infections during extracorporeal membrane oxygenation in neonatal, pediatric, and adult patients: a comprehensive narrative review

MacLaren, Graeme, Schlapbach, Luregn J. and Aiken, Alexander M. (2020). Nosocomial infections during extracorporeal membrane oxygenation in neonatal, pediatric, and adult patients: a comprehensive narrative review. Pediatric Critical Care Medicine, 21 (3), 283-290. doi: 10.1097/PCC.0000000000002190

Executive summary: Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F M, Joshi, Poonam, Karam, Oliver, Kneyber, Martin C J ... Tissieres, Pierre (2020). Executive summary: Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatric Critical Care Medicine, 21 (2), 186-195. doi: 10.1097/PCC.0000000000002197

Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F M, Joshi, Poonam, Karam, Oliver, Kneyber, Martin C J ... Tissieres, Pierre (2020). Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Medicine, 46 (S1), 1-9. doi: 10.1007/s00134-019-05877-7

Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S D, Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F. M., Joshi, Poonam, Karam, Oliver, Kneyber, Martin C. J. ... Tissieres, Pierre (2020). Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatric Critical Care Medicine, 21 (2), e52-e106. doi: 10.1097/PCC.0000000000002198

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

Weiss, Scott L., Peters, Mark J., Alhazzani, Waleed, Agus, Michael S. D., Flori, Heidi R., Inwald, David P., Nadel, Simon, Schlapbach, Luregn J., Tasker, Robert C., Argent, Andrew C., Brierley, Joe, Carcillo, Joseph, Carrol, Enitan D., Carroll, Christopher L., Cheifetz, Ira M., Choong, Karen, Cies, Jeffry J., Cruz, Andrea T., De Luca, Daniele, Deep, Akash, Faust, Saul N., De Oliveira, Claudio Flauzino, Hall, Mark W., Ishimine, Paul, Javouhey, Etienne, Joosten, Koen F. M., Joshi, Poonam, Karam, Oliver, Kneyber, Martin C. J. ... Tissieres, Pierre (2020). Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Medicine, 46 (S1), 10-67. doi: 10.1007/s00134-019-05878-6

Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019)

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2020). Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019). Frontiers in Pediatrics, 7 538, 538. doi: 10.3389/fped.2019.00538

Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2)

Franklin, Donna, Shellshear, Deborah, Babl, Franz E., Schlapbach, Luregn J., Oakley, Ed, Borland, Meredith L., Hoeppner, Tobias, George, Shane, Craig, Simon, Neutze, Jocelyn, Williams, Amanda, Acworth, Jason, McCay, Hamish, Wallace, Alex, Mattes, Joerg, Gangathimn, Vinay, Wildman, Mark, Fraser, John F, Moloney, Susan, Gavranich, John, Waugh, John, Hobbins, Sue, Fahy, Rose, Grew, Simon, Gannon, Brenda, Gibbons, Kristen, Dalziel, Stuart and Schibler, Andreas (2019). Multicentre, randomised trial to investigate early nasal high—flow therapy in paediatric acute hypoxaemic respiratory failure: a protocol for a randomised controlled trial—a Paediatric Acute respiratory Intervention Study (PARIS 2). BMJ Open, 9 (12) e030516, e030516. doi: 10.1136/bmjopen-2019-030516

Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study

Schlapbach, Luregn J., Chiletti, Roberto, Straney, Lahn, Festa, Marino, Alexander, Daniel, Butt, Warwick and MacLaren, Graeme (2019). Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study. Critical Care, 23 (1) 429, 429. doi: 10.1186/s13054-019-2685-1

Translational gap in pediatric septic shock management: an ESPNIC perspective

Morin, Luc, Kneyber, Martin, Jansen, Nicolaas J. G., Peters, Mark J., Javouhey, Etienne, Nadel, Simon, Maclaren, Graeme, Schlapbach, Luregn Jan and Tissieres, Pierre (2019). Translational gap in pediatric septic shock management: an ESPNIC perspective. Annals of Intensive Care, 9 (1) 73, 73. doi: 10.1186/s13613-019-0545-4

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Wang, Xinzhu, Nijman, Ruud, Camuzeaux, Stephane, Sands, Caroline, Jackson, Heather, Kaforou, Myrsini, Emonts, Marieke, Herberg, Jethro A., Maconochie, Ian, Carrol, Enitan D., Paulus, Stephane C., Zenz, Werner, Van der Flier, Michiel, de Groot, Ronald, Martinon-Torres, Federico, Schlapbach, Luregn J., Pollard, Andrew J., Fink, Colin, Kuijpers, Taco T., Anderson, Suzanne, Lewis, Matthew R., Levin, Michael, McClure, Myra and & EUCLIDS consortium (2019). Plasma lipid profiles discriminate bacterial from viral infection in febrile children. Scientific Reports, 9 (1) 17714, 17714. doi: 10.1038/s41598-019-53721-1

Burden of Streptococcus pneumoniae sepsis in children after introduction of pneumococcal conjugate vaccines: a prospective population-based cohort study

Asner, Sandra A., Agyeman, Philipp K. A., Gradoux, Eugénie, Posfay-Barbe, Klara M., Heininger, Ulrich, Giannoni, Eric, Crisinel, Pierre A., Stocker, Martin, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Hasters, Paul, Relly, Christa, Baer, Walter, Aebi, Christoph, Schlapbach, Luregn J. and Berger, Christoph (2019). Burden of Streptococcus pneumoniae sepsis in children after introduction of pneumococcal conjugate vaccines: a prospective population-based cohort study. Clinical Infectious Diseases, 69 (9), 1574-1580. doi: 10.1093/cid/ciy1139

The WHO resolution on sepsis: what action is needed in Australia?

Schlapbach, Luregn J, Thompson, Kelly and Finfer, Simon R (2019). The WHO resolution on sepsis: what action is needed in Australia?. Medical Journal of Australia, 211 (9), 395-397.e1. doi: 10.5694/mja2.50279

Polymerase chain reaction for human parechovirus on blood samples improves detection of clinical infections in infants

May, M. L. A., Tozer, S., Day, R., Doyle, R., Bernard, A., Schlapbach, L. J., Heney, C., Clark, J. E. and Bialasiewicz, S. (2019). Polymerase chain reaction for human parechovirus on blood samples improves detection of clinical infections in infants. Molecular Biology Reports, 47 (1), 715-720. doi: 10.1007/s11033-019-05151-5

Nasal high flow in room air for hypoxemic bronchiolitis infants

Franklin, Donna, Babl, Franz E., Gibbons, Kristen, Pham, Trang M. T., Hasan, Nadia, Schlapbach, Luregn J., Oakley, Ed, Craig, Simon, Furyk, Jeremy, Neutze, Jocelyn, Moloney, Susan, Gavranich, John, Shirkhedkar, Prasanna, Kapoor, Vishal, Grew, Simon, Fraser, John F., Dalziel, Stuart, Schibler, Andreas and and PARIS and PREDICT (2019). Nasal high flow in room air for hypoxemic bronchiolitis infants. Frontiers in Pediatrics, 7 426, 426. doi: 10.3389/fped.2019.00426

Paediatric sepsis

Schlapbach, Luregn J. (2019). Paediatric sepsis. Current Opinion in Infectious Diseases, 32 (5), 497-504. doi: 10.1097/QCO.0000000000000583

Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: A systematic review and meta-analysis

Achten, Niek B., Klingenberg, Claus, Benitz, William E., Stocker, Martin, Schlapbach, Luregn J., Giannoni, Eric, Bokelaar, Robin, Driessen, Gertjan J. A., Brodin, Petter, Uthaya, Sabita, Van Rossum, Annemarie M. C. and Plötz, Frans B. (2019). Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: A systematic review and meta-analysis. JAMA Pediatrics, 173 (11), 1032-1040. doi: 10.1001/jamapediatrics.2019.2825

Bacteremia in childhood life-threatening infections in Urban Gambia: EUCLIDS in West Africa

Secka, F., Herberg, J. A., Sarr, I., Darboe, S., Sey, G., Saidykhan, M., Wathuo, M., Kaforou, M., Antonio, M., Roca, A., Zaman, S. M.A., Cebey-López, M., Boeddha, N. P., Paulus, S., Kohlfürst, D. S., Emonts, M., Zenz, W., Carrol, E. D., De Groot, R., Schlapbach, L., Martinon-Torres, F., Bojang, K., Levin, M., Van Der Flier, M. and Anderson, S. T. (2019). Bacteremia in childhood life-threatening infections in Urban Gambia: EUCLIDS in West Africa. Open Forum Infectious Diseases, 6 (9) ofz332, ofz332. doi: 10.1093/ofid/ofz332

Epidemiology of childhood death in Australian and New Zealand intensive care units

Moynihan, Katie M., Alexander, Peta M. A., Schlapbach, Luregn J., Millar, Johnny, Jacobe, Stephen, Ravindranathan, Hari, Croston, Elizabeth J., Staffa, Steven J., Burns, Jeffrey P. and Gelbart, Ben (2019). Epidemiology of childhood death in Australian and New Zealand intensive care units. Intensive Care Medicine, 45 (9), 1262-1271. doi: 10.1007/s00134-019-05675-1

Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial

Schlapbach, Luregn J., Horton, Stephen Brian, Long, Debbie Amanda, Beca, John, Erickson, Simon, Festa, Marino, d’Udekem, Yves, Alphonso, Nelson, Winlaw, David, Johnson, Kerry, Delzoppo, Carmel, van Loon, Kim, Gannon, B., Fooken, Jonas, Blumenthal, Antje, Young, Paul, Jones, Mark, Butt, Warwick and Schibler, Andreas (2019). Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial. BMJ Open, 9 (8) e026664, e026664. doi: 10.1136/bmjopen-2018-026664

Infections on extracorporeal life support in adults and children-a survey of international practice on prevention, diagnosis, and treatment

Farrell, Deborah, MacLaren, Graeme and Schlapbach, Luregn J. (2019). Infections on extracorporeal life support in adults and children-a survey of international practice on prevention, diagnosis, and treatment. Pediatric Critical Care Medicine, 20 (7), 667-671. doi: 10.1097/PCC.0000000000001941

Insertion, management, and complications associated with arterial catheters in paediatric intensive care: a clinical audit

Schults, Jessica A., Long, Debbie, Pearson, Kylie, Takashima, Mari, Baveas, Thimitra, Schlapbach, Luregn J., Macfarlane, Fiona and Ullman, Amanda J. (2019). Insertion, management, and complications associated with arterial catheters in paediatric intensive care: a clinical audit. Australian Critical Care, 33 (4), 326-332. doi: 10.1016/j.aucc.2019.05.003

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Borghini, Lisa, Png, Eileen, Binder, Alexander, Wright, Victoria J., Pinnock, Ellie, de Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van der Flier, Michiel, Schlapbach, Luregn J., Anderson, Suzanne, Secka, Fatou, Salas, Antonio, Fink, Colin, Carrol, Enitan D., Pollard, Andrew J., Coin, Lachlan J., Kuijpers, Taco W., Martinon-Torres, Federico, Zenz, Werner, Levin, Michael, Hibberd, Martin L., Davila, Sonia and EUCLIDS consortium (2019). Identification of regulatory variants associated with genetic susceptibility to meningococcal disease. Scientific Reports, 9 (1) 6966, 6966. doi: 10.1038/s41598-019-43292-6

The role of parental concerns in the recognition of sepsis in children: A literature review

Harley, Amanda, Latour, Jos and Schlapbach, Luregn J. (2019). The role of parental concerns in the recognition of sepsis in children: A literature review. Frontiers in Pediatrics, 7 (APR) 161, 161. doi: 10.3389/fped.2019.00161

Global paediatric critical care research: mind the gaps

Schlapbach, Luregn J., Gelbart, Ben, Gelbart, Ben, Festa, Marino, The Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), Kanthimathinathan, Hari Krishnan, Peters, M. J. and Long, Debbie (2019). Global paediatric critical care research: mind the gaps. Intensive Care Medicine, 45 (5), 753-754. doi: 10.1007/s00134-019-05571-8

Transforming data into a crystal ball-predicting outcomes after extracorporeal membrane oxygenation

MacLaren, Graeme, Cho, Hwa Jin and Schlapbach, Luregn J. (2019). Transforming data into a crystal ball-predicting outcomes after extracorporeal membrane oxygenation. Pediatric Critical Care Medicine, 20 (5), 490-491. doi: 10.1097/PCC.0000000000001910

Reducing collateral damage from mandates for time to antibiotics in pediatric sepsis - primum non nocere

Schlapbach, Luregn J., Weiss, Scott L. and Wolf, Joshua (2019). Reducing collateral damage from mandates for time to antibiotics in pediatric sepsis - primum non nocere. JAMA Pediatrics, 173 (5), E1-E2. doi: 10.1001/jamapediatrics.2019.0174

Applying Sepsis-3 criteria for septic shock to children-not as shocking as at first sight?*

Schlapbach, Luregn J. and Argent, Andrew (2019). Applying Sepsis-3 criteria for septic shock to children-not as shocking as at first sight?*. Pediatric Critical Care Medicine, 20 (3), 299-300. doi: 10.1097/PCC.0000000000001884

Transnasal humidified rapid insufflation ventilatory exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial

George, Shane, Humphreys, Susan, Williams, Tara, Gelbart, Ben, Chavan, Arjun, Rasmussen, Katie, Ganeshalingham, Anusha, Erickson, Simon, Ganu, Subodh Suhas, Singhal, Nitesh, Foster, Kelly, Gannon, Brenda, Gibbons, Kristen, Schlapbach, Luregn J, Festa, Marino, Dalziel, Stuart and Schibler, Andreas (2019). Transnasal humidified rapid insufflation ventilatory exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial. BMJ Open, 9 (2) e025997. doi: 10.1136/bmjopen-2018-025997

Paediatric intensive care admissions during the 2015-2016 Queensland human parechovirus outbreak: parechovirus intensive care admissions

McKenna, Ronan, Joseph, Lindsay, Sargent, Philip, May, Meryta, Tozer, Sarah, Bialasiewicz, Seweryn, Heney, Claire, Schlapbach, Luregn J. and Clark, Julia E. (2019). Paediatric intensive care admissions during the 2015-2016 Queensland human parechovirus outbreak: parechovirus intensive care admissions. Journal of Paediatrics and Child Health, 55 (8), 968-974. doi: 10.1111/jpc.14336

Sepsis: changing definitions, unchanging treatment

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425

Attitudes of Australian health professionals towards rapid genomic testing in neonatal and paediatric intensive care

Stark, Zornitza, Nisselle, Amy, McClaren, Belinda, Lynch, Fiona, Best, Stephanie, Long, Janet C., Martyn, Melissa, Patel, Chirag, Schlapbach, Luregn J., Barnett, Christopher, Theda, Christiane, Pinner, Jason, Dinger, Marcel E., Lunke, Sebastian and Gaff, Clara L. (2019). Attitudes of Australian health professionals towards rapid genomic testing in neonatal and paediatric intensive care. European Journal of Human Genetics, 27 (10), 1493-1501. doi: 10.1038/s41431-019-0429-y

Viral respiratory infections diagnosed after PICU admission

Moynihan, Katie M., Barlow, Andrew, Heney, Claire, Clark, Julia E., Schlebusch, Sanmarie and Schlapbach, Luregn J. (2019). Viral respiratory infections diagnosed after PICU admission. Pediatric Critical Care Medicine, 20 (1), E46-E50. doi: 10.1097/PCC.0000000000001757

Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care

Moynihan, Katie M., Barlow, Andrew, Nourse, Clare, Heney, Claire, Schlebusch, Sanmarié and Schlapbach, Luregn J. (2018). Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care. The Pediatric infectious disease journal, 37 (12), e336-e338. doi: 10.1097/INF.0000000000002029

Prolonged postoperative vasoplegia in pediatric patients on chronic angiotensin II blocker treatment

Pandya, Nischal R., Alphonso, Nelson, Tu, Quyen, Venugopal, Prem and Schlapbach, Luregn J. (2018). Prolonged postoperative vasoplegia in pediatric patients on chronic angiotensin II blocker treatment. Frontiers in Cardiovascular Medicine, 5 121, 121. doi: 10.3389/fcvm.2018.00121

Time-to-positivity of blood cultures in children with sepsis

Dierig, Alexa, Berger, Christoph, Agyeman, Philipp K. A., Bernhard-Stirnemann, Sara, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Hasters, Paul, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Schlapbach, Luregn J. and Heininger, Ulrich (2018). Time-to-positivity of blood cultures in children with sepsis. Frontiers in Pediatrics, 6 222, 222. doi: 10.3389/fped.2018.00222

Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study

Giannoni, Eric, Agyeman, Philipp K. A., Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Spycher, Ben D., Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Riedel, Thomas, Kuehni, Claudia, Aebi, Christoph, Berger, Christoph, Schlapbach, Luregn J. and Swiss Pediatric Sepsis Study (2018). Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study. The Journal of Pediatrics, 201, 106-114.e4. doi: 10.1016/j.jpeds.2018.05.048

Postoperative catecholamine resistance following fetal methamphetamine exposure

Perumal, Gopinath, Marathe, Supreet P., Schlapbach, Luregn J., Morwood, Jim, Venugopal, Prem and Alphonso, Nelson (2018). Postoperative catecholamine resistance following fetal methamphetamine exposure. Asian Cardiovascular & Thoracic Annals, 27 (1), 218492318784740-32. doi: 10.1177/0218492318784740

Fluid bolus therapy in critically ill children: a survey of practice among paediatric intensive care doctors in Australia and New Zealand

Gelbart, Ben, Schlapbach, Luregn, Ganeshalingham, Anusha, Ganu, Subodh, Erickson, Simon, Oberender, Felix, Hoq, Monsurul, Williams, Gary, George, Shane, Festa, Marino, Paediatric Study Group of the Australian and New Zealand Intensive Care Society and Long, Debbie (2018). Fluid bolus therapy in critically ill children: a survey of practice among paediatric intensive care doctors in Australia and New Zealand. Critical Care and Resuscitation, 20 (2), 131-138.

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

Martinón-Torres, Federico, Salas, Antonio, Rivero-Calle, Irene, Cebey-López, Miriam, Pardo-Seco, Jacobo, Herberg, Jethro A, Boeddha, Navin P, Klobassa, Daniela S, Secka, Fatou, Paulus, Stephane, de Groot, Ronald, Schlapbach, Luregn J, Driessen, Gertjan J, Anderson, Suzanne T, Emonts, Marieke, Zenz, Werner, Carrol, Enitan D, Van der Flier, Michiel, Levin, Michael, Levin, Michael, Coin, Lachlan, Gormley, Stuart, Hamilton, Shea, Herberg, Jethro, Hourmat, Bernardo, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Wright, Victoria ... EUCLIDS Consortium (2018). Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet Child and Adolescent Health, 2 (6), 404-414. doi: 10.1016/S2352-4642(18)30113-5

Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus

Kawasaki, Tatsuya, Shime, Nobuaki, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus. Intensive Care Medicine, 44 (6), 995-997. doi: 10.1007/s00134-018-5188-7

SIRS in the time of sepsis-3: what about the children?

Schlapbach, Luregn J., Berger, Christoph, Aebi, Christoph and Agyeman, Philipp K.A. (2018). SIRS in the time of sepsis-3: what about the children?. Chest, 153 (6), 1512-1512. doi: 10.1016/j.chest.2018.02.037

Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)

Boeddha, Navin P., Schlapbach, Luregn J., Driessen, Gertjan J., Herberg, Jethro A., Rivero-Calle, Irene, Cebey-López, Miriam, Klobassa, Daniela S., Philipsen, Ria, de Groot, Ronald, Inwald, David P., Nadel, Simon, Paulus, Stéphane, Pinnock, Eleanor, Secka, Fatou, Anderson, Suzanne T., Agbeko, Rachel S., Berger, Christoph, Fink, Colin G., Carrol, Enitan D., Zenz, Werner, Levin, Michael, van der Flier, Michiel, Martinón-Torres, Federico, Hazelzet, Jan A., Emonts, Marieke and EUCLIDS consortium (2018). Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS). Critical Care, 22 (1) 143, 143. doi: 10.1186/s13054-018-2052-7

Evaluation of a paediatric clinical ethics service

Jansen, Melanie A., Schlapbach, Luregn J. and Irving, Helen (2018). Evaluation of a paediatric clinical ethics service. Journal of Paediatrics and Child Health, 54 (11), 1199-1205. doi: 10.1111/jpc.13933

A randomized trial of high-flow oxygen therapy in infants with bronchiolitis

Franklin, Donna, Babl, Franz E, Schlapbach, Luregn J, Oakley, Ed, Craig, Simon, Neutze, Jocelyn, Furyk, Jeremy, Fraser, John F, Jones, Mark, Whitty, Jennifer A, Dalziel, Stuart R. and Schibler, Andreas (2018). A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. New England Journal of Medicine, 378 (12), 1121-1131. doi: 10.1056/NEJMoa1714855

Which organ dysfunction scores to use in children with infection?

Leclerc, Francis, Duhamel, Alain, Leteurtre, Stéphane, Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme, Pilcher, David and Schlapbach, Luregn J. (2018). Which organ dysfunction scores to use in children with infection?. Intensive Care Medicine, 44 (5), 697-698. doi: 10.1007/s00134-018-5123-y

Extracorporeal membrane oxygenation for pertussis: predictors of outcome including pulmonary hypertension and leukodepletion

Domico, Michele, Ridout, Deborah, MacLaren, Graeme, Barbaro, Ryan, Annich, Gail, Schlapbach, Luregn J. and Brown, Katherine L. (2018). Extracorporeal membrane oxygenation for pertussis: predictors of outcome including pulmonary hypertension and leukodepletion. Pediatric Critical Care Medicine, 19 (3), 254-261. doi: 10.1097/PCC.0000000000001454

The global burden of paediatric and neonatal sepsis: a systematic review

Fleischmann-Struzek, Carolin, Goldfarb, David M., Schlattmann, Peter, Schlapbach, Luregn J., Reinhart, Konrad and Kissoon, Niranjan (2018). The global burden of paediatric and neonatal sepsis: a systematic review. The Lancet Respiratory Medicine, 6 (3), 223-230. doi: 10.1016/S2213-2600(18)30063-8

Defining pediatric sepsis

Schlapbach, Luregn J. and Kissoon, Niranjan (2018). Defining pediatric sepsis. JAMA Pediatrics, 172 (4), 312-314. doi: 10.1001/jamapediatrics.2017.5208

Sepsis in children—completely different? Sepsis bei Kindern – alles anders?

Buettcher, M., Schlapbach, L. J. and Stocker, M. (2018). Sepsis in children—completely different? Sepsis bei Kindern – alles anders?. Notfall und Rettungsmedizin, 22 (3), 219-225. doi: 10.1007/s10049-018-0506-8

Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit

Schlapbach, Luregn J., Straney, Lahn, Bellomo, Rinaldo, MacLaren, Graeme and Pilcher, David (2017). Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Medicine, 44 (2), 179-188. doi: 10.1007/s00134-017-5021-8

Nasal high-flow therapy in children: a survey of current practice in Australia

Maul, Clark P., Franklin, Donna, Williams, Tara, Schlapbach, Luregn and Schibler, Andreas (2017). Nasal high-flow therapy in children: a survey of current practice in Australia. Journal of Paediatrics and Child Health, 53 (10), 1031-1032. doi: 10.1111/jpc.13695

Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a prospective population-based cohort study

Agyeman, Philipp, Schlapbach, Luregn J., Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Schindler, Matthias, Korten, Insa, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian R., Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Kuehni, Claudia E., Aebi, Christoph and Berger, Christoph (2017). Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a prospective population-based cohort study. The Lancet Child and Adolescent Health, 1 (2), 124-133. doi: 10.1016/S2352-4642(17)30010-X

Low L-Ficolin associated with disease severity during sepsis in adult ICU patients

Kessler, Ulf, Schlapbach, Luregn J., Klimek, Peter and Jakob, Stephan M. (2017). Low L-Ficolin associated with disease severity during sepsis in adult ICU patients. Liver International, 37 (9), 1409-1409. doi: 10.1111/liv.13448

Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns)

Stocker, Martin, van Herk, Wendy, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien W., Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, Rene F., van Gijsel, Juliette, Visser, Eline G., Willemsen, Sten P. and van Rossum, Annemarie M. C. (2017). Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns). Lancet, 390 (10097), 871-881. doi: 10.1016/S0140-6736(17)31444-7

Time for sepsis-3 in children?

Schlapbach, Luregn J. (2017). Time for sepsis-3 in children?. Pediatric Critical Care Medicine, 18 (8), 805-806. doi: 10.1097/PCC.0000000000001203

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations

Asgari, Samira, Schlapbach, Luregn J., Anchisi, Stéphanie, Hammer, Christian, Bartha, Istvan, Junier, Thomas, Mottet-Osman, Geneviève, Posfay-Barbe, Klara M., Longchamp, David, Stocker, Martin, Cordey, Samuel, Kaiser, Laurent, Riedel, Thomas, Kenna, Tony, Long, Deborah, Schibler, Andreas, Telenti, Amalio, Tapparel, Caroline, McLaren, Paul J., Garcin, Dominique and Fellay, Jacques (2017). Severe viral respiratory infections in children with IFIH1 loss-of-function mutations. Proceedings of the National Academy of Sciences, 114 (31), 8342-8347. doi: 10.1073/pnas.1704259114

Venous vs arterial lactate and 30-day mortality in pediatric sepsis

Schlapbach, Luregn J., MacLaren, Graeme and Straney, Lahn (2017). Venous vs arterial lactate and 30-day mortality in pediatric sepsis. JAMA Pediatrics, 171 (8), 813-813. doi: 10.1001/jamapediatrics.2017.1598

The excess burden of severe sepsis in Indigenous Australian children: can anything be done?

Schlapbach, Luregn J., Ostrowski, Justyna A. and MacLaren, Graeme (2017). The excess burden of severe sepsis in Indigenous Australian children: can anything be done?. Medical Journal of Australia, 207 (1), 45-46. doi: 10.5694/mja17.00464

Burden of disease and change in practice in critically ill infants with bronchiolitis

Schlapbach, Luregn J., Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer A., Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis. European Respiratory Journal, 49 (6) 1601648, 1601648. doi: 10.1183/13993003.01648-2016

Paediatric sepsis: old wine in new bottles?

Schlapbach, Luregn J., Javouhey, Etienne and Jansen, Nicolaas J. G. (2017). Paediatric sepsis: old wine in new bottles?. Intensive Care Medicine, 43 (11), 1-4. doi: 10.1007/s00134-017-4800-6

Impact of viral respiratory pathogens on outcomes after pediatric cardiac surgery

Moynihan, Katie, Barlow, Andrew, Alphonso, Nelson, Anderson, Ben, Johnson, Janelle, Nourse, Clare, Schlebusch, Sanmarié, Karl, Tom R. and Schlapbach, Luregn J. (2017). Impact of viral respiratory pathogens on outcomes after pediatric cardiac surgery. Pediatric Critical Care Medicine, 18 (3), 219-227. doi: 10.1097/PCC.0000000000001083

Targeting Staphylococcus aureus in pediatric surviving sepsis bundles

Schlapbach, Luregn J. and MacLaren, Graeme (2017). Targeting Staphylococcus aureus in pediatric surviving sepsis bundles. JAMA Pediatrics, 171 (3), 301-301. doi: 10.1001/jamapediatrics.2016.4675

Prediction of pediatric sepsis mortality within 1 h of intensive care admission

Schlapbach, Luregn J., MacLaren, Graeme, Festa, Marino, Alexander, Janet, Erickson, Simon, Beca, John, Slater, Anthony, Schibler, Andreas, Pilcher, David, Millar, Johnny and Straney, Lahn (2017). Prediction of pediatric sepsis mortality within 1 h of intensive care admission. Intensive Care Medicine, 43 (8), 1085-1096. doi: 10.1007/s00134-017-4701-8

The burden of invasive infections in critically ill indigenous children in Australia

Ostrowski, Justyna A., Maclaren, Graeme, Alexander, Janet, Stewart, Penny, Gune, Sheena, Francis, Joshua R., Ganu, Subodh, Festa, Marino, Erickson, Simon J., Straney, Lahn and Schlapbach, Luregn J. (2017). The burden of invasive infections in critically ill indigenous children in Australia. Medical Journal of Australia, 206 (2), 78-84. doi: 10.5694/mja16.00595

Plasma levels of macrophage migration inhibitory factor and d-dopachrome tautomerase show a highly specific profile in early life

Roger, Thierry, Schlapbach, Luregn J., Schneider, Anina, Weier, Manuela, Wellmann, Sven, Marquis, Patrick, Vermijlen, David, Sweep, Fred C. G. J., Leng, Lin, Bucala, Richard, Calandra, Thierry and Giannoni, Eric (2017). Plasma levels of macrophage migration inhibitory factor and d-dopachrome tautomerase show a highly specific profile in early life. Frontiers in Immunology, 8 (JAN) 26, 26. doi: 10.3389/fimmu.2017.00026

Lemierre's syndrome, necrotizing pneumonia and staphylococcal septic shock treated with extracorporeal life support

Mattke, Adrian C., Prabhu, Sudesh, Clark, Julia, Labrom, Robert, Burns, Hanna and Schlapbach, Luregn J. (2017). Lemierre's syndrome, necrotizing pneumonia and staphylococcal septic shock treated with extracorporeal life support. Sage Open Medical Case Reports, 5, 1-5. doi: 10.1177/2050313X17722726

Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition

Morin, Luc, Ray, Samiran, Wilson, Clare, Remy, Solenn, Benissa, Mohamed Rida, Jansen, Nicolaas J. G., Javouhey, Etienne, Peters, Mark J., Kneybar, Martin, De Luca, Daniele, Nadel, Simon, Schlapback, Luregn Jan, Maclaren, Graeme and Tissieres, Pierre (2016). Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition. Intensive Care Medicine, 42 (12), 1-10. doi: 10.1007/s00134-016-4574-2

Corrigendum: exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis

Asgari, Samira, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Kyra A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Lurgen J. and Swiss Pediatric Sepsis Study (2016). Corrigendum: exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in immunology, 7 (OCT) 447, 447. doi: 10.3389/fimmu.2016.00447

Exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis

Asgari, Samari, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Krya A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn, J., Posfay-Barbe, Klara, Giannoni, Eric, Wagner, Benedicht P., Heininger, Ulrich, Konetzny, Gabriel, Donas, Alex, Stocker, Martin, Leone, Antonio, Hasters, Paul, Niederer-Loher, Anita, Kahlert, Christian, Baer, Walter and Relly, Christa (2016). Exome sequencing reveals primary immunodeficiencies in children with community-acquired Pseudomonas aeruginosa sepsis. Frontiers in Immunology, 7 (SEP) 357, 357. doi: 10.3389/fimmu.2016.00357

Burden and outcomes of severe pertussis infection in critically ill infants

Straney, Lahn, Schibler, Andreas, Ganeshalingham, Anusha, Alexander, Janet, Festa, Marino, Slater, Anthony, Maclaren, Graeme and Schlapbach, Luregn J. (2016). Burden and outcomes of severe pertussis infection in critically ill infants. Pediatric Critical Care Medicine, 17 (8), 735-742. doi: 10.1097/PCC.0000000000000851

Procalcitonin in the early course post pediatric cardiac surgery

Zant, Robert, Stocker, Christian, Schlapbach, Luregn Jan, Mayfield, Sara, Karl, Tom and Schibler, Andreas (2016). Procalcitonin in the early course post pediatric cardiac surgery. Pediatric Critical Care Medicine, 17 (7), 624-629. doi: 10.1097/PCC.0000000000000751

Variation in current management of term and late-preterm neonates at risk for early-onset sepsis: an international survey and review of guidelines

van Herk, Wendy, el Helou, Salhab, Janota, Jan, Hagmann, Cornelia, Klingenberg, Claus, Staub, Eveline, Giannoni, Eric, Tissieres, Pierre, Schlapbach, Luregn J., van Rossum, Annemarie M. C., Pilgrim, Sina B. and Stocker, Martin (2016). Variation in current management of term and late-preterm neonates at risk for early-onset sepsis: an international survey and review of guidelines. Pediatric Infectious Disease Journal, 35 (5), 494-500. doi: 10.1097/INF.0000000000001063

Incidence and outcome of Group B streptococcal sepsis in infants in Switzerland

Giannoni, Eric, Berger, Christoph, Stocker, Martin, Agyeman, Philipp, Posfay-Barbe, Klara M., Heininger, Ulrich, Konetzny, Gabriel, Niederer-Loher, Anita, Kahlert, Christian, Donas, Alex, Leone, Antonio, Hasters, Paul, Relly, Christa, Baer, Walter, Aebi, Christoph, Schlapbach, Luregn J. and for the Swiss Pediatric Sepsis Study Group (2016). Incidence and outcome of Group B streptococcal sepsis in infants in Switzerland. Pediatric Infectious Disease Journal, 35 (2), 222-224. doi: 10.1097/INF.0000000000000974

Normal values for pancreatic stone protein in different age groups

Schlapbach, Luregn J., Giannoni, Eric, Wellmann, Sven, Stocker, Martin, Ammann, Roland A. and Graf, Rolf (2015). Normal values for pancreatic stone protein in different age groups. BMC Anesthesiology, 15 (1) 168, 1-6. doi: 10.1186/s12871-015-0149-y

Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS)

Franklin, Donna, Dalziel, Stuart, Schlapbach, Luregn J., Babl, Franz E., Oakley, Ed, Craig, Simon S., Furyk, Jeremy S., Neutze, Jocelyn, Sinn, Kam, Whitty, Jennifer A., Gibbons, Kristen, Fraser, John and Schibler, Andreas (2015). Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS). BMC Pediatrics, 15 (1) 183, 183.1-183.8. doi: 10.1186/s12887-015-0501-x

Five-year survival of children with chronic critical illness in Australia and New Zealand

Namachivayam, Siva P., Alexander, Janet, Slater, Anthony, Millar, Johnny, Erickson, Simon, Tibballs, James, Festa, Marino, Ganu, Subodh, Segedin, Liz, Schlapbach, Luregn J., Williams, Gary, Shann, Frank and Butt, Warwick (2015). Five-year survival of children with chronic critical illness in Australia and New Zealand. Critical care medicine, 43 (9), 1978-1985. doi: 10.1097/CCM.0000000000001076

Trends in PICU admission and survival rates in children in Australia and New Zealand following cardiac arrest

Straney, Lahn D., Schlapbach, Luregn J., Yong, Glenn, Bray, Janet E., Millar, Johnny, Slater, Anthony, Alexander, Janet, Finn, Judith and for the Australian and New Zealand Intensive Care Society Paediatric Study Group (2015). Trends in PICU admission and survival rates in children in Australia and New Zealand following cardiac arrest. Pediatric Critical Care Medicine, 16 (7), 613-620. doi: 10.1097/PCC.0000000000000425

Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study

Schlapbach, Luregn J., Straney, Lahn, Alexander, Janet, MacLaren, Graeme, Festa, Marino, Schibler, Andreas and Slater, Anthony (2015). Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study. The Lancet Infectious Diseases, 15 (1), 46-54. doi: 10.1016/S1473-3099(14)71003-5

Corrigendum to "M-ficolin in children with cancer" [Immunobiology 216, (2011), 633-638] DOI: 10.1016/j.imbio.2010.09.013

Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C. and Ammann, Roland A. (2014). Corrigendum to "M-ficolin in children with cancer" [Immunobiology 216, (2011), 633-638] DOI: 10.1016/j.imbio.2010.09.013. Immunobiology, 219 (12), 990-991. doi: 10.1016/j.imbio.2014.10.024

Restoration of MBL-deficiency: redefining the safety, efficacy and viability of MBL-substitution therapy

Keizer, M. P., Wouters, D., Schlapbach, L. J. and Kuijpers, T. W. (2014). Restoration of MBL-deficiency: redefining the safety, efficacy and viability of MBL-substitution therapy. Molecular Immunology, 61 (2), 174-184. doi: 10.1016/j.molimm.2014.06.005

Intrabronchial Administration of Activated Recombinant Factor VII in a Young Child With Diffuse Alveolar Hemorrhage

Larcombe, P. J., Kapur, N., Fraser, C. J., Coulthard, M. G. and Schlapbach, L. J. (2014). Intrabronchial Administration of Activated Recombinant Factor VII in a Young Child With Diffuse Alveolar Hemorrhage. Pediatric Blood & Cancer, 61 (3), 570-571. doi: 10.1002/pbc.24841

High-flow nasal cannula (HFNC) support in interhospital transport of critically ill children

Schlapbach, Luregn J., Schaefer, Jonas, Brady, Ann-Maree, Mayfield, Sara and Schibler, Andreas (2014). High-flow nasal cannula (HFNC) support in interhospital transport of critically ill children. Intensive Care Medicine, 40 (4), 592-599. doi: 10.1007/s00134-014-3226-7

Enteroviral myocarditis in neonates

Schlapbach, Luregn J., Ersch, Joerg, Balmer, Christian, Pretre, Rene, Tomaske, Maren, Caduff, Rosmarie, Morwood, Jim, Provenzano, Sylvio and Stocker, Christian (2013). Enteroviral myocarditis in neonates. Journal of Paediatrics and Child Health, 49 (9), E451-E454. doi: 10.1111/jpc.12248

Serum concentrations of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the risk of adverse events in pediatric patients with cancer and fever in neutropenia

Amman, Roland A., Bodmer, Nicole, Simon, Arne, Agyeman, Philipp, Leibundgut, Kurt, Schlapbach, Luregn J. and Niggli, Felix K. (2013). Serum concentrations of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the risk of adverse events in pediatric patients with cancer and fever in neutropenia. Journal of the Pediatric Infectious Diseases Society, 2 (2) pit005, 155-161. doi: 10.1093/jpids/pit005

Good agreement between capillary and venous sampling for lectin pathway proteins

Schlapbach, Luregn J., Woerner, Andreas, Thiel, Steffen, Ammann, Roland A., Aebi, Christoph, Nelle, Mathias and Jensenius, Jens C. (2013). Good agreement between capillary and venous sampling for lectin pathway proteins. Immunobiology, 218 (4), 465-469. doi: 10.1016/j.imbio.2012.06.001

Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites

Cestari, Igor, Evans-Osses, Ingrid, Schlapbach, Luregn J., de Messias-Reason, Iara and Ramirez, Marcel I. (2013). Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites. Molecular Immunology, 53 (4), 328-334. doi: 10.1016/j.molimm.2012.08.015

Pancreatic stone protein as a novel marker for neonatal sepsis

Schlapbach, Luregn J., Graf, Rolf, Woerner, Andreas, Fontana, Matteo, Zimmermann-Baer, Urs, Glauser, David, Giannoni, Eric, Roger, Thierry, Muller, Christoph, Nelle, Mathias and Stocker, Martin (2013). Pancreatic stone protein as a novel marker for neonatal sepsis. Intensive Care Medicine, 39 (4), 754-763. doi: 10.1007/s00134-012-2798-3

Extracorporeal membrane oxygenation as a bridge to diagnosis in a 20-month old girl with pulmonary hypertension and right ventricular failure

Schlapbach, Luregn J., Grips, Martin, Justo, Rob and Karl, Tom (2012). Extracorporeal membrane oxygenation as a bridge to diagnosis in a 20-month old girl with pulmonary hypertension and right ventricular failure. Interactive Cardiovascular and Thoracic Surgery, 15 (6), 1088-1089. doi: 10.1093/icvts/ivs401

Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008

Schlapbach, Luregn J., Adams, Mark, Proietti, Elena, Aebischer, Maude, Grunt, Sebastian, Borradori-Tolsa, Cristina, Bickle-Graz, Myriam, Bucher, Hans Ulrich, Latal, Beatrice and Natalucci, Giancarlo (2012). Outcome at two years of age in a Swiss national cohort of extremely preterm infants born between 2000 and 2008. Bmc Pediatrics, 12 (1) 198, 198.1-198.12. doi: 10.1186/1471-2431-12-198

C1-esterase inhibitor treatment in sepsis-Can we target the right patients?

Schlapbach, Luregn J., Schibler, Andreas and Jensenius, Jens C. (2012). C1-esterase inhibitor treatment in sepsis-Can we target the right patients?. Critical Care Medicine, 40 (9), 2735-2736. doi: 10.1097/CCM.0b013e318258eb7a

M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis

Schlapbach, Luregn J., Kjaer, Troels R., Thiel, Steffen, Mattmann, Maika, Nelle, Mathias, Wagner, Bendicht P., Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2012). M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis. Pediatric Research, 71 (4), 368-374. doi: 10.1038/pr.2011.71

Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis

Schlapbach, Luregn J., Thiel, Steffen, Kessler, Ulf, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2011). Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis. Gut, 60 (10), 1438-1439. doi: 10.1136/gut.2010.226027

Umbilical venous concentrations of estradiol in infants with early-onset sepsis and chorioamnionitis

Schlapbach, L. J., Frey, S., Roger, T., Calandra, T., Nelle, M., Aebi, C. and Giannoni, E. (2011). Umbilical venous concentrations of estradiol in infants with early-onset sepsis and chorioamnionitis. Journal of Neonatal-Perinatal Medicine, 4 (2), 147-154. doi: 10.3233/NPM-2011-2739

Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia

Schlapbach, Luregn J., Frey, Stefanie, Bigler, Susanna, Manh-Nhi, Chiem, Aebi, Christoph, Nelle, Mathias and Nuoffer, Jean-Marc (2011). Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia. BMC Pediatrics, 11 (1) 38, 38.1-38.8. doi: 10.1186/1471-2431-11-38

Respiratory symptoms in preterm infants: burden of disease in the first year of life

Pramana, I. A., Latzin, P., Schlapbach, L. J., Hafen, G., Kuehni, C. E., Nelle, M., Riedel, T. and Frey, U. (2011). Respiratory symptoms in preterm infants: burden of disease in the first year of life. European Journal of Medical Research, 16 (5), 223-230. doi: 10.1186/2047-783X-16-5-223

M-ficolin in children with cancer

Schlapbach, Luregn J., Thiel, Steffen, Aebi, Christoph, Hirt, Andreas, Leibundgut, Kurt, Jensenius, Jens C. and Ammann, Roland A. (2011). M-ficolin in children with cancer. Immunobiology, 216 (5), 633-638. doi: 10.1016/j.imbio.2010.09.013

Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer

Fischa, Urs P., Zehndera, Aina, Hirta, Andreas, Nigglib, Felix K., Simonc, Arne, Ozsahind, Hulya, Schlapbacha, Luregn J. and Ammanna, Roland A. (2011). Mannan-binding lectin (MBL) and MBL-associated serine protease-2 in children with cancer. Swiss Medical Weekly, 141 (APRIL), w13191. doi: 10.4414/smw.2011.13191

Human metapneumovirus infection as an emerging pathogen causing acute respiratory distress syndrome

Schlapbach, Luregn Jan, Agyeman, Philipp, Hutter, Damian, Aebi, Christoph, Wagner, Bendicht Peter and Riedel, Thomas (2011). Human metapneumovirus infection as an emerging pathogen causing acute respiratory distress syndrome. Journal of Infectious Diseases, 203 (2), 294-295. doi: 10.1093/infdis/jiq045

Impact of sepsis on neurodevelopmental outcome in a swiss national cohort of extremely premature infants

Schlapbach, Luregn J., Aebischer, Maude, Adams, Mark, Natalucci, Giancarlo, Bonhoeffer, Jan, Latzin, Philipp, Nelle, Mathias, Bucher, Hans Ulrich, Latal, Beatrice, Swiss Neonatal Network and Follow-Up Group, Zeilinger, G., Capone, A., Glanzmann, R., Weber, P., Steinlin, M., Grunt, S., Bar, W., Keller, E., Killer, Ch., Tolsa, J.-F., Bickle-Graz, M., Pfister, R.E., Huppi, P. S., Borradori-Tolsa, C., Berger, T. M., Schmitt-Mechelke, T., Malzacher, A., Micallef, J. P., Steiner, F. and Arlettaz Mieth, R. (2011). Impact of sepsis on neurodevelopmental outcome in a swiss national cohort of extremely premature infants. Pediatrics, 128 (2), E348-E357. doi: 10.1542/peds.2010-3338

Serum Concentrations Of Lectin-Pathway Components In Healthy Neonates, Children And Adults: Mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)

Sallenbach, Seraina, Thiel, Steffen, Aebi, Christoph, Otth, Margrith, Bigler, Susanna, Jensenius, Jens C., Schlapbach, Luregn J. and Ammann, Roland A. (2011). Serum Concentrations Of Lectin-Pathway Components In Healthy Neonates, Children And Adults: Mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2). Pediatric Allergy and Immunology, 22 (4), 424-430. doi: 10.1111/j.1399-3038.2010.01104.x

Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis

Schlapbach, Luregn J., Mattmann, Maika, Thiel, Steffen, Boillat, Colette, Otth, Margrith, Nelle, Mathias, Wagner, Bendicht, Jensenius, Jens C. and Aebi, Christoph (2010). Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis. Clinical Infectious Diseases, 51 (2), 153-162. doi: 10.1086/653531

Author reply

Kessler, Ulf, Zacchariou, Zaccharious, Schlapbach, Luregn J. and Berger, Steffen (2010). Author reply. World Journal of Pediatrics, 6 (2), 185-186. doi: 10.1007/s12519-010-0035-0

Fatal pulmonary embolism in a premature neonate after twin-to-twin transfusion syndrome

Schlapbach, Luregn Jan, Riedel, Thomas, Genitsch, Vera, Nelle, Mathias and McDougall, Felicity Jane (2010). Fatal pulmonary embolism in a premature neonate after twin-to-twin transfusion syndrome. Pediatrics, 126 (2), E483-E487. doi: 10.1542/peds.2009-3490

Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age

Schlapbach, Luregn J., Ersch, Jörg, Adams, Mark, Bernet, Vera, Bucher, Hans Ulrich and Latal, Beatrice (2010). Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age. Acta Paediatrica, International Journal of Paediatrics, 99 (10), 1504-1509. doi: 10.1111/j.1651-2227.2010.01861.x

Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2)

Zehnder, Aina, Fisch, Urs, Hirt, Andreas, Niggli, Felix K., Simon, Arne, Ozsahin, Hulya, Schlapbach, Luregn J. and Ammann, Roland A. (2009). Prognosis in pediatric hematologic malignancies is associated with serum concentration of mannose-binding lectin-associated serine protease-2 (MASP-2). Pediatric Blood and Cancer, 53 (1), 53-57. doi: 10.1002/pbc.22028

Cardiomegaly in a premature neonate after venous umbilical catheterization

Schlapbach, Luregn Jan, Pfammatter, Jean-Pierre, Nelle, Mathias and McDougall, Felicity Jane (2009). Cardiomegaly in a premature neonate after venous umbilical catheterization. European Journal of Pediatrics, 168 (1), 107-109. doi: 10.1007/s00431-008-0704-3

H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients

Schlapbach, L. J., Aebi, C., Hansen, A. G., Hirt, A., Jensenius, J. C. and Ammann, R. A. (2009). H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients. Clinical and Experimental Immunology, 157 (1), 83-89. doi: 10.1111/j.1365-2249.2009.03957.x

M-ficolin in the neonatal period: associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitis

Schlapbach, Luregn J., Kessler, Ulf, Thiel, Steffen, Hansen, Annette G., Nelle, Mathias, Ammann, Roland A., Aebi, Christoph and Jensenius, Jens C. (2009). M-ficolin in the neonatal period: associations with need for mechanical ventilation and mortality in premature infants with necrotising enterocolitis. Molecular Immunology, 46 (13), 2597-2603. doi: 10.1016/j.molimm.2009.05.003

Mannose-binding lectin cord blood levels and respiratory symptoms during infancy: A prospective birth cohort study

Schlapbach, Luregn Jan, Latzin, Philipp, Regamey, Nicolas, Kuehni, Claudia E., Zwahlen, Marcel, Casaulta, Carmen, Aebi, Christoph and Frey, Urs (2009). Mannose-binding lectin cord blood levels and respiratory symptoms during infancy: A prospective birth cohort study. Pediatric Allergy and Immunology, 20 (3), 219-226. doi: 10.1111/j.1399-3038.2008.00782.x

Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis

Schlapbach, Luregn J., Aebi, Christoph, Fisch, Urs, Ammann, Roland A., Otth, Margrith, Bigler, Susanne, Nelle, Mathias, Berger, Steffen and Kessler, Ulf (2008). Higher cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis. Pediatric Research, 64 (5), 562-566. doi: 10.1203/PDR.0b013e3181841335

Floppy infant with macrocytic anemia and vegan mother

Schlapbach L.J., Schutz B., Nuoffer J.-M., Brekenfeld C., Muller G. and Fluri S. (2007). Floppy infant with macrocytic anemia and vegan mother. Praxis, 96 (35), 1309-1314. doi: 10.1024/1661-8157.96.35.1309

Serum levels of mannose-binding lectin and the risk of fever in neutropenic pediatric cancer patients

Schlapbach, L. J., Aebi, C., Otth, M., Luethy, A. Ridolfi, Leibundgut K., Hirt A. and Ammann R.A. (2007). Serum levels of mannose-binding lectin and the risk of fever in neutropenic pediatric cancer patients. Pediatric Blood and Cancer, 49 (1), 11-16. doi: 10.1002/pbc.21097

Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients

Schlapbach L.J., Aebi C., Otth M., Leibundgut K., Hirt A. and Ammann R.A. (2007). Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients. Pediatric Infectious Disease Journal, 26 (11), 989-994. doi: 10.1097/INF.0b013e31811ffe6a

A small child with acute abdomen and iron deficiency anemia

Schlapbach L., Liniger B., Schibli S. and Cholewa D. (2006). A small child with acute abdomen and iron deficiency anemia. Praxis, 95 (22), 913-916. doi: 10.1024/0369-8394.95.22.913

Severe normotensive metabolic alkalosis in a 2-month-old boy with hyperekplexia

Schlapbach L.J., Sozzo A., Ramelli G. and Bianchetti M.G. (2006). Severe normotensive metabolic alkalosis in a 2-month-old boy with hyperekplexia. Journal of Inherited Metabolic Disease, 29 (1), 238-239. doi: 10.1007/s10545-006-0082-9

Association of a pool of HIV-1 with erythrocytes in vivo: A cohort study

Hess C., Klimkait T., Schlapbach L., Del Zenero V., Sadallah S., Horakova E., Balestra G., Werder V., Schaefer C., Battegay M. and Schifferli J.-A. (2002). Association of a pool of HIV-1 with erythrocytes in vivo: A cohort study. Lancet, 359 (9325), 2230-2234. doi: 10.1016/S0140-6736(02)09291-7

Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department

Gilholm, P., Irwin, A., Lister, P., Harley, A., Raman, S., Schlapbach, L. J. and Gibbons, K. (2022). Identifying clinical symptom profiles for sepsis in children screened for sepsis on admission to the emergency department. 11th Congress of the World Federation of Pediatric Intensive & Critical Care Societies, Online, 12-16 July 2022. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000899876.46317.ec

Time for Sepsis-3 in kids? - Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection

Schlapbach, L. (2018). Time for Sepsis-3 in kids? - Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.026

Time for Sepsis-3 in kids? Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection

Schlapbach, L. (2018). Time for Sepsis-3 in kids? Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qS0FA in children with infection. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.aucc.2017.12.005

Burden of disease and change in practice in critically ill infants with bronchiolitis in Australia and New Zealand 2002 to 2014

Schlapbach, Luregn, Straney, Lahn, Gelbart, Ben, Alexander, Janet, Franklin, Donna, Beca, John, Whitty, Jennifer, Ganu, Subodh, Wilkins, Barry, Slater, Anthony, Croston, Elizabeth, Erickson, Simon and Schibler, Andreas (2017). Burden of disease and change in practice in critically ill infants with bronchiolitis in Australia and New Zealand 2002 to 2014. 41st Australian and New Zealand Scientific Meeting on Intensive Care, Perth WA, Australia, 20-22 October 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2017.02.067

Burden of Disease and Change in Practice in Critically Ill Infants with Bronchiolitis in Australia and New Zealand 2002 to 2014

Schlapbach, L. J., Straney, L., Gelbart, B., Alexander, J., Franklin, D., Beca, J., Whitty, J. A., Ganu, S., Wilkins, B., Croston, E., Erickson, S. and Schibler, A. (2016). Burden of Disease and Change in Practice in Critically Ill Infants with Bronchiolitis in Australia and New Zealand 2002 to 2014. NEW YORK: SPRINGER. doi: 10.1016/j.aucc.2017.02.067

Severe Sepsis with Bacteremia in Children in Switzerland - Results From the Swiss Pediatric Sepsis Study

Schlapbach, L. J., Agyeman, P., Giannoni, E., Stocker, M., Posfay-Barbe, K., Heiningere, U., Schindler, M., Kuehni, C., Konetzny, G., Niederer-Loher, A., Kahlert, C., Hasters, P., Relly, C., Baer, W., Aebi, C. and Berger, C. (2016). Severe Sepsis with Bacteremia in Children in Switzerland - Results From the Swiss Pediatric Sepsis Study. NEW YORK: SPRINGER.

Pancreatic stone protein as a novel marker for neonatal sepsis

Schlapbach, L, Graf, R., Woerner, A., Nelle, M., Stocker, M., Fontana, M., Zimmermann-Baer, U., Glauser, D., Giannoni, E., Roger, T. and Mueller, C. (2012). Pancreatic stone protein as a novel marker for neonatal sepsis. Sepsis 2012, Paris, France, 7-9 November 2012. Springer Nature. doi: 10.1186/cc11765

Age-specific normal ranges of lectin-pathway components in human serum: mannose-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2).

Sallenbach, S., Thiel. S., Aebi, C., Otth, M., Jensenius, J. C., Schlapbach, L. J. and Ammann, R. A. (2011). Age-specific normal ranges of lectin-pathway components in human serum: mannose-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2).. 23rd International National Complement Workshop, New York, New York, USA, 01-05 August 2010. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2010.05.069

M-ficolin serum concentrations are related to early-onset neonatal sepsis and circulating phagocytes

Schlapbach, L. J., Thiel, S., Mattmann, M., Nelle, M., Wagner, B., Ammann, R. A., Aebi, C. and Jensenius, J. C. (2010). M-ficolin serum concentrations are related to early-onset neonatal sepsis and circulating phagocytes. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.031

Serum M-ficolin in children with cancer

Schlapbach, L. J., Thiel, S., Aebi, C., Hirt, A., Leibundgut, K., Jensenius, J. C. and Ammann, R. A. (2010). Serum M-ficolin in children with cancer. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.241

Elevated cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis - a case-control study

Schlapbach, L. J., Aebi, C., Nelle, M., Ammann, R. A., Berger, S. and Kessler, U. (2008). Elevated cord blood levels of mannose-binding lectin-associated serine protease-2 in infants with necrotising enterocolitis - a case-control study. E M H SWISS MEDICAL PUBLISHERS LTD.

Serum concentration of H-ficolin and the risk of fever and neutropenia in pediatric cancer patients

Schlapbach, L. J., Ammann, R. A., Hansen, A. Gudmann, Hirt, A., Jensenius, J. C. and Aebi, C. (2008). Serum concentration of H-ficolin and the risk of fever and neutropenia in pediatric cancer patients. E M H SWISS MEDICAL PUBLISHERS LTD.

Mannose-binding Lectin cord blood levels are associated with respiratory symptoms during infancy

Schlapbach, L. J., Latzin, P., Regamey, N., Kuehni, C. E., Zwahlen, M., Casaulta, C., Aebi, C. and Frey, U. (2007). Mannose-binding Lectin cord blood levels are associated with respiratory symptoms during infancy. E M H SWISS MEDICAL PUBLISHERS LTD.

Severe infections in critically ill children – from epidemiology to outcome prediction

Schlapbach Tribolet, Luregn (2020). Severe infections in critically ill children – from epidemiology to outcome prediction. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2020.190