Dr Zachary Houston

Postdoctoral Research Fellow

Centre for Advanced Imaging

Overview

Zach obtained his PhD in Chemistry from the International Institute for Nano and Molecular Medicine at the University of Missouri in 2014 under the supervision of Professor M. Frederick Hawthorne. He joined the Centre for Advanced Imaging and the Australian Institute for Bioengineering and Nanotechnology at the University of Queensland as a Postdoctoral Fellow in Associate Professor Kristofer Thurecht’s lab in 2014, and has applied his expertise in organic chemistry and synthetic design to develop novel nanomaterials towards the assessment and treatment of disease states using molecular imaging. Through the combination of bioorthogonal and responsive systems with a range of multimodal in vivo imaging techniques, Zach’s main research aims have been focused on understanding how nanomaterials interact with biological environments and how that information can be used to enhance the efficiency of those nanomaterials.

Qualifications

  • PhD Chemistry, University of Missouri

Publications

  • Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019) Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 6: . doi:10.3390/ijms20061280

  • Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019) Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies. Advanced Healthcare Materials, e1801607. doi:10.1002/adhm.201801607

  • Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D. and Parekh, Harendra S. (2019) Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics, 136 102-107. doi:10.1016/j.ejpb.2019.01.014

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2018). Hyperbranched polymers as nanocarriers. In Encyclopedia of polymer science and technology (pp. 1-27) Hoboken, NJ USA: John Wiley & Sons. doi:10.1002/0471440264.pst159.pub2

Journal Article

Conference Publication

  • Lilja, Andrew R., Strong, Campbell W., Bailey, Benjamin J., Thurecht, Kristofer J., Houston, Zachary H., Fletcher, Nicholas L. and McGhee, John B. (2018). Design-led 3D visualization of nanomedicines in virtual reality. In: Spencer, S. N., Proceedings - VRST 2018: 24th ACM Symposium on Virtual Reality Software and Technology. 24th ACM Symposium on Virtual Reality Software and Technology (ACM VRST), Tokyo, Japan, (). Nov 28- Dec 01 2018. doi:10.1145/3281505.3281572

  • Thurecht, Kristofer, Zhou, Yongmei, Fletcher, Nicholas and Houston, Zachary (2018). Development of polymer theranostics to probe the behaviour of nanomaterials in biology. In: 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, (). 18-22 March 2018.

  • Thurecht, Kristofer, Fuchs, Adrian, Bapat, Abhijeet and Houston, Zachary (2018). Development of polymeric MRI agents as theranostics. In: 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA United States, (). 18-22 March 2018.

  • Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. In: 10th World Biomaterials Congress, Montréal, Canada, (). 17 May - 22 May 2016. doi:10.3389/conf.FBIOE.2016.01.02237

  • Houston, Z., Ghosh, T. K. and Prelas, M. A. (2005). Use of hydrogen plasma for storing hydrogen in nanophase diamond powder. In: Transactions of the American Nuclear Society - 2005 Annual Meeting. 2005 Annual Meeting - American Nuclear Society, San Diego, CA, United States, (88-89). 5-9 June 2005.

PhD and MPhil Supervision

Current Supervision