Dr Nedeljka Rosic

Adjunct Fellow

School of Biological Sciences
Faculty of Science

Overview

I grew up in Serbia and start thinking about Science due to my love for genetics. I received a BSc (Hons First Class) in Molecular Biology and Physiology and a MSc in Plant Biology from the University of Belgrade. After moving to Brisbane, I completed a PhD in Biomedical Sciences at the University of Queensland. I have been awarded with a UQ Postdoctoral Fellowship for Women (2011-2013) and a prestigious Discovery Early Career Researcher Award by ARC (2012-2014).

Research Interests

  • Reprogramming Symbiodinium epigenome for higher temperature conditions
    The goal of this project is to enhance our understanding of the capacity of coral algae to tolerate thermal stress using an ancient epigenetic mechanism DNA methylation for reprogramming their epigenomes.
  • Algae as a source of UV-absorbing compounds
    Exposure to ultraviolet radiation especially when combined with thermal stress, has been recognized as an important abiotic factor leading to oxidative stress and break down of the coral-algal endosymbiosis. In nature, many marine organisms use Mycosporine-like Amino Acids (MAAs) as biological sunscreens in UV protection and the prevention of oxidative stress.
  • Transcriptomics for detection of stress in coral
    Our results will provide new insights into the transcriptional profiles of the coral holobiont and transcriptional regulation prior bleaching. In addition, we will identify a range of potential stress biomarkers that could be used for the development of the early warning signs of stress in reef-building corals.

Research Impacts

My research focuses on:

1. Understanding the regulatory mechanisms and the biosynthesis of bioactive compounds (e.g. marine sunscreens)

2. Genetics/genomics of cellular stress

3. Host-microbe symbiosis

Qualifications

  • Doctor of Philosophy, The University of Queensland

Publications

  • de Mendoza, Alex, Bonnet, Amandine, Vargas-Landin, Dulce B, Ji, Nanjing, Hong, Fei, Yang, Feng, Li, Ling, Hori, Koichi, Pflueger, Jahnvi, Buckberry, Sam, Ohta, Hiroyuki, Rosic, Nedeljka, Lesage, Pascale, Lin, Senjie and Lister, Ryan (2018) Recurrent acquisition of cytosine methyltransferases into eukaryotic retrotransposons. Nature Communications, 9 1: 1341. doi:10.1038/s41467-018-03724-9

  • Kaniewska, Paulina, Chan, Chon-Kit Kenneth, Kline, David, Ling, Edmund Yew Siang, Rosic, Nedeljka, Edwards, David, Hoegh-Guldberg, Ove and Dove, Sophie (2015) Transcriptomic changes in coral holobionts provide insights into physiological challenges of future climate and ocean change. PLoS One, 10 10: 1-30. doi:10.1371/journal.pone.0139223

  • ReFuGe 2020 Consortium, Voolstra, Christian R, Miller, David J., Ragan, Mark A., Hoffmann, Ary A., Hoegh-Guldberg, Ove, Bourne, David G., Ball, Eldon E., Ying, Hua, Forêt, Sylvain, Takahashi, Shunichi, Weynberg, Karen D., van Oppen, Madeleine J. H., Morrow, Kathleen, Chan, Cheong Xin, Rosic, Nedeljka, Leggat, William, Sprungala, Susanne, Imelfort, Michael, Tyson, Gene W., Kassahn, Karin S., Lundgren, Petra B., Beeden, Roger J., Ravasi, Timothy, Berumen, Michael L., Abal, Eva and Fyffe, Theresa (2015) The ReFuGe 2020 Consortium—using “omics” approaches to explore the adaptability and resilience of coral holobionts to environmental change. Frontiers in Marine Science, 2 Art No.: 68: . doi:10.3389/fmars.2015.00068

View all Publications

Publications

Book Chapter

  • Rosic, Nedeljka N., Braun, Christoph and Kvaskoff, David (2015). Extraction and analysis of mycosporine-like amino acids in marine algae. In Dagmar B. Stengel and Solène Connan (Ed.), Natural products from marine algae (pp. 119-129) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-2684-8_6

  • Rosic, Nela (2013). DNA shuffling of cytochromes P450 for indigoid pigment production. In Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano (Ed.), Cytochrome P450 protocols 3rd ed. (pp. 205-224) New York, NY, United States: Humana Press. doi:10.1007/978-1-62703-321-3_18

Journal Article

Conference Publication

  • Rosic, N. and Dove, S. (2013). How can dinoflagellates help in reducing coral reef vulnerability to environmental stress?. In: M. Dennis Hanisak, James A. Nienow and Akshinthala K. S. K. Prasad, Abstracts of Papers to be Presented at the 10th International Phycological Congress. 10th International Phycological Congress, Orlando, Florida, United States, (94-94). 4-10 August 2013.

  • Rosic, Nela, Pernice, Mathieu, Hoegh-Guldberg, Ove and Dove, Sophie (2011). Differential Regulation of Heat Shock Proteins and Cytochrome P450 Genes in Symbiotic Dinoflagellates Under Thermal Stress. In: Fifth European Phycological Congress: EPC5 Programme and Abstracts. 5th European Phycological Congress, Rhodes, Greece, (145-145). 04-09 September 2011. doi:10.1080/09670262.2011.613192

  • Rosic, Nela, Kaniewska, Pauline, Ling, Edmund, Edwards, David, Dove, Sophie and Hoegh-Guldberg, Ove (2011). Transcriptomics of the coral-algal symbiosis in response to environmental stress. In: Fifth European Phycological Congress: EPC5 Programme and Abstracts. 5th European Phycological Congress, Rhodes, Greece, (97-97). 04-09 September 2011. doi:10.1080/09670262.2011.613190

  • Rosic, Nedeljka, Lonhienne, Thierry G.A., DeVoss, James J. and Gillam, Elizabeth M.J. (2003). Directed evolution of mammalian cytochrome P450 enzymes involved in xenobiotic metabolism. In: Drug Metabolism Reviews: Proceedings 8th European Meeting of the International-Society-for-the-Study-of-Xenobiotics (ISSX). 8th European Meeting of the International-Society-for-the-Study-of-Xenobiotics (ISSX), Dijon, France, (46-46). 27 April - 1 May, 2003. doi:10.1081/DMR-120020120