Associate Professor Graeme Macdonald

Academic Title-Associate Professor

Princess Alexandra Hospital Southside Clinical Unit
Faculty of Medicine
g.macdonald@uq.edu.au
+61 7 3176 2613

Overview

Qualifications

  • PhD, The University of Queensland
  • MBBS, The University of Queensland
  • FRACP

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Master Philosophy

View all Supervision

Publications

Book Chapter

  • Hickman, Ingrid J., Macdonald, Graeme A. and Byrne, Nuala M. (2013). Physical activity and cardiovascular fitness in patients with NAFLD: Clinical importance and therapeutic implications. In Non-alcoholic fatty liver disease : A practical guide (pp. 132-148) Chichester, W Sussex, U,K.: Wiley-Blackwell. doi:10.1002/9781118556153.ch12

  • Macdonald, Graeme A. (2008). Suspected iron overload or high serum ferritin. In Nicholas J. Talley, Isidor Segal and Martin D. Weltman (Ed.), Gastroenterology and Hepatology: A clinical handbook (pp. 389-396) Marrickville, N.S.W.: Elsevier Australia.

  • Macdonald, G. (2001). Pathogenesis of hepatocellular carcinoma. In No editors (Ed.), Clinics in Liver Disease Vol 5, No.1 ed. (pp. 69-86) Philadelphia, Pennsylvania: W. Saunders.

  • Conrad, S., Dunne, M. and Macdonald, G. (2001). Quality of Life. In Nick Crofts, Greg Dore and Stephen Locarnini (Ed.), Hepatitis C: An Australian Perspective 1 ed. (pp. 185-193) Melbourne: IP Communications.

Journal Article

Conference Publication

  • Croci, Ilaria, Hickman, Ingrid J., Wood, Rachel E., Borrani, Fabio, Macdonald, Graeme A. and Byrne, Nuala M. (2014). Fat oxidation over a range of exercise intensities: fitness versus fatness. In: Conference Proceedings: 6th Exercise and Sports Science Australia Conference and Sports Dietitians Australia Update: Research to Practice. 6th Exercise and Sport Science Australia Conference, Adelaide, SA, Australia, (50-50). 10-12 April 2014.

  • Kendall, B. J., Macdonald, G. A., Prins, J. B., O'Brien, S. and Whiteman, D. C. (2013). Abdominal obesity and Barrett's oesophagus - does hip obesity reduce the risk?. In: Australian Gastroenterology Week 2013, Melbourne Australia, (127-127). 7-9 October 2013. doi:10.1111/jgh.12365_7

  • Strasser, S. I., Roberts, S. K., Gane, E. J., Macdonald, G. A., Thompson, A. J., Weltman, M. D., Weilert, F., Hill, A., Laeuffer, J. and Dore, G. J. (2013). Management and outcomes of side effects with focus on anaemia in patients with hepatitis c genotype 1 infection: The telaprevir early access program in patients from Australia and New Zealand. In: Special Issue: Abstracts of the Australian Gastroenterology Week 2013. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, (168-169). 7 - 9 October 2013. doi:10.1111/jgh.12365_14

  • Raj, A. S., Macdonald, G. A., Bhat, P., Fletcher, L. M., Tran, C., Black, M. and Holtmann, G. (2013). Significant hepatic fibrosis is associated with increased small intestinal permeability. In: Special Issue: Abstracts of the Australian Gastroenterology Week 2013. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, (55-55). 7 - 9 October 2013. doi:10.1111/jgh.12365_5

  • Macdonald, G. A., Roberts, S. K., Dore, G. J., Gane, E. J., Thompson, A. J., Weltman, M. D., Weilert, F., Hill, A., Laeuffer, J. and Strasser, S. I. (2013). Treatment of hepatitis c genotype 1 patients with severe fibrosis or compensated cirrhosis: The telaprevir early access program in patients from Australia and New Zealand. In: Special Issue: Abstracts of the Australian Gastroenterology Week 2013. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, (169-169). 7 - 9 October 2013. doi:10.1111/jgh.12365_14

  • Forgan-Smith, K. R., Stuart, K. A., Tallis, C., Macdonald, G. A. and Fawcett, J. (2013). Trends in treatment of recurrent hepatitis C after liver transplantation. In: Special Issue: Abstracts of the Australian Gastroenterology Week 2013. The Australian Gastroenterology Week 2013, Melbourne, VIC Australia, (174-175). 7 - 9 October 2013. doi:10.1111/jgh.12365_14

  • Hickman, I., Byrne, N., Croci, I., Elisabetta, B., Clouston, A., Chachay, V., Buzzigoli, E., Hills, A., Gastaldelli, A., O'Moore Sullivan, T., Prins, J. and Macdonald, G. (2012). The independent effect of exercise on the metabolic and histological features of non-alcoholic fatty liver disease. In: 19th European Congress on Obesity (ECO2012): Abstracts. 19th European Congress on Obesity (ECO2012), Lion, France, (26-26). 9-12 May 2012. doi:10.1159/000171026

  • Heritage, Mandy, Jaskowski, Lesley, Wilkinson, Ashley S., Britton, Laurence, Tan, Terrence C., Clouston, Andrew D., Bridle, Kim, Anderson, Gregory J., Macdonald, Graeme A., Fletcher, Linda M., Subramaniam, V. Nathan and Crawford, Darrell H. (2012). The progression of NAFLD to NASH in a mouse model of Hfe(-/-)- associated steatohepatitis is attenuated by co-administration of curcumin and vitamin E. In: Abstracts of the 63rd Annual Meeting of the American Association for the Study of Liver Diseases. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston MA., United States, (873A-873A). 9-13 November 2012. doi:10.1002/hep.26040

  • Kendall, B. J., MacDonald, G. A., Hayward, N. K., Prins, J. B., O'Brien, S., Whiteman, D. C. and for the Study of Digestive Health (2010). Daytime sleepiness, gastro-oesophageal reflux and Barrett's oesophagus: A case-control study. In: Australian Gastroenterology Week 2010, Broadbeach, Qld., Australia, (A41-A41). 20-23 October 2010. doi:10.1111/j.1440-1746.2010.06451.x

  • Kendall, B. J., Macdonald, G. A., Hayward, N. K., Prins, J. B., O'Brien, S., Whiteman, D. C. and for the Study of Digestive Health (2010). Metabolic syndrome and the risk of Barrett's oesophagus. In: Australian Gastroenterology Week 2010, Broadbeach, Qld., Australia, (A78-A78). 20-23 October 2010. doi:10.1111/j.1440-1746.2010.06453.x

  • Daveson, A. J. M., Jones, D., Mcsorley, H., Gaze, S., Mccarthy, J., Clouston, A., Pascoe, A., Macdonald, G., Speare, R., Anderson, R., Loukas, A and Croese, J. (2009). A phase 2A randomized double blinded placebo controlled study evaluating immunity and gluten sensitivity by inoculating coeliac disease patients with the human hookworm necator americanus. In: Journal of Gastroenterology and Hepatology: Abstracts of the Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009. The Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney Convention & Exhibition Centre, Sydney, NSW, (A221-A222). 21-24 October 2009. doi:10.1111/j.1440-1746.2009.06050.x

  • Nguyen, T. V., Murphy, T. L., Lipka, G., Fletcher, L. M. and MacDonald, G. A. (2009). High molecular weight adiponectin is reduced in non alcoholic fatty liver disease. In: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney, Australia, (A286-A287). 21-24 October 2009.

  • Bowser, N., Murray, E., Ho, V., Ali, A. and Macdonald, G. (2009). Pre-liver transplant micronutrient status and impact on post-liver transplant outcomes. In: Journal of Gastroenterology and Hepatology: Abstracts of the Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009. The Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney Convention & Exhibition Centre, Sydney, NSW, (A296-A296). 21-24 October 2009. doi:10.1111/j.1440-1746.2009.06055.x

  • Kendall, B. J., MacDonald, G. A., Hayward, N. K., Green, A. C., Webb, P. M. and Whiteman, D. C. (2009). Undiagnosed coeliac disease and risk of oesophageal squamous cell carcinoma. In: Abstracts of the Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009. The Australia & New Zealand Medical & Surgical Gastrointestinal Week 2009, Sydney, Australia, (A339-A339). 21-24 October 2009. doi:10.1111/j.1440-1746.2009.06061.x

  • Hickman, I. J., Sullivan, C. M., Flight, S., Campbell, C., Crawford, D. H., Masci, P. P., O'Moore-Sullivan, T. M., Prins, J. B. and Macdonald, G. A. (2008). Obesity is linked with increased clot strength and impaired fibrinolysis in nonalcoholic fatty liver disease. In: International Journal Of Obesity. 16th European Congress on Obesity, Geneva, Switzerland, (S59-S59). 14-17 May 2008.

  • Nguyen, Thien, Murphy, Therese L., Lipka, Geraldine, Fletcher, Linda M. and Macdonald, Graeme A. (2008). The ratio of high molecular weight (HMW) to total adiponectin correlates with insulin resistance in fatty liver disease. In: Hepatology. The Liver Meeting 2008: 59th Annual Meeting of the American Association for the Study of Liver Diseases. The Liver Meeting 2008: 59th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, (848A-848A). 31 October-4 November 2008. doi:10.1002/hep.22645

  • Martin, J., Ferndale, C., Hayllar, J., Lambert, S., McGrath, F., Page, A., Reiner, R., Reuter, B., Sexton, J., White, S., Wittmann, J. and Macdonald, G. (2008). What do GPS in QLD really think about community based HCV prescribing?. In: Journal of Gastroenterology and Hepatology. Abstracts of the 6th Australasian Viral Hepatitis Conference. 6th Australasian Viral Hepatitis Conference, Brisbane, Queensland, Australia, (A352-A352). 20–22 October 2008. doi:10.1111/j.1440-1746.2008.05655_2.x

  • Sharman, J. E., Holland, D., Kostner, K., Fairweather, H., Macdonald G. and Marwick T. H. (2007). The association between viscosity and cardiovascular risk may reflect the central systolic stress response to light activity: an exercise haemodynamic study. In: J. Richmond, Heart, Lung and Circulation: Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Cardiac Society of Aust and NZ Annual Scientific Meeting, Christchurch, New Zealand, (S169-S169). 9-12 August, 2007. doi:10.1016/j.hlc.2007.06.420

  • Sharman, J., Holland, D., Kostner, K. M., Fairweather, H., Macdonald, G. A. and Marwick, T. H. (2007). The association between viscosity and cardiovascular risk may reflect the central systolic stress response to light activity: an exercise hemodynamic study. In: F. Van de Werf, European Heart Journal. European Society of Cardiology Annual Scientific Meeting, Vienna, Austria, (S244-S244). 1-5 September, 2007.

  • Bridle, K. R., Murphy, T. L., Anderson, G. J., Macdonald, G. A., Crawford, D. H. G. and Fletcher, L. M. (2006). Serum adiponectin is increased in HFE-/- mice fed alcohol. In: Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week 2006, Adelaide, South Australia, (A323-A323). 11-14 October, 2006. doi:10.1111/j.1440-1746.2006.04689.x

  • Anderson, Greg, Frazer, David M., Bridle, Kim R., Macdonald, Graeme A., Smith, Jeffrey L., Turlin, Bruno, Subramaniam, Nathan, Crawford, Darrell H., Powell, Lawrie W. and Ramm, Grant A. (2005). Expression of the iron regulatory peptide hepcidin is reduced in patients with chronic liver disease. In: Blood. 47th Annual Meeting of the American Society of Hematology, Atlanta, Georgia, USA, (1001A-1001A). 10-13 December, 2005.

  • Stephenson, M. D., Bridle, K. R., Whitehead, J. P. and Macdonald, G. A. (2005). Optimising conditions for assessing glucose output from isolated rat hepatocytes in response to insulin. In: Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week 2005, Brisbane, Qld, Australia, (A77-A77). 19-22 October, 2005. doi:10.1111/j.1440-1746.2005.04091_4.x

  • Hickman, Ingrid J., Prins, Johannes B., Whitehead, Jonathon P. and Macdonald, Graeme A. (2005). Presence of the metabolic syndrome is associated with reduced adiponectin levels and liver dysfunction in patients with type 2 diabetes. In: Hepatology: Abstracts of the 56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases,. 56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases,, San Francisco, CA, (612A-613A). 11-15 November, 2005. doi:10.1002/hep.20927

  • Lang, C. A., Battistutta, D., Garrett, L. E., Cooksley, W. G. E., Dunne, M. P. and Macdonald, G. A. (2004). Impairments in quality of life due to symptom clusters in people living with chronic hepatitis C infection are poorly identified by the Short Form-36 (SF-36). In: Hepatology: Abstracts from the 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, Massachusetts, (514A-514A). 29 October - 2 November, 2004.

  • Lang, C. A., Battistutta, D., Garrett, L. E., Cooksley, W. G. E., Dunne, M. P. and Macdonald, G. A. (2004). Symptom prevalence and temporal clustering of symptoms in people living with chronic hepatitis C infection. In: Journal of Hepatology: Abstracts from the 39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver. 39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Berlin, Germany, (143-143). 14-18 April, 2004. doi:10.1016/S0168-8278(04)90485-0

  • Richards, Ayanthi, Prins, John B., Whitehead, Jon and MacDonald, Graeme A. (2004). The site and role of post-translational modifications in the oligiomerisation and secretion of adiponectin. In: Hepatology: Abstracts from the 55th Annual Meeting of the American Association for the Study of Liver Diseases. 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, Massachusetts, (526A-526A). 29 October - 2 November, 2004.

  • Herath, N., Walsh, M., Kew, M., Young, J., Leggett, B. and Macdonald, G. A. (2002). E-cadherin and beta-catenin do not appear to be involved in hepatocarcinogenesis in Australia and South Africa. In: Hepatology: Abstracts from the 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD). 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, Massachusetts, (447A-447A). 1-5 November, 2002.

  • Macdonald, G. A., Lang, C., Garrett, L., Cook, M., Williams, H., Cooksley, G. and Dunne, M. P. (2002). Quality of life in hepatitis C infection: A profile of symptoms. In: Hepatology: Abstracts from the 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD). 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, Massachusetts, (560A-560A). 1-5 November, 2002.

  • Hickman, Ingrid, Clouston, Andrew, Ash, Susan, MacDonald, Graeme, Jonsson, Julie and Powell, Elizabeth (2002). Weight reduction improves biochemistry and histology in patients with chronic hepatitis C. In: American Journal of Clinical Nutrition: Abstracts from Nutrition Week: A Scientific and Clinical Forum and Exposition. Nutrition Week: A Scientific and Clinical Forum and Exposition, Bethesda, MD, (339S-339S). 2002.

  • Hickman, Ingrid, Clouston, Andrew, Macdonald, Graeme, Ash, Susan, Prins, John, Purdie, David, Jonsson, Julie and Powell, Elizabeth (2002). Weight reduction in patients with chronic HCV reduces circulating insulin levels. In: Journal of Hepatology. -, Milan, Italy, (255-256). April 18th, 2002. doi:10.1016/S0168-8278(02)80921-7

  • Hickman, I., Jonsson, J. R., Clouston, A., Macdonald, G. and Powell, E. (2001). Maintenance of weight reduction after successful nutritional intervention in patients with fatty liver disease. In: Journal of Gastroenterology & Hepatology. Asia Pacific Digestive Week 2001, Sydney, Australia, (A74-A74). 23-27 Sep, 2001.

  • Butterworth, L. A., Cooksley, W. G. E., Crawford, D., D'Arcy, D., Dorrington, L., Garrett, L., Hourigan, K., Macdonald, G. and Walker, D. (2000). Early detection of response to interferon treatment in chronic HCV. In: 10th International Symposium on Viral Hepatitis and Liver Disease. 10th Int Symp on Viral Hepatitis and Liver Disease, Atlanta, USA, (). 9-13 April, 2000.

  • Cooksley, W. G. E., Crawford, D., Gowans, E. J., Harrison, M., Lott, W. B., Macdonald, G. and Sloots, T. (2000). Effects of cobalamin on hepatitis C virus translation and replication. In: Annual Mtg of the American Association for the Study of Liver Disease. Ann Mtg of American Assn for the Study of Liver Disease, Dallas, Texas, ((abstract)). 27-31 Oct, 2000.

  • Wright, C.M., Dent, O. F., Barker, M.A., Newland, R. C., Chapuis, P. H., Bokey, E. L., Young, J. P., Leggett, B. A., Jass, J. R. and Macdonald, G. (2000). The "highs" and "lows" of microsatellite instability in sporadic ACPS C colorectal cancer - improving prognostic stratification for this group of patients. In: Journal of Gastroenterology & Hepatology. Australian Gastroenterology Week 2000, Hobart, (J91). 18-21 Oct, 2000.

  • Mortimore, M, Francis, LP, Purdie, DM, Edwards, JT, Pandeya, N, Searle, J, Cooksley, G, Powell, LW and MacDonald, GA (2000). The relationship between hepatic steatosis and indices of obesity. In: Abstracts of the 51st Annual Meeting of the American Association for the Study of Liver Disease. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, Texas, (417A-417A). 27-31 Oct, 2000.

  • Clouston, A. D., Jonsson, J. R., Shorthouse, C., Mori, T., Prins, J., Macdonald, G. and Powell, E. E. (2000). Weight reduction in patients with chronic hepatitis improves liver histology and biochemistry. In: Abstracts of the 51st Annual Meeting American Association for the Study of Liver Disease. 51st Annual Meeting American Association for the Study of Liver Disease, Dallas, TX, United States, (308A-308A). 27 - 31 October 2000.

  • Higgins, C., Clouston, A. D., Strong, R. W. and Macdonald, G. A. (1999). Clinicopathological analysis of hepatocellular carcinoma arising in non-cirrhotic liver. In: Hepatology. American Association for the Study of Liver Diseases, Dallas, USA, (280A). 5-9 Nov, 1999.

  • Higgins, C. M., Clouston, A. D., Strong, R. W. and Macdonald, G. A. (1999). Clinicopathological analysis of hepatocellular carcinoma occuring in non-cirrhotic patients. In: Journal of Gastroenterology and Hepatology: Abstracts of the Australian Gastroenterology Week 1999. Australian Gastroenterology Week 1999, Brisbane Convention Centre, (A201-A201). 4-8 October, 1999.

  • Biden, K. G., Wright, C.M., Simms, L. A., Macdonald, G. A., Jass, J. R., Young, J. P. and Leggett, B. A. (1999). Early divergence of the DNA mismatch repair deficient pathway in colorectal tumorigenesis. In: Leeds Castle Polyposis Group and INternational Collaborative Group for Hereditary Non-Polyposis Colorectal Cancer. From Genes to the Clinic & Beyond. Understanding & Managing Bowel Cancer, Melbourne & Lorne, (24). 1-6 March, 1999.

  • Wright, C.M., Whitehall, V. L., Dent, O. F., Walsh, M. D., Searle, J., Newland, R. C., Chapuis, P. H., Jass, J. R., Young, J. P., Leggett, B. A. and Macdonald, G. (1999). Improved survival in stage C colorectal cancers exhibiting microsatellite instability. In: Leeds Castle Polyposis Group and International Collaborative Group for Hereditary Non-Polyposis Colorectal Cancer. From Genes to the Clinic & Beyond. Understanding & Managing Bowel Cancer, Melbourne & Lorne, (23). 1 - 6 March 1999.

  • Herath, N., Kew, M. C., Young, J., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Loss of heterozygosity at 4q in hepatocellular carcinoma is more common in patients with hepatitis B infection. In: Royal Brisbane Hospital Health Care Symposium. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, (57). 21 - 27 Oct, 1999.

  • Higgins, C., Clouston, A. D., Strong, R. W. and Macdonald, G. A. (1999). The clinico-pathological features of hepatocellular carcinoma occuring in non-cirrhotic patients. In: Journal of Gastroenterology & Hepatology: Abstracts for Australian Gastroenterology Week 1999. Australian Gastroenterology Week 1999, Brisbane, (A201-A201). 4-8 Oct, 1999.

  • Herath, N. I., Kew, M. C., Whitehall, V. L., Young, J. P., Powell, L. W., Leggett, B. A. and Macdonald, G. A. (1999). Up-regulation of P73 in hepatocellular carcinoma. In: Hepatology : Abstracts of the AASLD 50th Annual Meeting & Postgraduate Courses. Entering a New Era, Wyndham Anatole Hotel, Dallas, Texas, (499A-499A). 5-9 November, 1999.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

Completed Supervision