Dr Ken Loh

Research Officer

Institute for Molecular Bioscience
z.loh1@imb.uq.edu.au
+61 7 334 62385

Overview

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Biomedical Science (Hons), The University of Queensland

Publications

  • Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018) Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 14: . doi:10.1172/jci.insight.120274

  • Lynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017) Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 2: 537-557. doi:10.1084/jem.20170298

  • Lohman, Rink-Jan, Hamidon, Johan K., Reid, Robert C., Rowley, Jessica A., Yau, Mei-Kwan, Halili, Maria A., Nielsen, Daniel S., Lim, Junxian, Wu, Kai-Chen, Loh, Zhixuan, Do, Anh, Suen, Jacky Y., Iyer, Abishek and Fairlie, David P. (2017) Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a. Nature Communications, 8 1: . doi:10.1038/s41467-017-00414-w

View all Publications

Publications

Journal Article

Conference Publication

  • Simpson, J., Loh, Z., Zhang, V, Spann, K., Upham, J. and Phipps, S. (2016). ABSENCE OF INTERFERON-beta PROMOTOR STIMULATOR-1 (IPS1) INDUCES BRONCHIOLITIS AND AN ASTHMA-LIKE PATHOLOGY IN RESPONSE TO PNEUMOVIRAL INFECTION. In: Respirology. International Congress of Immunology (ICI), Melbourne Australia, (118-118). Aug 21-26, 2016.

  • Werder, R., Lynch, J., Simpson, J., Loh, Z., Zhang, V, Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening type I and III interferon production. In: International Congress of Immunology (ICI), Melbourne, Australia, (555-555). 21-26 August 2016. doi:10.1002/eji.201670200

  • Lynch, J. P., Werder, R., Rogers, M., Lane, K., Loh, Z., Diener, K., Colonna, M., Forstner, C., Dennis, P., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Uphaem, J. and Phipps, S. (2016). Semaphorin 4A-Dependent Treg Cell Expansion by Plasmacytoid Dc Confers Protection Against Severe Viral Bronchiolitis and Subsequent Asthma. In: 4th Annual Meeting of The International Cytokine and Interferon Society (ICIS), San Francisco, United States, (108-108). Oct 16-19, 2016. doi:10.1016/j.cyto.2016.07.021

  • Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Upham, J. and Phipps, S. (2016). Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development. In: Respirology. International Congress of Immunology (ICI), Melbourne Australia, (121-121). Aug 21-26, 2016. doi:10.1111/resp.12755_3

  • Ullah, M. A., Revez, J., Loh, Z., Simpson, J., Zhang, , Bain, L., Varelias, A., Rose-John, S., Blumenthal, A., Smyth, M., Hill, G., Sukkar, M., Ferreira, M. A. and Phipps, S. (2015). IL-6R blockade attenuates experimental allergic asthma associated with activation of the IL-6 trans-signalling pathway. In: Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Barcelona Spain, (43-44). Jun 06-10, 2015.

  • Ullah, Ashik M., Pharm, M., Revez, J., Loh, Z., Simpson, J., Zhang, V, Bain, L., Varelias, A., Rose-John, S., Blumenthal, A., Smyth, M., Hill, G., Sukkar, M., Ferreira, M. and Phipps, S. (2015). Il-6R Blockade Attenuates Experimental Allergic Asthma Associated with Activation of the Il-6 Trans-Signalling Pathway. In: Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting 2015. Annual Scientific Meeting 2015 of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Gold Coast, QLD Australia, (32-32). 27 March - 1 April 2015. doi:10.1111/resp.12494_9

  • Loh, Z., Ullah, A., Zhang, V., Lynch, J., Werder, R., Simpson, J., Upham, J., Mazzone, S., Spann, K. and Phipps, S. (2015). Interferon Regulatory Factor 7 Protects Against Pneumovirus-Induced Airway Smooth Muscle Growth in Early Life. In: Abstracts of the Thoracic Society of Australia and New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting 2015. TSANZ 2015 Annual Scientific Meeting, Gold Coast, QLD Australia, (25-25). 28 March - 1 April 2015. doi:10.1111/resp.12494_7

  • Lynch, J. P., Werder, R. B., Rogers, M. J., Lane, K., Loh, Z., Simpson, J., Diener, K., Hayball, J., Zhang, P., Swiecki, M., Colonna, M., Haque, A., Spann, K., Mazzone, S. B., Hill, G. R., Upham, J. W. and Phipps, S. (2014). pDC expansion of nTreg limits severe Pneumovirus-induced bronchiolitis and attenuates the onset of virus-provoked asthma. In: Immunology. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, (124-124). Mar 27-Apr 01, 2015.

  • Lynch, J., Werder, R. B., Simpson, J., Loh, Z., Zhang, V., Sly, P. D., Mazzone, S., Upham, J. W. and Phipps, S. (2014). Anti-IL-33 ameliorates asthma onset and progression in response to virus and allergen co-exposure. In: Abstracts of the British Society for Immunology Annual Congress. Abstracts of the British Society for Immunology Annual Congress, Brighton, United Kingdom, (41-41). 1–4 December 2014.

  • Ullah, M. A., Loh, Z., Gan, W. J., Zhang, V., Lynch, J., Eacharath, J., Hughes, J. M., Armour, C. L., Phipps, S. and Sukkar, M. B. (2013). Hmgb1-Rage Axis Mediates House Dust Mite Induced Allergic Sensitization and Airway Inflammation. In: Special Issue: Abstracts of the Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, (25-25). 22 - 27 March 2013. doi:10.1111/resp.12045

  • Ullah, MD Ashik, Gan, Wan J., Loh, Zhixuan, Zhang, Vivian, Hughes, J. Margaret, Armour, Carol L., Phipps, Simon and Sukkar, Maria B. (2012). The activation of the receptor for advanced glycation end products (RAGE) contributes to the induction of Hdm-specific T(h)2 responses. In: Special Issue: Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, (13-13). 30 March - 4 April 2012. doi:10.1111/j.1440-1843.2012.02142.x

Other Outputs