Peter Csurhes is an immunologist with a strong research track record in multiple sclerosis (MS) research within UQ that has spanned 30 years.
Together with Emeritus Professor Michael Pender, Peter’s work in a number of preclinical research studies into the role that immunity to Epstein-Barr virus (EBV) plays in MS disease pathogenesis has translated to clinical trials testing of potentially ground-breaking new T cell immunotherapeutic treatments for progressive MS. Collaborative links between QIMR Berghofer, Royal Brisbane and Women’s Hospital and commercial partners have been established and clinical trials are ongoing.
After the retirement of Professor Pender, Peter has taken on a chief investigator role, and in 2023 gained successful NHMRC MRFF funding to continue research into the biology of the Epstein-Barr virus and the role it plays in the multiple sclerosis disease process.
Peter has also been involved in studying the role of reactivity to autoantigens in MS and in diseases of the peripheral nervous system including Guillain-Barre syndrome and CIDP.
For several years he worked on the immunology of potential malaria vaccine candidates and also worked part-time for 18 months on research into EBV-related cancers within the QIMR-Berghofer Medical Research Institute.
Journal Article: Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy
Ioannides, Zara A., Csurhes, Peter A., Douglas, Nanette L., Mackenroth, Gem, Swayne, Andrew, Thompson, Kate M., Hopkins, Tracey J., Green, Kerryn A., Blum, Stefan, Hooper, Kaye D., Wyssusek, Kerstin H., Coulthard, Alan and Pender, Michael P. (2021). Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy. Frontiers in Neurology, 12 652811, 652811. doi: 10.3389/fneur.2021.652811
Ioannides, Zara A., Csurhes, Peter A., Swayne, Andrew, Foubert, Philippe, Aftab, Blake T. and Pender, Michael P. (2021). Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis. Multiple Sclerosis Journal Experimental, Translational and Clinical, 7 (2), 1-12. doi: 10.1177/20552173211019772
Journal Article: Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan and Khanna, Rajiv (2020). Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis. JCI insight, 5 (20) e144624. doi: 10.1172/jci.insight.144624
How does Epstein-Barr virus infection lead to multiple sclerosis?
(2023–2027) NHMRC MRFF CTAI and EPCDRI Multiple Sclerosis
Ioannides, Zara A., Csurhes, Peter A., Douglas, Nanette L., Mackenroth, Gem, Swayne, Andrew, Thompson, Kate M., Hopkins, Tracey J., Green, Kerryn A., Blum, Stefan, Hooper, Kaye D., Wyssusek, Kerstin H., Coulthard, Alan and Pender, Michael P. (2021). Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy. Frontiers in Neurology, 12 652811, 652811. doi: 10.3389/fneur.2021.652811
Ioannides, Zara A., Csurhes, Peter A., Swayne, Andrew, Foubert, Philippe, Aftab, Blake T. and Pender, Michael P. (2021). Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis. Multiple Sclerosis Journal Experimental, Translational and Clinical, 7 (2), 1-12. doi: 10.1177/20552173211019772
Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan and Khanna, Rajiv (2020). Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis. JCI insight, 5 (20) e144624. doi: 10.1172/jci.insight.144624
Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan and Khanna, Rajiv (2018). Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis. JCI Insight, 3 (22) e124714. doi: 10.1172/jci.insight.124714
Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Burrows, Jacqueline M. and Burrows, Scott R. (2017). Defective T-cell control of Epstein-Barr virus infection in multiple sclerosis. Clinical and Translational Immunology, 6 (1) e126, 1-17. doi: 10.1038/cti.2016.87
Chan, Adeline, Yan, Jun, Csurhes, Peter, Greer, Judith and McCombe, Pamela (2015). Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: effect on outcome. Journal of Neuroimmunology, 286, 42-47. doi: 10.1016/j.jneuroim.2015.06.013
Blum, Stefan, Csurhes, Peter and McCombe, Pamela (2015). The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in. Journal of Neuroimmunology, 285, 53-56. doi: 10.1016/j.jneuroim.2015.05.017
Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Smith, Corey, Beagley, Leone, Hooper, Kaye D., Raj, Meenakshi, Coulthard, Alan, Burrows, Scott R. and Khanna, Rajiv (2014). Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis. Multiple Sclerosis Journal, 20 (11), 1541-1544. doi: 10.1177/1352458514521888
Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis
Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M. M. and Burrows, Scott R. (2014). Deficiency of CD8+ effector memory T cells is an early and persistent feature of multiple sclerosis. Multiple Sclerosis Journal, 20 (14), 1825-1832. doi: 10.1177/1352458514536252
Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome
Blum, Stefan, Csurhes, Peter, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2014). Killer immunoglobulin-like receptor and their HLA ligands in Guillain-Barré Syndrome. Journal of Neuroimmunology, 267 (1-2), 92-96. doi: 10.1016/j.jneuroim.2013.12.007
Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M. M. and Burrows, Scott R. (2012). CD8(+) T cells far predominate over CD4(+) T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines. Blood, 120 (25), 5085-5087. doi: 10.1182/blood-2012-06-437285
Pender, Michael P., Csurhes, Peter A., Pfluger, Casey M.M. and Burrows, Scott R. (2012). CD8 T cell deficiency impairs control of Epstein–Barr virus and worsens with age in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 83 (3), 353-354. doi: 10.1136/jnnp-2011-300213
Yan, Jun, Liu, Jia, Lin, Clement Yihao, Australia and New Zealand Multiple Sclerorsis Genetics Consortium, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2012). Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis. International Journal of Molecular Sciences, 13 (10), 13667-13679. doi: 10.3390/ijms131013667
Pender, Michael P., Csurhes, Peter A ., Pfluger, Casey M. M. and Burrows, Scott R. (2011). Decreased CD8(+) T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes. BMC Neurology, 11 (1) 95, 95-1-95-6. doi: 10.1186/1471-2377-11-95
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Ritchie, Matthew E., Liu, Ruijie, Carvalho, Benilton S., The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Irizarry, Rafael A., Brown, Matthew A., Csurhes, Peter A., Danoy, Patrick, Greer, Judith M., Hadler, Johanna, Pryce, Karena and Pender, Michael P. (2011). Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips. BMC Bioinformatics, 12 (4) 68, 68.1-68.12. doi: 10.1186/1471-2105-12-68
Strains of Epstein-Barr virus infecting multiple sclerosis patients
Brennan, R. M., Burrows, J. M., Bell, M. J., Bromham, L., Csurhes, P. A., Lenarczyk, A., Sverndal, J., Klintenstedt, J., Pender, M. P. and Burrows, S. R. (2010). Strains of Epstein-Barr virus infecting multiple sclerosis patients. Multiple Sclerosis, 16 (6), 643-651. doi: 10.1177/1352458510364537
Szvetko, Attila, Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter, Greer, Judith, Pender, Michael and Griffiths, Lyn (2010). Investigation of the [-/A](8) and C1236T genetic variations within the human toll-like receptor 3 gene for association with multiple sclerosis. Neurological Research [electronic resource], 32 (4), 438-441. doi: 10.1179/174313209X405155
McCombe, P. A. and Csurhes, P. A. (2010). T cells from patients with Guillain-Barre syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1. Journal of Clinical Neuroscience, 17 (4), 537-538. doi: 10.1016/j.jocn.2009.07.096
Bahlo, Melanie, Stankovich, Jim, Danoy, Patrick, Hickey, Peter F., Taylor, Bruce V., Browning, Sharon R., The Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Brown, Matthew A., Rubio, Justin P., Csurhes, Peter A., Greer, Judith, Pender, Michael P. and Pryce, Karena (2010). Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiology, Biomarkers and Prevention, 19 (3), 794-798. doi: 10.1158/1055-9965.EPI-09-0812
Bahlo, Melanie, Booth, David R., Broadley, Simon A., Brown, Matthew A., Foote, Simon J., Griffiths, Lyn R., Kilpatrick, Trevour J., Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M., Rubio, Justin P., Scott, Rodney J., Stankovich, Jim, Stewart, Graeme J., Taylor, Bruce V., Wiley, James, Clarke, Glynnis, Cox, Mathew B., Csurhes, Peter A., Danoy, Patrick, Drysdale, Karen, Field, Judith, Foote, Simon J., Greer, Judith M., Griffiths, Lyn R, Hadler, Johanna, McMorran, Brendan J., Jensen, Cathy J., Johnson, Laura J. ... Willoughby, Ernest (2009). Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics, 41 (7), 824-828. doi: 10.1038/ng.396
Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population
Mackenzie, Jason, Tajouri, Lotti, Szvetko, Attila, Weth, Verena, Moreau, Julie, Greer, Judith M., Csurhes, Peter A., Pender, Michael P. and Griffiths, Lyn R. (2009). Study of leukemia inhibitory factor polymorphism within an Australian multiple sclerosis population. Journal of the Neurological Sciences, 280 (1-2), 62-64. doi: 10.1016/j.jns.2009.01.026
Szvetko, Attila L., Jones, Ashleigh, Mackenzie, Jason, Tajouri, Lotti, Csurhes, Peter A., Greer, Judith M., Pender, Michael P. and Griffiths, Lyn R. (2009). An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population. Brain Research, 1255, 148-152. doi: 10.1016/j.brainres.2008.12.017
Pender, Michael P., Csurhes, Peter A., Lenarczyk, Aleksandra, Pfluger, Casey M. M. and Burrows, S. R. (2009). Decreased T cell reactivity to Epstein–Barr virus infected lymphoblastoid cell lines in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 80 (5), 498-505. doi: 10.1136/jnnp.2008.161018
Greer, Judith M., Csurhes, Peter A., Muller, Diane M. and Pender, Michael P. (2008). Correlation of blood T cell and antibody reactivity to myelin proteins with HLA type and lesion localization in multiple sclerosis. Journal of Immunology, 180 (9), 6402-6410. doi: 10.4049/jimmunol.180.9.6402
Inglis, H. R., Csurhes, P. A. and McCombe, P. A. (2007). Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflammatory demyelinating neuropathy. Journal of Neurology, Neurosurgery & Psychiatry, 78 (4), 419-422. doi: 10.1136/jnnp.2006.106617
Tajouri, Lotti, Fernandez, Francesca, Tajouri, Sophie, Detriche, Geraldine, Szvetko, Attila, Colson, Natalie, Csurhes, Peter, Pender, M. P. and Griffiths, Lyn R. (2007). Allelic Variation Investigation of the Estrogen Receptor Within an Australian Multiple Sclerosis Population. Journal of the Neurological Sciences, 252 (1), 9-12. doi: 10.1016/j.jns.2006.09.018
No Association Between MTHFR A1298C and MTRR A66G Polymorphisms, and MS in an Australian Cohort
Szvetko, A. L., Fowdar, J., Nelson, J., Colson, N., Tajouri, L., Csurhes, P. A., Pender, M. P. and Griffiths, L. R. (2007). No Association Between MTHFR A1298C and MTRR A66G Polymorphisms, and MS in an Australian Cohort. Journal of the Neurological Sciences, 252 (1), 49-52. doi: 10.1016/j.jns.2006.10.006
McCombe, Pamela A., Csurhes, Peter A. and Greer, Judith M. (2006). Studies of HLA associations in male and female patients with Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Journal of Neuroimmunology, 180 (1-2), 172-177. doi: 10.1016/j.jneuroim.2006.07.017
Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., Haupt, Larisa M., Csurhes, Peter, Pender, Michael P. and Griffiths, Lyn R. (2006). Genetic Investigation of Methylenetetrahydrofolate Reductase (MTHFR) and Catechol-O-Methyl Transferase (COMT) in Multiple Sclerosis. Brain Research Bulletin, 69 (3), 327-331. doi: 10.1016/j.brainresbull.2006.01.005
Csurhes, P. A., Sullivan, A-A., Green, K., Pender, M. P. and McCombe, P. A. (2005). T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. Journal of Neurology, Neurosurgery, and Psychiatry, 76 (10), 1431-1439. doi: 10.1136/jnnp.2004.052282
Increased Circulating T Cell Reactivity to GM1 Ganglioside in Patients with Guillain-Barre Syndrome
Csurhes, Peter A., Sullivan, Alice-Ann, Green, Kerryn, Greer, Judith M., Pender, Michael P. and McCombe, Pamela A. (2005). Increased Circulating T Cell Reactivity to GM1 Ganglioside in Patients with Guillain-Barre Syndrome. Journal of Clinical Neuroscience, 12 (4), 409-415. doi: 10.1016/j.jocn.2004.04.006
Tajouri, Lotti, Ovcaric, Micky, Curtain, Rob, Johnson, Matthew P., Griffiths, Lyn R., Csurhes, Peter, Pender, Michael P. and Lea, Rod A. (2005). Variation in The Vitamin D Receptor Gene is Associated With Multiple Sclerosis in an Australian Population. Journal of Neurogenetics, 19 (1), 25-38. doi: 10.1080/01677060590949692
Tajouri, Lotti, Martin, Virginie, Ovcaric, Micky, Curtain, Rob P., Lea, Rod A., Csurhes, Peter, Pender, Michael P. and Griffiths, Lyn R. (2004). Investigation Of An Inducible Nitric Oxide Synthase Gene (NOS2A) Polymorphism In A Multiple Sclerosis Population. Brain Research Bulletin, 64 (1), 9-13. doi: 10.1016/j.brainresbull.2004.04.019
Greer, Judith M., Csurhes, Peter A., Pender, Michael P. and McCombe, Pamela A. (2004). Effect Of Gender On T-Cell Proliferative Responses To Myelin Proteolipid Protein Antigens In Patients With Multiple Sclerosis And Controls. Journal of Autoimmunity, 22 (4), 345-352. doi: 10.1016/j.jaut.2004.03.004
Tajouri, Lotti, Ferreira, Linda, Ovcaric, Micky, Curtain, Rob, Lea, Rod, Csurhes, Peter A., Pender, Michael P. and Griffiths, Lyn R. (2004). Investigation of a Neuronal Nitric Oxide Synthase Gene (NOS1) Polymorphism in a Multiple Sclerosis Population. Journal of the Neurological Sciences, 218 (1-2), 25-28. doi: 10.1016/j.jns.2003.10.006
Athanasas-Platsis, S., Zhang, B., Hillyard, N. C., Cavanagh, A. C., Csurhes, P. A., Morton, H. and McCombe, P. A. (2003). Early pregnancy factor suppresses the infiltration of lymphocytes and macrophages in the spinal cord of rats during experimental autoimmune encephalomyelitis but has no effect on apoptosis. Journal of the Neurological Sciences, 214 (1-2), 27-36. doi: 10.1016/S0022-510X(03)00170-9
Pender, Michael P., Csurhes, Peter A., Wolfe, Nigel P., Hooper, Kaye D., Good, Michael F., McCombe, Pamela A. and Greer, Judith M. (2003). Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis. Journal of Clinical Neuroscience, 10 (1), 63-66. doi: 10.1016/S0967-5868(02)00270-9
Pender, Michael P., Csurhes, Peter A., Greer, Judith M., Mowat, Paul D., Henderson, Robert D., Cameron, Kaye D., Purdie, David M., McCombe, Pamela A. and Good, Michael F. (2000). Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis than in Healthy Subjects. Journal of Immunology, 165 (9), 5322-5331. doi: 10.4049/jimmunol.165.9.5322
Greer, J. M., Csurhes, P. A., Cameron, K. D., McCombe, P. A., Good, M. F. and Pender, M. P. (1997). Increased Immunoreactivity to Two Overlapping Peptides of Myelin Proteolipid Protein in Multiple Sclerosis. Brain, 120 (8), 1447-1460. doi: 10.1093/brain/120.8.1447
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1997). Corrigendum to "A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein" (J. Neuroimmunol. 70, 65-74). Journal of Neuroimmunology, 73 (1-2), 213-213.
Rzepczyk, Christine M., Hale, Kate, Woodroffe, Nick, Bobogare, Albino, Csurhes, Peter, Ishii, Akira and Ferrante, Antonio (1997). Humoral immune responses of Solomon Islanders to the merozoite surface antigen 2 of Plasmodium falciparum show pronounced skewing towards antibodies of the immunoglobulin G3 subclass. Infection and Immunity, 65 (3), 1098-1100.
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1997). Erratum: A study of human T-cell lines generated from multiple sclerosis patients and controls by stimulation with peptides of myelin basic protein (J. Neuroimmunol. 70, 65-74 (1996)). Journal of Neuroimmunology, 73 (1-2), 213-213. doi: 10.1016/S0165-5728(96)00222-6
Pender, M. P., Csurhes, P. A., Houghten, R. A., McCombe, P. A. and Good, M. F. (1996). A Study Of Human T-Cell Lines Generated From Multiple Sclerosis Patients And Controls By Stimulation With Peptides Of Myelin Basic Protein. Journal of Neuroimmunology, 70 (1), 65-74. doi: 10.1016/S0165-5728(96)00105-1
Rzepczyk, CM, Anderson, KL, Crurshes, PA, Baxter, EP, Kere, N, Irving, D, Dyer, S and Jones, GL (1992). Epitopic Specificity of the Human Immune-Response to the Invariant Region of a Polymorphic Plasmodium-Faciparum Merozoite Surface-Antigen. Journal of Protozoology Research, 2 (3), 102-111.
Comparative study of the T cell response to two allelic forms of a malaria vaccine candidate protein
Rzepczyk, C. M., Csurhes, P. A., Saul, A. J., Jones, G. L., Dyer, S., Chee, D., Goss, N. and Irving, D. O. (1992). Comparative study of the T cell response to two allelic forms of a malaria vaccine candidate protein. Journal of Immunology, 148 (4), 1197-1204.
Rzepczyk, C. M., Anderson, K. L., Csurhes, P. A., Baxter, E. P., Kere, N., Irving, D., Dyer, S. and Jones, G. L. (1992). Epitopic specificity in the human immune response to the invariant region of a polymorphic Plasmodium falciparum merozoite surface antigen. Journal of Protozoology Research, 2, 102-111.
The role of single amino acids in the recognition of a T cell epitope
Suhrbier, A., Rodda, S. J., Ho, P. C., Csurhes, P., Dunckley, H., Saul, A., Geysen, H. M. and Rzepczyk, C. M. (1991). The role of single amino acids in the recognition of a T cell epitope. Journal of Immunology, 147 (8), 2507-2513.
Rzepczyk, C. M., Csurhes, P. A., Lord, R. and Matile, H. (1990). Synthetic peptide immunogens eliciting antibodies to Plasmodium falciparum sporozoite and merozoite surface antigens in H-2b and H-2k mice. Journal of Immunology, 145 (8), 2691-2696.
Pender, M. P., Csurhes, P. A., Smith, C., Douglas, N. L., Neller, M. A., Beagley, L., Rehan, S., Hopkins, T. J., Thompson, K. M., Blum, S., Green, K. A., Ioannides, Z. A., Coulthard, A., Hooper, K. D., Burrows, S. R. and Khanna, R. (2017). Safety and clinical improvement in a phase I trial of autologous Epstein-Barr virus-specific T-cell therapy in patients with progressive multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications.
Pender, Michael, Csurhes, Peter, Smith, Corey, Douglas, Nanette, Neller, Michelle, Beagley, Leone, Rehan, Sweera, Hopkins, Tracey, Thompson, Kate, Blum, Stefan, Green, Kerryn, Ioannides, Zara, Coulthard, Alan, Hooper, Kaye, Burrows, Scott and Khanna, Rajiv (2017). Symptomatic and objective clinical improvement in progressive multiple sclerosis patients treated with autologous Epstein-Barr virus-specific T cell therapy: interim results of a phase I trial. 69th Annual Meeting of the American Academy of Neurology (AAN), Boston, Massachusetts, 22-28 April 2017. Philadelphia, PA, United States: Lippincott Williams & Wilkins.
Impaired T cell control of Epstein-Barr virus infection in multiple sclerosis
Pender, Michael, Csurhes, Peter and Burrows, Scott (2015). Impaired T cell control of Epstein-Barr virus infection in multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne, Australia, Oct 29-30, 2015. London, EC1Y 1SP United Kingdom: SAGE PUBLICATIONS LTD. doi: 10.1177/1352458515616527
Killer immunoglobulin-like receptors and their HLA ligands in Guillain-Barré syndrome
Blum, Stefan, Csurhes, Peter, Reddel, Stephen, Spies, Judy and McCombe, Pamela (2014). Killer immunoglobulin-like receptors and their HLA ligands in Guillain-Barré syndrome. ANZAN Annual Scientific Meeting 2014, Adelaide, South Australia, Australia, May 2014. Elsevier. doi: 10.1016/j.jocn.2014.06.032
Pender, M. P., Csurhes, P. A., Smith, C., Beagley, L., Hooper, K. D., Raj, M., Coulthard, A., Burrows, S. R. and Khanna, R. (2013). Treatment of secondary progressive multiple sclerosis by boosting CD8 T cell immunity to Epstein-Barr virus using a novel adoptive immunotherapy. 29th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis / 18th Annual Conference of Rehabilitation in MS, Copenhagen Denmark, 2 - 5 October 2013. London, United Kingdom: Sage Publications Ltd.. doi: 10.1177/1352458513502429
Pender, M. P., Csurhes, P. A., Pfluger, C. M. M. and Burrows, S. R. (2011). CD8+T cell deficiency impairs control of Epstein-Barr virus and worsens with age in multiple sclerosis. LONDON: SAGE PUBLICATIONS LTD.
Infection with specific strains of Epstein-Barr virus are a risk factor for multiple sclerosis
Brennan, Rebekah M., Burrows, Jacqueline M., Bell, Melissa J., Lenarczyk, Aleksandra, Csurhes, Peter A., Pender, Michael. and Burrows, Scott R. (2008). Infection with specific strains of Epstein-Barr virus are a risk factor for multiple sclerosis. Joint World Congress on Treatment and Research in Multiple Sclerosis: 13th Annnual Meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis / 24th Congress of the European Committee for Treatment and Research in Multiple Sclerosis / 5th Congress of the Latin American Committee for Treatment and Research in Multiple Sclerosis, Montréal, QC, Canada, 17-20 September 2008. London, U.K.: Sage Publications. doi: 10.1177/1352458508096399
Role of autoreactivity against myelin proteolipid protein in multiple sclerosis
Greer, Judith, Csurhes, Peter, Muller, Diane and Pender, Michael (2008). Role of autoreactivity against myelin proteolipid protein in multiple sclerosis. ISNI 2008: 9th International Congress of Neuroimmunology, Fort Worth, TX, U.S.A., October 26-30, 2008. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jneuroim.2008.08.001
Pender, M. P., Csurhes, P. A. and Greer, J. M. (2006). T-cell reactivity to myelin proteolipid protein drives the development of brainstem and cerebellar lesions in multiple sclerosis. 8th International Conference on Neuroimmunology, Nagoya, Japan, 15-19 October 2006. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.jneuroim.2006.07.002
McCombe, P. A., Csurhes, P. A., Alizart, M. A. and Greer, J. M. (2005). HLA-DR2 is associated with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in females, but not males. 5th Annual Meeting of the Federation-of-Clinical-Immunology-Society, Boston, MA, U.S.A., 12-16 May 2005. Orlando, Florida: Academic Press.
Clinical and immunological findings in patients with concurrent MS and autoimmune thyroid disease
Greer, J. M., Tan, K. M., Wolfe, N. P., Csurhes, P. A. and Pender, M. P. (2004). Clinical and immunological findings in patients with concurrent MS and autoimmune thyroid disease. ACTRIMS 03, San Francisco, 19 October, 2003. United Kingdom: Arnold.
Pender, M. P., Csurhes, P. A., Wolfe, N. P., Cameron, K. D., McCombe, P. A., Greer, J. M. and Good, M. F. (2002). Blood T-cell reactivity to gangliosides GM3 and GQ1b is increased in patients with primary progressive multiple sclerosis. 127th Annual Meeting of the American Neurological Association, New York City, NY, USA, October 12-16 2002. NEW YORK: WILEY-LISS.
T cell responses to gangliosides in patients with inflammatory neuropathy
McCombe, P. A., Sullivan, A. A., Alizart, M. A., Csurhes, P. A., Greer, J. M. and Pender, M. P. (2002). T cell responses to gangliosides in patients with inflammatory neuropathy. Xth International Congress on Neuromuscular Diseases, Vancouver, Canada, 07-12 Jul 2002. Amsterda, The Netherlands: Elseiver. doi: 10.1016/S0022-510X(02)80069-7
Pender, M. P., Csurhes, P. A., Greer, J. M., Mowat, P. D., Henderson, R. D., Cameron, K. D., McCombe, P. A. and Good, M. F. (1999). Fluctuations in the frequencies of circulating myelin-reactive T cells in healthy subjects and patients with multiple sclerosis. ECTRIMS/ACTRIMS'99, Basel, Switzerland, 15 - 18 Sept, 1999. Basingstoke, England: Stockton Press.
The role of PMP-22 as an autoantigen in GBS and CIDP
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T-cell reactivity to peptides of proteolipid protein and myelin basic protein in multiple sclerosis
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How does Epstein-Barr virus infection lead to multiple sclerosis?
(2023–2027) NHMRC MRFF CTAI and EPCDRI Multiple Sclerosis