Dr Trung Ngo

Librarian

Learning and Research Services (University of Queensland Library)

Honorary Fellow

Mater Research Institute-UQ
Faculty of Medicine

Overview

I completed a PhD in Neuroscience (2009) with eminent Australian neurobiologist Jack Pettigrew (FRS). My research employed caloric vestibular stimulation (CVS) — a simple, non-invasive (unihemispheric) brain stimulation technique — to demonstrate evidence for a novel neural mechanism of visual rivalry: the interhemispheric switch (IHS) model.

I was awarded an NHMRC postdoctoral clinical research fellowship to continue investigating rivalry mechanisms and abnormalities in psychiatric groups. From 2010 I was project coordinator and technology lead for this work at Monash Alfred Psychiatry Research Centre. My fellowship studies also examined CVS as a potential therapeutic intervention in persistent (chronic) pain disorders.

I am continuing this body of work with the following research projects:

[A] Testing and validating novel visual task measures for identifying individuals at increased risk of developing mental illness (e.g., young people, at-risk/early psychosis cohorts).

[B] Effectiveness of non-invasive vestibular neuromodulation protocols as a treatment for psychiatric and neurological illnesses (e.g., depression, bipolar disorder, post-traumatic stress disorder, dementia, epilepsy, persistent pain).

[C] Development of autonomic activity recording devices with real-time analysis output of endogenous rhythms and their clinical (diagnostic) utility in psychiatry, neurology and sleep medicine.

[D] Phylogenetics and evolution of bistable switching — from bacterial chemotaxis and fruit fly optomotor responses to binary decision-making in mammals (e.g., approach/avoidance choice behaviour) and disordered mood/cognitive states in humans (e.g., mania/depression, denial/insight).

Research Interests

  • Minimal phenotyping: Perceptual and cognitive testing
    Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).
  • Vestibular brain stimulation: Applications and mechanisms
    Clinical applications of non-invasive vestibular neuromodulation, and the genetics and neuroimaging of its therapeutic response, with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').
  • Biomedical device & software development
    Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing IHS rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibular neuromodulation.
  • Phylogenetics & evolution of bistable switching and the vestibular system
    Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans).
  • Scientometrics and research outcome measures
    Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using AI, machine learning and big data analysis algorithms.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Science with Honours Class Honours, The University of Queensland
  • Bachelor of Arts, The University of Queensland

Publications

View all Publications

Available Projects

  • The following research projects are open to interested (and motivated) individuals from a wide range of background disciplines/professional experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics and statistics, biological/life sciences, medicine and allied health, information technology, psychology:

    Minimal phenotyping: Perceptual and cognitive testing

    • Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    Vestibular brain stimulation: Applications and mechanisms

    • Clinical applications of non-invasive vestibular neuromodulation, and the genetics and neuroimaging of its therapeutic response, with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').

    Biomedical device & software development

    • Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing IHS rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibular neuromodulation.

    Phylogenetics & evolution of bistable switching and the vestibular system

    • Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans).

    Scientometrics and research outcome measures

    • Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using AI, machine learning and big data analysis algorithms.

View all Available Projects

Publications

Featured Publications

Book Chapter

  • Ngo, Trung T., Barsdell, Wendy N., Law, Phillip C. F. and Miller, Steven M. (2013). Binocular rivalry, brain stimulation and bipolar disorder. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 211-252) Amsterdam, The Netherlands: John Benjamins Publishing Company. doi:10.1075/aicr.90.09ngo

  • Wade, Nicholas J. and Ngo, Trung T. (2013). Early views on binocular rivalry. In S. M. Miller (Ed.), The constitution of visual consciousness: Lessons from binocular rivalry (pp. 77-108) Amsterdam, The Netherlands: John Benjamins Publishing Company. doi:10.1075/aicr.90.04wad

Journal Article

Conference Publication

  • Ngo, T. T., Couvy-Duchesne, B., Cuéllar-Partida, G., Rentería, M. E., Colodro Conde, L., Gordon, S. D., Hansell, N. K., Law, P. C. F., Miller, S. M., Medland, S. E., Wright, M. J. and Martin, N. G. (2016). Association of psychiatric profile measures with binocular rivalry rate (BRR): Implications for slow BRR as an endophenotype for bipolar disorder. In: Abstracts from the ISTS Satellite Meeting June 20, 2016, Brisbane. International Society for Twin Studies Satellite Meeting, QIMR Berghofer Medical Research Institute, Brisbane, Australia, (518-518). 20 June 2016. doi:10.1017/thg.2016.66

  • Ngo, Trung T., Law, Phillip C. F., Foley, Sharon R. and Capra, Carina (2016). Examining a novel visual task for identifying individuals at increased risk of developing mental illness. In: BLiSS 2016 — Brisbane Life Science ECR Symposium, Brisbane, Australia, (). 2 December 2016.

  • Ngo, T. T., Barsdell, W. N., Arnold, C. A., Chou, M. J., New, P. W., Hill, S. T., Nunn, A. K., Brown, D. J., Gibson, S. J. and Miller, S. M. (2015). Bedside neuromodulation of persistent pain and allodynia using caloric vestibular stimulation: An effectiveness trial. In: Abstracts from the XXII World Congress of Neurology (WCN 2015). 22nd World Congress of Neurology, Santiago, Chile, (e91-e91). 31 October – 5 November 2015. doi:10.1016/j.jns.2015.08.304

  • Miller, S. M., Law, P. C. F. and Ngo, T. T. (2015). Effects of drift speed and stimulus size on binocular rivalry rate and mixed percept duration in healthy individuals: Implications for endophenotype studies in clinical psychiatric groups. In: Society for Neuroscience Abstracts: 45th Annual Meeting of the Society for Neuroscience. Society for Neuroscience 45th Annual Meeting, Chicago, USA, (). 17–21 October 2015.

  • Ngo, T. T., Law, P. C. F. and Miller, S. M. (2015). Investigating optimal stimuli for large-scale endophenotype studies of binocular rivalry rate in bipolar disorder. In: Society for Mental Health Research Conference 2015, Sofitel Hotel, Brisbane, Qld, (156-156). 2–4 December 2015.

  • Law, P. C. F., Riddiford, J. A., Gurvich, C. T., Ngo, T. T. and Miller, S. M. (2015). Investigating the effect of stimulus variables and eye movement profiles on binocular rivalry rate: Implications for large-scale endophenotype studies. In: ICON 2014: XII International Conference on Cognitive Neuroscience, Brisbane Convention and Exhibition Centre, Queensland, Australia, (). 27–31 July 2014. doi:10.3389/conf.fnhum.2015.217.00291

  • Anderson-Schmidt, H., Gebel, L., Callista, K., Nierste, B., Glöckner, A., Budde, M., Heilbronner, U., Martin, N. G., Ngo, T. T., Miller, S. M. and Schulze, T. G. (2013). A longitudinal investigation of binocular rivalry rate (BRR) in major psychotic disorders. In: 21st World Congress of Psychiatric Genetics, Boston, USA, (). 17–21 October 2013.

  • Law, P. C. F., Paton, B. K., Thomson, R. H., Liu, G. B., Miller, S. M. and Ngo, T. T. (2013). Development of a standardized system for perceptual rivalry research. In: 33rd Annual Meeting of the Australian Neuroscience Society, Melbourne Exhibition and Convention Centre, Victoria, Australia, (147-147). 3–6 February 2013.

  • Law, P. C. F., Riddiford, J. A., Gurvich, C. T., Ngo, T. T. and Miller, S. M. (2013). No relationship between binocular rivalry rate and eye movement variables. In: 4th Australasian Cognitive Neuroscience Conference, Monash University, Melbourne, Australia, (). 28 November – 1 December 2013. doi:10.3389/conf.fnhum.2013.212.00116

  • Barsdell, W. N., Law, P. C. F., Gibson, S. J., Miller, S. M. and Ngo, T. T. (2013). Persistent pain and perceptual rivalry interactions: An exploratory study. In: Abstracts of the Australian Pain Society's 33rd Annual Scientific Meeting. 33rd Annual Scientific Meeting of the Australian Pain Society, Canberra, Australia, (422-422). 17–20 March 2013.

  • Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Wright, M. J. and Martin, N. G. (2012). Genetic contribution to individual variation in binocular rivalry rate, an endophenotype for bipolar disorder. In: Abstracts of the 5th Biennial Conference of the International Society for Bipolar Disorders. 5th Biennial Conference of the International Society for Bipolar Disorders, Istanbul, Turkey, (103-103). 14–17 March 2012. doi:10.1111/j.1399-5618.2012.00981.x

  • Law, P. C. F., Paton, B., Liu, G. B., Ngo, T. T. and Miller, S. M. (2011). Development of a binocular rivalry testing system for large-scale psychiatric and genetic studies. In: Proceedings of the First Scientific Meeting of Biological Psychiatry Australia. 1st Scientific Meeting of Biological Psychiatry Australia, Melbourne Cricket Ground, Melbourne, Australia, (51-51). 7–8 November 2011.

  • Barsdell, W. N., Ngo, T. T., Chou, M. J., Arnold, C. A., Nunn, A., Hill, S. T., Brown, D. J., Gibson, S. J. and Miller, S. M. (2011). Effects of a non-invasive vestibular-cortical activation technique on subjective ratings of persistent pain and mood. In: Proceedings of the First Scientific Meeting of Biological Psychiatry Australia. 1st Scientific Meeting of Biological Psychiatry Australia, Melbourne Cricket Ground, Melbourne, Australia, (). 7–8 November 2011.

  • Ngo, T. T., Barsdell, W. N., Chou, M. J., Arnold, C., Nunn, A., Hill, S. T., Brown, D. J., Gibson, S. J. and Miller, S. M. (2011). Effects of a non-invasive vestibulocortical activation technique in persistent pain states. In: 8th IBRO World Congress of Neuroscience, Florence, Italy, (). 14–18 July, 2011.

  • Palmer, C. J., Paton, B., Ngo, T. T., Thomson, R. H., Hohwy, J. and Miller, S. M. (2010). An association between inequity-averse moral preference and risk aversion in decision-making. In: Proceedings of the Australian Neuroscience Society and Australian Physiological Society Joint Meeting. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, (175-175). 31 January – 3 February 2010.

  • Ngo, T. T., Chou, M. J., Nunn, A., Arnold, C., Brown, D. J., Gibson, S. J. and Miller, S. M. (2010). Caloric vestibular stimulation reduces allodynia in complex regional pain syndrome (CRPS) Type II. In: Proceedings of the Australian Neuroscience Society and Australian Physiological Society Joint Meeting. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, (83-83). 31 January – 3 February 2010.

  • Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). Genetic contribution to individual variation in binocular rivalry rate. In: Proceedings of the Australian Neuroscience Society and Australian Physiological Society Joint Meeting. ANS/AuPS 2010 — 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society, Sydney Convention & Exhibition Centre, Darling Harbour, Sydney, (173-173). 31 January – 3 February 2010.

  • Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). Genetic contribution to individual variation in binocular rivalry rate, an endophenotype for bipolar disorder. In: Proceedings of the 18th World Congress of Psychiatric Genetics. 18th World Congress of Psychiatric Genetics, Athens, Greece, (). 3–7 October 2010.

  • Miller, S. M., Hansell, N. K., Ngo, T. T., Liu, G. B., Pettigrew, J. D., Martin, N. G. and Wright, M. J. (2010). The genetics of binocular rivalry. In: Proceedings of the 7th FENS Forum of European Neuroscience. 7th FENS Forum of European Neuroscience, Amsterdam, The Netherlands, (139.14-139.14). 3–7 July, 2010.

  • Miller, S. M. and Ngo, T. T. (2007). Caloric vestibular stimulation: From diagnosis to therapy?. In: Proceedings of the World Psychiatric Association International Congress. World Psychiatric Association International Congress 2007, Melbourne Convention Centre, Melbourne, Australia, (A150-A150). 28 November – 2 December 2007. doi:10.1080/00048670701724597

  • Ngo, T. T. and Miller, S. M. (2007). Caloric vestibular stimulation: Perceptual rivalry and beyond. In: Proceedings of the 7th IBRO World Congress of Neuroscience. 7th IBRO World Congress of Neuroscience, Melbourne Convention Centre, Melbourne, Australia, (300-300). 12–17 July 2007.

  • Ngo, T. T., Miller, S. M., Liu, G. B., Tilley, A. J. and Pettigrew, J. D. (2002). Coherence (full-field) rivalry but not half-field rivalry is mediated by interhemispheric switching. In: Proceedings of the Australian Neuroscience Society. Australian Neuroscience Society Annual Meeting, Sydney, (214-214). 3 - 6 February 2002.

  • Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2002). Predominance of Rubin’s vase perceptual alternations changes with unilateral caloric vestibular stimulation. In: Society for Neuroscience Abstracts: 32nd Annual Meeting of the Society for Neuroscience. 32nd Annual Meeting of the Society for Neuroscience, Orlando, Florida, USA, (). 3–7 November 2002.

  • Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2001). Coherence rivalry and caloric stimulation: Further support for an interhemispheric switch mechanism. In: 21st Annual Meeting of the Australian Neuroscience Society, Brisbane Convention Centre, Australia, (207-207). 28 - 31 January 2001.

  • Miller, S. M., Geffen, L. B., Gynther, B. D., Heslop, K. R., Liu, G. B., Ngo, T. T., Mitchell, P. B. and Pettigrew, J. D. (2001). Temporal properties of binocular rivalry in bipolar disorder, schizophrenia and major depression. In: Proceedings of the Australian Neuroscience Society. 21st Annual Meeting of the Australian Neuroscience Society, Brisbane Convention Centre, Australia, (207-207). 28–31 January 2001.

  • Miller, S. M., Liu, G. B., Ngo, T. T., Geffen, L. B., Gynther, B. D., Mitchell, P. B. and Pettigrew, J. D. (2000). Binocular rivalry is slow in bipolar disorder but not in schizophrenia or major depression. In: Congress of the Association of European Psychiatrists, Prague, Czech Republic, (283s-283s). 28 October–1 November, 2000. doi:10.1016/S0924-9338(00)94234-2

  • Ngo, T. T., Miller, S. M., Liu, G. B. and Pettigrew, J. D. (2000). Coherence rivalry: The eyes don't have it!. In: Paul M. Pilowsky, Proceedings Of The Australian Neuroscience Society. 20th Annual Meeting Of The Australian Neuroscience Society, Melbourne Convention Centre, Melbourne, Victoria, Australia, (154-154). 30 Jan - 2 Feb, 2000.

  • Miller, S. M., Ngo, T. T., Liu, G. B. and Pettigrew, J. D. (2000). Unilateral caloric stimulation changes perceptual predominance during binocular rivalry with oblique gratings. In: Proceedings of the Australian Neuroscience Society. 20th Annual Meeting of the Australian Neuroscience Society, Melbourne Convention Centre, Melbourne, Victoria, Australia, (226-226). 30 January – 2 February 2000.

  • Ngo, T. T., Miller, S. M., Liu, G. B., Tilley, A. J., Broerse, P. J. and Pettigrew, J. D. (1999). A common neural mechanism for reversible figures and binocular rivalry?. In: Proceedings of the Australian Neuroscience Society. 19th Annual Meeting Of The Australian Neuroscience Society, Hobart, TAS Australia, (193-193). 31 January - 3 February 1999.

  • Miller, S. M., Liu, G. B., Ngo, T. T., Gynther, B. D., Geffen, L. B., Mitchell, P. B., Martin, N. G. and Pettigrew, J. D. (1999). Clinical studies of binocular rivalry. In: Proceedings of the 5th IBRO World Congress of Neuroscience. 5th IBRO World Congress of Neuroscience, Jerusalem, Israel, (111-111). 11–15 July 1999.

  • Miller, S. M., Liu, G. B., Ngo, T. T., Hooper, G., Riek, S., Carson, R. G. and Pettigrew, J. D. (1999). Neural mechanisms in binocular rivalry: Studies of image bias and alternation rate. In: Proceedings of the Australian Neuroscience Society. 19th Annual Meeting Of The Australian Neuroscience Society, Hobart, TAS, Australia, (23-23). 31 January – 3 February 1999.

  • Miller, S. M., Ngo, T. T., Liu, G. B., Gynther, B. D., Geffen, L. B., Mitchell, P. B., Martin, N. G. and Pettigrew, J. D. (1999). Slow binocular rivalry in bipolar disorder. In: 1999 Annual Scientific Meeting of the Australasian Society for Psychiatric Research. Annual Scientific Meeting of the Australasian Society for Psychiatric Research, University of New South Wales, Sydney, Australia, (). 2–3 December 1999.

Other Outputs

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.

  • The following research projects are open to interested (and motivated) individuals from a wide range of background disciplines/professional experience, e.g., biomedical/electrical engineering, physics, computer science, mathematics and statistics, biological/life sciences, medicine and allied health, information technology, psychology:

    Minimal phenotyping: Perceptual and cognitive testing

    • Multi-platform development of candidate diagnostic/endophenotype perceptual and cognitive task measures for large-scale user-friendly testing in genotyped and at-risk/youth cohorts (e.g., web, mobile, tablet, gaming, virtual reality).

    Vestibular brain stimulation: Applications and mechanisms

    • Clinical applications of non-invasive vestibular neuromodulation, and the genetics and neuroimaging of its therapeutic response, with the aim of elucidating novel electroceutical pathways, response biomarkers and personalised treatment protocols across a spectrum psychiatric and neurological disorders ('electroceutomics').

    Biomedical device & software development

    • Development of portable/wearable devices with integrated software applications for (i) perceptual rivalry viewing (e.g., stereoscopic 3D displays), data collection and analyses; (ii) probing IHS rhythms (e.g., autonomic respiratory/nasal cycle periodicity); and (iii) inducing, recording and real-time analysis output of vestibular neuromodulation.

    Phylogenetics & evolution of bistable switching and the vestibular system

    • Investigating the comparative genetics, neural network dynamics (e.g., vestibulocortical circuitry) and molecular mechanisms of bistable (anti-phase) interhemispheric oscillations — which have been observed across a range of phenotypes (e.g., biological rhythms, autonomic functions, oculomotor activity, perception/attention, cognitive/behaviour changes) and in different species (e.g., Drosophila, sandlance, birds, cetaceans, rodents, humans).

    Scientometrics and research outcome measures

    • Developing quantitative indicators of interdisciplinary conceptual and empirical synthesis, scientific impact and translational outcomes using AI, machine learning and big data analysis algorithms.