Dr Run Zhang

ARC Discovery Early Career Research

Australian Institute for Bioengineering and Nanotechnology
+61 7 334 63806


Dr Run Zhang is currently an Australian Research Council Discovery Early Career Researcher (ARC DECRA) in Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (UQ).

Dr Zhang received his PhD degree in Dalian University of Technology in 2012. He moved to the Physics and Astronomy Department of Macquarie University as a postdoctoral research fellow immediately after finishing his PhD. Then, he won a highly competitive Macquarie University Research Fellowship (MQRF), and took up this independent position in the Department of Chemistry and Biomolecular Science (CBMS) in 2013. In 2015, he was appointed as a visiting researcher in AIBN, UQ. In 2016, he re-located to AIBN, UQ to work within Professor Zhi Ping (Gordon) Xu's group.

Since 2011, Dr Zhang has attracted over 1.3 million competitive research funding nationally and internationally, such as two prestigious research fellowship (Macquarie University Research Fellowship, ARC DECRA Research Fellowship) on developing next generation bioprobes for highly sensitive and selective detection of biomarkers in live bodies, two Macquarie University Research Infrastructure Block Grants on engineering of cutting edge optical bioimaging technologies, one NHMRC project on visualisation and early prediction of ROS-mediated treatment response in liver cancer by a novel nanoplatform. Following his early success on the development of bioprobes for reactive oxygen/nitrogen species (ROS/RNS), this NHMRC project will design and prepare next generation nanoprobes for quantification and visualisation of ROS in cancer development and treatment.

Research Interests

  • Biosensors to probe highly reactive biomolecules
    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
  • Bionanoprobes for deep tissue imaging
    fabrication of responsive Ln-doped nanomaterials for imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
  • Chemosensors for the detection of environmental pollutants
    development of ultra-sensitive chemosensors for the detection of heavy metals, toxic anions and gases.
  • Time-gated luminescence bioassay
    development of novel luminescent probes with long emission lifetime to remove autofluorescence, allowing background-free sensing and bioimaging.
  • Functional nanomaterial for tumour early diagnosis and imaging guided tumour therapy
    including photodynamic therapy (PDT), and chemotherapy


  • Doctor of Engineering, Dalian University of Technology (PRC)


View all Publications


  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Available Projects

View all Available Projects


Journal Article

Conference Publication

  • Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. In: Hutchinson, MR and Goldys, EM, Spie Biophotonics Australasia. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, (). 17 - 19 October 2016. doi:10.1117/12.2242978

  • Zhao, Jiangbo, Zheng, Xianlin, Schartner, Erik P., Ionescu, Paul, Zhang, Run, Nguyen, Tich-Lam, Jin, Dayong and Ebendorff-Heidepriem, Heike (2016). Upconversion nanocrystals doped glass: a new paradigm for integrated optical glass. In: Photonics and Fiber Technology 2016 (ACOFT, BGPP, NP). Photonics and Fiber Technology , Sydney, Australia, (). 5–8 September 2016. doi:10.1364/acoft.2016.am5c.7

  • Zhang, Peng, Ruan, Shuai, Zhang, Run, Pullen, Benjamin, Zhang, Xiaozhou, Purdey, Malcolm Stuart, Ebendorff-Heidepriem, Heike, Abell, Andrew, Ding, Liyun, Tang, Ming and Ruan, Yinlan (2014). Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex. In: Asia-Pacific Optical Sensors Conference, APOS 2016. Asia-Pacific Optical Sensors Conference, APOS 2016, Shanghai China, (). 11-14 October 2016. doi:10.1364/APOS.2016.W3A.5

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.