Dr Run Zhang

ARC Discovery Early Career Research

Australian Institute for Bioengineering and Nanotechnology
r.zhang@uq.edu.au
+61 7 334 63806

Overview

  • 2017-now ARC DECRA Fellow, AIBN, The University of Queensland
  • 2016-2017 Research Associate, AIBN, The University of Queensland
  • 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
  • 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
  • July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China

Research Support: Since 2011, Dr Zhang has attracted 9 research grants (> 2 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for biomarkers detection within body), 1 NHMRC Project grant (New Investigator, Visualisation and Early Prediction of ROS-mediated Treatment Response in Liver Cancer by A Novel Nanoplatform, APP1125794, 2017-2019), 1 UQ ECR grant, 1 NSFC grant (China) and another 3 grants from DLUT and MQ.

Research Output: Dr Zhang’s research focuses on the development of biosensors, responsive nanoprobes, and theranostic nanotechnologies to provide solutions for current challenges in the diagnosis and treatment of diseases. His research has been published in high impact journals, such as Nature Photonics, Journal of the American Chemical Society (JACS), Angewandte Chemie, ACS Nano, Advanced Science, Small, Biomaterials, and Analytical Chemistry. He has published over 80 research papers since his first publication in 2010 (> 40 papers published as first/corresponding author), and 1 patent.

Service: Dr Zhang has been an Editor of 7 international jouranls, and is currently a Guest Editor of Methods (Elsevier), Nanomaterials, Molecules, and Materials. He is a referee for >70 journals, ARC (FT, DECRA, DP, LIEF, and LP) and NHMRC grant.

Research Interests

  • Biosensors to probe highly reactive biomolecules
    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.
  • Bionanoprobes for deep tissue imaging
    fabrication of responsive Ln-doped nanomaterials for imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.
  • Chemosensors for the detection of environmental pollutants
    development of ultra-sensitive chemosensors for the detection of heavy metals, toxic anions and gases.
  • Time-gated luminescence bioassay
    development of novel luminescent probes with long emission lifetime to remove autofluorescence, allowing background-free sensing and bioimaging.
  • Functional nanomaterial for tumour early diagnosis and imaging guided tumour therapy
    including photodynamic therapy (PDT), and chemotherapy

Qualifications

  • Doctor of Engineering, Dalian University of Technology (PRC)

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Available Projects

View all Available Projects

Publications

Journal Article

Conference Publication

  • Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. In: Hutchinson, MR and Goldys, EM, Spie Biophotonics Australasia. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, (). 17 - 19 October 2016. doi:10.1117/12.2242978

  • Zhao, Jiangbo, Zheng, Xianlin, Schartner, Erik P., Ionescu, Paul, Zhang, Run, Nguyen, Tich-Lam, Jin, Dayong and Ebendorff-Heidepriem, Heike (2016). Upconversion nanocrystals doped glass: a new paradigm for integrated optical glass. In: Photonics and Fiber Technology 2016 (ACOFT, BGPP, NP). Photonics and Fiber Technology , Sydney, Australia, (). 5–8 September 2016. doi:10.1364/acoft.2016.am5c.7

  • Zhang, Peng, Ruan, Shuai, Zhang, Run, Pullen, Benjamin, Zhang, Xiaozhou, Purdey, Malcolm Stuart, Ebendorff-Heidepriem, Heike, Abell, Andrew, Ding, Liyun, Tang, Ming and Ruan, Yinlan (2014). Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex. In: Asia-Pacific Optical Sensors Conference, APOS 2016. Asia-Pacific Optical Sensors Conference, APOS 2016, Shanghai China, (). 11-14 October 2016. doi:10.1364/APOS.2016.W3A.5

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.