Professor Michael O'Sullivan


UQ Centre for Clinical Research
Faculty of Medicine



Professor O’Sullivan holds a joint appointment as a Professor of Neuroscience at QBI and as Director of the Mater (clinical) Centre for Neuroscience. Professor O’Sullivan is an eminent neurologist with extensive clinical research experience. He will be integral in establishing the clinical interface between QBI clinicians, researchers, and the wider community. Previously, Professor O’Sullivan has been the strategic lead for stroke at King’s Health Partners, an Academic Health Sciences Centre connecting the University and three major NHS Foundation Trusts in South London. Professor O’Sullivan has substantial experience in the application of diffusion MRI, tractography and functional MRI to understand the interaction between focal damage and other processes involved in ageing and early cognitive decline, viewed from a network perspective.


Professor O’Sullivan has examined PhD theses for the University of London, University of Toronto, and Erasmus University Rotterdam. He currently supervises 3 PhD/MD students, and 2 PhD students have successfully completed their doctorate under his supervision.

Research Impacts

With significant clinical experience, Professor O’Sullivan’s research focus is translational in nature, promoting the restoration of function. His previous work has been aimed at identifying mechanisms of resilience and restoration of function that can be targeted by therapies that promote recovery; the STRATEGIC study targets such mechanistic insights in stroke. Professor O’Sullivan has consulted in numerous UK clinics and hospitals with a focus on hyperacute stroke services, microvascular disease and genetic forms, and post-stroke cognitive impairment and dementia.


  • Evans, Tavia E., Adams, Hieab H. H., Licher, Silvan, Wolters, Frank J., van der Lugt, Aad, Ikram, M. Kamran, O'Sullivan, Michael J., Vernooij, Meike W. and Ikram, M. Arfan (2018) Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia. NeuroImage, 178 129-135. doi:10.1016/j.neuroimage.2018.05.041

  • Horsburgh, Karen, Wardlaw, Joanna M., van Agtmael, Tom, Allan, Stuart M., Ashford, Mike L.J., Bath, Philip M., Brown, Rosalind, Berwick, Jason, Cader, M. Zameel, Carare, Roxana O., Davis, John B., Duncombe, Jessica, Farr, Tracy D., Fowler, Jill H., Goense, Jozien, Granata, Alessandra, Hall, Catherine N., Hainsworth, Atticus H., Harvey, Adam, Hawkes, Cheryl A., Joutel, Anne, Kalaria, Rajesh N., Kehoe, Patrick G., Lawrence, Catherine B., Lockhart, Andy, Love, Seth, Macleod, Malcolm R., Macrae, I. Mhairi, Markus, Hugh S., McCabe, Chris, McColl, Barry W., Meakin, Paul J., Miller, Alyson, Nedergaard, Maiken, O'Sullivan, Michael, Quinn, Terry J., Rajani, Rikesh, Saksida, Lisa M., Smith, Colin, Smith, Kenneth J., Touyz, Rhian M., Trueman, Rebecca C., Wang, Tao, Williams, Anna, Williams, Steven C.R. and Work, Lorraine M. (2018) Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. Clinical Science, 132 8: 851-868. doi:10.1042/CS20171620

  • Berlot, Rok and O'Sullivan, Michael J. (2017) What can the topology of white matter structural networks tell us about mild cognitive impairment?. Future Neurology, 12 1: 35-50. doi:10.2217/fnl-2016-0022

View all Publications


View all Grants


  • Doctor Philosophy

View all Supervision


Journal Article

Conference Publication

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Associate Advisor