Journal Article: ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription
Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y
Journal Article: LONP-1 aids propagation of deleterious mtDNA
Kirmes, Ina and Zuryn, Steven (2022). LONP-1 aids propagation of deleterious mtDNA. Nature Cell Biology, 24 (2), 127-128. doi: 10.1038/s41556-021-00838-z
Stamm, Paul, Kirmes, Ina, Palmer, Alexander, Molitor, Michael, Kvandova, Miroslava, Kalinovic, Sanela, Mihalikova, Dominika, Reid, George, Wenzel, Philip, Münzel, Thomas, Daiber, Andreas and Jansen, Thomas (2021). Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function. Life Sciences, 284 119879, 119879. doi: 10.1016/j.lfs.2021.119879
Metabolic and molecular protection against mtDNA mutations
(2022–2025) NHMRC IDEAS Grants
Mitochondrial DNA damage in neurons: Protective responses that preserve neural functions
Doctor Philosophy
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription
Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y
LONP-1 aids propagation of deleterious mtDNA
Kirmes, Ina and Zuryn, Steven (2022). LONP-1 aids propagation of deleterious mtDNA. Nature Cell Biology, 24 (2), 127-128. doi: 10.1038/s41556-021-00838-z
Stamm, Paul, Kirmes, Ina, Palmer, Alexander, Molitor, Michael, Kvandova, Miroslava, Kalinovic, Sanela, Mihalikova, Dominika, Reid, George, Wenzel, Philip, Münzel, Thomas, Daiber, Andreas and Jansen, Thomas (2021). Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function. Life Sciences, 284 119879, 119879. doi: 10.1016/j.lfs.2021.119879
PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome
Ahier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Cummins, Nadia, Hung, Grace Ching Ching, Götz, Jürgen and Zuryn, Steven (2021). PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome. Cell Reports, 35 (9) 109203, 109203. doi: 10.1016/j.celrep.2021.109203
Ahier, Arnaud, Dai, Chuan-Yang, Tweedie, Andrea, Bezawork-Geleta, Ayenachew, Kirmes, Ina and Zuryn, Steven (2018). Publisher Correction: affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism. Nature cell biology, 20 (3), 361-361. doi: 10.1038/s41556-018-0055-x
Ahier, Arnaud, Dai, Chuan-Yang, Tweedie, Andrea, Bezawork-Geleta, Ayenachew, Kirmes, Ina and Zuryn, Steven (2018). Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism. Nature Cell Biology, 20 (3), 352-360. doi: 10.1038/s41556-017-0023-x
A transient ischemic environment induces reversible compaction of chromatin
Kirmes, Ina, Szczurek, Aleksander, Prakash, Kirti, Charapitsa, Iryna, Heiser, Christina, Musheev, Michael, Schock, Florian, Fornalczyk, Karolina, Ma, Dongyu, Birk, Udo, Cremer, Christoph and Reid, George (2015). A transient ischemic environment induces reversible compaction of chromatin. Genome Biology, 16 (1) 246. doi: 10.1186/s13059-015-0802-2
Metabolic and molecular protection against mtDNA mutations
(2022–2025) NHMRC IDEAS Grants
Mitochondrial DNA damage in neurons: Protective responses that preserve neural functions
Doctor Philosophy — Associate Advisor
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