Professor Stephen Mahler

Senior Group Leader

Australian Institute for Bioengineering and Nanotechnology
S.Mahler@eng.uq.edu.au
+61 7 334 63175
+61 7 336 54172

Overview

Professor Stephen Mahler is a Senior Group Leader at the Australian Institute for Bioengineering and Nanotechnology and Director of the Australian Research Council Training Centre for Biopharmaceutical Innovation (CBI), University of Queensland. Professor Mahler is a biotechnologist with a focus on R&D of recombinant-DNA derived protein biopharmaceuticals, drug delivery systems and nanomedicines. Professor Mahler has a record of translational research success and engages extensively with industry associated with the biomedical sciences both nationally and internationally.

Research within CBI covers three thematic research areas; discovery of new biopharmaceuticals, engineering cells for production of protein-based biopharmaceuticals and advanced manufacturing for industrial production. A current research interest is at the interface of the life sciences and materials science, using a synthetic biology approach for creating novel therapeutic entities as well as new systems for drug delivery.

Professor Mahler has a strong interest in education and training and was formerly Head of the Chemical and Biological Engineering Plan at the University of Queensland (2010-2016). Other educational initiatives include development of Masters Programs and a Continuing Professional Development program in the area of biopharmaceuticals. The CPD program is available to stakeholders in the industry, both in Australia and internationally.

Research Impacts

Professor Mahler has a strong engagement with industry both nationally and internationally, that through collaborative research has led to some significant translational outcomes including clinical trial of biopharmaceutical drug candidates through to approval. The Australian Research Council Training Centre for Biopharmaceutical Innovation is a consortium of partners including government, the University of Queensland and several industry partners, with a goal of contributing to the transformation of the biopharmaceutical industry. Through the Centre and the CPD Program in Biopharmaceuticals, Professor Mahler continues to work with stakeholders to ensure a vibrant future for the biopharmaceutical industry in Australia.

Qualifications

  • Doctor of Philosophy, The University of Queensland

Publications

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Grants

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Supervision

View all Supervision

Publications

Book Chapter

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2016). Interleukin-12/23 Inhibitors: Ustekinumab. In Encyclopedia of Inflammatory Diseases (pp. 1-3) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_232-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). CD20 Inhibitors: Rituximab. In Encyclopedia of Inflammatory Diseases (pp. 1-4) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_21-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). CD80/CD86 Inhibitors. In Encyclopedia of Inflammatory Diseases (pp. 1-4) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_20-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Disease-Modifying Anti-Rheumatic Drugs. In Encyclopedia of Inflammatory Diseases (pp. 1-13) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_48-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Interleukin 1 Inhibitors. In Encyclopedia of Inflammatory Diseases (pp. 1-5) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_29-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Interleukin-6 Inhibitor – Tocilizumab. In Encyclopedia of Inflammatory Diseases (pp. 1-5) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_231-1

  • Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). TNF Inhibitors. In Encyclopedia of Inflammatory Diseases (pp. 1-10) Basel Switzerland: Springer. doi:10.1007/978-3-0348-0620-6_67-1

  • Nouwens, Amanda and Mahler, Stephen (2012). Evolution of proteomic methods for analysis of complex biological samples - implications for personalized medicine.. In Hon-Chiu Eastwood Leung, Tsz-Kwong Man and Ricardo J. Flores (Ed.), Integrative Proteomics (pp. 29-43) Croatia: InTech. doi:10.5772/29613

  • Pile, Kevin D., Graham, Garry G., Mahler, Stephen M. and Day, Richard O. (2011). Disease-modifying antirheumatic drugs. In Frans P. Nijkamp and Michael J. Parnham (Ed.), Principles of immunopharmacology 3rd ed. (pp. 585-619) Basel, Switzerland: Springer. doi:10.1007/978-3-0346-0136-8_30

  • Mahler, S. M. (1995). Downstream processing of monoclonal antibodies produced by cell culture techniques. In J. P. Barford, C. Harbour, C. P. Marquis, R. Malik, S. Mahler and P. J. Phillips (Ed.), Fundamental and applied aspects of animal cell culture (pp. 197-232) Singapore: Singapore University Press.

  • Mahler, Stephen M. (1990). Protein engineering and diagnostic techniques. In Pauline M. Doran (Ed.), Directions in Modern Biotechnology (pp. 51-71) Melbourne, VIC, Australia: Hawker Brownlow Education.

Journal Article

Conference Publication

Other Outputs

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision