The University of Queensland

Disease-modifying anti-rheumatic drugs

Pile, Kevin D., Graham, Garry G., Mahler, Stephen M. and Day, Richard O. (2019). Disease-modifying anti-rheumatic drugs. Nijkamp and Parnham’s principles of immunopharmacology. (pp. 709-750) edited by Michael J. Parnham, Frans P. Nijkamp and Adriano G. Rossi. Cham, Switzerland: Springer. doi: 10.1007/978-3-030-10811-3_34

Selection of antibodies to transiently expressed membrane proteins using phage display

Jones, Martina L., Mahler, Stephen M. and Kumble, Sumukh (2018). Selection of antibodies to transiently expressed membrane proteins using phage display. Antibody engineering. (pp. 179-195) edited by Damien Nevoltris and Patrick Chames. New York, NY, United States: Springer. doi: 10.1007/978-1-4939-8648-4_10

Interleukin-12/23 Inhibitors: Ustekinumab

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2016). Interleukin-12/23 Inhibitors: Ustekinumab. Encyclopedia of Inflammatory Diseases. (pp. 1-3) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_232-1

CD20 Inhibitors: Rituximab

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). CD20 Inhibitors: Rituximab. Encyclopedia of Inflammatory Diseases. (pp. 1-4) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_21-1

CD80/CD86 Inhibitors

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). CD80/CD86 Inhibitors. Encyclopedia of Inflammatory Diseases. (pp. 1-4) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_20-1

Disease-Modifying Anti-Rheumatic Drugs

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Disease-Modifying Anti-Rheumatic Drugs. Encyclopedia of Inflammatory Diseases. (pp. 1-13) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_48-1

Interleukin 1 Inhibitors

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Interleukin 1 Inhibitors. Encyclopedia of Inflammatory Diseases. (pp. 1-5) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_29-1

Interleukin-6 Inhibitor – Tocilizumab

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). Interleukin-6 Inhibitor – Tocilizumab. Encyclopedia of Inflammatory Diseases. (pp. 1-5) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_231-1

TNF Inhibitors

Pile, Kevin D., Graham, Garry G. and Mahler, Stephen M. (2015). TNF Inhibitors. Encyclopedia of Inflammatory Diseases. (pp. 1-10) edited by Michael J. Parnham. Basel Switzerland: Springer. doi: 10.1007/978-3-0348-0620-6_67-1

Evolution of proteomic methods for analysis of complex biological samples - implications for personalized medicine.

Nouwens, Amanda and Mahler, Stephen (2012). Evolution of proteomic methods for analysis of complex biological samples - implications for personalized medicine.. Integrative Proteomics. (pp. 29-43) edited by Hon-Chiu Eastwood Leung, Tsz-Kwong Man and Ricardo J. Flores. Croatia: InTech. doi: 10.5772/29613

C15 disease-modifying antirheumatic drugs

Pile, Kevin D., Graham, Garry G., Mahler, Stephen M. and Day, Richard O. (2011). C15 disease-modifying antirheumatic drugs. Principles of immunopharmacology. (pp. 585-619) edited by Frans P. Nijkamp and Michael J. Parnham. Basel, Switzerland: Springer. doi: 10.1007/978-3-0346-0136-8_30

Downstream processing of monoclonal antibodies produced by cell culture techniques

Mahler, S. M. (1995). Downstream processing of monoclonal antibodies produced by cell culture techniques. Fundamental and applied aspects of animal cell culture. (pp. 197-232) edited by J. P. Barford, C. Harbour, C. P. Marquis, R. Malik, S. Mahler and P. J. Phillips. Singapore: Singapore University Press.

Protein engineering and diagnostic techniques

Mahler, Stephen M. (1990). Protein engineering and diagnostic techniques. Directions in Modern Biotechnology. (pp. 51-71) edited by Pauline M. Doran. Melbourne, VIC, Australia: Hawker Brownlow Education.

Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies

Islam, Jiaul, Conroy, Paul, Fercher, Christian, Kim, Mijin, Yaari, Zvi, Jones, Martina, Bell, Toby D. M., Caradoc-Davies, Tom, Law, Ruby, Whisstock, James, Heller, Daniel, Mahler, Stephen and Corrie, Simon (2023). Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies. ACS Chemical Biology, 18 (8), 1863-1871. doi: 10.1021/acschembio.3c00303

Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies

Panagides, Nadya, Zacchi, Lucia F., Souza, Mitchell J. De, Morales, Rodrigo A. V., Karnowski, Alexander, Liddament, Mark T., Owczarek, Catherine M., Mahler, Stephen M., Panousis, Con, Jones, Martina L. and Fercher, Christian (2022). Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies. International Journal of Molecular Sciences, 23 (15) 8470, 8470. doi: 10.3390/ijms23158470

Engineering death resistance in CHO cells for improved perfusion culture

MacDonald, Michael A., Nöbel, Matthias, Martínez, Verónica S., Baker, Kym, Shave, Evan, Gray, Peter P., Mahler, Stephen, Munro, Trent, Nielsen, Lars K. and Marcellin, Esteban (2022). Engineering death resistance in CHO cells for improved perfusion culture. mAbs, 14 (1) e2083465, 1-13. doi: 10.1080/19420862.2022.2083465

Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption

Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416

Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok

MacDonald, Michael A., Barry, Craig, Groves, Teddy, Martínez, Verónica S., Gray, Peter P., Baker, Kym, Shave, Evan, Mahler, Stephen, Munro, Trent, Marcellin, Esteban and Nielsen, Lars K. (2022). Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok. Biotechnology and Bioengineering, 119 (6), 1380-1391. doi: 10.1002/bit.28062

Disulfide bond engineering of AppA phytase for increased thermostability requires co-expression of protein disulfide isomerase in Pichia pastoris

Navone, Laura, Vogl, Thomas, Luangthongkam, Pawarisa, Blinco, Jo-Anne, Luna-Flores, Carlos H., Chen, Xiaojing, von Hellens, Juhani, Mahler, Stephen and Speight, Robert (2021). Disulfide bond engineering of AppA phytase for increased thermostability requires co-expression of protein disulfide isomerase in Pichia pastoris. Biotechnology for Biofuels, 14 (1) 80, 80. doi: 10.1186/s13068-021-01936-8

In silico molecular dynamics of human glycophorin A (GPA) extracellular structure

Ekman, Serena, Flower, Robert, Mahler, Stephen, Gould, Alison, Barnard, Ross T., Hyland, Catherine, Jones, Martina, Malde, Alpeshkumar K. and Bui, Xuan T. (2021). In silico molecular dynamics of human glycophorin A (GPA) extracellular structure. Annals of Blood, 6 (June) 11. doi: 10.21037/aob-20-51

Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product

Zacchi, Lucia F., Roche-Recinos, Dinora, Pegg, Cassandra L., Phung, Toan K., Napoli, Mark, Aitken, Campbell, Sandford, Vanessa, Mahler, Stephen M., Lee, Yih Yean, Schulz, Benjamin L. and Howard, Christopher B. (2021). Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product. Communications Biology, 4 (1) 390, 390. doi: 10.1038/s42003-021-01903-x

Recombinant antibody engineering enables reversible binding for continuous protein biosensing

Fercher, Christian, Jones, Martina L., Mahler, Stephen M. and Corrie, Simon R (2021). Recombinant antibody engineering enables reversible binding for continuous protein biosensing. ACS Sensors, 6 (3) acssensors.0c01510, 764-776. doi: 10.1021/acssensors.0c01510

Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugate

Wardiana, Andri, Jones, Martina L., Mahler, Stephen M. and Howard, Christopher B. (2021). Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugate. Indonesian Journal of Pharmacy, 32 (1), 96-105. doi: 10.22146/ijp.1101

Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications

MacDonald, Michael A., Nöbel, Matthias, Roche Recinos, Dinora, Martínez, Verónica S., Schulz, Benjamin L., Howard, Christopher B., Baker, Kym, Shave, Evan, Lee, Yih Yean, Marcellin, Esteban, Mahler, Stephen, Nielsen, Lars Keld and Munro, Trent (2021). Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications. Critical Reviews in Biotechnology, 42 (7), 1-17. doi: 10.1080/07388551.2021.1998821

A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells

Lund, Maria E., Howard, Christopher B., Thurecht, Kristofer J., Campbell, Douglas H., Mahler, Stephen M. and Walsh, Bradley J. (2020). A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer, 20 (1) 1214, 1214. doi: 10.1186/s12885-020-07562-1

Aggregates in blood filter chambers used from the plasma donations of anti-D donors: evaluation for monoclonal antibody discovery using phage display

McGowan, Eunike C., Flower, Robert L., Jones, Martina L., Irving, David O., Barnard, Ross T., Hyland, Catherine A., Mahler, Stephen M. and Bui, Xuan T. (2020). Aggregates in blood filter chambers used from the plasma donations of anti-D donors: evaluation for monoclonal antibody discovery using phage display. Blood Transfusion , 19 (1), 64-72. doi: 10.2450/2020.0093-20

Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting

Sivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033

‘Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells

Orellana, Camila A., Martínez, Verónica S., MacDonald, Michael A., Henry, Matthew N., Gillard, Marianne, Gray, Peter P., Nielsen, Lars K., Mahler, Stephen and Marcellin, Esteban (2020). ‘Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells. Biotechnology and Bioengineering, 118 (1) bit.27548, 481-490. doi: 10.1002/bit.27548

Phage display derived monoclonal antibodies: from bench to bedside

Alfaleh, Mohamed A., Alsaab, Hashem O., Mahmoud, Ahmad Bakur, Alkayyal, Almohanad A., Jones, Martina L., Mahler, Stephen M. and Hashem, Anwar M. (2020). Phage display derived monoclonal antibodies: from bench to bedside. Frontiers in Immunology, 11 1986, 1986. doi: 10.3389/fimmu.2020.01986

Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets

Niamsuphap, Suchada, Fercher, Christian, Kumble, Sumukh, Huda, Pie, Mahler, Stephen M. and Howard, Christopher B. (2020). Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets. Expert Opinion on Drug Delivery, 17 (9), 1189-1211. doi: 10.1080/17425247.2020.1781088

Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies

Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299

Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

Playford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6

Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production

Henry, Matthew N., MacDonald, Michael A., Orellana, Camila A., Gray, Peter P., Gillard, Marianne, Baker, Kym, Nielsen, Lars K., Marcellin, Esteban, Mahler, Stephen and Martinez, Veronica S. (2020). Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production. Biotechnology and Bioengineering, 117 (4) bit.27269, 1187-1203. doi: 10.1002/bit.27269

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing

Raftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g

Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy

Tang, Jie, Li, Bei, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Wu, Yilun, Huang, Leaf and Xu, Zhi Ping (2019). Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials, 216 119232, 119232. doi: 10.1016/j.biomaterials.2019.119232

Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments

Islam, Jiaul, Riley, Blake T., Fercher, Christian, Jones, Martina L., Buckle, Ashley M., Howard, Christopher B., Cox, Rosalind P., Bell, Toby D. M., Mahler, Stephen and Corrie, Simon R. (2019). Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments. Analytical Chemistry, 91 (12), 7631-7638. doi: 10.1021/acs.analchem.9b00445

Innovative therapeutic strategies for effective treatment of brain metastases

Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280. doi: 10.3390/ijms20061280

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning

Alfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015

Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments

Li, Junrong, Wang, Jing, Grewal, Yadveer S, Howard, Christopher B, Raftery, Lyndon J, Mahler, Stephen, Wang, Yuling and Trau, Matt (2018). Multiplexed SERS detection of soluble cancer protein biomarkers with gold-silver alloy nanoboxes and nanoyeast single-chain variable fragments. Analytical Chemistry, 90 (17) acs.analchem.8b02216, 10377-10384. doi: 10.1021/acs.analchem.8b02216

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models

Alfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu and Mahler, Stephen M. (2017). Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models. Plos One, 12 (10) e0186137, e0186137. doi: 10.1371/journal.pone.0186137

Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions

Tayeb, Hossam H, Piantavigna, Stefania, Howard, Christopher B, Nouwens, Amanda, Mahler, Stephen M, Middelberg, Anton P J, He, Lizhong, Holt, Stephen A and Sainsbury, Frank (2017). Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions. Soft matter, 13 (43), 7953-7961. doi: 10.1039/c7sm01614j

Cell-free pipeline for discovery of thermotolerant xylanases and endo-1,4-β-glucanases

Gagoski, Dejan, Shi, Zhenyu, Nielsen, Lars Keld, Vickers, Claudia E., Mahler, Stephen, Speight, Robert, Johnston, Wayne A. and Alexandrov, Kirill (2017). Cell-free pipeline for discovery of thermotolerant xylanases and endo-1,4-β-glucanases. Journal of Biotechnology, 259, 191-198. doi: 10.1016/j.jbiotec.2017.07.014

Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning

Alfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B. and Mahler, Stephen M. (2017). Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning. Antibodies, 6 (3) 10, 1-19. doi: 10.3390/antib6030010

Safety of biologics therapy: monoclonal antibodies, cytokines, fusion proteins, hormones, enzymes, coagulation proteins, vaccines, botulinum toxins

Mahler, Stephen (2017). Safety of biologics therapy: monoclonal antibodies, cytokines, fusion proteins, hormones, enzymes, coagulation proteins, vaccines, botulinum toxins. mAbs, 9 (6), 885-888. doi: 10.1080/19420862.2017.1343709

Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay

Lebani, Kebaneilwe, Jones, Martina L., Watterson, Daniel, Ranzoni, Andrea, Traves, Renee J., Young, Paul R. and Mahler, Stephen M. (2017). Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay. PLoS One, 12 (7) e0180669, e0180669. doi: 10.1371/journal.pone.0180669

Computational identification of antibody epitopes on the dengue virus NS1 protein

Jones, Martina L., Legge, Fiona S., Lebani, Kebaneilwe, Mahler, Stephen M., Young, Paul R., Watterson, Daniel, Treutlein, Herbert R. and Zeng, Jun (2017). Computational identification of antibody epitopes on the dengue virus NS1 protein. Molecules, 22 (4) 607, 607. doi: 10.3390/molecules22040607

Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10

Alsultan, Abdulkarim M., Chin, David Y., Howard, Christopher B., de Bakker, Christopher J., Jones, Martina L. and Mahler, Stephen M. (2016). Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10. Scientific Reports, 5 (37348) 37348, 37348. doi: 10.1038/srep37348

Nanoyeast and other cell envelope compositions for protein studies and biosensor applications

Grewal, Yadveer S., Shiddiky, Muhammad J. A., Mahler, Stephen M., Cangelosi, Gerard A. and Trau, Matt (2016). Nanoyeast and other cell envelope compositions for protein studies and biosensor applications. ACS Applied Materials and Interfaces, 8 (45), 30649-30664. doi: 10.1021/acsami.6b09263

Biosimilars approved for treatment of inflammatory rheumatological diseases

Mahler, Stephen M., Wardiana, Andri, Jones, Martina L., De Bakker, Christopher J., Graham, Garry G. and Howard, Christopher B. (2016). Biosimilars approved for treatment of inflammatory rheumatological diseases. International Journal of Rheumatic Diseases, 19 (11), 1043-1048. doi: 10.1111/1756-185X.13037

Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016)

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016). Advanced Healthcare Materials, 5 (16), 1994-1994. doi: 10.1002/adhm.201670084

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263

Targeting membrane proteins for antibody discovery using phage display

Jones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y. and Mahler, Stephen M. (2016). Targeting membrane proteins for antibody discovery using phage display. Scientific Reports, 6 (1) 26240, 26240. doi: 10.1038/srep26240

CMRF-56+ blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T lymphocyte responses

Fromm, Phillip D., Papadimitrious, Michael S., Hsu, Jennifer L., Van Kooten Losio, Nicolas, Verma, Nirupama D., Lo, Tsun Ho, Silveira, Pablo A., Bryant, Christian E., Turtle, Cameron J., Prue, Rebecca L., Vukovic, Peter, Munster, David J., Nagasaki, Tomoko, Barnard, Ross T., Mahler, Stephen M., Anguille, Sébastien A., Berneman, Zwi, Horvath, Lisa G., Bradstock, Kenneth F., Joshua, Douglas E., Clark, Georgina J. and Hart, Derek N. J. (2016). CMRF-56+ blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T lymphocyte responses. OncoImmunology, 5 (6) e1168555, e1168555. doi: 10.1080/2162402X.2016.1168555

Biosensing made easy with PEG-targeted bi-specific antibodies

Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A

Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation.

Seldon, T. A., Pryor, R., Palkova, A., Jones, M. L., Verma, N. D., Findova, M., Braet, K., Sheng, Y., Fan, Y., Zhou, Y. Y., Marks, J. D., Munro, T., Mahler, S. M., Barnard, R. T., Fromm, P. D., Silveira, P. A., Elgundi, Z., Ju, X., Clark, G. J., Bradstock, K. F., Munster, D. J. and Hart, D. N. J. (2015). Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation.. Leukemia, 30 (3), 692-700. doi: 10.1038/leu.2015.231

Effect of energy source, salt concentration and loading force on colloidal interactions between Acidithiobacillus ferrooxidans cells and mineral surfaces

Diao, Mengxue, Nguyen, Tuan A.H., Taran, Elena, Mahler, Stephen M. and Nguyen, Anh V. (2015). Effect of energy source, salt concentration and loading force on colloidal interactions between Acidithiobacillus ferrooxidans cells and mineral surfaces. Colloids and Surfaces B: Biointerfaces, 132, 271-280. doi: 10.1016/j.colsurfb.2015.05.026

Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells

Tang, Jie, Li, Li, Howard, Christopher B., Mahler, Stephen M., Huang, Leaf and Xu, Zhi Ping (2015). Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells. Journal of Materials Chemistry B, 3 (33), 6805-6812. doi: 10.1039/c5tb00912j

Advances in drug delivery

Mahler, Stephen and Roy, Ipsita (2015). Advances in drug delivery. Journal of Chemical Technology and Biotechnology, 90 (7), 1167-1168. doi: 10.1002/jctb.4689

Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease

Naylor, Dean J., Hunt, Ben, Guidolin, Angelo, Hey, Allan W., Bastiras, Stan, de Bakker, Christopher J., Chin, David Y., Marquis, Christopher P., Lambert, Daniel, Howard, Christopher B., Dobbin, Caroline A. and Mahler, Stephen M. (2015). Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease. Process Biochemistry, 50 (10) 10466, 1669-1679. doi: 10.1016/j.procbio.2015.06.022

Nanocell targeting using engineered bispecific antibodies.

Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952

Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy - future prospects

Goodall, Stephen, Jones, Martina L. and Mahler, Stephen (2014). Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy - future prospects. Journal of Chemical Technology and Biotechnology, 90 (7), 1169-1176. doi: 10.1002/jctb.4555

Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells

Buecheler, Jakob W., Howard, Christopher B., de Bakker, Christopher J., Goodall, Stephen, Jones, Martina L, Win, Thinzar, Peng, Tao, Tan, Cher Heng, Chopra, Akhil, Mahler, Stephen M and Lim, Sierin (2014). Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells. Journal of Chemical Technology and Biotechnology, 90 (7), 1230-1236. doi: 10.1002/jctb.4545

A concise review of nanoscopic aspects of bioleaching bacteria-mineral interactions

Diao, Mengxue, Taran, Elena, Mahler, Stephen and Nguyen, Anh V. (2014). A concise review of nanoscopic aspects of bioleaching bacteria-mineral interactions. Advances in Colloid and Interface Science, 212, 45-63. doi: 10.1016/j.cis.2014.08.005

An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer

Goodall, Stephen, Howard, Christopher B., Jones, Martina L., Munro,Trent, Jia, Zhongfan, Monteiro, Michael J and Mahler, Stephen (2014). An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer. Journal of Chemical Technology and Biotechnology, 90 (7), 1222-1229. doi: 10.1002/jctb.4509

Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2

Leow, Chiuan Herng, Jones, Martina, Cheng, Qin, Mahler, Strphen and McCarthy, James (2014). Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2. Malaria Journal, 13 (1) 277. doi: 10.1186/1475-2875-13-277

Differences in adhesion of A. thiooxidans and A. ferrooxidans on chalcopyrite as revealed by atomic force microscopy with bacterial probes

Diao, Mengxue, Nguyen, Tuan A. H., Taran, Elena, Mahler, Stephen and Nguyen, Anh V. (2014). Differences in adhesion of A. thiooxidans and A. ferrooxidans on chalcopyrite as revealed by atomic force microscopy with bacterial probes. Minerals Engineering, 61, 9-15. doi: 10.1016/j.mineng.2014.03.002

Quantifying adhesion of acidophilic bioleaching bacteria to silica and pyrite by atomic force microscopy with a bacterial probe

Diao, Mengxue, Taran, Elena, Mahler, Stephen, Nguyen, Tuan A. H. and Nguyen, Anh V. (2014). Quantifying adhesion of acidophilic bioleaching bacteria to silica and pyrite by atomic force microscopy with a bacterial probe. Colloids and Surfaces B: Biointerfaces, 115, 229-236. doi: 10.1016/j.colsurfb.2013.11.047

Comparison and evaluation of immobilization methods for preparing bacterial probes using acidophilic bioleaching bacteria Acidithiobacillus thiooxidans for AFM studies

Diao, Mengxue, Taran, Elena, Mahler, Stephen M. and Nguyen, Anh V. (2014). Comparison and evaluation of immobilization methods for preparing bacterial probes using acidophilic bioleaching bacteria Acidithiobacillus thiooxidans for AFM studies. Journal of Microbiological Methods, 102, 12-14. doi: 10.1016/j.mimet.2014.04.004

Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates

Munro, Trent P., Mahler, Stephen M., Huang, Edwin P., Chin, David Y. and Gray, Peter P. (2011). Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates. mAbs, 3 (5), 440-452. doi: 10.4161/mabs.3.5.16968

Analytical strategies for assessing comparability of biosimilars

Falconer, Robert J., Jackson-Matthews, Dianne and Mahler, Stephen M. (2011). Analytical strategies for assessing comparability of biosimilars. Journal of Chemical Technology and Biotechnology, 86 (7), 915-922. doi: 10.1002/jctb.2629

Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening

Song, Michael, Raphaelli, Kristin, Jones, Martina L., Aliabadi-Zadeh, Khosrow, Leung, Kar Man, Crowley, David, Hughes, Benjamin, Mahler, Stephen, Gray, Peter P., Huang, Edwin P. and Chin, David Y. (2011). Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening. Journal of Chemical Technology and Biotechnology, 86 (7), 935-941. doi: 10.1002/jctb.2618

Biologics and biosimilars: emerging technologies driving global opportunity

Mahler, Stephen and Gray, Peter (2011). Biologics and biosimilars: emerging technologies driving global opportunity. Journal of Chemical Technology & Biotechnology, 86 (7), 893-894. doi: 10.1002/jctb.2684

Disease-specific, neurosphere-derived cells as models for brain disorders

Matigian, N, Abrahamsen, G, Sutharsan, R, Cook, AL, Vitale, AM, Nouwens, A, Bellette, B, An, JY, Anderson, M, Beckhouse, AG, Bennebroek, M, Cecil, R, Chalk, AM, Cochrane, J, Fan, YJ, Feron, F, McCurdy, R, McGrath, JJ, Murrell, W, Perry, C, Raju, J, Ravishankar, S, Silburn, PA, Sutherland, GT, Mahler, S, Mellick, GD, Wood, SA, Sue, CM, Wells, CA and Mackay-Sim, A (2010). Disease-specific, neurosphere-derived cells as models for brain disorders. Disease Models and Mechanisms, 3 (11-12), 785-798. doi: 10.1242/dmm.005447

A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies

Jones, Martina L., Seldon, Therese, Smede, Matthew, Linville, Ashleigh, Chin, David Y., Barnard, Ross, Mahler, Stephen M., Munster, David, Hart, Derek, Gray, Peter P. and Munro, Trent P. (2010). A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies. Journal of Immunological Methods, 354 (1-2), 85-90. doi: 10.1016/j.jim.2010.02.001

Evidence of heterogeneity in the antibody response against the platelet antigen 3a; recognition of an 11-mer peptide carrying the HPA-3a polymorphic determinant

de Leon, EJ, Yuan, FF, Pearson, H, Marquis, CP and Mahler, SM (2009). Evidence of heterogeneity in the antibody response against the platelet antigen 3a; recognition of an 11-mer peptide carrying the HPA-3a polymorphic determinant. VOX SANGUINIS, 96 (3), 252-255. doi: 10.1111/j.1423-0410.2008.01146.x

A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL

Wang, XS, Shao, BH, Oda, MN, Heinecke, JW, Mahler, S and Stocker, R (2009). A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL. JOURNAL OF LIPID RESEARCH, 50 (3), 586-594. doi: 10.1194/jlr.D800042-JLR200

BioPEGylation of Polyhydroxyalkanoates: Influence on Properties and Satellite-Stem Cell Cycle

Marcal, Helder, Wanandy, Nico S., Sanguanchaipaiwong, Vorapat, Woolnough, Catherine E., Lauto, Antonio, Mahler, Stephen M. and Foster, L. John R. (2008). BioPEGylation of Polyhydroxyalkanoates: Influence on Properties and Satellite-Stem Cell Cycle. Biomacromolecules, 9 (10), 2719-2726. doi: 10.1021/bm800418e

Expression proteomics of olfactory ensheathing cells

Marcal, Helder, Sarris, Maria, Raftery, Mark J., Bhasin, Vishal, McFarland, Clive and Mahler, Stephen M. (2008). Expression proteomics of olfactory ensheathing cells. Journal of Chemical Technology And Biotechnology, 83 (4), 473-481. doi: 10.1002/jctb.1900

In Focus: Stem cell and tissue engineering applications in regenerative medicine

Mahler, Stephen (2008). In Focus: Stem cell and tissue engineering applications in regenerative medicine. Journal of Chemical Technology and Biotechnology, 83 (4), 395-396. doi: 10.1002/jctb.1933

The macrophage-biomaterial interface: a proteomic analysis of the conditioned medium environment

Dinnes, Donna Lee M., Marcal, Helder, Raftery, Mark J., Labow, Rosalind S. and Mahler, Stephen M. (2008). The macrophage-biomaterial interface: a proteomic analysis of the conditioned medium environment. Journal of Chemical Technology And Biotechnology, 83 (4), 482-495. doi: 10.1002/jctb.1854

Cytotoxic activity of CD48 monoclonal antibodies against human lymphoma cells

Wei, Jiewei, Chin, David Y. and Mahler, Stephen M. (2008). Cytotoxic activity of CD48 monoclonal antibodies against human lymphoma cells. Open Biotechnology Journal, 2 (1), 219-223. doi: 10.2174/1874070700802010219

Practical blood dendritic cell vaccination for immunotherapy of multiple myeloma

Vari F, Munster D.J., Hsu J.L., Rossetti T.R., Stephen Mahler, Gray, Peter P., Turtle C.J., Prue R.L. and Hart D.N. (2008). Practical blood dendritic cell vaccination for immunotherapy of multiple myeloma. British Journal Of Haematology, 143 (3), 374-377. doi: 10.1111/j.1365-2141.2008.07346.x

Material surfaces affect the protein expression patterns of human macrophages: A proteomics approach

Mahler, Stephen Michael, Dinnes, Donna Lee M., Marçal, Helder, Santerre, J. Paul and Labow, Rosalind S. (2007). Material surfaces affect the protein expression patterns of human macrophages: A proteomics approach. Journal of Biomedical Materials Research Part A, 80A (4), 895-908. doi: 10.1002/jbm.a.30967

Fractionation of follicle stimulating hormone charge isoforms in their native form by preparative electrophoresis technology

Catzel, D., Chin, D. Y., Stanton, P. G., Gray, P. P. and Mahler, S. A. (2006). Fractionation of follicle stimulating hormone charge isoforms in their native form by preparative electrophoresis technology. Journal of Biotechnology, 122 (1), 73-85. doi: 10.1016/j.jbiotec.2005.08.026

Purification of monoclonal antibodies from cell culture supernatants by Gradiflow (TM) electrophoresis technology

Mahler, Stephen M., Leong, Sharon, Gilbert, Andrew, Yang, Fan, Gray, Peter, Van Dyk, Derek and Roeth, Philip (2006). Purification of monoclonal antibodies from cell culture supernatants by Gradiflow (TM) electrophoresis technology. Journal of Chemical Technology And Biotechnology, 81 (3), 445-453. doi: 10.1002/jctb.1426

Expression and characterisation of recombinant human CD48 and isolation of a human anti-CD48 monoclonal antibody by phage display

Wei, J. W., Chin, D. Y., Catzel, D., Pera, N. and Mahler, S. M. (2005). Expression and characterisation of recombinant human CD48 and isolation of a human anti-CD48 monoclonal antibody by phage display. Journal of Chemical Technology And Biotechnology, 80 (7), 782-795. doi: 10.1002/jctb.1238

Purification of Fab fragments from a monoclonal antibody papain digest by Gradiflow electrophoresis

Coleman, L. and Mahler, S. M. (2003). Purification of Fab fragments from a monoclonal antibody papain digest by Gradiflow electrophoresis. Protein Expression And Purification, 32 (2), 246-251. doi: 10.1016/j.pep.2003.07.005

Increase in synthesis of human monoclonal antibodies by transfected Sp2/0 myeloma mouse cell line under conditions of microgravity

Foster, L. J. R., Catzel, D., Atwa, S., Zarka, M. and Mahler, S. M. (2003). Increase in synthesis of human monoclonal antibodies by transfected Sp2/0 myeloma mouse cell line under conditions of microgravity. Biotechnology Letters, 25 (15), 1271-1274. doi: 10.1023/A:1025003800414

The application of emerging technologies in genomics and proteomics to drug development

Mahler, S. M., Chin, D. Y. and Van Dyk, D. D. (2003). The application of emerging technologies in genomics and proteomics to drug development. Journal of Pharmacy Practice and Research, 33 (1), 7-11.

Purification of recombinant human growth hormone from CHO cell culture supernatant by Gradiflow preparative electrophoresis technology

Catzel, D., Lalevski, H., Marquis, C. P., Gray, P. P., Van Dyk, D. and Mahler, S. M. (2003). Purification of recombinant human growth hormone from CHO cell culture supernatant by Gradiflow preparative electrophoresis technology. Protein Expression And Purification, 32 (1), 126-134. doi: 10.1016/j.pep.2003.07.002

Bleeding babies

Marquis, Christopher, Mahler, Stephen, Pearson, Helen and Barcho, Shane (2001, 04 01). Bleeding babies Australasian Science 37-39.

The effectiveness of different rat IgG subclasses as IgE-blocking antibodies in the Rat Basophil Leukemia cell model

Philips, J. R., Brouwer, W., Mahler, S., Ruhno, J., Collins, A. M. and Edwards, M. (1999). The effectiveness of different rat IgG subclasses as IgE-blocking antibodies in the Rat Basophil Leukemia cell model. Immunology and Cell Biology, 77 (2), 121-126. doi: 10.1046/j.1440-1711.1999.00801.x

Comparison of the efficiency of Moloney Murine Leukaemia Virus (M-MuLV) reverse transcriptase, RNase H--M-MuLV reverse transcriptase and Avian Myeloblastoma Leukaemia Virus (AMV) reverse transcriptase for the amplification of human immunoglobulin genes

Wong, L, Pearson, H, Fletcher, A, Marquis, CP and Mahler, S (1998). Comparison of the efficiency of Moloney Murine Leukaemia Virus (M-MuLV) reverse transcriptase, RNase H--M-MuLV reverse transcriptase and Avian Myeloblastoma Leukaemia Virus (AMV) reverse transcriptase for the amplification of human immunoglobulin genes. Biotechnology Techniques, 12 (6), 485-489. doi: 10.1023/A:1008871608947

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

Bootcov, MR, Bauskin, AR, Valenzuela, SM, Moore, AG, Bansal, M, He, XY, Zhang, HP, Donnellan, M, Mahler, S, Pryor, K, Walsh, BJ, Nicholson, RC, Fairlie, WD, Por, SB, Robbins, JM and Breit, SN (1997). MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proceedings of the National Academy of Sciences of the United States of America, 94 (21), 11514-11519. doi: 10.1073/pnas.94.21.11514

Expression of a recombinant single chain Fv antibody fragment in mammalian cells

Chotigeat, Wilaiwan and Mahler, Stephen M. (1997). Expression of a recombinant single chain Fv antibody fragment in mammalian cells. Journal of the Science Society of Thailand, 23 (3), 159-170. doi: 10.2306/scienceasia1513-1874.1997.23.159

Cloning and expression of human V-genes derived from phage display libraries as fully assembled human anti-TNF alpha monoclonal antibodies

Mahler, SM, Marquis, CP, Brown, G, Roberts, A and Hoogenboom, HR (1997). Cloning and expression of human V-genes derived from phage display libraries as fully assembled human anti-TNF alpha monoclonal antibodies. Immunotechnology, 3 (1), 31-43. doi: 10.1016/S1380-2933(96)00058-9

A Master's program in biopharmaceutical science

Neering, IR, Fryer, MW and Mahler, SM (1996). A Master's program in biopharmaceutical science. Australasian Biotechnology, 6 (5), 272-276.

Biological activity and metabolic clearance of recombinant human follicle stimulating hormone produced in Sp2/0 myeloma cells

Chin, C. K., Schofield, P. R., Robertson, D. M., Gray, P. P., Chotigeat, W. and Mahler, S. M. (1996). Biological activity and metabolic clearance of recombinant human follicle stimulating hormone produced in Sp2/0 myeloma cells. Cytotechnology, 21 (2), 171-182. doi: 10.1007/BF02215667

Guiding the Selection of Human-Antibodies From Phage Display Repertoires to a Single Epitope of An Antigen

Jespers, LS, Roberts, A, Mahler, SM, Winter, G and Hoogenboom, HR (1994). Guiding the Selection of Human-Antibodies From Phage Display Repertoires to a Single Epitope of An Antigen. Bio-Technology, 12 (9), 899-903. doi: 10.1038/nbt0994-899

Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase enzymes for hFSH produced by recombinant CHO cells

Chotigeat, W., Watanapokasin, Y., Mahler, S. M. and Gray, P. P. (1994). Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase enzymes for hFSH produced by recombinant CHO cells. Cytotechnology, 15 (1-3), 217-221. doi: 10.1007/BF00762396

Isoelectric Charge of Recombinant Human Follicle-Stimulating-Hormone Isoforms Determines Receptor Affinity and Invitro Bioactivity

Cerpapoljak, A, Bishop, LA, Hort, YJ, Chin, Ckh, Dekroon, R, Mahler, SM, Smith, GM, Stuart, MC and Schofield, PR (1993). Isoelectric Charge of Recombinant Human Follicle-Stimulating-Hormone Isoforms Determines Receptor Affinity and Invitro Bioactivity. Endocrinology, 132 (1), 351-356. doi: 10.1210/en.132.1.351

Mammalian cell culture at the University of New South Wales

Gray, P. P., Marsden, W. L., Crowley, J., Gebert, C., Jirasripongpun, K., Lovrecz, G., Mitchell, C. and Mahler, S. M. (1990). Mammalian cell culture at the University of New South Wales. Australian Journal of Biotechnology, 4 (2), 121-134.

Downstream processing of monoclonal antibodies

Gunnersen, J. M., Fowles, L. F., Snelgar, J. M., Mitchell, C. A., Patava, J. V., Osborne, K. J. and Mahler, S. M. (1989). Downstream processing of monoclonal antibodies. Australian Journal of Biotechnology, 3 (1), 69-71.

Desensitization of Adenylate-Cyclase and Cyclic-Amp Flux During the Early Stages of Liver-Regeneration

Mahler, SM and Wilce, PA (1988). Desensitization of Adenylate-Cyclase and Cyclic-Amp Flux During the Early Stages of Liver-Regeneration. Journal of Cellular Physiology, 136 (1), 88-94. doi: 10.1002/jcp.1041360111

Studies On Regenerating Liver and Hepatoma Plasma-Membranes .1. Lipid and Protein-Composition

Mahler, SM, Wilce, PA and Shanley, BC (1988). Studies On Regenerating Liver and Hepatoma Plasma-Membranes .1. Lipid and Protein-Composition. International Journal of Biochemistry, 20 (6), 605-&. doi: 10.1016/0020-711X(88)90100-0

Studies On Regenerating Liver and Hepatoma Plasma-Membranes .2. Membrane Fluidity and Enzyme-Activity

Mahler, SM, Wilce, PA and Shanley, BC (1988). Studies On Regenerating Liver and Hepatoma Plasma-Membranes .2. Membrane Fluidity and Enzyme-Activity. International Journal of Biochemistry, 20 (6), 613-619. doi: 10.1016/0020-711X(88)90101-2

Canine PET/CT imaging with 64Cu-nanomedicines

Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.

Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system

Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina and Bui, Xuan (2019). Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.353

In silico model for glycophorin a (GPA) structure

Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina, Treutlein, Herbert and Bui, Xuan (2019). In silico model for glycophorin a (GPA) structure. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.352

In silico modelling of glycophorin MNS system blood group antigens

Flower, R., Ekman, S., Mahler, S., Jones, M., Malde, A. K. and Bui, X. (2019). In silico modelling of glycophorin MNS system blood group antigens. In: ANZSBT, Perth, Australia, (24-25). 20-23 October 2019.

Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines

Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02

CD83 Expression On Human Immune Cells as a Target for Immunosuppression

Hart, D. N. J., Elgundi, Z., Ju Xinsheng, Verma, N. D., Silveira, P. A., Fromm, P. D., Alingcastre, R., Munster, D. J., Seldon, T. A., Sheng, Y., Jones, M. L., Munro, T. P., Mahler, S., Barnard, R. T., Vu, P. A., Lo, K., Shahin, K., Larsen, S., Bradstock, K. and Clark, G. J. (2015). CD83 Expression On Human Immune Cells as a Target for Immunosuppression. 33rd Annual Scientific Meeting of the Transplantation Society of Australia and new Zealand, Canberra, ACT Australia, 21-23 June 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/icb.2015.75

Characterisation of human CD83 expression on immune cells and their targeting with CD83 antibodies to prevent graft versus host disease in allogeneic haematopoietic cell transplantation

Hart, Derek N. J., Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Hsu, Blake, Munster, David J., Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Al, Lo, Tsun Ho, Shahin, Kifah, Larsen, Stephen Robert, Bradstock, Kenneth and Clark, Georgina (2015). Characterisation of human CD83 expression on immune cells and their targeting with CD83 antibodies to prevent graft versus host disease in allogeneic haematopoietic cell transplantation. 57th Annual Meeting of the American Society of Hematology, Orlando, FL, United States, 5-8 Dec 2015. WASHINGTON: AMER SOC HEMATOLOGY.

Human Cd83 Expression On Immune Cells Validates Anti-Cd83 Prophylaxis to Prevent Graft Versus Host Disease in Allogeneic Haematopoietic Cell Transplantation.

Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Munster, David, Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Ai, Lo, Tsun Ho, Shahin, Kifah, Clark, Georgina, Larsen, Stephen, Bradstock, Kenneth and Hart, Derek (2015). Human Cd83 Expression On Immune Cells Validates Anti-Cd83 Prophylaxis to Prevent Graft Versus Host Disease in Allogeneic Haematopoietic Cell Transplantation.. 14th Transplantation Science Symposium of the Transplantation-Society (TSS), Lorne, Australia, 11-13 November 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

The Human Monoclonal Antibody 3C12C, Targeting Activated Dendritic Cells Is a Potential New Immunosuppressive Agent

Verma, Nirupama D., Munster, David, Seldon, Therese, Sheng, Yong Hua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Phi Ai, Lo, Kevin, Shahin, Kifah, Elgundi, Zehra, Silveira, Pablo, Fromm, Phillip D., Clark, Georgina J., Larsen, Stephen, Bradstock, Kenneth and Hart, Derek N. J. (2015). The Human Monoclonal Antibody 3C12C, Targeting Activated Dendritic Cells Is a Potential New Immunosuppressive Agent. BMT Tandem Meetings, San Diego, CA United States, 11-15 February 2015. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.bbmt.2014.11.527

The Monoclonal Antibody 3C12C, Targeting CD83 Is a T Cell Sparing, Potential New Immunosuppressive Agent

Hart, D, Verma, N., Seldon, T, Sheng, Y., Pryor, R., Palkova, A., Findova, M., Jones, M., Munro, T., Mahler, S., Braet, K., Barnard, R., Marks, J., Coley, A., Fan, F., Zhou, Y., Vu, P, Lo, K., Shahin, K., Elgundi, Z., Silveira, P., Fromm, P., Clark, G., Larsen, S., Bradstock, K. and Munster, D. (2014). The Monoclonal Antibody 3C12C, Targeting CD83 Is a T Cell Sparing, Potential New Immunosuppressive Agent. 2014 World Transplant Congress, San Francicso Ca, 26 - 31 July 2014. Malden, MA United States: Wiley-Blackwell Publishing, Inc.. doi: 10.1111/ajt.12888

Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease

Hart, D, Seldon, T, Jones, M, Sheng, Y, Palkova, A, Cullup, H, Munro, T, Sinfield, L, Rice, AM, Wilson, J, Gray, P, Barnard, R, Mahler, S and Munster, D (2009). Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease. 51st Annual Meeting of the American Society of Hematology, New Orleans LA, 5-8 December 2009. Washington, D.C.: American Society of Hematology.

A CMRF-56 blood dendritic cell preparation loaded with control and tumour-associated antigens, for the immune therapy of multiple myeloma: Transition to a phase I clinical trial

Vari, F., Rossetti, T., Prue, R., Mahler, S. and Hart, D.N. (2006). A CMRF-56 blood dendritic cell preparation loaded with control and tumour-associated antigens, for the immune therapy of multiple myeloma: Transition to a phase I clinical trial. x, x, x. United Kingdom: Informa Healthcare.

Secretome analysis of olfactory ensheathing cells for use in tissue engineering and regenerative medicine applications

Marcal, H, Raftery, M, Sarris, M, Mcfarland, C, Milthorpe, BK, Bhasin, V, Mackay-Sim, A and Mahler, S (2006). Secretome analysis of olfactory ensheathing cells for use in tissue engineering and regenerative medicine applications. Unknown, unknown, Unknown. BETHESDA: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC.

Human-Antibodies Derived From Rodent Antibodies Via Epitope Imprinted Selection (eis)

Hoogenboom, HR, Jespers, L, Mahler, S, Roberts, AJ, Chiswell, DJ and Winter, G (1994). Human-Antibodies Derived From Rodent Antibodies Via Epitope Imprinted Selection (eis). NEW YORK: WILEY-LISS.

Role of Environmental-Conditions On the Expression Levels, Glycoform Pattern and Levels of Sialyltransferase for Hfsh Produced by Recombinant Cho Cells

Chotigeat, W, Watanapokasin, Y, Mahler, S and Gray, PP (1994). Role of Environmental-Conditions On the Expression Levels, Glycoform Pattern and Levels of Sialyltransferase for Hfsh Produced by Recombinant Cho Cells. Cell Culture Engineering IV Conference, San Diego Ca, Mar 07-12, 1994. DORDRECHT: SPRINGER. doi: 10.1007/BF00762396

Comparative-Studies On Plasma-Membrane Isolated From Liver, Hepatoma and Regenerating Liver

Mahler, S, Wilce, PA and Shanley, BC (1986). Comparative-Studies On Plasma-Membrane Isolated From Liver, Hepatoma and Regenerating Liver. BALGOWLAH: ADIS PRESS AUSTRALASIA P/L.

Membrane Fluidity in Rat Hepatoma Plasma-Membranes

Mahler, S, Shanley, BC and Wilce, PA (1984). Membrane Fluidity in Rat Hepatoma Plasma-Membranes. CLAYTON: PROC AUST BIOCHEMICAL SOC.

Anti-CD83 antibodies and use thereof

Seldon, T. A., Munster, D. J., Hart, D. N., Jones, M. L., Munro, T. P., Mahler, S. M., Zhou, Y. and Marks, D. (2013). Anti-CD83 antibodies and use thereof.

Isolation method for recombinant glycoprotein biopharmaceuticals

Catzel, D., Gray, P. P. and Mahler, S. M. (2003). Isolation method for recombinant glycoprotein biopharmaceuticals. Australian Provisional Patent #61759780.

Compositions for protein delivery via the pulmonary route

Mahler, S. M., Waters, M., Chan, H. K. and Goodall, S. (2001). Compositions for protein delivery via the pulmonary route.

Process for production of glycoproteins

Mahler, S. M., Gebert, C., Chotigeat, W. and Gray, P. P. (1996). Process for production of glycoproteins.

A system for expression of recombinant proteins

Rajkovic, I., Chin, C. K. and Mahler, S. M. (1996). A system for expression of recombinant proteins. PM4219.