The University of Queensland

Determination of the alpha-conotoxin Vc1.1 binding site on the alpha 9 alpha 10 nicotinic acetylcholine receptor

Yu, Rilei, Kompella, Shiva N., Adams, David J., Craik, David J. and Kaas, Quentin (2013) Determination of the alpha-conotoxin Vc1.1 binding site on the alpha 9 alpha 10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry, 56 9: 3557-3567. doi:10.1021/jm400041h

Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor

Yu, Rilei, Kaas, Quentin and Craik, David J. (2012) Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor. The Journal of Physical Chemistry B, 116 21: 6097-6105. doi:10.1021/jp301352d

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

Kaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012) ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 D1: D325-D330. doi:10.1093/nar/gkr886

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

Yu, Rilei, Craik, David J. and Kaas, Quentin (2011) Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 3: e1002011-1-e1002011-16. doi:10.1371/journal.pcbi.1002011

Conopeptide characterization and classifications: An analysis using ConoServer

Kaas, Quentin, Westermann, Jan-Christoph and Craik, David J. (2010) Conopeptide characterization and classifications: An analysis using ConoServer. Toxicon, 55 8: 1491-1509. doi:10.1016/j.toxicon.2010.03.002

ConoServer, a database for conopeptide sequences and structures

Kaas, Quentin, Westermann, Jan, Halai, Reena, Wang, Conan and Craik, David J. (2008) ConoServer, a database for conopeptide sequences and structures. Bioinformatics, 24 3: 445-446. doi:10.1093/bioinformatics/btm596

A practical guide to structural aspects of macrocycles (NMR, x-ray, and modeling)

Craik, David J., Kaas, Quentin and Wang, Conan K. (2017). A practical guide to structural aspects of macrocycles (NMR, x-ray, and modeling). In Eric Marsault and Mark L Peterson (Ed.), Practical medicinal chemistry with macrocycles: Design, synthesis, and case studies (pp. 25-57) Hoboken, New Jersey, United States: John Wiley & Sons. doi:10.1002/9781119092599.ch2

Conotoxins and other conopeptides

Kaas, Quentin and Craik, David J. (2014). Conotoxins and other conopeptides. In Stéphane La Barre and Jean-Michel Kornprobst (Ed.), Outstanding Marine Molecules: Chemistry, Biology, Analysis (pp. 319-332) Weinheim, Germany: Wiley-VCH Verlag. doi:10.1002/9783527681501.ch14

Antimicrobial Peptides in Plants

Kaas, Quentin, Westermann, Jan-Christoph, Troeira Henriques, Sonia and Craik, David J. (2010). Antimicrobial Peptides in Plants. In Guangshun Wang (Ed.), Antimicrobial Peptides: Discovery, Design, and Novel Therapeutic Strategies (pp. 40-71) Wallingford, Oxfordshire, UK: CAB International. doi:10.1079/9781845936570.0040

IMGT standardization for molecular characterization of the T-cell receptor/peptide/MHC complexes

Kaas, Quentin, Duprat, Elodie, Tourneur, Guillaume and Lefranc, Marie-Paule (2008). IMGT standardization for molecular characterization of the T-cell receptor/peptide/MHC complexes. In Immunoinformatics (pp. 19-49) : Springer New York. doi:10.1007/978-0-387-72968-8_2

Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

Yu, Rilei, Tae, Han‐Shen, Xu, Qingliang, Craik, David J., Adams, David J., Jiang, Tao and Kaas, Quentin (2019) Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British Journal of Pharmacology, . doi:10.1111/bph.14698

Single amino acid substitution in α-conotoxin TxID reveals a specific α3β4 nicotinic acetylcholine receptor antagonist

Yu, Jinpeng, Zhu, Xiaopeng, Harvey, Peta J., Kaas, Quentin, Zhangsun, Dongting, Craik, David J. and Luo, Sulan (2018) Single amino acid substitution in α-conotoxin TxID reveals a specific α3β4 nicotinic acetylcholine receptor antagonist. Journal of Medicinal Chemistry, 61 20: 9256-9265. doi:10.1021/acs.jmedchem.8b00967

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J., Craik, David J. and Kaas, Quentin (2018) Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology, 155 288-297. doi:10.1016/j.bcp.2018.07.007

Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor

Wong, Lilian L. L., Scott, Daniel James, Hossain, Mohammed Akhter, Kaas, Quentin, Rosengren, K. Johan and Bathgate, Ross A. D. (2018) Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor. Journal of Biological Chemistry, 293 41: 15777-15789. doi:10.1074/jbc.ra118.002645

Prediction of disulfide dihedral angles using chemical shifts

Armstrong, David A., Kaas, Quentin and Rosengren, K. Johan (2018) Prediction of disulfide dihedral angles using chemical shifts. Chemical Science, 9 31: 6548-6556. doi:10.1039/c8sc01423j

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018) Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 1: 2411. doi:10.1038/s41467-018-04669-9

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1

Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018) Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 8: 3674-3684. doi:10.1021/acs.jmedchem.8b00170

Bioactive compounds isolated from neglected predatory marine gastropods

Turner, Ashlin H., Craik, David J., Kaas, Quentin and Schroeder, Christina I. (2018) Bioactive compounds isolated from neglected predatory marine gastropods. Marine Drugs, 16 4: 118. doi:10.3390/md16040118

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

Castro, Joel, Grundy, Luke, Deiteren, Annemie, Harrington, Andrea M., O'Donnell, Tracey, Maddern, Jessica, Moore, Jessi, Garcia-Caraballo, Sonia, Rychkov, Grigori Y., Yu, Rilei, Kaas, Quentin, Craik, David J., Adams, David J. and Brierley, Stuart M. (2018) Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology, 175 12: 2384-2398. doi:10.1111/bph.14115

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin

Wang, Conan K., Swedberg, Joakim E., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2018) Conformational Flexibility Is a Determinant of Permeability for Cyclosporin. The Journal of Physical Chemistry. B, 122 8: 2261-2276. doi:10.1021/acs.jpcb.7b12419

Computational Studies of Snake Venom Toxins

Ojeda, Paola G., Ramírez, David, Alzate-Morales, Jans, Caballero, Julio, Kaas, Quentin and González, Wendy (2017) Computational Studies of Snake Venom Toxins. Toxins, 10 1: 1-24. doi:10.3390/toxins10010008

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

Pineda, Sandy S., Chaumeil, Pierre-Alain, Kunert, Anne, Kaas, Quentin, Thang, Mike W. C., Le, Lien, Nuhn, Michael, Herzig, Volker, Saez, Natalie J., Cristofori-Armstrong, Ben, Anangi, Raveendra, Senff, Sebastian, Gorse, Dominique and King, Glenn F. (2017) ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins. Bioinformatics, 34 6: 1074-1076. doi:10.1093/bioinformatics/btx661

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017) Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 41: 17101-17112. doi:10.1074/jbc.M117.808386

Modelling the interactions between animal venom peptides and membrane proteins

Hung, Andrew, Kuyucak, Serdar, Schroeder, Christina I. and Kaas, Quentin (2017) Modelling the interactions between animal venom peptides and membrane proteins. Neuropharmacology, 127 20-31. doi:10.1016/j.neuropharm.2017.07.036

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors

Li, Ming-Jing, Wu, Guan-Zhao, Kaas, Quentin, Jiang, Tao and Yu, Ri-Lei (2017) Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors. Journal of Molecular Graphics and Modelling, 75 241-249. doi:10.1016/j.jmgm.2017.04.004

Role of CysI–CysIII disulfide bond on the structure and activity of α-conotoxins at human neuronal nicotinic acetylcholine receptors

Tabassum, Nargis, Tae, Han-Shen, Jia, Xinying, Kaas, Quentin, Jiang, Tao, Adams, David J. and Yu, Rilei (2017) Role of CysI–CysIII disulfide bond on the structure and activity of α-conotoxins at human neuronal nicotinic acetylcholine receptors. ACS Omega, 2 8: 4621-4631. doi:10.1021/acsomega.7b00639

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

Wu, Yong, Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Zhangsun, Manqi, Harvey, Peta J., Craik, David J., McIntosh, J. Michael and Luo, Sulan (2017) α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry, 60 13: 5826-5833. doi:10.1021/acs.jmedchem.7b00546

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype

Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Wu, Yong, Craik, David J. , McIntosh, J. Michael and Luo, Sulan (2017) αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype. Neuropharmacology, 127 243-252. doi:10.1016/j.neuropharm.2017.04.015

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016) Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 10: 2202-2212. doi:10.1002/bit.25993

Accurate de novo design of hyperstable constrained peptides

Bhardwaj, Gaurav, Mulligan, Vikram Khipple, Bahl, Christopher D., Gilmore, Jason M., Harvey, Peta J., Cheneval, Olivier, Buchko, Garry W., Pulavarti, Surya V. S. R. K., Kaas, Quentin, Eletsky, Alexander, Huang, Po-Ssu, Johnsen, William A., Greisen, Per Jr, Rocklin, Gabriel J., Song, Yifan, Linsky, Thomas W., Watkins, Andrew, Rettie, Stephen A., Xu, Xianzhong, Carter, Lauren P., Bonneau, Richard, Olson, James M., Coutsias, Evangelos, Correnti, Colin E., Szyperski, Thomas, Craik, David J. and Baker, David (2016) Accurate de novo design of hyperstable constrained peptides. Nature, 538 7625: 329-335. doi:10.1038/nature19791

Cyclisation of disulfide-rich conotoxins in drug design applications

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016) Cyclisation of disulfide-rich conotoxins in drug design applications. European Journal of Organic Chemistry, 2016 21: 3462-3472. doi:10.1002/ejoc.201600402

Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016)

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016) Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016). European Journal of Organic Chemistry, 2016 21: 3457-3457. doi:10.1002/ejoc.201670211

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

Harris, Karen S., Durek, Thomas, Kaas, Quentin, Poth, Aaron G., Gilding, Edward K., Conlan, Brendon F., Saska, Ivana, Daly, Norelle L., Van Der Weerden, Nicole L., Craik, David J. and Anderson, Marilyn A. (2015) Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase. Nature Communications, 6 10199: . doi:10.1038/ncomms10199

Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae

Ravipati, Anjaneya S., Henriques, Sónia Troeira, Poth, Aaron G., Kaas, Quentin, Wang, Conan K., Colgrave, Michelle L. and Craik, David J. (2015) Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae. ACS Chemical Biology, 10 11: 2491-2500. doi:10.1021/acschembio.5b00454

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1

Yu, Rilei, Seymour, Victoria A. L., Berecki, Geza, Jia, Xinying, Akcan, Muharrem, Adams, David J., Kaas, Quentin and Craik, David J. (2015) Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Scientific Reports, 5 Art No.: 13264: . doi:10.1038/srep13264

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Huang, Yen-Hua, Henriques, Sonia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin and Craik, David J. (2015) Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5 1-15. doi:10.1038/srep12974

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist

Luo, Sulan, Zhangsun, Dongting, Harvey, Peta J., Kaas, Quentin, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Li, Xiaodan, Tsetlin, Victor. I., Christensen, Sean, Romero, Haylie K., McIntrye, Melissa, Dowell, Cheryl, Baxter, James, C., Elmslie, Keith S., Craik, David J. and McIntosh, Michael (2015) Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 30: e4026-e4035. doi:10.1073/pnas.1503617112

Bioinformatics-aided venomics

Kaas, Quentin and Craik, David J. (2015) Bioinformatics-aided venomics. Toxins, 7 6: 2159-2187. doi:10.3390/toxins7062159

Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding

Zhangsun, Dongting, Zhu, Xiaopeng, Wu, Yong, Hu, Yuanyan, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Luo, Sulan (2015) Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding. The Journal of Biological Chemistry, 290 15: 9855-9862. doi:10.1074/jbc.M114.632646

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

Babbitt, Patricia C, Bagos, Pantelis G, Bairoch, Amos, Bateman, Alex, Chatonnet, Arnaud, Chen, Mark Jinan, Craik, David J, Finn, Robert D, Gloriam, David, Haft, Daniel H, Henrissat, Bernard, Holliday, Gemma L, Isberg, Vignir, Kaas, Quentin, Landsman, David, Lenfant, Nicolas, Manning, Gerard, Nagano, Nozomi, Srinivasan, Narayanaswamy, O'Donovan, Claire, Pruitt, Kim D, Sowdhamini, Ramanathan, Rawlings, Neil D, Saier Jr., Milton H, Sharman, Joanna L, Spedding, Michael, Tsirigos, Konstantinos D, Vastermark, Ake and Vriend, Gerrit (2015) Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database The Journal of Biological Databases and Curation, 2015 bav063: . doi:10.1093/database/bav063

The evolution of Momordica cyclic peptides

Mahatmanto, Tunjung, Mylne, Joshua S., Poth, Aaron G., Swedberg, Joakim E., Kaas, Quentin, Schaefer, Hanno and Craik, David J. (2014) The evolution of Momordica cyclic peptides. Molecular Biology and Evolution, 32 2: 392-405. doi:10.1093/molbev/msu307

Characterisation of the subunit genes of pyrophosphate-dependent phosphofructokinase from loquat (Eriobotrya japonica Lindl.)

Qin, Qiaoping, Kaas, Quentin, Wu, Wenming, Lin, Feifan, Lai, Qixian and Zhu, Zhujun (2014) Characterisation of the subunit genes of pyrophosphate-dependent phosphofructokinase from loquat (Eriobotrya japonica Lindl.). Tree Genetics & Genomes, 10 5: 1465-1476. doi:10.1007/s11295-014-0774-5

Discovery, synthesis, and structure: activity relationships of conotoxins

Akondi, Kalyana, Muttenthaler, Markus, Dutertre, Sébastien, Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2014) Discovery, synthesis, and structure: activity relationships of conotoxins. Chemical Reviews, Articles ASAP 11: 1-33. doi:10.1021/cr400401e

A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors

Luo, Sulan, Zhangsun, Dongting, Schroeder, Christina I., Zhu, Xiaopeng, Hu, Yuanyan, Wu, Yong, Weltzin, Maegan M., Eberhard, Spencer, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Whiteaker, Paul (2014) A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3 beta2 vs. alpha6/alpha3 beta2 beta3 nicotinic acetylcholine receptors. FASEB Journal, Early Edition 4: 1-12. doi:10.1096/fj.13-244103

Prediction and characterization of cyclic proteins from sequences in three domains of life

Kedarisetti, Pradyumna, Mizianty, Marcin J., Kaas, Quentin, Craik, David J. and Kurgan, Lukasz (2014) Prediction and characterization of cyclic proteins from sequences in three domains of life. Biochimica et Biophysica Acta: Proteins and Proteomics, 1844 1: 181-190. doi:10.1016/j.bbapap.2013.05.002

Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity

Jin, Ai-Hua, Dutertre, Sébastien, Kaas, Quentin, Lavergne, Vincent, Kubala, Petra, Lewis, Richard J. and Alewood, Paul F. (2013) Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Molecular and Cellular Proteomics, 12 12: 3824-3833. doi:10.1074/mcp.M113.030353

A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic and peptidomic analysis

Gerlach, Samantha L., Göransson, Ulf, Kaas, Quentin, Craik, David J. and Gruber, Christian W. (2013) A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic and peptidomic analysis. Biopolymers: Peptide Science, 100 5: 433-437. doi:10.1002/bip.22258

Determination of the alpha-conotoxin Vc1.1 binding site on the alpha 9 alpha 10 nicotinic acetylcholine receptor

Yu, Rilei, Kompella, Shiva N., Adams, David J., Craik, David J. and Kaas, Quentin (2013) Determination of the alpha-conotoxin Vc1.1 binding site on the alpha 9 alpha 10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry, 56 9: 3557-3567. doi:10.1021/jm400041h

High-affinity cyclic peptide matriptase inhibitors

Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A. and Daly, Norelle L. (2013) High-affinity cyclic peptide matriptase inhibitors. Journal of Biological Chemistry, 288 19: 13885-13896. doi:10.1074/jbc.M113.460030

NMR of plant proteins

Kaas, Quentin and Craik, David J. (2013) NMR of plant proteins. Progress in Nuclear Magnetic Resonance Spectroscopy, 71 1-34. doi:10.1016/j.pnmrs.2013.01.003

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily

Aguilar, Manuel B., Ortiz, Ernesto, Kaas, Quentin, Lopez-Vera, Estuardo, Becerril, Baltazar, Possani, Lourival D. and Heimer de la Cotera, Edgar P. (2013) Precursor De13.1 from Conus delessertii defines the novel G gene superfamily. Peptides, 41 17-20. doi:10.1016/j.peptides.2013.01.009

Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom

Dutertre, Sebastien, Jin, Ai-Hua (Jean), Kaas, Quentin, Jones, Alun, Alewood, Paul F. and Lewis, Richard J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Molecular and Cellular Proteomics, 12 2: 312-329. doi:10.1074/mcp.M112.021469

Isolation and characterization of a cytosolic pyruvate kinase cDNA from loquat (Eriobotrya japonica Lindl.)

Qin, Qiaoping, Kaas, Quentin, Zhang, Lanlan, Xu, Kai, Li, Nanyi, Zheng, Weiwei and Lai, Qixian (2013) Isolation and characterization of a cytosolic pyruvate kinase cDNA from loquat (Eriobotrya japonica Lindl.). Plant Molecular Biology Reporter, 31 1: 109-119. doi:10.1007/s11105-012-0479-6

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Bathgate, Ross A. D., Oh, Maria H. Y., Ling, W. J. Jason, Kaas, Quentin, Hossain, M. Akhter, Gooley, Paul R. and Rosengren, K. Johan (2013) Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3. Frontiers in Endocrinology, 4 FEB: . doi:10.3389/fendo.2013.00013

The Cold Awakening of Doritaenopsis 'Tinny Tender' Orchid Flowers: The Role of Leaves in Cold-induced Bud Dormancy Release

Qin, Qiaoping, Kaas, Quentin, Zhang, Chi, Zhou, Luping, Luo, Xiaoyan, Zhou, Mingbing, Sun, Xiaoming, Zhang, Lanlan, Paek, Kee-Yoeup and Cui, Yongyi (2012) The Cold Awakening of Doritaenopsis 'Tinny Tender' Orchid Flowers: The Role of Leaves in Cold-induced Bud Dormancy Release. Journal of Plant Growth Regulation, 31 2: 139-155. doi:10.1007/s00344-011-9226-8

Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor

Yu, Rilei, Kaas, Quentin and Craik, David J. (2012) Delineation of the unbinding pathway of alpha-conotoxin Iml from the a7 nicotinic acetylcholine receptor. The Journal of Physical Chemistry B, 116 21: 6097-6105. doi:10.1021/jp301352d

Cyclization of conotoxins to improve their biopharmaceutical properties

Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012) Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 4: 446-455. doi:10.1016/j.toxicon.2010.12.003

Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012) Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 8: . doi:10.2174/138161212799315858

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

Kaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012) ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 D1: D325-D330. doi:10.1093/nar/gkr886

Engineering of conotoxins for the treatment of pain

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011) Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 38: 4242-4253.

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

Yu, Rilei, Craik, David J. and Kaas, Quentin (2011) Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 3: e1002011-1-e1002011-16. doi:10.1371/journal.pcbi.1002011

ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

Volker, Herzig, Wood, David, Newell, Felicity, Chaumeil, Pierre-Alain, Kaas, Quentin, Binford, Greta J., Nicholson, Graham M., Gorse, Dominique and King, Glenn F. (2011) ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures. Nucleic Acids Research, 39 Supp. 1: D653-D657. doi:10.1093/nar/gkq1058

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

Dunse, K. M., Kaas, Q., Guarino, R. F., Barton, P. A., Craik, D. J. and Anderson, M. A. (2010) Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America., 107 34: 15016-15021. doi:10.1073/pnas.1009327107

Conopeptide characterization and classifications: An analysis using ConoServer

Kaas, Quentin, Westermann, Jan-Christoph and Craik, David J. (2010) Conopeptide characterization and classifications: An analysis using ConoServer. Toxicon, 55 8: 1491-1509. doi:10.1016/j.toxicon.2010.03.002

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

Qin, Qiaoping, McCallum, Emily J., Kaas, Quentin, Suda, Jan, Saska, Ivana, Craik, David J. and Mylne, Joshua S. (2010) Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis. BMC Genomics, 11 111: 1-11. doi:10.1186/1471-2164-11-111

Analysis and classification of circular proteins in CyBase

Kaas, Quentin and Craik, David J (2010) Analysis and classification of circular proteins in CyBase. Biopolymers, 94 5: 584-591. doi:10.1002/bip.21424

IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T-cell receptors, MHC, IgSF and MhcSF

Ehrenmann, F., Kaas, Q. and Lefranc, M.-P. (2009) IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T-cell receptors, MHC, IgSF and MhcSF. Nucleic Acids Research, 33 Supp. 1: D301-D307. doi:10.1093/nar/gkp946

Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes

Wang, C. K., Colgrave, M. L., Ireland, D. C., Kaas, Q and Craik, D. J. (2009) Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophysical Journal, 97 5: 1471-1481. doi:10.1016/j.bpj.2009.06.032

ArachnoServer: a database of protein toxins from spiders

Wood, D. L. A., Miljenovic, T, Cai, S, Raven, R. J., Kaas, Q, Escoubas, P, Herzig, V, Wilson, D and King, G (2009) ArachnoServer: a database of protein toxins from spiders. BMC Genomics, 10 Article #375: 1-8. doi:10.1186/1471-2164-10-375

CyBase: a database of cyclic protein sequences and structures, with application in protein discovery and engineering

Wang, C. K., Kaas, Q., Chiche, L. and Craik, D. J. (2008) CyBase: a database of cyclic protein sequences and structures, with application in protein discovery and engineering. Nucleic Acids Research, 36 SUPPL. 1: D206-D210. doi:10.1093/nar/gkm953

IMGT-Kaleidoscope, the formal IMGT-ONTOLOGY paradigm

Duroux, Patrice, Kaas, Quentin, Brochet, Xavier, Lane, Jérôme, Ginestoux, Chantal, Lefranc, Marie-Paule and Giudicelli, Véronique (2008) IMGT-Kaleidoscope, the formal IMGT-ONTOLOGY paradigm. Biochimie, 90 4: 570-583. doi:10.1016/j.biochi.2007.09.003

ConoServer, a database for conopeptide sequences and structures

Kaas, Quentin, Westermann, Jan, Halai, Reena, Wang, Conan and Craik, David J. (2008) ConoServer, a database for conopeptide sequences and structures. Bioinformatics, 24 3: 445-446. doi:10.1093/bioinformatics/btm596

KNOTTIN: The knottin or inhibitor cystine knot scaffold in 2007

Gracy, Jérôme, Le Nguyen, Dung, Gelly, Jean Christophe, Kaas, Quentin, Heitz, Annie and Chiche, Laurent (2008) KNOTTIN: The knottin or inhibitor cystine knot scaffold in 2007. Nucleic Acids Research, 36 SUPPL. 1: D314-D319. doi:10.1093/nar/gkm939

IG, TR and IgSF, MHC and MhcSF: what do we learn from the IMGT Colliers de Perles?

Kaas, Quentin, Ehrenmann, Francois and Lefranc, Marie-Paule (2007) IG, TR and IgSF, MHC and MhcSF: what do we learn from the IMGT Colliers de Perles?. Briefings in Functional Genomics and Proteomics, 6 4: 253-264. doi:10.1093/bfgp/elm032

Structure–function relationships of the variable domains of monoclonal antibodies approved for cancer treatment

Magdelaine-Beuzelin, Charlotte, Kaas, Quentin, Wehbi, Vanessa, Ohresser, Marc, Jefferis, Roy, Lefranc, Marie-Paule and Watier. Hervé (2007) Structure–function relationships of the variable domains of monoclonal antibodies approved for cancer treatment. Critical reviews in Oncology/Hematology, 64 3: 210-225. doi:10.1016/j.critrevonc.2007.04.011

IMGT colliers de perles: Standardized sequence-structure representations of the IgSF and MhcSF superfamily domains

Kaas, Quentin and Leffranc, Marie-Paule (2007) IMGT colliers de perles: Standardized sequence-structure representations of the IgSF and MhcSF superfamily domains. Current Bioinformatics, 2 1: 21-30. doi:10.2174/157489307779314302

T cell receptor/peptide/MHC molecular characterization and standardized pMHC contact sites in IMGT/3Dstructure-DB

Kaas, Quentin and Lefranc , Marie-Paule (2005) T cell receptor/peptide/MHC molecular characterization and standardized pMHC contact sites in IMGT/3Dstructure-DB. In Silico Biology, 5 5-6: 505-528.

IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN

Lefranc, Marie-Paule, Duprat, Elodie, Kaas, Quentin, Tranne, Madeleine, Thiriot , Aude and Lefranc, Gérard (2005) IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN. Developmental and comparative immunology, 29 11: 917-938. doi:10.1016/j.dci.2005.03.003

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

Lefranc, Marie-Paule, Pommié, Christelle, Kaas, Quentin, Duprat, Elodie, Bosc, Nathalie, Guiraudou, Delphine, Jean, Christelle, Ruiz, Manuel, Da Piédade, Isabelle, Rouard, Mathieu, Foulquier, Elodie, Thouvenin, Valerie and Lefranc, Gerard (2005) IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains. Developmental and Comparative Immunology, 29 3: 185-203. doi:10.1016/j.dci.2004.07.003

IMGT, the international ImMunoGeneTics information system

Lefranc, Marie-Paule, Giudicelli, Veronique, Kaas, Quentin, Clément, Oliver, Duprat, Elodie, Jabado-Michaloud, Joumana, Scaviner, Dominqiue, Ginestoux, Chantal, Chaume, Denys and Lefranc, Gerard (2005) IMGT, the international ImMunoGeneTics information system. Nucleic Acids Research, 33 Database Issue Supplement 1: D593-D597. doi:10.1093/nar/gki065

IMGT-choreography for immunogenetics and immunoinformatics

Lefranc, Marie-Paule, Clement, Oliver, Kaas, Quentin, Duprat, Elodie, Chastellan, Patrick, Coelho, Isabelle, Combres, Kora, Ginestoux, Chantal, Giudicelli, Veronique, Chaume, Denys and Lefranc, Gerard (2005) IMGT-choreography for immunogenetics and immunoinformatics. In Silico Biology, 5 1: 45-60.

High-Resolution X-ray Structure of the Unexpectedly Stable Dimer of the [Lys(-2)-Arg(-1)-des(17−21)]Endothelin-1 Peptide

Hoh, Francois, Cerdan, Rachel, Kaas, Quentin, Nishi, Yoshinri, Chiche, Laurent, Kubo, Shigeru, Chino, Naoyoshi and Kobayashi, Yjui (2004) High-Resolution X-ray Structure of the Unexpectedly Stable Dimer of the [Lys(-2)-Arg(-1)-des(17−21)]Endothelin-1 Peptide. Biochemistry, 43 48: 15154-15168. doi:10.1021/bi049098a

IMGT-ONTOLOGY for Immunogenetics and Immunoinformatics

Lefranc, Marie-Paule, Giudicelli, Véronique, Ginestoux, Chantal, Bosc, Nathalie, Folch, Géraldine, Guiraudou, Delphine, Jabado-Michaloud, Joumana, Magris, Séverine, Scaviner, Dominique, Thouvenin, Valérie, Combres, Kora, Girod, David, Jeanjean, Stéphanie, Protat, Céline, Monod, Mehdi Yousfi, Duprat, Elodie, Kaas, Quentin, Pommié, Christelle, Chaume, Denys and Lefranc, Gérard (2004) IMGT-ONTOLOGY for Immunogenetics and Immunoinformatics. In Silico Biology, 4 1: 17-29.

IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data

Kaas, Q., Ruiz, M. and LeFranc, M-P (2004) IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data. Nucleic Acids Research, 32 Database Issue: D208-D210. doi:10.1093/nar/gkh042

The KNOTTIN website and database: a new information system dedicated to the knottin scaffold

Gelly, Jean-Christophe, Gracy, Jérôme, Kaas, Quentin, Le-Nguyen, Dung, Heitz, Annie and Chiche, Laurent (2004) The KNOTTIN website and database: a new information system dedicated to the knottin scaffold. Nucleic acids research, 32(Database edition) D156-D159. doi:10.1093/nar/gkh015

The [Lys-2-Arg-1-des(17−21)]-Endothelin-1 Peptide Retains the Specific Arg-1−Asp8 Salt Bridge but Reveals Discrepancies between NMR Data and Molecular Dynamics Simulations

Kaas, Quentin, Aumelas, André, Kubo, Shigeru, Chino, Naoyoshi, Kobayashi, Yuji and Chiche, Laurent (2002) The [Lys-2-Arg-1-des(17−21)]-Endothelin-1 Peptide Retains the Specific Arg-1−Asp8 Salt Bridge but Reveals Discrepancies between NMR Data and Molecular Dynamics Simulations. Biochemistry, 47 37: 11099-11198. doi:10.1021/bi025744z

SCORE: Predicting the core of protein models

Deane, Charlotte M., Kaas, Quentin and Blundell, Tom L. (2001) SCORE: Predicting the core of protein models. Bioinformatics, 17 6: 541-550. doi:10.1093/bioinformatics/17.6.541

SCORE: predicting the core of protein models

Deane, C M, Kaas, Q and Blundell, T L (2001) SCORE: predicting the core of protein models. Bioinformatics (Oxford, England), 17 6: 541-50.

Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins

Kaas, Quentin, Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J. and Craik, David (2018). Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins. In: 35th European Peptide Symposium, Dublin City University, Ireland, (S62-S62). 26-31 August 2018.

Targeting the coiled-coil domain of BCR-ABL1 kinase with new weapons

Huang, Yen-Hua, Passioura, Toby, Peacock, Hayden, Henriques, Sonia Troeira, Wang, Conan, Kaas, Quentin, Suga, Hiroaki and Craik, David (2018). Targeting the coiled-coil domain of BCR-ABL1 kinase with new weapons. In: 35th European Peptide Symposium, Dublin City University, Ireland, (S160-S160). 26-31 August 2018.

Inhibitory Effects of Substrate-Based Bcr-Abl1 Kinase Inhibitors On the Growth of Chronic Myeloid Leukemia Cell Line K562

Huang, Y. -H., Henriques, S. Troeira, Lawrence, N., Kaas, Q. and Craik, D. J. (2016). Inhibitory Effects of Substrate-Based Bcr-Abl1 Kinase Inhibitors On the Growth of Chronic Myeloid Leukemia Cell Line K562. In: 34th European Peptide Symposium, Leipzig, Germany, (S174-S174). 4‐9 September 2016. doi:10.1002/psc.2950

Towards An Understanding of A- Conotoxin Receptor Specificity

Kaas, Q. and Craik, D. J. (2016). Towards An Understanding of A- Conotoxin Receptor Specificity. In: , , (S128-S128). .

Transcriptomic and peptidomic characterisation of the Conus marmoreus venom: Insights on conopeptide diversity and venomic processing

Jin, Ai-hua, Dutertre, Sébastien, Kaas, Quentin, Lewis, Richard J. and Alewood, Paul F. (2012). Transcriptomic and peptidomic characterisation of the Conus marmoreus venom: Insights on conopeptide diversity and venomic processing. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (144-145). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.099

A new "Era" for cyclotide sequencing

Colgrave, Michelle L., Poth, Aaron G., Kaas, Quentin and Craik, David J. (2010). A new "Era" for cyclotide sequencing. In: 1st International Conference on Circular Proteins. Procceedings.. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, (592-601). 18-21 October 2009. doi:10.1002/bip.21400

Advances in MS/MS Sequencing of Cyclic Peptides: What's around the Bend?

Colgrave, L., Poth, A., Kaas, Q. and Craik, D. (2010). Advances in MS/MS Sequencing of Cyclic Peptides: What's around the Bend?. In: Journal of Peptide Science. x, x, (113-113). x. doi:10.1002/psc.1303

Analysis and classification of circular proteins in CyBase

Kaas, Quentin and Craik, David J. (2010). Analysis and classification of circular proteins in CyBase. In: International Conference on Circular Proteins. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, (584-591). 18-21 October, 2009. doi:10.1002/bip.21424