The University of Queensland

Synthesis and characterization of nanomaterials using microfluidic technology

Zhao, Chun-Xia and Middelberg, Anton P. J. (2016). Synthesis and characterization of nanomaterials using microfluidic technology. In Mahmood Aliofkhazraei (Ed.), Handbook of nanoparticles (pp. 455-473) Cham, Switzerland: Springer International Publishing. doi:10.1007/978-3-319-15338-4_23

Stimuli-responsive peptide nanostructures at the fluid-fluid interface

Zhao, Chun-Xia and Middelberg, Anton P.J. (2013). Stimuli-responsive peptide nanostructures at the fluid-fluid interface. In Juliet A. Gerrard (Ed.), Protein nanotechnology: protocols, instrumentation, and applications 2nd ed. (pp. 179-194) New York, NY United States: Humana Press. doi:10.1007/978-1-62703-354-1_10

Tumor-Vasculature-on-a-Chip for Investigating Nanoparticle Extravasation and Tumor Accumulation

Wang, Hao-Fei, Ran, Rui, Liu, Yun, Hui, Yue, Zeng, Bijun, Chen, Dong, Weitz, David A. and Zhao, Chun-Xia (2018) Tumor-Vasculature-on-a-Chip for Investigating Nanoparticle Extravasation and Tumor Accumulation. ACS Nano, . doi:10.1021/acsnano.8b06846

Microfluidic Formation of Coculture Tumor Spheroids with Stromal Cells As a Novel 3D Tumor Model for Drug Testing

Sun, Qi, Tan, Say Hwa, Chen, Qiushui, Ran, Rui, Hui, Yue, Chen, Dong and Zhao, Chun-Xia (2018) Microfluidic Formation of Coculture Tumor Spheroids with Stromal Cells As a Novel 3D Tumor Model for Drug Testing. ACS Biomaterials Science & Engineering, . doi:10.1021/acsbiomaterials.8b00904

Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting

Ran, Rui, Wang, Haofei, Liu, Yun, Hui, Yue, Sun, Qi, Seth, Arjun, Wibowo, David, Chen, Dong and Zhao, Chun-Xia (2018) Microfluidic self-assembly of a combinatorial library of single- and dual-ligand liposomes for in vitro and in vivo tumor targeting. European Journal of Pharmaceutics and Biopharmaceutics, 130 1-10. doi:10.1016/j.ejpb.2018.06.017

Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting

Liu, Yun, Hui, Yue, Ran, Rui, Yang, Guang-Ze, Wibowo, David, Wang, Hao-Fei, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018) Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting. Advanced Healthcare Materials, 7 15: 1800106. doi:10.1002/adhm.201800106

Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting

Hui, Yue, Wibowo, David, Liu, Yun, Ran, Rui, Wang, Hao-Fei, Seth, Arjun, Middelberg, Anton P J and Zhao, Chun-Xia (2018) Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting. ACS Nano, 12 3: 2846-2857. doi:10.1021/acsnano.8b00242

Cost-effective downstream processing of recombinantly produced pexiganan peptide and its antimicrobial activity

Sun, Baode, Wibowo, David, Middelberg, Anton P. J. and Zhao, Chun-Xia (2018) Cost-effective downstream processing of recombinantly produced pexiganan peptide and its antimicrobial activity. AMB Express, 8 1: 6. doi:10.1186/s13568-018-0541-3

Design and production of a novel antimicrobial fusion protein in Escherichia coli

Sun, Baode, Wibowo, David, Sainsbury, Frank and Zhao, Chun-Xia (2018) Design and production of a novel antimicrobial fusion protein in Escherichia coli. Applied Microbiology and Biotechnology, 102 20: 8763-8772. doi:10.1007/s00253-018-9319-4

Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides

Wibowo, David and Zhao, Chun-Xia (2018) Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides. Applied Microbiology and Biotechnology, . doi:10.1007/s00253-018-9524-1

Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants

Chen, Dong, Amstad, Esther, Zhao, Chun-Xia, Cai, Liheng, Fan, Jing, Chen, Qiushui, Hai, Mingtan, Koehler, Stephan, Zhang, Huidan, Liang, Fuxin, Yang, Zhenzhong and Weitz, David A (2017) Biocompatible amphiphilic hydrogel-solid dimer particles as colloidal surfactants. ACS Nano, 11 12: 11978-11985. doi:10.1021/acsnano.7b03110

Dispersing hydrophobic natural colourant β-carotene in shellac particles for enhanced stability and tunable colour

Chen, Dong, Zhao, Chun-Xia, Lagoin, Camille, Hai, Mingtan, Arriaga, Laura R., Koehler, Stephan, Abbaspourrad, Alireza and Weitz, David A. (2017) Dispersing hydrophobic natural colourant β-carotene in shellac particles for enhanced stability and tunable colour. Royal Society Open Science, 4 12: 170919. doi:10.1098/rsos.170919

Multiphase microfluidic synthesis of micro- and nanostructures for pharmaceutical applications

Ran, Rui, Sun, Qi, Baby, Thejus, Wibowo, David, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017) Multiphase microfluidic synthesis of micro- and nanostructures for pharmaceutical applications. Chemical Engineering Science, 169 78-96. doi:10.1016/j.ces.2017.01.008

Fundamental studies on throughput capacities of hydrodynamic flow-focusing microfluidics for producing monodisperse polymer nanoparticles

Baby, Thejus, Liu, Yun, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017) Fundamental studies on throughput capacities of hydrodynamic flow-focusing microfluidics for producing monodisperse polymer nanoparticles. Chemical Engineering Science, 169 128-139. doi:10.1016/j.ces.2017.04.046

Design of modular peptide surfactants and their surface activity

Wang, Hao-Fei, Wibowo, David, Shao, Zhengzhong, Middelberg, Anton P. J. and Chun-Xia Zhao (2017) Design of modular peptide surfactants and their surface activity. Langmuir, 33 32: 7957-7967. doi:10.1021/acs.langmuir.7b01382

Biocompatible microcapsules with a water core templated from single emulsions

Kong, Linlin, Amstad, Esther, Hai, Mingtan, Ke, Xinyou, Chen, Dong, Zhao, Chun-Xia and Weitz, David A. (2017) Biocompatible microcapsules with a water core templated from single emulsions. Chinese Chemical Letters, 28 9: 1897-1900. doi:10.1016/j.cclet.2017.07.017

Conformation and self-assembly changes of isomeric peptide amphiphiles influenced by switching tyrosine in the sequences

Zhao, Fangyi, Guo, Hui, Zhang, Zhidong, Ye, John, Liu, Longlong, Zhao, Chun-Xia and Shao, Zhengzhong (2017) Conformation and self-assembly changes of isomeric peptide amphiphiles influenced by switching tyrosine in the sequences. Journal of Materials Chemistry B, 5 26: 5189-5195. doi:10.1039/c7tb00736a

Interfacial films formed by a biosurfactant modularized with a silken tail

Wibowo, David, Wang, Hao-Fei, Shao, Zhengzhong, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017) Interfacial films formed by a biosurfactant modularized with a silken tail. The Journal of Physical Chemistry C, 121 27: 14658-14667. doi:10.1021/acs.jpcc.7b03807

Biomimetic silica nanocapsules for tunable sustained release and cargo protection

Yang, Guang-Ze, Wibowo, David, Yun, Jung-Ho, Wang, Lianzhou, Middelberg, Anton P. J. and Zhao, Chun-Xia (2017) Biomimetic silica nanocapsules for tunable sustained release and cargo protection. Langmuir, 33 23: 5777-5785. doi:10.1021/acs.langmuir.7b00590

Controlled generation of ultrathin-shell double emulsions and studies on their stability

Zhao, Chun-Xia, Chen, Dong, Hui, Yue, Weitz, David A. and Middelberg, Anton P. J. (2017) Controlled generation of ultrathin-shell double emulsions and studies on their stability. ChemPhysChem, 18 10: 1393-1399. doi:10.1002/cphc.201601334

Collective generation of milliemulsions by step-emulsification

Huang, Xing, Eggersdorfer, Max, Wu, Jinrong, Zhao, Chun-Xia, Xu, Zhongbin, Chen, Dong and Weitz, David A. (2017) Collective generation of milliemulsions by step-emulsification. RSC Advances, 7 24: 14932-14938. doi:10.1039/c7ra00935f

Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules

Wibowo, David, Yang, Guang-Ze, Middelberg, Anton P.J. and Zhao, Chun-Xia (2017) Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules. Biotechnology and Bioengineering, 114 2: 335-343. doi:10.1002/bit.26079

From folding to function: design of a new switchable biosurfactant protein

Zhao, Chun-Xia, Dwyer, Mirjana, Yu, Lei and Middelberg, Anton P. J. (2017) From folding to function: design of a new switchable biosurfactant protein. ChemPhysChem, 18 5: 488-492. doi:10.1002/cphc.201601277

A partially purified outer membrane protein VirB9-1 for low-cost nanovaccines against Anaplasma marginale

Zhao, Liang, Cavallaro, Antonino S., Wibowo, David, Zhang, Bing, Zhang, Jun, Mitter, Neena, Yu, Chengzhong, Zhao, Chun-Xia and Middelberg, Anton P. J. (2017) A partially purified outer membrane protein VirB9-1 for low-cost nanovaccines against Anaplasma marginale. Vaccine, 35 1: 77-83. doi:10.1016/j.vaccine.2016.11.037

Microfluidic synthesis of multifunctional liposomes for tumour targeting

Ran, Rui, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016) Microfluidic synthesis of multifunctional liposomes for tumour targeting. Colloids and Surfaces B: Biointerfaces, 148 402-410. doi:10.1016/j.colsurfb.2016.09.016

Interfacial engineering for silica nanocapsules

Wibowo, David, Hui, Yue, Middelberg, Anton P. J. and Zhao, Chun-Xia (2016) Interfacial engineering for silica nanocapsules. Advances in Colloid and Interface Science, 236 83-100. doi:10.1016/j.cis.2016.08.001

Stable ultrathin-shell double emulsions for controlled release

Zhao, Chun-Xia, Chen, Dong, Hui, Yue, Weitz, David A. and Middelberg, Anton P. J. (2016) Stable ultrathin-shell double emulsions for controlled release. ChemPhysChem, 17 11: 1553-1556. doi:10.1002/cphc.201600142

Immunogenicity of Outer Membrane Proteins VirB9-1 and VirB9-2, a Novel Nanovaccine against Anaplasma marginale

Zhao, Liang, Mahony, Donna, Cavallaro, Antonino S., Zhang, Bing, Zhang, Jun, Deringer, James R., Brown, Wendy C., Zhao, Chun-Xia, Yu, Chengzhong, Mitter, Neena and Middelberg, Anton P. J. (2016) Immunogenicity of Outer Membrane Proteins VirB9-1 and VirB9-2, a Novel Nanovaccine against Anaplasma marginale. PLoS One, 11 4: e0154295. doi:10.1371/journal.pone.0154295

Insights into the role of biomineralizing peptide surfactants on making nanoemulsion-templated silica nanocapsules

Hui, Yue, Wibowo, David and Zhao, Chun-Xia (2016) Insights into the role of biomineralizing peptide surfactants on making nanoemulsion-templated silica nanocapsules. Langmuir, 32 3: 822-830. doi:10.1021/acs.langmuir.5b03811

Interfacial biomimetic synthesis of silica nanocapsules using a recombinant catalytic modular protein

Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2015) Interfacial biomimetic synthesis of silica nanocapsules using a recombinant catalytic modular protein. Langmuir, 31 6: 1999-2007. doi:10.1021/la504684g

A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli

Zhao, Chun-Xia, Dimitrijev Dwyer, Mirjana, Yu, Alice Lei, Wu, Yang, Fang, Sheng and Middelberg, Anton P. J. (2015) A simple and low-cost platform technology for producing pexiganan antimicrobial peptide in E. coli. Biotechnology and Bioengineering, 112 5: 957-964. doi:10.1002/bit.25505

Sustained release of fipronil insecticide in Vitro and in Vivo from biocompatible silica nanocapsules

Wibowo, David, Zhao, Chun-Xia, Peters, Brenton C. and Middelberg, Anton P. J. (2014) Sustained release of fipronil insecticide in Vitro and in Vivo from biocompatible silica nanocapsules. Journal of Agricultural and Food Chemistry, 62 52: 12504-12511. doi:10.1021/jf504455x

Titania microparticles using a facile microfluidic mass-transfer control method

Zhao, Chun-Xia and Middelberg, Anton P. J. (2014) Titania microparticles using a facile microfluidic mass-transfer control method. Chemical Engineering Science, 112 10-14. doi:10.1016/j.ces.2014.03.009

Nanoparticle vaccines

Zhao, Liang, Seth, Arjun, Wibowo, Nani, Zhao, Chun-Xia, Mitter, Neena, Yu, Chengzhong and Middelberg, Anton P. J. (2014) Nanoparticle vaccines. Vaccine, 32 3: 327-337. doi:10.1016/j.vaccine.2013.11.069

Emulsion-templated silica nanocapsules formed using bio-inspired silicification

Wibowo, David, Zhao, Chun-Xia and Middelberg, Anton P. J. (2014) Emulsion-templated silica nanocapsules formed using bio-inspired silicification. Chemical Communications, 50 77: 11325-11328. doi:10.1039/c4cc04904g

Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery

Zhao, Chun-Xia (2013) Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery. Advanced Drug Delivery Reviews, 65 11-12: 1420-1446. doi:10.1016/j.addr.2013.05.009

One-step fabrication of titania hollow spheres by controlled interfacial reaction in a droplet-based microfluidic system

Zhao, Chun-Xia and Middelberg, Anton P. J. (2013) One-step fabrication of titania hollow spheres by controlled interfacial reaction in a droplet-based microfluidic system. Microfluidics and Nanofluidics, 14 3-4: 703-709. doi:10.1007/s10404-012-1088-2

Magnetic mesoporous silica nanoparticles end-capped with hydroxyapatite for pH-responsive drug release

Zhao, Chun-Xia, Yu, Lei and Middelberg, Anton P. J. (2013) Magnetic mesoporous silica nanoparticles end-capped with hydroxyapatite for pH-responsive drug release. Journal of Materials Chemistry B, 1 37: 4828-4833. doi:10.1039/c3tb20641f

Microfluidic synthesis of monodisperse hierarchical silica particles with raspberry-like morphology

Zhao, Chun-Xia and Middelberg, Anton P. J. (2013) Microfluidic synthesis of monodisperse hierarchical silica particles with raspberry-like morphology. RSC Advances, 3 44: 21227-21230. doi:10.1039/c3ra42362j

Development of a group contribution method for determination of thermal conductivity of ionic liquids

We, Ke-Jun, Zhao, Chun-Xia and He, Chao-Hong (2012) Development of a group contribution method for determination of thermal conductivity of ionic liquids. Fluid Phase Equilibria, 339 10-14. doi:10.1016/j.fluid.2012.11.024

Investigation of convective heat transfer with liquids in microtubes

Wu, Ke-Jun, Zhao, Chun-Xia and He, Chao-Hong (2012) Investigation of convective heat transfer with liquids in microtubes. Industrial & Engineering Chemistry Research, 51 27: 9386-9395. doi:10.1021/ie301174j

A simple corresponding-states group contribution method for estimating surface tension of ionic liquids

We, Ke-Jun, Zhao, Chun-Xia and Chao-Hong He (2012) A simple corresponding-states group contribution method for estimating surface tension of ionic liquids. Fluid Phase Equilibria, 328 42-48. doi:10.1016/j.fluid.2012.05.021

Microfluidic elucidation of the effects of interfacial rheology on droplet deformation

Zhao, Chun-Xia, Rondeau, Elisabeth, Cooper-White, Justin J. and Middelberg, Anton P. J. (2012) Microfluidic elucidation of the effects of interfacial rheology on droplet deformation. Industrial and Engineering Chemistry Research, 51 4: 2021-2029. doi:10.1021/ie200631m

Design of low-charge peptide sequences for high-yield formation of titania nanoparticles

Zhao, Chun-Xia, Yu, Lei and Middelberg, Anton P. J. (2012) Design of low-charge peptide sequences for high-yield formation of titania nanoparticles. RSC Advances, 2 4: 1292-1295. doi:10.1039/c2ra00726f

Effects of fluid-fluid interfacial elasticity on droplet formation in microfluidic devices

Zhao, Chun-Xia, Miller, Erik, Cooper-White, Justin J. and Middelberg, Anton P.J. (2011) Effects of fluid-fluid interfacial elasticity on droplet formation in microfluidic devices. AIChE Journal, 57 7: 1669-1677. doi:10.1002/aic.12382

Nanoparticle synthesis in microreactors

Zhao, Chun-Xia, He, Lizhong, Qiao, Shizhang and Middelberg, Anton P.J. (2011) Nanoparticle synthesis in microreactors. Chemical Engineering Science, 66 7: 1463-1479. doi:10.1016/j.ces.2010.08.039

Two-phase microfluidic flows

Zhao, Chun-Xia and Middelberg, Anton P. J. (2011) Two-phase microfluidic flows. Chemical Engineering Science, 66 7: 1394-1411. doi:10.1016/j.ces.2010.08.038

Imaging the effects of peptide bio-surfactants on droplet deformation in a Taylor-Couette shear cell

Fridjonsson, Einar O., Chandrasekera, Thusara C., Sederman, Andrew J., Johns, Michael L., Zhao, Chun-Xia and Middelberg, Anton P. J. (2011) Imaging the effects of peptide bio-surfactants on droplet deformation in a Taylor-Couette shear cell. Soft Matter, 7 6: 2961-2967. doi:10.1039/c0sm00951b

Mass transfer and separation criteria for high-speed countercurrent chromatography

Zhao, Chun-Xia and He, Chao-Hong (2011) Mass transfer and separation criteria for high-speed countercurrent chromatography. AIChE Journal, 57 2: 359-372. doi:10.1002/aic.12282

A nonlinear active learning based on AUC optimization and its application to obstacle detection

Han, Guang, Zhao, Chunxia and Hu, Xuelei (2010) A nonlinear active learning based on AUC optimization and its application to obstacle detection. Jiqiren, 32 3: 344-351. doi:10.3724/SP.J.1218.2010.00344

Microfluidic mass-transfer control for the simple formation of complex multiple emulsions

Zhao, Chun-Xia and Middelberg, Anton P. J. (2009) Microfluidic mass-transfer control for the simple formation of complex multiple emulsions. Angewandte Chemie-International Edition, 48 39: 7208-7211. doi:10.1002/anie.200902485

Axial dispersion coefficient in high-speed counter-current chromatography

Zhao, Chun-Xia, Xua, Ya-Lan and He, Chao-Hong (2009) Axial dispersion coefficient in high-speed counter-current chromatography. Journal of Chromatography A, 1216 24: 4841-4846. doi:10.1016/j.chroma.2009.04.020

Densities and viscosities of binary mixtures of tri-n-butyl phosphate + cyclohexane, + n-heptane at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K

Fang, Sheng, Zhao, Chun-Xia and He, Chao-Hong (2008) Densities and viscosities of binary mixtures of tri-n-butyl phosphate + cyclohexane, + n-heptane at T = (288.15, 293.15, 298.15, 303.15, and 308.15) K. Journal of Chemical and Engineering Data, 53 9: 2244-2246. doi:10.1021/je8003707

Densities and viscosities of binary mixtures of tris(2-ethylhexyl) phosphate + cyclohexane or n-hexane at T = (293.15, 298.15, and 303.15) K and p = 0.1 MPa

Fang, Sheng, Zhao, Chun-Xia, He, Chao-Hong, Liu, Jian-Qing and Sun, Jiang-Hao (2008) Densities and viscosities of binary mixtures of tris(2-ethylhexyl) phosphate + cyclohexane or n-hexane at T = (293.15, 298.15, and 303.15) K and p = 0.1 MPa. Journal of Chemical and Engineering Data, 53 11: 2718-2720. doi:10.1021/je8006138

Retention of the stationary phase for high-speed countercurrent chromatography

He, Chao-Hong and Zhao, Chun-Xia (2007) Retention of the stationary phase for high-speed countercurrent chromatography. AIChE Journal, 53 6: 1460-1471. doi:10.1002/aic.11185

Sample capacity in preparative high-speed counter-current chromatography

Zhao, Chun-Xia and He, Chao-Hong (2007) Sample capacity in preparative high-speed counter-current chromatography. Journal of chromatography. A, 1146 2: 186-192. doi:10.1016/j.chroma.2007.01.105

Solubility of Atractylenolide III in Hexane, Ethyl Acetate, Diethyl Ether, and Ethanol from (283.2 to 323.2) K

Zhao, Chun-Xia and He, Chao-Hong (2007) Solubility of Atractylenolide III in Hexane, Ethyl Acetate, Diethyl Ether, and Ethanol from (283.2 to 323.2) K. Journal of Chemical and Engineering Data, 52 4: 1223-1225. doi:10.1021/je6005482

Preparative isolation and purification of atractylon and atractylenolide III from the Chinese medicinal plant Atractylodes macrocephala by high-speed counter-current chromatography

Zhao, Chunxia and He, Chaohong (2006) Preparative isolation and purification of atractylon and atractylenolide III from the Chinese medicinal plant Atractylodes macrocephala by high-speed counter-current chromatography. Journal of Separation Science, 29 11: 1630-1636. doi:10.1002/jssc.200500464

Bio-inspired nanomaterials for controlled release

Zhao, Chun-Xia, Wibowo, David and Middelberg, Anton P. J. (2015). Bio-inspired nanomaterials for controlled release. In: 2015 AIChE Annual Meeting, Salt Lake City, UT, United States, (). 8-13 November 2015.

Double emulsions by a one-step solvent shift method

Zhao, Chun-Xia and Middelberg, Anton P. J. (2010). Double emulsions by a one-step solvent shift method. In: Chemeca2010. 40th Annual Australasian Chemical and Process Engineering Conference, Adelaide, SA, Australia, (432-440). 26-29 September 2010.

Interfacial elasticity affects droplet formation in microfluidic channels

Zhao, Chun-Xia, Miller, Erik, Cooper-White, Justin J., Dexter, Annette F. and Middelberg, Anton P. J. (2009). Interfacial elasticity affects droplet formation in microfluidic channels. In: 8th World Congress of Chemical Engineering, Montreal, Canada, (). 23 - 27 August, 2009.

The influence of interfacial viscoelasticity on droplet deformation in microchannels

Zhao, Chun-Xia, Rondeau, Elisabeth, Miller, Erik, Cooper-White, Justin J., Dexter, Annette F. and Middelberg, Anton P.J. (2009). The influence of interfacial viscoelasticity on droplet deformation in microchannels. In: WCCE8: 8th World Congress of Chemical Engineering, Montréal, QC, Canada, (1-2). 23-27 August 2009.

Separation for the mixture of petroleum ether (60-90?) and ethyl acetate

Luo, D. Z., Zhao, C. X. and He, C. H. (2005). Separation for the mixture of petroleum ether (60-90?) and ethyl acetate. In: China/USA/Japan Joint Chemical Engineering Conference, Beijing, (). Oct 11-13, 2005.