Associate Professor Lata Vadlamudi

Principal Research Fellow

UQ Centre for Clinical Research
Faculty of Medicine
l.vadlamudi@uq.edu.au
+61 7 334 65034

Overview

Associate Professor Lata Vadlamudi has been a researcher in the field of epilepsy since 2002 and has been a neurologist in clinical practice since 2000. Associate Professor Lata Vadlamudi is a senior Staff Specialist in Neurology at the Royal Brisbane and Women’s Hospital and Group Leader at the UQ Centre for Clinical Research.

Epilepsy is one of the most common neurological disorders affecting over 50 million people worldwide and is characterised by the occurrence of seizures. One in 26 people will develop epilepsy during their lifetime. Despite more than 20 anti-epileptic medications, more than 30% of patients are not able to control their seizures with anti-epileptic medications.

The research is focused on answering two of the most difficult clinical questions that neurologists struggle to answer in the epilepsy clinic – “What is the cause of my epilepsy” and “How can my epilepsy be treated?”.

Current research interests include:

(1) Genomic and epigenomic landscapes of epilepsy, in order to expand our understanding of the cause of this complex disease.

(2) Integrating of genomics into clinical practice, in order to improve patient care and facilitate precision-based treatment choices.

Qualifications

  • Doctor of Philosophy, University of Melbourne
  • Fellow, Royal Australian College of Physicians
  • Fellow, Royal Australian College of General Practitioners
  • Bachelor of Medicine Bachelor of Surgery, The University of Queensland

Publications

  • Mohandas, Namitha, Loke, Yuk Jing, Mackenzie, Lisa, Bennett, Carmen, Berkovic, Samuel F., Craig, Jeffrey M. and Vadlamudi, Lata (2019) Deciphering the role of epigenetics in self-limited epilepsy with centrotemporal spikes. Epilepsy Research, 156 106163. doi:10.1016/j.eplepsyres.2019.106163

  • Mohandas, Namitha, Loke, Yuk Jing, Hopkins, Stephanie, Mackenzie, Lisa, Bennett, Carmen, Berkovic, Samuel F., Vadlamudi, Lata and Craig, Jeffrey M. (2019) Evidence for type-specific DNA methylation patterns in epilepsy: a discordant monozygotic twin approach. Epigenomics, . doi:10.2217/epi-2018-0136

  • Zhang, Yue-Hua, Burgess, Rosemary, Malone, Jodie P., Glubb, Georgie C., Helbig, Katherine L., Vadlamudi, Lata, Kivity, Sara, Afawi, Zaid, Bleasel, Andrew, Grattan-Smith, Padraic, Grinton, Bronwyn E., Bellows, Susannah T., Vears, Danya F., Damiano, John A., Goldberg-Stern, Hadassa, Korczyn, Amos D., Dibbens, Leanne M., Ruzzo, Elizabeth K., Hildebrand, Michael S., Berkovic, Samuel F. and Scheffer, Ingrid E. (2017) Genetic epilepsy with febrile seizures plus: refining the spectrum. Neurology, 89 12: 1210-1219. doi:10.1212/WNL.0000000000004384

View all Publications

Publications

Journal Article

Conference Publication

  • Dibbens, L. M., Scheffer, I. E., Regan, B. M., Mandelstam, S., Crompton, D. E., Hodgson, B. L., Licchetta, L., Provini, F., Bisulli, F., Vadlamudi, L., Gecz, J., Connelly, A., Tinuper, P., Ricos, M. G., Berkovic, S. F. and Heron, S. E. (2014). Mutations in Depdc5 Are a Major Cause of Lesional and Non-Lesional Focal Epilepsy. In: 11th European Congress on Epileptology, Stockholm, Sweden, (11-11). Jun 29-Jul 03, 2014. doi:10.1111/epi.12675

PhD and MPhil Supervision

Completed Supervision