Dr Sara Thygesen

Postdoctoral Research Fellow

School of Chemistry and Molecular Biosciences
Faculty of Science
s.thygesen@uq.edu.au
+61 7 336 59769

Overview

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Science (Microbiology), The University of Queensland

Publications

  • Thygesen, Sara Judith, Sester, David P. and Stacey, Katryn J. (2017). NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages. In: 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa, Japan, (49-50). 29 October - 2 November 2017. doi:10.1016/j.cyto.2017.09.010

  • Thygesen, Sara J., Sester, David P., Cridland, Simon O., Wilton, Steve D. and Stacey, Katryn J. (2016) Correcting the NLRP3 inflammasome deficiency in macrophages from autoimmune NZB mice with exon skipping antisense oligonucleotides. Immunology and Cell Biology, 94 5: 520-524. doi:10.1038/icb.2016.3

  • Sester, David P., Zamoshnikova, Alina, Thygesen, Sara J., Vajjhala, Parimala R., Cridland, Simon O., Schroder, Kate and Stacey, Katryn J. (2016). Assessment of inflammasome formation by flow cytometry. In Coligan, John E., Bierer, Barbara, Margulies, David H., Shevach, Ethan M. and Strober, Warren (Ed.), Current protocols in immunology (pp. 14.40.1-14.40.29) Hoboken, NJ United States: John Wiley & Sons. doi:10.1002/cpim.13

View all Publications

Publications

Book Chapter

  • Sester, David P., Zamoshnikova, Alina, Thygesen, Sara J., Vajjhala, Parimala R., Cridland, Simon O., Schroder, Kate and Stacey, Katryn J. (2016). Assessment of inflammasome formation by flow cytometry. In Coligan, John E., Bierer, Barbara, Margulies, David H., Shevach, Ethan M. and Strober, Warren (Ed.), Current protocols in immunology (pp. 14.40.1-14.40.29) Hoboken, NJ United States: John Wiley & Sons. doi:10.1002/cpim.13

Journal Article

  • Thygesen, Sara J., Sester, David P., Cridland, Simon O., Wilton, Steve D. and Stacey, Katryn J. (2016) Correcting the NLRP3 inflammasome deficiency in macrophages from autoimmune NZB mice with exon skipping antisense oligonucleotides. Immunology and Cell Biology, 94 5: 520-524. doi:10.1038/icb.2016.3

  • Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015) Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 3: 1233-1241. doi:10.4049/jimmunol.1402859

  • Sester, David P., Thygesen, Sara J., Sagulenko, Vitaliya, Vajjhala, Parimala R., Cridland, Jasmyn A., Vitak, Nazarii, Chen, Kaiwen W., Osborne, Geoffrey W., Schroder, Kate and Katryn J. Stacey (2015) A novel flow cytometric method to assess inflammasome formation. The Journal of Immunology, 194 1: 455-462. doi:10.4049/jimmunol.1401110

  • Sagulenko, V., Thygesen, S. J., Sester, D. P., Idris, A., Cridland, J. A., Vajjhala, P. R., Roberts, T., Schroder, K., Vince, J. E., Hill, J. M., Silke, J. and Stacey, K. J. (2013) AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death and Differentiation, 20 9: 1149-1160. doi:10.1038/cdd.2013.37

  • Yin, Qian, Sester, David P., Tian, Yuan, Hsiao, Yu-Shan, Lu, Alvin, Cridland, Jasmyn A., Sagulenko, Vitaliya, Thygesen, Sara J., Choubey, Divaker, Hornung, Veit, Walz, Thomas, Stacey, Katryn J. and Wu, Hao (2013) Molecular mechanism for p202-mediated specific inhibition of aim2 inflammasome activation. Cell Reports, 4 2: 327-339. doi:10.1016/j.celrep.2013.06.024

Conference Publication

  • Thygesen, Sara Judith, Sester, David P. and Stacey, Katryn J. (2017). NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages. In: 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa, Japan, (49-50). 29 October - 2 November 2017. doi:10.1016/j.cyto.2017.09.010

  • Stacey, K. J., Vajjhala, P. R., Sagulenko, V, Thygesen, S., Vitak, N. and Sester, D. P. (2016). Cytosolic DNA, HIN-200 proteins and inflammasome activation. In: International Congress of Immunology (ICI), Melbourne Australia, (501-501). 21-26 August 2016.

  • Thygesen, S. J., Sester, D. P., Sagulenko, V and Stacey, K. J. (2016). Inflammasome function in autoimmunity. In: International Congress of Immunology (ICI), Melbourne Australia, (1083-1083). 21-26 August 2016.