Dr Wei Wei

Postdoctoral Research Fellow

Queensland Brain Institute
w.wei@uq.edu.au
+61 7 334 66380

Overview

I am an early career researcher with about six years’ experience as a post-doctoral fellow. I completed my PhD in 2008 at the Graduate University of Chinese Academic Sciences (GUCAS) for Biochemistry and Molecular Biology. My research to date focuses on cognitive neuroepigenetics using a robust rodent model, with the aim of understanding the molecular underpinnings of fear-related memory disorders. In 2009, I moved to Australia and joined Associate Professor Tim Bredy’s lab at the Queensland Brain Institute, to start my research career in cognitive neuroscience. In 2014, I moved to the University of California, Irvine, as assistant project scienctist, with Dr Bredy. For family reasons, I decided to move back to QBI one year later, and helped Dr Bredy manage the lab when he was not present at QBI.

Research Interests

  • Neuroepigenetics in learning and memory
    My area of interest revolves around understanding the epigenetic processes influencing learning and memory and I have very strong expertise in epigenetics and molecular neuroscience. We use a variety of approaches in mice, including in vitro preparations, luciferase assay, chromatin immunoprecipitation, qPCR, lentiviral-mediated gene transfer, CRISPR/Cas9 based tools for neuroscience, FACS technique used for cell-type specific study, high-throughput DNA and RNA sequencing, and behavioural paradigms to address the issue of how memories are established and maintained across the lifespan.

Qualifications

  • Doctor of Natural Science, Chinese Acad.Sc.

Publications

  • Li, X. and Wei, W. (2017). Approaches to detecting DNA base modification in the brain. In DNA modifications in the brain (pp. 27-41) New York, NY, United States: Academic Press. doi:10.1016/B978-0-12-801596-4.00002-2

  • Widagdo, Jocelyn, Zhao, Qiong-Yi, Kempen, Marie-Jeanne, Tan, Men Chee, Ratnu, Vikram S., Wei, Wei, Leighton, Laura, Spadaro, Paola A., Edson, Janette, Anggono, Victor and Bredy, Timothy W. (2016) Experience-dependent accumulation of N6-methyladenosine in the prefrontal cortex is associated with memory processes in mice. Journal of Neuroscience, 36 25: 6771-6777. doi:10.1523/JNEUROSCI.4053-15.2016

  • Mitchnick, K., Wei, W., Creighton, S., Kalisch, B., Bredy, T. and Winters, B. (2015). Dissociable roles of GADD45A/B in the rat perirhinal cortex and hippocampus for object memory: different forms of dna methylation?. In: Special Issue: 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, (115-115). 23-27 August 2015. doi:10.1111/jnc.13188

View all Publications

Publications

Book Chapter

Journal Article

Conference Publication

  • Mitchnick, K., Wei, W., Creighton, S., Kalisch, B., Bredy, T. and Winters, B. (2015). Dissociable roles of GADD45A/B in the rat perirhinal cortex and hippocampus for object memory: different forms of dna methylation?. In: Special Issue: 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, (115-115). 23-27 August 2015. doi:10.1111/jnc.13188

  • Wei, W. (2015). Genetic knockdown of GADD45G inhibits fear memory. In: Special Issue: 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, (117-117). 23-27 August 2015. doi:10.1111/jnc.13188