Dr Allan McRae

NHMRC Career Development Fellow

Institute for Molecular Bioscience

Affil Research Fellow

Queensland Brain Institute
a.mcrae@imb.uq.edu.au
+61 7 334 66414

Overview

Qualifications

  • PhD, University of Edinburgh

Publications

  • Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017) Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 4: 418-428. doi:10.1002/mgg3.302

  • Elliott, Hannah R., Shihab, Hashem A., Lockett, Gabrielle A., Holloway, John W., McRae, Allan F., Smith, George Davey, Ring, Susan M., Gaunt, Tom R. and Relton, Caroline L. (2017) Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor. Diabetes, 66 6: 1713-1722. doi:10.2337/db16-0874

  • Hedman, Åsa K. , Mendelson, Michael M. , Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui , Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao , McRae, Allan F., Demissie, Serkalem, Shah, Sonia, Starr, John M., Cupples, L. Adrienne, Deloukas, Panos , Spector, Timothy D. , Sundstrom, Johan, Krauss, Ronald M. , Arnett, Donna K., Deary, Ian J. , Lind, Lars, Levy, Daniel and Ingelsson, Erik (2017) Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics, 10 1: . doi:10.1161/CIRCGENETICS.116.001487

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Master Philosophy

View all Supervision

Publications

Book Chapter

  • McRae, Allan F. (2017). Analysis of genome-wide association data. In Jonathan M. Keith (Ed.), Bioinformatics. Volume II: structure, function, and applications (pp. 161-173) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-6613-4_9

Journal Article

  • Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017) Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 4: 418-428. doi:10.1002/mgg3.302

  • Elliott, Hannah R., Shihab, Hashem A., Lockett, Gabrielle A., Holloway, John W., McRae, Allan F., Smith, George Davey, Ring, Susan M., Gaunt, Tom R. and Relton, Caroline L. (2017) Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor. Diabetes, 66 6: 1713-1722. doi:10.2337/db16-0874

  • Hedman, Åsa K. , Mendelson, Michael M. , Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui , Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao , McRae, Allan F., Demissie, Serkalem, Shah, Sonia, Starr, John M., Cupples, L. Adrienne, Deloukas, Panos , Spector, Timothy D. , Sundstrom, Johan, Krauss, Ronald M. , Arnett, Donna K., Deary, Ian J. , Lind, Lars, Levy, Daniel and Ingelsson, Erik (2017) Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics, 10 1: . doi:10.1161/CIRCGENETICS.116.001487

  • Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017) The genetic architecture of gene expression in peripheral blood. American Journal of Human Genetics, 100 2: 228-237. doi:10.1016/j.ajhg.2016.12.008

  • Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona, Pilling, Luke C., Pankow, James S., Tsao, Phil S., Liu, Chunyu, Zhao, Wei, Guarrera, Simonetta, Michopoulos, Vasiliki J., Smith, Alicia K., Peters, Marjolein J., Melzer, David, Vokonas, Pantel, Fornage, Myriam, Prokisch, Holger, Bis, Joshua C., Chu, Audrey Y., Herder, Christian, Grallert, Harald, Yao, Chen, Shah, Sonia, McRae, Allan F., Lin, Honghuang, Horvath, Steve, Fallin, Daniele, Hofman, Albert, Wareham, Nicholas J., Wiggins, Kerri L., Feinberg, Andrew P., Starr, John M., Visscher, Peter M., Murabito, Joanne M., Kardia, Sharon L. R., Absher, Devin M., Binder, Elisabeth B., Singleton, Andrew B., Bandinelli, Stefania, Peters, Annette, Waldenberger, Melanie, Matullo, Giuseppe, Schwartz, Joel D., Demerath, Ellen W., Uitterlinden, André G., Van Meurs, Joyce B. J., Franco, Oscar H., Chen, Yii-Der Ida, Levy, Daniel, Turner, Stephen T., Deary, Ian J., Ressler, Kerry J., Dupuis, Josée, Ferrucci, Luigi, Ong, Ken K., Assimes, Themistocles L., Boerwinkle, Eric, Koenig, Wolfgang, Arnett, Donna K., Baccarelli, Andrea A., Benjamin, Emelia J. and Dehghan, Abbas (2016) DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology, 17 1: . doi:10.1186/s13059-016-1119-5

  • Kassam, Irfahan, Lloyd-Jones, Luke, Holloway, Alexander, Small, Kerrin S., Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Gibson, Greg, Spector, Tim D., Esko, Tonu, Montgomery, Grant W., Powell, Joseph E., Yang, Jian, Visscher, Peter M. and McRae, Allan F. (2016) Autosomal genetic control of human gene expression does not differ across the sexes. Genome Biology, 17 1: 248.1-248.10. doi:10.1186/s13059-016-1111-0

  • Liu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H., Strauch, K., Peters, A., Visscher, P. M., Wray, N. R., Guo, X., Wiggins, K. L., Smith, A. K., Binder, E. B., Ressler, K. J., Irvin, M. R., Absher, D. M., Hernandez, D., Ferrucci, L., Bandinelli, S., Lohman, K., Ding, J., Trevisi, L., Gustafsson, S., Sandling, J. H., Stolk, L., Uitterlinden, A. G., Yet, I., Castillo-Fernandez, J. E., Spector, T. D., Schwartz, J. D., Vokonas, P., Lind, L., Li, Y., Fornage, M., Arnett, D. K., Wareham, N. J., Sotoodehnia, N., Ong, K. K., van Meurs, J. B. J., Conneely, K. N., Baccarelli, A. A., Deary, I. J., Bell, J. T., North, K. E., Liu, Y., Waldenberger, M., London, S. J., Ingelsson, E. and Levy, D. (2016) A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, . doi:10.1038/mp.2016.192

  • Kassam, Irfahan, Qi, Tuan, Lloyd-Jones, Luke, Holloway, Alexander, Bonder, Marc Jan, Henders, Anjali K., Martin, Nicholas G., Powell, Joseph E., Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and McRae, Allan F. (2016) Evidence for mitochondrial genetic control of autosomal gene expression. Human Molecular Genetics, 25 24: 5332-5338. doi:10.1093/hmg/ddw347

  • Joehanes, Roby, Just, Allan C., Marioni, Riccardo E., Pilling, Luke C., Reynolds, Lindsay M., Mandaviya, Pooja R., Guan, Weihua, Xu, Tao, Elks, Cathy E., Aslibekyan, Stella, Moreno-Macias, Hortensia, Smith, Jennifer A., Brody, Jennifer A., Dhingra, Radhika, Yousefi, Paul, Pankow, James S., Kunze, Sonja, Shah, Sonia H., McRae, Allan F., Lohman, Kurt, Sha, Jin, Absher, Devin M., Ferrucci, Luigi, Zhao, Wei, Demerath, Ellen W., Bressler, Jan, Grove, Megan L., Huan, Tianxiao, Liu, Chunyu, Mendelson, Michael M., Yao, Chen, Kiel, Douglas P., Peters, Annette, Wang-Sattler, Rui, Visscher, Peter M., Wray, Naomi R., Starr, John M., Ding, Jingzhong, Rodriguez, Carlos J., Wareham, Nicholas J., Irvin, Marguerite R., Zhi, Degui, Barrdahl, Myrto, Vineis, Paolo, Ambatipudi, Srikant, Uitterlinden, André G., Hofman, Albert, Schwartz, Joel, Colicino, Elena, Hou, Lifang, Vokonas, Pantel S., Hernandez, Dena G., Singleton, Andrew B., Bandinelli, Stefania, Turner, Stephen T., Ware, Erin B., Smith, Alicia K., Klengel, Torsten, Binder, Elisabeth B., Psaty, Bruce M., Taylor, Kent D., Gharib, Sina A., Swenson, Brenton R., Liang, Liming, Demeo, Dawn L., O'Connor, George T., Herceg, Zdenko, Ressler, Kerry J., Conneely, Karen N., Sotoodehnia, Nona, Kardia, Sharon L. R., Melzer, David, Baccarelli, Andrea A., Van Meurs, Joyce B. J., Romieu, Isabelle, Arnett, Donna K., Ong, Ken K., Liu, Yongmei, Waldenberger, Melanie, Deary, Ian J., Fornage, Myriam, Levy, Daniel and London, Stephanie J. (2016) Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics, 9 5: 436-447. doi:10.1161/CIRCGENETICS.116.001506

  • Bakshi, Andrew, Zhu, Zhihong, Vinkhuyzen, Anna A. E., Hill, W. David, Mcrae, Allan F., Visscher, Peter M. and Yang, Jian (2016) Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. Scientific Reports, 6 . doi:10.1038/srep32894

  • Kassam, Irfahan and McRae, Allan F. (2016) The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes. Genome Biology, 17 1: . doi:10.1186/s13059-016-1035-8

  • Pavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, Mcrae, Allan F., Wray, Naomi R. and Yang, Jian (2016) Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine, 8 1: . doi:10.1186/s13073-016-0338-4

  • Mbarek, Hamdi, Steinberg, Stacy, Nyholt, Dale R., Gordon, Scott D., Miller, Michael B., McRae, Allan F, Hottenga, Jouke Jan, Day, Felix R., Willemsen, Gonneke, de Geus, Eco J., Davies, Gareth E, Martin, Hilary C, Penninx, Brenda W, Jansen, Rick, McAloney, Kerrie, Vink, Jacqueline M., Kaprio, Jaakko, Plomin, Robert, Spector, Tim D., Magnusson, Patrik K., Reversade, Bruno, Harris, R. Alan, Aagaard, Kjersti, Kristjansson, Ragnar P., Olafsson, Isleifur, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Iacono, William G., Lambalk, Cornelis B, Montgomery, Grant W., McGue , Matt, Ong, Ken K., Perry, John R.B., Martin, Nicholas G., Stefansson, Hreinn, Stefansson, Kari and Boomsman, Dorret I. (2016) Identification of common genetic variants influencing spontaneous dizygotic twinning and female fertility. American Journal of Human Genetics, 98 5: 898-908. doi:10.1016/j.ajhg.2016.03.008

  • Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016) The epigenetic clock and telomere length are independently associated with chronological age and mortality. International Journal of Epidemiology, 45 2: 424-432. doi:10.1093/ije/dyw041

  • Shakhbazov, Konstantin, Powell, Joseph E., Hemani, Gibran, Henders, Anjali K., Martin, Nicholas G., Visscher, Peter M., Montgomery, Grant W. and McRae, Allan F. (2016) Shared genetic control of expression and methylation in peripheral blood. BMC Genomics, 17 1: . doi:10.1186/s12864-016-2498-4

  • Tseng, Hsu-Wen, Pitt, Miranda E., Glant, Tibor T., McRae, Allan F., Kenna, Tony J., Brown, Matthew A., Pettit, Allison R. and Thomas, Gethin P. (2016) Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes. Arthritis Research and Therapy, 18 1: . doi:10.1186/s13075-015-0805-0

  • Chen, Brian H., Marioni, Riccardo E., Colicino, Elena, Peters, Marjolein J., Ward-Caviness, Cavin K., Tsai, Pei-Chien, Roetker, Nicholas S., Just, Allan C., Demerath, Ellen W., Guan, Weihua, Bressler, Jan, Fornage, Myriam, Studenski, Stephanie, Vandiver, Amy R., Moore, Ann Zenobia, Tanaka, Toshiko, Kiel, Douglas P., Liang, Liming, Vokonas, Pantel, Schwartz, Joel, Lunetta, Kathryn L., Murabito, Joanne M., Bandinelli, Stefania, Hernandez, Dena G., Melzer, David, Nalls, Michael, Pilling, Luke C., Price, Timothy R., Singleton, Andrew B., Gieger, Christian, Holle, Rolf, Kretschmer, Anja, Kronenberg, Florian, Kunze, Sonja, Linseisen, Jakob, Meisinger, Christine, Rathmann, Wolfgang, Waldenberger, Melanie, Visscher, Peter M., Shah, Sonia, Wray, Naomi R., McRae, Allan F., Franco, Oscar H., Hofman, Albert, Uitterlinden, Andre G., Absher, Devin, Assimes, Themistocles, Levine, Morgan E., Lu, Ake T., Tsao, Philip S., Hou, Lifang, Manson, JoAnn E., Carty, Cara L., LaCroix, Andrea Z., Reiner, Alexander P., Spector, Tim D., Feinberg, Andrew P., Levy, Daniel, Baccarelli, Andrea, van Meurs, Joyce, Bell, Jordana T., Peters, Annette, Deary, Ian J., Pankow, James S., Ferrucci, Luigi and Horvath, Steve (2016) DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging, 8 9: 1844-1865. doi:10.18632/aging.101020

  • Bui, Masato, Benyamin, Beben, Shah, Sonia, Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W. and McRae, Allan F. (2015) Sharing a placenta is associated with a greater similarity in DNA methylation in monochorionic versus dichorionic twin pars in blood at age 14. Twin Research and Human Genetics, 18 6: 680-685. doi:10.1017/thg.2015.87

  • Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Tukiainen, Taru, Ramos, Yolande F., Goring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., De Jager, Philip L., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, Andre G., Rivadeneira, Fernando, Van Rooij, Jeroen, Stolk, Lisette, Broer, Linda, Verbiest, Michael M. P. J., Jhamai, Mila, Arp, Pascal, Metspalu, Andres, Tserel, Liina, Milani, Lili, Samani, Nilesh J., Peterson, Part, Kasela, Silva, Codd, Veryan, Peters, Annette, Ward-Caviness, Cavin K., Herder, Christian, Waldenberger, Melanie, Roden, Michael, Singmann, Paula, Zeilinger, Sonja, Illig, Thomas, Homuth, Georg, Grabe, Hans-Jorgen, Volzke, Henry, Steil, Leif, Kocher, Thomas, Murray, Anna, Melzer, David, Yaghootkar, Hanieh, Bandinelli, Stefania, Moses, Eric K., Kent, Jack W., Curran, Joanne E., Johnson, Matthew P., Williams-Blangero, Sarah, Westra, Harm-Jan, McRae, Allan F., Smith, Jennifer A., Kardia, Sharon L. R., Hovatta, Iiris, Perola, Markus, Ripatti, Samuli, Salomaa, Veikko, Henders, Anjali K., Martin, Nicholas G., Smith, Alicia K., Mehta, Divya, Binder, Elisabeth B., Nylocks, K. Maria, Kennedy, Elizabeth M., Klengel, Torsten, Ding, Jingzhong, Suchy-Dicey, Astrid M., Enquobahrie, Daniel A., Brody, Jennifer, Rotter, Jerome I., Chen, Yii-Der I., Houwing-Duistermaat, Jeanine, Kloppenburg, Margreet, Slagboom, P. Eline, Helmer, Quinta, Den Hollander, Wouter, Bean, Shannon, Raj, Towfique, Bakhshi, Noman, Wang, Qiao Ping, Oyston, Lisa J., Psaty, Bruce M., Tracy, Russell P., Montgomery, Grant W., Turner, Stephen T., Blangero, John, Meulenbelt, Ingrid, Ressler, Kerry J., Yang, Jian, Franke, Lude, Kettunen, Johannes, Visscher, Peter M., Neely, G. Gregory, Korstanje, Ron, Hanson, Robert L., Prokisch, Holger, Ferrucci, Luigi, Esko, Tonu, Teumer, Alexander, Van Meurs, Joyce B. J., Johnson, Andrew D., Nalls, Michael A., Hernandez, Dena G., Cookson, Mark R., Gibbs, Raphael J., Hardy, John, Ramasamy, Adaikalavan, Zonderman, Alan B., Dillman, Allissa, Traynor, Bryan, Smith, Colin, Longo, Dan L., Trabzuni, Daniah, Troncoso, Juan, Van Der Brug, Marcel, Weale, Michael E., O'Brien, Richard, Johnson, Robert, Walker, Robert, Zielke, Ronald H., Arepalli, Sampath, Ryten, Mina, Singleton, Andrew B. and NABEC/UKBEC Consortium (2015) The transcriptional landscape of age in human peripheral blood. Nature Communications, 6 8570.1-8570.14. doi:10.1038/ncomms9570

  • Howrigan, D.P., Simonson, M.A., Davies, G., Harris, S.E., Tenesa, A., Starr, J.M., Liewald, D.C., Deary, I.J., McRae, A., Wright, M.J., Montgomery, G.W., Hansell, N., Martin, N.G., Payton, A., Horan, M., Ollier, W.E., Abdellaoui, A., Boomsma, D.I., DeRosse, P., Knowles, E.E.M., Glahn, D.C., Djurovic, S., Melle, I., Andreassen, O.A., Christoforou, A., Steen, V.M., Hellard, S.L., Sundet, K., Reinvang, I., Espeseth, T., Lundervold, A.J., Giegling, I., Konte, B., Hartmann, A.M., Rujescu, D., Roussos, P., Giakoumaki, S., Burdick, K.E., Bitsios, P., Donohoe, G., Corley, R.P., Visscher, P.M., Pendleton, N., Malhotra, A.K., Neale, B.M., Lencz, T. and Keller, M.C. (2015) Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry, 21 6: 837-843. doi:10.1038/mp.2015.120

  • Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Ritchie, Stuart J., Muniz-Terrera, Graciela, Harris, Sarah E., Gibson, Jude, Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Taylor, Adele, Murphy, Lee, Starr, John M., Horvath, Steve, Visscher, Peter M., Wray, Naomi R. and Deary, Ian J. (2015) The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology, 44 4: 1388-1396. doi:10.1093/ije/dyu277

  • Shah, Sonia, Bonder, Marc J., Marioni, Riccardo E., Zhu, Zhihong, McRae, Allan F., Zhernakova, Alexandra, Harris, Sarah E., Liewald, Dave, Henders, Anjali K., Mendelson, Michael M., Liu, Chunyu, Joehanes, Roby, Liang, Liming, Levy, Daniel, Martin, Nicholas G., Starr, John M., Wijmenga, Cisca, Wray, Naomi R., Yang, Jian, Montgomery, Grant W., Franke, Luke, Deary, Ian J., Visscher, Peter M. and BIOS Consortium (2015) Improving phenotypic prediction by combining genetic and epigenetic associations. American Journal of Human Genetics, 97 1: 75-85. doi:10.1016/j.ajhg.2015.05.014

  • Goldinger, Anita, Shakhbazov, Konstantin, Henders, Anjali K., McRae, Allan F., Montgomery, Grant W. and Powell, Joseph E. (2015) Seasonal effects on gene expression. PLoS ONE, 10 5: 1-16. doi:10.1371/journal.pone.0126995

  • Mcrae, Allan F, Visscher, Peter, M, Montgomery, Grant W and Martin, Nicholas G (2015) Large autosomal copy-number differences within unselected monozygotic twin pairs are rare. Twin Research and Human Genetics, 18 1: 13-18. doi:10.1017/thg.2014.85

  • Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Chen, Brian H., Colicino, Elena, Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Feinberg, Andrew P., Fallin, M. Daniele, Multhaup, Michael L., Jaffe, Andrew E., Joehanes, Roby, Schwartz, Joel, Just, Allan C., Lunetta, Kathryn L., Murabito, Joanne M., Starr, John M., Horvath, Steve, Baccarelli, Andrea A., Levy, Daniel, Visscher, Peter M., Wray, Naomi R. and Deary, Ian J. (2015) DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology, 16 1: 25.1-25.12. doi:10.1186/s13059-015-0584-6

  • Shah, Sonia, McRae, Allan F., Marioni, Riccardo E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Starr, John M., Wray, Naomi R., Deary, Ian J. and Visscher, Peter M. (2014) Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research, 24 11: 1725-1733. doi:10.1101/gr.176933.114

  • Hemani, Gibran, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Yang, Jian, Gibson, Greg, Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and Powell, Joseph E. (2014) Another explanation for apparent epistasis: reply. Nature, 514 7520: E5-E6. doi:10.1038/nature13692

  • McRae, Allan F., Powell, Joseph E., Henders, Anjali K., Bowdler, Lisa, Hemani, Gibran, Shah, Sonia, Painter, Jodie N., Martin, Nicholas G., Visscher, Peter M. and Montgomery, Grant W. (2014) Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biology, 15 5: 1-10. doi:10.1186/gb-2014-15-5-r73

  • Hemani, Gibran, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Yang, Jian, Gibson, Greg, Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and Powell, Joseph E. (2014) Detection and replication of epistasis influencing transcription in humans. Nature, 508 7495: 249-253. doi:10.1038/nature13005

  • Derks, Eske M., Ayub, Muhammad, Chambert, Kimberly, Del Favero, Jurgen, Johnstone, Mandy, Macgregor, Stuart, Maclean, Alan, McKechanie, Andrew G., McRae, Allan F., Moran, Jennifer L., Pickard, Benjamin S., Purcell, Shaun, Sklar, Pamela, St Clair, David M., Wray, Naomi R., Visscher, Peter M. and Blackwood, Douglas H. R. (2013) A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 162 8: 847-854. doi:10.1002/ajmg.b.32189

  • Thomson, P. A., Parla, J. S., McRae, A. F., Kramer, M., Ramakrushnan, K., Yao, J., Soares, D. C., McCarthy, S., Morris, S. W., Cardone, L., Cass, S., Ghiban, E., Hennah, W., Evans, K. L., Rebolini, D., Millar, J. K., Harris, S. E., Starr, J. M., MacIntyre, J., Generation Scotland, McIntosh, A. M., Watson, J. D., Deary, I. J., Visscher, P. M., Blackwood, D. H., McCombie, W. R. and Porteous, D. J. (2013) 708 common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. Molecular Psychiatry, Advance online publication 6: 1-8. doi:10.1038/mp.2013.68

  • McRae, Allan F., Richter, Melinda M. and Lind, Penelope A. (2013) Case-control association testing of common variants from sequencing of DNA pools. PLoS One, 8 6: e65410.1-e65410.4. doi:10.1371/journal.pone.0065410

  • Byrne, E. M., Carrillo-Roa, T., Henders, A. K., Bowdler, L., McRae, A. F., Heath, A. C., Martin, N. G., Montgomery, G. W., Krause, L. and Wray, N. R. (2013) Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin. Translational Psychiatry, 3 e269.1-e269.6. doi:10.1038/tp.2013.45

  • Powell, Joseph E., Henders, Anjali K., McRae, Allan F., Kim, Jinhee, Hemani, Gibran, Martin, Nicholas G., Dermitzakis, Emmanouil T., Gibson, Greg, Montgomery, Grant W. and Visscher, Peter M. (2013) Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data. PLoS Genetics, 9 5: e1003502.1-e1003502.10. doi:10.1371/journal.pgen.1003502

  • McRae, Allan F., Wright, Margaret J., Hansell, Narelle K., Montgomery, Grant W. and Martin, Nicholas G. (2013) No association between general cognitive ability and rare copy number variation. Behavior Genetics, 43 3: 202-207. doi:10.1007/s10519-013-9587-9

  • Goldinger, Anita, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Gibson, Greg, Montgomery, Grant W., Visscher, Peter M. and Powell, Joseph E. (2013) Genetic and nongenetic variation revealed for the principal components of human gene expression. Genetics, 195 3: 1117-1128. doi:10.1534/genetics.113.153221

  • Byrne, Enda M., Johnson, Julie, McRae, Allan F., Nyholt, Dale R., Medland, Sarah E., Gehrman, Philip R., Heath, Andrew C., Madden, Pamela A. F., Montgomery, Grant W., Chenevix-Trench, Georgia and Martin, Nicholas G. (2012) A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor. Sleep, 35 7: 967-975. doi:10.5665/sleep.1962

  • Powell, Joseph E., Henders, Anjali K., McRae, Allan F., Caracella, Anthony, Smith, Sara, Wright, Margaret J., Whitfield, John B., Dermitzakis, Emmanouil T., Martin, Nicholas G., Visscher, Peter M. and Montgomery, Grant W. (2012) The Brisbane systems genetics study: genetical genomics meets complex trait genetics. PLoS One, 7 4: e35430.1-e35430.9. doi:10.1371/journal.pone.0035430

  • Powell, Joseph E., Henders, Anjali K., McRae, Allan F., Wright, Margaret J., Martin, Nicholas G., Dermitzakis, Emmanouil T., Montgomery, Grant W. and Visscher, Peter M. (2012) Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Research, 22 456-466. doi:10.1101/gr.126540.111

  • Mosing, Miriam A., Medland, Sarah E., McRae, Allan, Landers, Joseph George, Wright, Margaret J. and Martin, Nicholas G. (2012) Genetic influences on life span and its relationship to personality: A 16-year follow-up study of a sample of aging twins. Psychosomatic Medicine, 74 1: 16-22. doi:10.1097/PSY.0b013e3182385784

  • Jablensky, A ., Angelicheva, D ., Donohoe, G. J., Cruickshank, M., Azmanov, D. N., Morris, D. W., McRae, A., Weickert, C. S., Carter, K. W., Chandler, D., Alexandrov, B., Usheva, A., Morar, B., Verbrugghe, P. L., Filipovska, A., Rackham, O., Bishop, A. R., Rasmussen, K. Ø., Dragovic, M., Cooper, M., Phillips, M., Badcock, J., Bramon-Bosch, E., Almeida, O. P., Flicker, L., Gill, M., Corvin, A., MacGregor, S. and Kalaydjieva, L. (2012) Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia. Molecular Psychiatry, 17 1328-1339. doi:10.1038/mp.2011.129

  • Luong, Hein T. T., Chaplin, Justin, McRae, Allan F., Medland, Sarah E., Willemsen, Gonneke, Nyholt, Dale R., Henders, Anjali K., Hoekstra, Chantal, Duffy, David L., Martin, Nicholas G., Boomsma, Dorret I., Montgomery, Grant W. and Painter, Jodie N. (2011) Variation in BMPR1B, TGFRB1 and BMPR2 and control of dizygotic twinning. Twin Research and Human Genetics, 14 5: 408-416. doi:10.1375/twin.14.5.408

  • Larsson, Mats, Duffy, David L., Zhu, Gu, Liu, Jimmy Z., Macgregor, Stuart, McRae, Allan F., Wright, Margaret J., Sturm, Richard A., Mackey, David A., Montgomery, Grant W., Martin, Nicholas G. and Medland, Sarah E. (2011) GWAS findings for human iris patterns: Associations with variants in genes that influence normal neuronal pattern development. American Journal of Human Genetics, 89 2: 334-343. doi:10.1016/j.ajhg.2011.07.011

  • Ferreira, Manuel A. R., McRae, Allan F., Medland, Sarah E., Nyholt, Dale R., Gordon, Scott D., Wright, Margaret J., Henders, Anjali K., Madden, Pamela A., Visscher, Peter M., Wray, Naomi R., Heath, Andrew C., Montgomery, Grant W., Duffy, David L. and Martin, Nicholas G. (2011) Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. European Journal of Human Genetics, 19 4: 458-464. doi:10.1038/ejhg.2010.191

  • Frank, Rene A. W., McRae, Allan F., Pocklington, Andrew J., van de Lagemaat, Louie N., Navarro, Pau, Croning, Mike D. R., Komiyama, Noboru H., Bradley, Sophie J., Challiss, R. A. John, Armstrong, J. Douglas, Finn, Robert D., Malloy, Mary P., MacLean, Alan W., Harris, Sarah E., Starr, John M., Bhaskar, Sanjeev S., Howard, Eleanor K., Hunt, Sarah E., Coffey, Alison J., Ranganath, Venkatesh, Deloukas, Panos, Rogers, Jane, Muir, Walter J., Deary, Ian J., Blackwood, Douglas H., Visscher, Peter M. and Grant, Seth G. N. (2011) Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS One, 6 4: e19011.1-e19011.9. doi:10.1371/journal.pone.0019011

  • Gratten, J., Wilson, A. J., McRae, A. F., Beraldi, D., Visscher, P. M., Pemberton, J. M. and Slate, J. (2010) No evidence for warming climate theory of coat colour change in Soay sheep: A comment on Maloney et al.. Biology Letters, 6 5: 678-679. doi:10.1098/rsbl.2010.0160

  • Sommerlad, Susan, McRae, Allan F., McDonald, Brenda, Johnstone, Isobel, Cuttell, Leigh, Seddon, Jennifer M. and O'Leary, Caroline A. (2010) Congenital sensorineural deafness in Australian Stumpy-tail Cattle Dogs is an autosomal recessive trait that maps to CFA10. PLoS One, 5 10: e13364. doi:10.1371/journal.pone.0013364

  • Liu, Jimmy Z., McRae, Allan F., Nyholt, Dale R., Medland, Sarah E., Wray, Naomi R., Brown, Kevin M., AMFS Investigators, Hayward, Nicholas K., Montgomery, Grant W., Visscher, Peter M., Martin, Nicholas G. and Macgregor, Stuart (2010) A versatile gene-based test for genome-wide association studies. American Journal of Human Genetics, 87 1: 139-145. doi:10.1016/j.ajhg.2010.06.009

  • Liu, Jimmy Z., Medland, Sarah E., Wright, Margaret J., Henders, Anjali K., Heath, Andrew C., Madden, Pamela A. F., Duncan, Alexis, Montgomery, Grant W., Martin, Nicholas G. and McRae, Allan F. (2010) Genome-wide association study of height and body mass index in Australian twin families. Twin Research And Human Genetics, 13 2: 179-193. doi:10.1375/twin.13.2.179

  • Johnston, S. E., Beraldi, D., McRae, A. F., Pemberton, J. M. and Slate, J. (2010) Horn type and horn length genes map to the same chromosomal region in Soay sheep. Heredity, 104 2: 196-205. doi:10.1038/hdy.2009.109

  • Medland, S, Nyholt, D, Painter, JN, McEnvoy, BP, Allan McRae, Zhu, G, Gordon, SD, Ferreira, MAR, Wright, MJ, Henders, AK, Campbell MJ, Duffy, D, Hansell, N K, Macgregor, S, Slutske, WS, Heath, AC, Montgomery, GW and Martin, NG (2009) Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans. American Journal of Human Genetics, 85 5: 750-755. doi:10.1016/j.ajhg.2009.10.009

  • E. M. Byrne, A. F. McRae, D. L. Duffy, Z. Z. Zhao, N. G. Martin, J. B. Whitfield, P. M. Visscher and G. W. Montgomery (2009) Family-based mitochondrial association study of traits related to type 2 diabetes and the metabolic syndrome in adolescents. Diabetologia, 52 11: 2359-2368. doi:10.1007/s00125-009-1510-9

  • Byrne, EM, McRae, AF, Duffy, DL, Zhao, ZZ, Martin, NG, Wright, MJ, Montgomery, GW and Visscher, PM (2009) Association Study of Common Mitochondrial Variants and Cognitive Ability. BEHAVIOR GENETICS, 39 5: 504-512. doi:10.1007/s10519-009-9276-x

  • Matthew C. Keller, Allan F. McRae, Julie M. McGaughran, Peter M. Visscher, Nicholas G. Martin and Grant W. Montgomery (2009) Non-pathological paternal isodisomy of chromosome 2 detected from a genome-wide SNP scan.. American Journal of Medical Genetics. Part A, 149A 8: 1823-1826. doi:10.1002/ajmg.a.32973

  • Brian P. McEvoy, Grant W. Montgomery, Allan F. McRae, Samuli Ripatti, Markus Perola, Tim D. Spector, Lynn Cherkas, Kourosh R. Ahmadi, Dorret Boomsma, Gonneke Willemsen, Jouke J. Hottenga, Nancy L. Pedersen, Patrik K.E. Magnusson, Kirsten Ohm Kyvik, Kaare Christensen, Jaakko Kaprio, Kauko Heikkilä, Aarno Palotie, Elisabeth Widen, Juha Muilu, Ann-Christine Syvänen, Ulrika Liljedahl, Orla Hardiman, Simon Cronin, Leena Peltonen, Nicholas G. Martin and Peter M. Visscher (2009) Geographical structure and differential natural selection among North European populations. Genome Research, 19 5: 804-814. doi:10.1101/gr.083394.108

  • Benyamin, Beben, Visscher, Peter M. and McRae, Allan F. (2009) Family-based genome-wide association studies. Pharmacogenomics, 10 2: 181-190. doi:10.2217/14622416.10.2.181

  • Zachary A Kaminsky, Thomas Tang, Sun-Chong Wang, Carolyn Ptak, Gabriel H T Oh, Albert H C Wong, Laura A Feldcamp, Carl Virtanen, Jonas Halfvarson, Curt Tysk, Allan F McRae, Peter M Visscher, Grant W Montgomery, Irving I Gottesman, Nicholas G Martin and Art Petronis (2009) DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics, 41 2: 240-245. doi:10.1038/ng.286

  • Beben Benyamin, Allan F. McRae, Gu Zhu, Scott Gordon, Anjali K. Henders, Aarno Palotie, Leena Peltonen, Nicholas G. Martin, Grant W. Montgomery, John B. Whitfield and Peter M. Visscher (2009) Variants in TF and HFE Explain 40% of Genetic Variation in Serum-Transferrin Levels. American Journal of Human Genetics, 84 1: 60-65. doi:10.1016/j.ajhg.2008.11.011

  • Knight, Helen M., Pickard, Benjamin S., Maclean, Alan, Malloy, Mary P., Soares, Dinesh C., McRae, Allan F., Condie, Alison, White, Angela, Hawkins, William, McGhee, Kevin, van Beck, Margaret, MacIntyre, Donald J., Starr, John M., Deary, Ian J., Visscher, Peter M., Porteous, David J., Cannon, Ronald E., St Clair, David, Muir, Walter J. and Blackwood, Douglas H. R. (2009) A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression. American Journal of Human Genetics, 85 6: 833-846. doi:10.1016/j.ajhg.2009.11.003

  • Sved, John A., McRae, Allan F. and Visscher, Peter M. (2008) Divergence between human populations estimated from linkage disequilibrium. American Journal of Human Genetics, 83 6: 737-743. doi:10.1016/j.ajhg.2008.10.019

  • Middelberg, Rita P., Gordon, Scott D., Zhu, Gu, McRae, Allan, Montgomery, Grant W., Martin, Nicholas G. and Whitfield, John B. (2008) Linkage and Association Analyses of Longitudinally Measured Lipid Phenotypes in Adolescence. Twin Research and Human Genetics, 11 6: 603-620. doi:10.1375/twin.11.6.603

  • Keith, Jonathan M., McRae, Allan, Duffy, David, Mengersen, Kerrie and Visscher, Peter M. (2008) Calculation of IBD probabilities with dense SNP or sequence data. Genetic Epidemiology, 32 6: 513-519. doi:10.1002/gepi.20324

  • McRae, Allan F., Byrne, Enda M., Zhao, Zhen Zhen, Montgomery, Grant W. and Visscher, Peter M. (2008) Power and SNP tagging in whole mitochondrial genome association studies. Genome Research, 18 6: 911-917. doi:10.1101/gr.074872.107

  • Gratten, J., Wilson, A. J., McRae, A. F., Beraldi, D., Visscher, P. M., Pemberton, J. M. and Slate, J. (2008) A localized negative genetic correlation constrains microevolution of coat color in wild sheep. Science, 319 5861: 318-320. doi:10.1126/science.1151182

  • Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M. and Pemberton, Josephine M. (2007) Mapping quantitative trait loci underlying fitness-related traits in a free-living sheep population. Evolution, 61 6: 1403-1416. doi:10.1111/j.1558-5646.2007.00106.x

  • Gratten, J., Beraldi, D., Lowder, B. V., McRae, A. F., Visscher, P. M., Pemberton, J. M. and Slate, J. (2007) Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proceedings of the Royal Society of London: Biological Sciences, 274 1610: 619-626. doi:10.1098/rspb.2006.3762

  • McRae, A. F., Matigian, N. A., Vadlamudi, L., Mulley, J. C., Mowry, B., Martin, N. G., Berkovic, S. F., Hayward, N. K. and Visscher, P. M. (2007) Replicated effects of sex and genotype on gene expression in human lymphoblastoid cell lines. Human Molecular Genetics, 16 4: 364-373. doi:10.1093/hmg/ddl456

  • Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M., Pemberton, Josephine M. and Pilkington, Jill G. (2007) Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). Journal of Parasitology, 37 1: 121-129. doi:10.1016/j.ijpara.2006.09.007

  • Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M. and Pemberton, Josephine M. (2006) Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries). Genetics, 173 3: 1521-1537. doi:10.1534/genetics.106.057141

Conference Publication

  • Kwok, J., Coupland, K., Mellick, G., Mather, K., Thalamuthu, A., Armstrong, N., Sachdev, P., Brodaty, H., Wright, M., Ames, D., Allen, M., Ertekin-Taner, N., McRae, A., Bennett, D., Jager, P. D., Kim, W., Halliday, G. and Dobson-Stone, C. (2015). Genome-wide association study identifies the SLC2A14 gene on chromosome 12P13 as a trans-acting locus for methylation of MAPT gene. In: Special Issue: 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, (113-114). 23-27 August 2015. doi:10.1111/jnc.13188

  • Thomas, Gethin P., Tseng, Hsu-Wen, Pettit, Allison, Glant, Tibor T., McRae, Allan and Brown, Matthew A. (2013). Endochondral Bone Formation and Advanced Enthesitis Are Key Features Of Proteoglycan Induced Spondylitis Mouse Model Of Ankylosing Spondylitis. In: Abstract Supplement 2013 Annual Meeting. 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego CA, United States, (S231-S231). 25-30 October 2013. doi:10.1002/art.38216

  • Medland, S. E., Nyholt, D. R., Painter, J. N., McEvoy, B. P., McRae, A. F., Montgomery, G. W. and Martin, N. G. (2010). Common variants in the Trichohyalin gene are associated with straight hair in Europeans genetics and genodermatoses. In: 6th World Congress for Hair Research, Cairns, QLD, Australia, (563-563). 16-19 June 2010. doi:10.1111/j.1600-0625.2010.01097.x

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Master Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision