The University of Queensland

Journal Article

• A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration

  San Gil, Rebecca, Pascovici, Dana, Venturato, Juliana, Brown-Wright, Heledd, Mehta, Prachi, Madrid San Martin, Lidia, Wu, Jemma, Luan, Wei, Chui, Yi Kit, Bademosi, Adekunle T., Swaminathan, Shilpa, Naidoo, Serey, Berning, Britt A., Wright, Amanda L., Keating, Sean S., Curtis, Maurice A., Faull, Richard L. M., Lee, John D., Ngo, Shyuan T., Lee, Albert, Morsch, Marco, Chung, Roger S., Scotter, Emma, Lisowski, Leszek, Mirzaei, Mehdi and Walker, Adam K. (2024). A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration. Nature Communications, 15 (1) 1508, 1508. doi: 10.1038/s41467-024-45646-9

• Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD

  Luan, Wei, Wright, Amanda L., Brown-Wright, Heledd, Le, Sheng, San Gil, Rebecca, Madrid San Martin, Lidia, Ling, Karen, Jafar-Nejad, Paymaan, Rigo, Frank and Walker, Adam K. (2023). Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD. Molecular Psychiatry, 28 (6), 2445-2461. doi: 10.1038/s41380-023-02036-9

• The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS

  Keerie, Amy, Brown-Wright, Heledd, Kirkland, Isaac, Grierson, Andrew, Alix, James J. P., Holscher, Christian and Mead, Richard J. (2021). The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS. Scientific Reports, 11 (1) 17027, 1-10. doi: 10.1038/s41598-021-96418-0

• Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

  White, Matthew A., Lin, Ziqiang, Kim, Eugene, Henstridge, Christopher M., Altamira, Emiliano Pena, Hunt, Camille K., Burchill, Ella, Callaghan, Isobel, Loreto, Andrea, Brown-Wright, Heledd, Mead, Richard, Simmons, Camilla, Cash, Diana, Coleman, Michael P. and Sreedharan, Jemeen (2019). Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss. Acta Neuropathologica Communications, 7 (1) 166, 1-16. doi: 10.1186/s40478-019-0800-9

• Case report of concurrent Fabry disease and amyotrophic lateral sclerosis supports a common pathway of pathogenesis

  Beer, Alexander M., Cooper-Knock, Johnathan, Fletcher, Sakina, Brown-Wright, Sian Heledd, Nandakumar, T. Pisharam and Shaw, Pamela J. (2016). Case report of concurrent Fabry disease and amyotrophic lateral sclerosis supports a common pathway of pathogenesis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17 (7-8), 614-616. doi: 10.3109/21678421.2016.1170150