Dr Sussan Ghassabian

ADME Scientist/Research Fellow

School of Biomedical Sciences
Faculty of Medicine
s.ghassabian@uq.edu.au
+61 7 334 65194

Overview

PharmD: University of Shaheed Beheshti

PhD: University of Sydney (2005-2009)

Postdoctoral Reserach Fellow: University of Sydney (2009-2010)

ADME Scientist/Research Fellow: Centre for Integrated Preclinical Drug Development, University of Queensland (2011- current)

Research Interests

  • Clinical Pharmacology
    In vivo Cytochrome P450 phenotyping in order to increase the safety of the pharmacotherapy
  • Analytical Chemistry
    Bioanalytical method development and validation using LC-MS/MS and HPLC
  • Drug Metabolism
    In vitro and in vivo metabolism of drugs by Cytochrome P450 enzymes
  • Drug Development
    Bioanalytical method development and validation for novel compounds and the study of their metabolism and pharmacokinetics in preclinical stage
  • Pharmacokinetics
    Determination of pharmacokinetic parameters of novel drugs

Qualifications

  • Doctor of Philosophy, The University of Sydney

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • (2015) Doctor Philosophy

View all Supervision

Available Projects

View all Available Projects

Publications

Book Chapter

  • Ghassabian, Sussan and Murray, Michael (2013). Simultaneous in vivo phenotyping of CYP enzymes. In Ian R. Phillips, Elizabeth A. Shepherd and Paul R. Ortiz de Montellano (Ed.), Cytochrome P450 protocols 3rd ed. (pp. 261-267) New York, NY, United States: Humana Press. doi:10.1007/978-1-62703-321-3_22

Journal Article

Conference Publication

  • Ghassabian, Sussan, Rethwan, Ahmad, Griffiths, Lyn and Smith, Maree (2014). Development and validation of an lc-ms/ms bioanalytical method for quantification of homocysteine (hcy) in samples of human serum. In: International Pharmaceutical Federation (FIP), Melbourme, Australia, (). 13-16 April 2014.

  • Shekar, K., Diab, S., McDonald, C., Fisquet, S., Dunster, K., Fung, L., Platts, D., Ghassabian, S., Barnett, A., Roberts, J., Smith, M. and Fraser, J. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation may cause therapeutic failure. In: Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Brisbane, QLD, Australia, (S235-S236). 16-19 August 2012. doi:10.1016/j.hlc.2012.05.581

  • Shekar, K., Mcdonald, C., Fisquet, S., Barnett, A., Ghassabian, S., Fung, L., Roberts, J., Smith, M. and Fraser, J. (2012). Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation may cause therapeutic failure. In: Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meetin, Brisbane, QLD, Australia, (S237-S238). 16-19 August 2012. doi:10.1016/j.hlc.2012.05.584

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

Completed Supervision

Possible Research Projects

Note for students: The possible research projects listed on this page may not be comprehensive or up to date. Always feel free to contact the staff for more information, and also with your own research ideas.