The University of Queensland

Estimation and partition of heritability in human populations using whole-genome analysis methods

Vinkhuyzen, Anna A.E., Wray, Naomi R., Yang, Jiang, Goddard, Michael E. and Visscher, Peter M. (2013) Estimation and partition of heritability in human populations using whole-genome analysis methods. Annual Review of Genetics, Review in Advance: 47 5: 93-113. doi:10.1146/annurev-genet-111212-133258

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion

Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012) Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Translational Psychiatry, 2 e102: . doi:10.1038/tp.2012.27

Nineteen and Up study (19Up): Understanding pathways to mental health disorders in young Australian twins

Couvy-Duchesne, Baptiste, O'Callaghan, Victoria, Parker, Richard, Mills, Natalie, Kirk, Katherine M., Scott, Jan, Vinkhuyzen, Anna., Hermens, Daniel F, Lind, Penelope A., Davenport, Tracey A, Burns, Jane M, Connell, Melissa, Zietsch, Brendan P., Scott, James, Wright, Margaret J., Medland, Sarah E, McGrath, John, Martin, Nicholas G., Hickie, Ian B. and Gillespie, Nathan A. (2018) Nineteen and Up study (19Up): Understanding pathways to mental health disorders in young Australian twins. BMJ open, 8 3: . doi:10.1136/bmjopen-2017-018959

Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals

Bouwman, Aniek C., Daetwyler, Hans D., Chamberlain, Amanda J., Ponce, Carla Hurtado, Sargolzaei, Mehdi, Schenkel, Flavio S., Sahana, Goutam, Govignon-Gion, Armelle, Boitard, Simon, Dolezal, Marlies, Pausch, Hubert, Brøndum, Rasmus F., Bowman, Phil J., Thomsen, Bo, Guldbrandtsen, Bernt, Lund, Mogens S., Servin, Bertrand, Garrick, Dorian J., Reecy, James, Vilkki, Johanna, Bagnato, Alessandro, Wang, Min, Hoff, Jesse L., Schnabel, Robert D., Taylor, Jeremy F., Vinkhuyzen, Anna A. E., Panitz, Frank, Bendixen, Christian, Holm, Lars-Erik, Gredler, Birgit, Hozé, Chris, Boussaha, Mekki, Sanchez, Marie-Pierre, Rocha, Dominique, Capitan, Aurelien, Tribout, Thierry, Barbat, Anne, Croiseau, Pascal, Drögemüller, Cord, Jagannathan, Vidhya, Vander Jagt, Christy, Crowley, John J., Bieber, Anna, Purfield, Deirdre C., Berry, Donagh P., Emmerling, Reiner, Götz, Kay-Uwe, Frischknecht, Mirjam, Russ, Ingolf, Sölkner, Johann, Van Tassell, Curtis P., Fries, Ruedi, Stothard, Paul, Veerkamp, Roel F., Boichard, Didier, Goddard, Mike E. and Hayes, Ben J. (2018) Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals. Nature Genetics, 50 . doi:10.1038/s41588-018-0056-5

Investigating the relationship between iron and depression

Mills, Natalie T., Maier, Robert, Whitfield, John B., Wright, Margaret J., Colodro-Conde, Lucia, Byrne, Enda M., Scott, James G., Byrne, Gerard J., Hansell, Narelle K., Vinkhuyzen, Anna A. E., CouvyDuchesne, Baptiste, Montgomery, Grant W., Henders, Anjali K., Martin, Nicholas G., Wray, Naomi R. and Benyamin, Beben (2017) Investigating the relationship between iron and depression. Journal of Psychiatric Research, 94 148-155. doi:10.1016/j.jpsychires.2017.07.006

Gestational vitamin D deficiency and autism spectrum disorder

Vinkhuyzen, Anna A. E., Eyles, Darryl W., Burne, Thomas H. J., Blanken, Laura M. E., Kruithof, Claudia J., Verhulst, Frank, White, Tonya, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2017) Gestational vitamin D deficiency and autism spectrum disorder. Bjpsych Open, 3 2: 85-90. doi:10.1192/bjpo.bp.116.004077

Genetic evidence of assortative mating in humans

Robinson, Matthew R., Kleinman, Aaron, Graff, Mariaelisa, Vinkhuyzen, Anna A. E., Couper, David, Miller, Michael B., Peyrot, Wouter J., Abdellaoui, Abdel, Zietsch, Brendan P., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, The LifeLines Cohort Study, Genetic Investigation of Anthropometric Traits (GIANT) consortium, Medland, Sarah E., Martin, Nicholas G., Magnusson, Patrik K. E., Iacono, William G., McGue, Matt, North, Kari E., Yang, Jian and Visscher, Peter M. (2017) Genetic evidence of assortative mating in humans. Nature Human Behaviour, 1 1: . doi:10.1038/s41562-016-0016

Gestational vitamin D deficiency and autism-related traits: the Generation R Study

Vinkhuyzen, A. A. E., Eyles, D. W., Burne, T. H. J., Blanken, L. M. E., Kruithof, C. J., Verhulst, F., Jaddoe, V. W., Tiemeier, H. and McGrath, J. J. (2016) Gestational vitamin D deficiency and autism-related traits: the Generation R Study. Molecular Psychiatry, . doi:10.1038/mp.2016.213

Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits

Bakshi, Andrew, Zhu, Zhihong, Vinkhuyzen, Anna A. E., Hill, W. David, Mcrae, Allan F., Visscher, Peter M. and Yang, Jian (2016) Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. Scientific Reports, 6 . doi:10.1038/srep32894

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Okbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A., Liu, Tian, Matteson, Lindsay, Mihailov, Evelin, Miller, Michael B., Minica, Camelia C., Nolte, Ilja M., Mook-Kanamori, Dennis, van der Most, Peter J., Oldmeadow, Christopher, Qian, Yong, Raitakari, Olli, Rawal, Rajesh, Realo, Anu, Rueedi, Rico, Schmidt, Borge, Smith, Albert V., Stergiakouli, Evie, Tanaka, Toshiko, Taylor, Kent, Wedenoja, Juho, Wellmann, Juergen, Westra, Harm-Jan, Willems, Sara M., Zhao, Wei, Amin, Najaf, Bakshi, Andrew, Boyle, Patricia A., Cherney, Samantha, Cox, Simon R., Davies, Gail, Davis, Oliver S. P., Ding, Jun, Direk, Nese, Eibich, Peter, Emeny, Rebecca T., Fatemifar, Ghazaleh, Faul, Jessica D., Ferrucci, Luigi, Forstner, Andreas, Gieger, Christian, Gupta, Richa, Harris, Tamara B., Harris, Juliette M., Holliday, Elizabeth G., Hottenga, Jouke-Jan, De Jager, Philip L., Kaakinen, Marika A., Kajantie, Eero, Karhunen, Ville, Kolcic, Ivana, Kumari, Meena, Launer, Lenore J., Franke, Lude, Li-Gao, Ruifang, Koini, Marisa, Loukola, Anu, Marques-Vidal, Pedro, Montgomery, Grant W., Mosing, Miriam A., Paternoster, Lavinia, Pattie, Alison, Petrovic, Katja E., Pulkki-Raback, Laura, Quaye, Lydia, Raikkonen, Katri, Rudan, Igor, Scott, Rodney J., Smith, Jennifer A., Sutin, Angelina R., Trzaskowski, Maciej, Vinkhuyzen, Anna E., Yu, Lei, Zabaneh, Delilah, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Boomsma, Dorret I., Snieder, Harold, Chang, Shun-Chiao, Cucca, Francesco, Deary, Ian J., van Duijn, Cornelia M., Eriksson, Johan G., Bultmann, Ute, de Geus, Eco J. C., Groenen, Patrick J. F., Gudnason, Vilmundur, Hansen, Torben, Hartman, Catharine A., Haworth, Claire M. A., Hayward, Caroline, Heath, Andrew C., Hinds, David A., Hypponen, Elina, Iacono, William G., Jarvelin, Marjo-Riitta, Jockel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Keltikangas-Jarvinen, Liisa, Kraft, Peter, Kubzansky, Laura D., Lehtimaki, Terho, Magnusson, Patrik K. E., Martin, Nicholas G., Mcgue, Matt, Metspalu, Andres, Mills, Melinda, de Mutsert, Renee, Oldehinkel, Albertine J., Pasterkamp, Gerard, Pedersen, Nancy L., Plomin, Robert, Polasek, Ozren, Power, Christine, Rich, Stephen S., Rosendaal, Frits R., den Ruijter, Hester M., Schlessinger, David, Schmidt, Helena, Svento, Rauli, Schmidt, Reinhold, Alizadeh, Behrooz Z., Sorensen, Thorkild I. A., Spector, Tim D., Steptoe, Andrew, Terracciano, Antonio, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Uitterlinden, Andre G., Vollenweider, Peter, Wagner, Gert G., Weir, David R., Yang, Jian, Conley, Dalton C., Smith, George Davey, Hofman, Albert, Johannesson, Magnus, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Pickrell, Joseph K., Esko, Tonu, Krueger, Robert F., Beauchamp, Jonathan P., Koellinger, Philipp D., Benjamin, Daniel J., Bartels, Meike and Cesarini, David (2016) Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics, 48 6: 624-633. doi:10.1038/ng.3552

Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes

Miliku, Kozeta, Vinkhuyzen, Anna, Blanken, Laura M. E., McGrath, John J., Eyles, Darryl W., Burne, Thomas H., Hofman, Albert, Tiemeier, Henning, Steegers, Eric A. P., Gaillard, Romy and Jaddoe, Vincent W. V. (2016) Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes. American Journal of Clinical Nutrition, 103 6: 1514-1522. doi:10.3945/ajcn.115.123752

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, Aysu, Beauchamp, Jonathan P., Fontana, Mark Alan, Lee, James J., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, van der Lee, Sven J., de Leeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., van der Most, Peter J., Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J., Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Brge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., St Pourcain, Beate, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bonnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldorsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Joshi, Peter K., Jugessur, Astanand, Kaakinen, Marika A., Kahonen, Mika, Kanoni, Stavroula, Keltigangas-Jarvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J., Lebreton, Mael P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, Anu, Madden, Pamela A., Magi, Reedik, Maki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Meddens, Gerardus A., McMahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W., Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Raikkonen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J. A., Venturini, Cristina, Vinkhuyzen, Anna A. E., Volker, Uwe, Volzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I., Borecki, Ingrid B., Bultmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., van Duijn, Cornelia M., Eriksson, Johan G., Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jorgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, van der Harst, Pim, Hayward, Caroline, Hinds, David A., Hoffmann, Wolfgang, Hyppnen, Elina, Iacono, William G., Jacobsson, Bo, Jarvelin, Marjo-Riitta, Jockel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehtimaki, Terho, Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., McGue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W. J. H., Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sorensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Tung, Joyce Y., Uitterlinden, Andre G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Yang, Jian, Johannesson, Magnus, Visscher, Peter M., Esko, Tonu, Koellinger, Philipp D., Cesarini, David and Benjamin, Daniel J. (2016) Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 7604: 539-542. doi:10.1038/nature17671

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Yingchang, Day, Felix R., Gustafsson, Stefan, Buchkovich, Martin L., Na, Jianbo, Bataille, Veronique, Cousminer, Diana L., Dastani, Zari, Drong, Alexander W., Esko, Tonu, Evans, David M., Falchi, Mario, Feitosa, Mary F., Ferreira, Teresa, Hedman, Asa K., Haring, Robin, Hysi, Pirro G., Iles, Mark M., Justice, Anne E., Kanoni, Stavroula, Lagou, Vasiliki, Li, Rui, Li, Xin, Locke, Adam, Lu, Chen, Magi, Reedik, Perry, John R. B., Pers, Tune H., Qi, Qibin, Sanna, Marianna, Schmidt, Ellen M., Scott, William R., Shungin, Dmitry, Teumer, Alexander, Vinkhuyzen, Anna A. E., Walker, Ryan W., Westra, Harm-Jan, Zhang, Mingfeng, Zhang, Weihua, Zhao, Jing Hua, Zhu, Zhihong, Afzal, Uzma, Ahluwalia, Tarunveer Singh, Bakker, Stephan J. L., Bellis, Claire, Bonnefond, Amelie, Borodulin, Katja, Buchman, Aron S., Cederholm, Tommy, Choh, Audrey C., Choi, Hyung Jin, Curran, Joanne E., de Groot, Lisette C. P. G. M., De Jager, Philip L., Dhonukshe-Rutten, Rosalie A. M., Enneman, Anke W., Eury, Elodie, Evans, Daniel S., Forsen, Tom, Friedrich, Nele, Fumeron, Frederic, Garcia, Melissa E., Gartner, Simone, Han, Bok-Ghee, Havulinna, Aki S., Hayward, Caroline, Hernandez, Dena, Hillege, Hans, Ittermann, Till, Kent, Jack W., Kolcic, Ivana, Laatikainen, Tiina, Lahti, Jari, Leach, Irene Mateo, Lee, Christine G., Lee, Jong-Young, Liu, Tian, Liu, Youfang, Lobbens, Stephane, Loh, Marie, Lyytikainen, Leo-Pekka, Medina-Gomez, Carolina, Michaelsson, Karl, Nalls, Mike A., Nielson, Carrie M., Oozageer, Laticia, Pascoe, Laura, Paternoster, Lavinia, Polasek, Ozren, Ripatti, Samuli, Sarzynski, Mark A., Shin, Chan Soo, Narancic, Nina Smolej, Spira, Dominik, Srikanth, Priya, Steinhagen-Thiessen, Elisabeth, Sung, Yun Ju, Swart, Karin M. A., Taittonen, Leena, Tanaka, Toshiko, Tikkanen, Emmi, van der Velde, Nathalie, van Schoor, Natasja M., Verweij, Niek, Wright, Alan F., Yu, Lei, Zmuda, Joseph M., Eklund, Niina, Forrester, Terrence, Grarup, Niels, Jackson, Anne U., Kristiansson, Kati, Kuulasmaa, Teemu, Kuusisto, Johanna, Lichtner, Peter, Luan, Jian'an, Mahajan, Anubha, Mannisto, Satu, Palmer, Cameron D., Ried, Janina S., Scott, Robert A., Stancakova, Alena, Wagner, Peter J., Demirkan, Ayse, Doring, Angela, Gudnason, Vilmundur, Kiel, Douglas P., Kuhnel, Brigitte, Mangino, Massimo, Mcknight, Barbara, Menni, Cristina, O'Connell, Jeffrey R., Oostra, Ben A., Shuldiner, Alan R., Song, Kijoung, Vandenput, Liesbeth, van Duijn, Cornelia M., Vollenweider, Peter, White, Charles C., Boehnke, Michael, Boettcher, Yvonne, Cooper, Richard S., Forouhi, Nita G., Gieger, Christian, Grallert, Harald, Hingorani, Aroon, Jorgensen, Torben, Jousilahti, Pekka, Kivimaki, Mika, Kumari, Meena, Laakso, Markku, Langenberg, Claudia, Linneberg, Allan, Luke, Amy, Mckenzie, Colin A., Palotie, Aarno, Pedersen, Oluf, Peters, Annette, Strauch, Konstantin, Tayo, Bamidele O., Wareham, Nicholas J., Bennett, David A., Bertram, Lars, Blangero, John, Bluher, Matthias, Bouchard, Claude, Campbell, Harry, Cho, Nam H., Cummings, Steven R., Czerwinski, Stefan A., Demuth, Ilja, Eckardt, Rahel, Eriksson, Johan G., Ferrucci, Luigi, Franco, Oscar H., Froguel, Philippe, Gansevoort, Ron T., Hansen, Torben, Harris, Tamara B., Hastie, Nicholas, Heliovaara, Markku, Hofman, Albert, Jordan, Joanne M., Jula, Antti, Kahonen, Mika, Kajantie, Eero, Knekt, Paul B., Koskinen, Seppo, Kovacs, Peter, Lehtimaki, Terho, Lind, Lars, Liu, Yongmei, Orwoll, Eric S., Osmond, Clive, Perola, Markus, Perusse, Louis, Raitakari, Olli T., Rankinen, Tuomo, Rao, D. C., Rice, Treva K., Rivadeneira, Fernando, Rudan, Igor, Salomaa, Veikko, Sorensen, Thorkild I. A., Stumvoll, Michael, Tonjes, Anke, Towne, Bradford, Tranah, Gregory J., Tremblay, Angelo, Uitterlinden, Andre G., van der Harst, Pim, Vartiainen, Erkki, Viikari, Jorma S., Vitart, Veronique, Vohl, Marie-Claude, Volzke, Henry, Walker, Mark, Wallaschofski, Henri, Wild, Sarah, Wilson, James F., Yengo, Loic, Bishop, D. Timothy, Borecki, Ingrid B., Chambers, John C., Cupples, L. Adrienne, Dehghan, Abbas, Deloukas, Panos, Fatemifar, Ghazaleh, Fox, Caroline, Furey, Terrence S., Franke, Lude, Han, Jiali, Hunter, David J., Karjalainen, Juha, Karpe, Fredrik, Kaplan, Robert C., Kooner, Jaspal S., McCarthy, Mark I., Murabito, Joanne M., Morris, Andrew P., Bishop, Julia A. N., North, Kari E., Ohlsson, Claes, Ong, Ken K., Prokopenko, Inga, Richards, J. Brent, Schadt, Eric E., Spector, Tim D., Widen, Elisabeth, Willer, Cristen J., Yang, Jian, Ingelsson, Erik, Mohlke, Karen L., Hirschhorn, Joel N., Pospisilik, John Andrew, Zillikens, M. Carola, Lindgren, Cecilia, Kilpelainen, Tuomas Oskari and Loos, Ruth J. F. (2016) New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications, 7 . doi:10.1038/ncomms10495

Genes influence the amplitude and timing of brain hemodynamic responses

Shan, Zuyao Y., Vinkhuyzen, Anna A. E., Thompson, Paul M., McMahon, Katie L., Blokland, Gabriella A.M., de Zubicaray, Greig I., Calhoun, Vince, Martin, Nicholas G., Visscher, Peter M., Wright, Margaret J. and Reutens, David C. (2016) Genes influence the amplitude and timing of brain hemodynamic responses. NeuroImage, 124 Part A: 663-671. doi:10.1016/j.neuroimage.2015.09.016

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, Study, Lifelines Cohort, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik and Visscher, Peter M. (2015) Genome-wide genetic homogeneity between sexes and populations for human height and body mass index. Human Molecular Genetics, 24 25: 7445-7449. doi:10.1093/hmg/ddv443

Population genetic differentiation of height and body mass index across Europe

Robinson, Matthew R., Hemani, Gibran, Medina-Gomez, Carolina, Mezzavilla, Massimo, Esko, Tonu, Shakhbazov, Konstantin, Powell, Joseph E., Vinkhuyzen, Anna, Berndt, Sonja I., Gustafsson, Stefan, Justice, Anne E., Kahali, Bratati, Locke, Adam E., Pers, Tune H., Vedantam, Sailaja, Wood, Andrew R., van Rheenen, Wouter, Andreassen, Ole A., Gasparini, Paolo, Metspalu, Andres, van den Berg, Leonard H., Veldink, Jan H., Rivadeneira, Fernando, Werge, Thomas M., Abecasis, Goncalo R., Boomsma, Dorret I., Chasman, Daniel I., de Geus, Eco J. C., Frayling, Timothy M., Hirschhorn, Joel N., Hottenga, Jouke Jan, Ingelsson, Erik, Loos, Ruth J. F., Magnusson, Patrik K. E., Martin, Nicholas G., Montgomery, Grant W., North, Kari E., Pedersen, Nancy L., Spector, Timothy D., Speliotes, Elizabeth K., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2015) Population genetic differentiation of height and body mass index across Europe. Nature Genetics, 47 11: 1357-1361. doi:10.1038/ng.3401

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Lee, Sang Hong, Robinson, Matthew R., Perry, John R. B., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, The LifeLines Cohort Study, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik, Soranzo, Nicole, Keller, Matthew C., Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2015) Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nature Genetics, 47 10: 1114-1120. doi:10.1038/ng.3390

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

Zhu, Zhihong, Bakshi, Andrew, Vinkhuyzen, Anna A. E., Hemani, Gibran, Lee, Sang Hong, Nolte, Ilja M., vanVliet-Ostaptchouk, Jana V., Snieder, Harold, Esko, Tonu, Milani, Lili, Magi, Reedik, Metspalu, Andres, Hill, William G., Weir, Bruce S., Goddard, Michael E., Visscher, Peter M. and Yang, Jian (2015) Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits. American Journal of Human Genetics, 96 3: 377-385. doi:10.1016/j.ajhg.2015.01.001

Genetic studies of body mass index yield new insights for obesity biology

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Heritability of Transforming Growth Factor-β1 and Tumor Necrosis Factor-Receptor Type 1 Expression and Vitamin D Levels in Healthy Adolescent Twins

Mills, Natalie T., Wright, Margaret J., Henders, Anjali K., Eyles, Darryl W., Baune, Bernhard T., McGrath, John J., Byrne, Edna M., Hansell, Narelle K., Birosova, Eva, Scott, James G., Martin, Nicholas G., Montgomery, Grant W., Wray, Naomi R. and Vinkhuyzen, Anna A. E. (2015) Heritability of Transforming Growth Factor-β1 and Tumor Necrosis Factor-Receptor Type 1 Expression and Vitamin D Levels in Healthy Adolescent Twins. Twin Research and Human Genetics, 18 1: 28-35. doi:10.1017/thg.2014.70

Genetic and environmental contributions to the inverse association between specific autistic traits and experience seeking in adults

Romero-Martinez, Angel, Moya-Albiol, Luis, Vinkhuyzen, Anna A. E. and Polderman, Tinca J. C. (2015) Genetic and environmental contributions to the inverse association between specific autistic traits and experience seeking in adults. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 171 8: 1190-1197. doi:10.1002/ajmg.b.32352

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

Lee, S. Hong, Byrne, Enda M., Hultman, Christina M., Kahler, Anna, Vinkhuyzen, Anna A. E., Ripke, Stephan, Andreassen, Ole A., Frisell, Thomas, Gusev, Alexander, Hu, Xinli, Karlsson, Robert, Mantzioris, Vasilis X., McGrath, John J., Mehta, Divya, Stahl, Eli A., Zhao, Qiongyi, Kendler, Kenneth S., Sullivan, Patrick F., Price, Alkes L., O'Donovan, Michael, Okada, Yukinori, Mowry, Bryan J., Raychaudhuri, Soumya, Wray, Naomi R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Rheumatoid Arthritis Consortium International and Visscher, Peter M . (2015) New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology, 44 5: 1-16. doi:10.1093/ije/dyv136

Prevalence and predictors of vitamin D deficiency based on maternal mid-gestation and neonatal cord bloods: the Generation R Study

Vinkhuyzen, Anna A.E., Eyles, Darryl W., Burne, Thomas H., Blanken, Laura M.E., Kruithof, Claudia J., Verhulst, Frank, Jaddoe, Vincent W., Tiemeier, Henning and McGrath, John J. (2015) Prevalence and predictors of vitamin D deficiency based on maternal mid-gestation and neonatal cord bloods: the Generation R Study. Journal of Steroid Biochemistry And Molecular Biology, 164 161-167. doi:10.1016/j.jsbmb.2015.09.018

Replicability and robustness of genome-wide-association studies for behavioral traits

Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tonu, Medland, Sarah E., Vinkhuyzen, Anna A. E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T., Domingue, Benjamin W., Hinds, David A., Johannesson, Magnus, Kiefer, Amy K., Laibson, David, Magnusson, Patrik K. E., Mountain, Joanna L., Oskarsson, Sven, Rostapshova, Olga, Teumer, Alexander, Tung, Joyce Y., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David and Koellinger, Philipp D. (2014) Replicability and robustness of genome-wide-association studies for behavioral traits. Psychological Science, 25 11: 1975-1986. doi:10.1177/0956797614545132

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood, Andrew R., Esko, Tonu, Yang, Jian, Vedantam, Sailaja, Pers, Tune H., Gustafsson, Stefan, Chu, Audrey Y., Estrada, Karol, Luan, Jian'an, Kutalik, Zoltan, Amin, Najaf, Buchkovich, Martin L., Croteau-Chonka, Damien C., Day, Felix R., Duan, Yanan, Fall, Tove, Fehrmann, Rudolf, Ferreira, Teresa, Jackson, Anne U., Karjalainen, Juha, Lo, Ken Sin, Locke, Adam E., Magi, Reedik, Mihailov, Evelin, Porcu, Evelin, Randall, Joshua C., Scherag, Andre, Vinkhuyzen, Anne A. 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Novel directions for G × E analysis in psychiatry

Vinkhuyzen, A. A. E. and Wray, N. R. (2014) Novel directions for G × E analysis in psychiatry. Epidemiology and Psychiatric Sciences, 24 1: 12-19. doi:10.1017/S2045796014000584

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

Rietveld, Cornelius A., Esko, Tonu, Davies, Gail, Pers, Tune H., Turley, Patrick, Benyamin, Beben, Chabris, Christopher F., Emilsson, Valur, Johnson, Andrew D., Lee, James J., De Leeuw, Christiaan, Marioni, Riccardo E., Medland, Sarah E., Miller, Michael B., Rostapshova, Olga, Van Der Lee, Sven J., Vinkhuyzen, Anna A. E., Amin, Najaf, Conley, Dalton, Derringer, Jaime, Van Duijn, Cornelia M., Fehrmann, Rudolf, Franke, Lude, Glaeser, Edward L., Hansell, Narelle K., Hayward, Caroline, Iacono, William G., Ibrahim-Verbaas, Carla, Jaddoe, Vincent, Karjalainen, Juha, Laibson, David, Lichtenstein, Paul, Liewald, David C., Magnusson, Patrik K. E., Martin, Nicholas G., McGue, Matt, McMahon, George, Pedersen, Nancy L., Pinker, Steven, Porteous, David J., Posthuma, Danielle, Rivadeneira, Fernando, Smithk, Blair H., Starr, John M., Tiemeier, Henning, Timpsonm, Nicholas J., Trzaskowskin, Maciej, Uitterlinden, Andre G., Verhulst, Frank C., Ward, Mary E., Wright, Margaret J., Smith, George Davey, Deary, Ian J., Johannesson, Magnus, Plomin, Robert, Visscher, Peter M., Benjamin, Daniel J., Cesarini, David and Koellinger, Philipp D. (2014) Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proceedings of the National Academy of Sciences of the United States of America, 111 38: 13790-13794. doi:10.1073/pnas.1404623111

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method (vol 111, pg 13790, 2014)

Rietveld, Cornelius A., Esko, Tonu, Davies, Gail, Pers, Tune H., Turley, Patrick, Benyamin, Beben, Chabris, Christopher F., Emilsson, Valur, Johnson, Andrew D., Lee, James J., de Leeuw, Christiaan, Marioni, Riccardo E., Medland, Sarah E., Miller, Michael B., Rostapshova, Olga, van der Lee, Sven J., Vinkhuyzen, Anna A. E., Amin, Najaf, Conley, Dalton, Derringer, Jaime, van Duijn, Cornelia M., Fehrmann, Rudolf, Franke, Lude, Glaeser, Edward L., Hansell, Narelle K., Hayward, Caroline, Iacono, William G., Ibrahim-Verbaas, Carla, Jaddoe, Vincent, Karjalainen, Juha, Laibson, David, Lichtenstein, Paul, Liewald, David C., Magnusson, Patrik K. E., Martin, Nicholas G., McGue, Matt, McMahon, George, Pedersen, Nancy L., Pinker, Steven, Porteous, David J., Posthuma, Danielle, Rivadeneira, Fernando, Smith, Blair H., Starr, John M., Tiemeier, Henning, Timpson, Nicholas J., Trzaskowski, Maciej, Uitterlinden, Andre G., Verhulst, Frank C., Ward, Mary E., Wright, Margaret J., Smith, George Davey, Deary, Ian J., Johannesson, Magnus, Plomin, Robert, Visscher, PeterM., Benjamin, Daniel J., Cesarini, David and Koellinger, Philipp D. (2014) Common genetic variants associated with cognitive performance identified using the proxy-phenotype method (vol 111, pg 13790, 2014). Proceedings of the National Academy of Sciences of the United States of America, 112 4: E380-E380. doi:10.1073/pnas.1424631112

Genetic influences are virtually absent for trust

Van Lange, Paul A. M., Vinkhuyzen, Anna A. E. and Posthuma, Danielle (2014) Genetic influences are virtually absent for trust. PLoS One, 9 4: e93880.1-e93880.8. doi:10.1371/journal.pone.0093880

Modeling of the hemodynamic responses in block design fMRI studies

Shan, Zuyao Y., Wright, Margaret J., Thompson, Paul M., McMahon, Katie L., Blokland, Gabriella G. A. M., de Zubicaray, Greig I., Martin, Nicholas G., Vinkhuyzen, Anna A. E. and Reutens, David C. (2014) Modeling of the hemodynamic responses in block design fMRI studies. Journal of Cerebral Blood Flow and Metabolism, 34 2: 316-324. doi:10.1038/jcbfm.2013.200

Research Review: Polygenic methods and their application to psychiatric traits

Wray, Naomi R., Lee, Sang Hong, Mehta, Divya, Vinkhuyzen, Anna A. E., Dudbridge, Frank and Middeldorp, Christel M. (2014) Research Review: Polygenic methods and their application to psychiatric traits. Journal of Child Psychology and Psychiatry, 55 10: 1068-1087. doi:10.1111/jcpp.12295

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E. and Yang, Jian (2014) Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples. PLoS Genetics, 10 4: e1004269.1-e1004269.10. doi:10.1371/journal.pgen.1004269

Estimation and partition of heritability in human populations using whole-genome analysis methods

Vinkhuyzen, Anna A.E., Wray, Naomi R., Yang, Jiang, Goddard, Michael E. and Visscher, Peter M. (2013) Estimation and partition of heritability in human populations using whole-genome analysis methods. Annual Review of Genetics, Review in Advance: 47 5: 93-113. doi:10.1146/annurev-genet-111212-133258

Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs

Hemani, Gibran, Yang, Jian, Vinkhuyzen, Anna, Powell, Joseph E., Willemsen, Gonneke, Hottenga, Jouke-Jan, Abdellaoui, Abdel, Mangino, Massimo, Valdes, Ana M., Medland, Sarah E., Madden, Pamela A., Heath, Andrew C., Henders, Anjali K., Nyholt, Dale R., de Geus, Eco J. C., Magnusson, Patrik K. E., Ingelsson, Erik, Montgomery, Grant W., Spector, Timothy D., Boomsma, Dorret I., Pedersen, Nancy L., Martin, Nicholas G. and Visscher, Peter M. (2013) Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs. American Journal of Human Genetics, 93 5: 865-875. doi:10.1016/j.ajhg.2013.10.005

Attentional switching forms a genetic link between attention problems and autistic traits in adults

Polderman, T. J. C., Hoekstra, R. A., Vinkhuyzen, A. A. E., Sullivan, P. F., van der Sluis, S. and Posthuma, D. (2013) Attentional switching forms a genetic link between attention problems and autistic traits in adults. Psychological Medicine, 43 9: 1985-1996. doi:10.1017/S0033291712002863

Genome-wide association uncovers shared genetic effects among personality traits and mood states

Luciano, Michelle, Huffman, Jennifer E., Arias-Vasquez, Alejandro, Vinkhuyzen, Anna A. E., Middeldorp, Christel M., Giegling, Ina, Payton, Antony, Davies, Gail, Zgaga, Lina, Janzing, Joost, Ke, Xiayi, Galesloot, Tessel, Hartmann, Annette M., Ollier, William, Tenesa, Albert, Hayward, Caroline, Verhagen, Maaike, Montgomery, Grant W., Hottenga, Jouke-Jan, Konte, Bettina, Starr, John M., Vitart, Veronique, Vos, Pieter E., Madden, Pamela A. F., Willemsen, Gonneke, Konnerth, Heike, Horan, Michael A., Porteous, David J., Campbell, Harry, Vermeulen, Sita H., Heath, Andrew C., Wright, Alan, Polasek, Ozren, Kovacevic, Sanja B., Hastie, Nicholas D., Franke, Barbara, Boomsma, Dorret I., Martin, Nicholas G., Rujescu, Dan, Wilson, James F., Buitelaar, Jan, Pendleton, Neil, Rudan, Igor and Deary, Ian J. (2012) Genome-wide association uncovers shared genetic effects among personality traits and mood states. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B 6: 684-695. doi:10.1002/ajmg.b.32072

The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation

Verweij, Karin J. H., Vinkhuyzen, Anna A. E., Benyamin, Beben, Lynskey, Michael T., Quaye, Lydia, Agrawal, Arpana, Gordon, Scott D., Montgomery, Grant W., Madden, Pamela A. F., Heath, Andrew C., Spector, Andrew C., Martin, Nicholas G. and Medland, Sarah E. (2012) The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation. Addiction Biology, 18 5: 846-850. doi:10.1111/j.1369-1600.2012.00478.x

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012)

Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012) Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012). Translational Psychiatry, 2 . doi:10.1038/tp.2012.49

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion

Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012) Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Translational Psychiatry, 2 e102: . doi:10.1038/tp.2012.27

Interaction between experience seeking and genetic and environmental influences on general cognitive ability

Vinkhuyzen, Anna A. E., van der Sluis, Sophie and Posthuma, Danielle (2012) Interaction between experience seeking and genetic and environmental influences on general cognitive ability. Twin Research and Human Genetics, 15 1: 87-96. doi:10.1375/twin.15.1.87

Identification of tag haplotypes for 5HTTLPR for different genome-wide SNP platforms

Vinkhuyzen, A. A. E., Dumenil, T., Ryan, L., Gordon, S. D., Henders, A. K., Madden, P. A. F., Heath, A. C., Montgomery, G. W., Martin, N. G. and Wray, N. R. (2011) Identification of tag haplotypes for 5HTTLPR for different genome-wide SNP platforms. Molecular Psychiatry, 16 11: 1073-1075. doi:10.1038/mp.2011.68

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

Vinkhuyzen, Anna, John, Sujit, Periyasamy, Sathish, Wray, Naomi, Thara, Rangaswamy and Mowry, Bryan (2017). Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans. In: 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, (S341-S341). 16-20 October 2015.

Phenotypic and genetic association between attention problems and autistic traits in adults is mainly mediated by attentional switching ability

Polderman, Tinca, Hoekstra, Rosa, Vinkhuyzen, Anna, van der Sluis, Sophie and Posthuma, Danielle (2012). Phenotypic and genetic association between attention problems and autistic traits in adults is mainly mediated by attentional switching ability. In: Behavior Genetics Association 42nd Annual Meeting Abstracts. 42nd Annual Meeting of the Behavior Genetics Association, Edinburgh Scotland, (961-961). 22-25 June 2012.