I am a basic science researcher with training in cell biology, genetics and research translation. My research investigates the female reproductive system by focusing on the contribution of individual cells. I aim to understand the influence of genetic architecture, differentiation and maturation on these individual cells and how this contributes to changes in the microenvironment that can contribute to disease initiation and progression.
After the completion of my PhD in 2008 at the University of Queensland, I undertook post-doctoral studies at the University of Bern, Department of Biomedical Research (DBMR), focusing on endometriosis, ovarian and endometrial cancer. I curated patient samples from clinical research trials to investigate inflammatory and metabolic components of reproductive tissue and disease and began developing patient-derived models of the endometrium. I established a relationship between endometriosis lesions, nerves and pain and how this interaction was mediated by inflammation. I further developed patient-derived in vitro models to understand the interaction between inflammation and hormonal response of endometriotic lesions and how this could be utilized to target current and novel treatments. On returning to Australia in 2016 I joined the Genomics of Reproductive Disorders laboratory to integrate genetic background into patient-derived in vitro models. I established the Endometriosis Research Queensland Study (ERQS) in collaboration with the Royal Brisbane and Women’s Hospital (RBWH) and extended in vitro models into complex multi-cellular assembloids (combinations of organoids and surrounding stromal cells).
Marla, Sushma, Mortlock, Sally, Heinosalo, Taija, Poutanen, Matti, Montgomery, Grant W. and McKinnon, Brett David (2023). Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expression. BMC Medicine, 21 (1) 460, 460. doi: 10.1186/s12916-023-03166-1
Journal Article: Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis
Marla, Sushma, Mortlock, Sally, Yoon, Sohye, Crawford, Joanna, Andersen, Stacey, Mueller, Michael D., McKinnon, Brett, Nguyen, Quan and Montgomery, Grant W. (2023). Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis. Cells, 12 (13) 1736, 1-22. doi: 10.3390/cells12131736
Journal Article: New concepts on the etiology of endometriosis
Cousins, Fiona L., McKinnon, Brett D., Mortlock, Sally, Fitzgerald, Harriet C., Zhang, Chenyu, Montgomery, Grant W. and Gargett, Caroline E. (2023). New concepts on the etiology of endometriosis. Journal of Obstetrics and Gynaecology Research, 49 (4), 1090-1105. doi: 10.1111/jog.15549
Identifying endometriosis risk and disease variability by mapping endometrial stem cell maturation
(2023–2025) NHMRC IDEAS Grants
Generation of patient-derived micro-organoid spheres for precision medicine in endometriosis
(2023–2024) Metro North Hospital and Health Service
Environmental Risk Factors for Endometriosis
(2022–2023) Endometriosis Australia Ltd
Spatial resolved analysis of endometrial tissue
Master Philosophy
Development of molecular techniques for endometriosis sub-typing and diagnosis
Doctor Philosophy
Regulation of the endocannabinoid system in the endometrium across menstrual cycle and implications in endometriosis
Doctor Philosophy
Marla, Sushma, Mortlock, Sally, Heinosalo, Taija, Poutanen, Matti, Montgomery, Grant W. and McKinnon, Brett David (2023). Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expression. BMC Medicine, 21 (1) 460, 460. doi: 10.1186/s12916-023-03166-1
Marla, Sushma, Mortlock, Sally, Yoon, Sohye, Crawford, Joanna, Andersen, Stacey, Mueller, Michael D., McKinnon, Brett, Nguyen, Quan and Montgomery, Grant W. (2023). Global analysis of transcription start sites and enhancers in endometrial stromal cells and differences associated with endometriosis. Cells, 12 (13) 1736, 1-22. doi: 10.3390/cells12131736
New concepts on the etiology of endometriosis
Cousins, Fiona L., McKinnon, Brett D., Mortlock, Sally, Fitzgerald, Harriet C., Zhang, Chenyu, Montgomery, Grant W. and Gargett, Caroline E. (2023). New concepts on the etiology of endometriosis. Journal of Obstetrics and Gynaecology Research, 49 (4), 1090-1105. doi: 10.1111/jog.15549
Tanaka, Keisuke, Gilroy, Deborah, Subramaniam, Sugarniya, Lakshmi, Preethi, Bhadravathi Lokeshappa, Madhura, Wallace, Leanne M., Atluri, Sharat, Schmidt, Bart, Ganter, Peter, Baartz, David, Smith, Matthew, Mortlock, Sally, Henders, Anjali, Khalil, Akram, Montgomery, Grant, McKinnon, Brett and Amoako, Akwasi (2022). Protocol for the Endometriosis Research Queensland Study (ERQS): an integrated cohort study approach to improve diagnosis and stratify treatment. BMJ Open, 12 (10) e064073, 1-10. doi: 10.1136/bmjopen-2022-064073
Computer-aided histopathological characterisation of endometriosis lesions
McKinnon, Brett D., Nirgianakis, Konstantinos, Ma, Lijuan, Wotzkow, Carlos Alvarez, Steiner, Selina, Blank, Fabian and Mueller, Michael D. (2022). Computer-aided histopathological characterisation of endometriosis lesions. Journal of Personalized Medicine, 12 (9) 1519, 1-13. doi: 10.3390/jpm12091519
Lessons from implementing the Australian National Action Plan for Endometriosis
Armour, Mike, Avery, Jodie, Leonardi, Mathew, Van Niekerk, Leesa, Druitt, Marilla L., Parker, Melissa A., Girling, Jane E., McKinnon, Brett, Mikocka-Walus, Antonina, Ng, Cecilia H.M., O’Hara, Rebecca, Ciccia, Donna, Stanley, Katherine and Evans, Subhadra (2022). Lessons from implementing the Australian National Action Plan for Endometriosis. Reproduction and Fertility, 3 (3), C29-C39. doi: 10.1530/RAF-22-0003
McKinnon, Brett D., Lukowski, Samuel W., Mortlock, Sally, Crawford, Joanna, Atluri, Sharat, Subramaniam, Sugarniya, Johnston, Rebecca L., Nirgianakis, Konstantinos, Tanaka, Keisuke, Amoako, Akwasi, Mueller, Michael D. and Montgomery, Grant W. (2022). Altered differentiation of endometrial mesenchymal stromal fibroblasts is associated with endometriosis susceptibility. Communications Biology, 5 (1) 600, 600. doi: 10.1038/s42003-022-03541-3
Gene expression of the endocannabinoid system in endometrium through menstrual cycle
Tanaka, Keisuke, Amoako, Akwasi A., Mortlock, Sally, Rogers, Peter A. W., Holdsworth-Carson, Sarah J., Donoghue, Jacqueline F., Teh, Wan Tinn, Montgomery, Grant W. and McKinnon, Brett (2022). Gene expression of the endocannabinoid system in endometrium through menstrual cycle. Scientific Reports, 12 (1) 9400, 9400. doi: 10.1038/s41598-022-13488-4
Filby, Caitlin E., Wyatt, Katherine A., Mortlock, Sally, Cousins, Fiona L., McKinnon, Brett, Tyson, Kate E., Montgomery, Grant W. and Gargett, Caroline E. (2021). Comparison of organoids from menstrual fluid and hormone-treated endometrium: novel tools for gynecological research. Journal of Personalized Medicine, 11 (12) 1314. doi: 10.3390/jpm11121314
Ma, Lijuan, Andrieu, Thomas, McKinnon, Brett, Duempelmann, Lea, Peng, Ren-Wang, Wotzkow, Carlos, Müller, Christoph and Mueller, Michael D. (2021). Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions. The Journal of Steroid Biochemistry and Molecular Biology, 212 105943, 1-2. doi: 10.1016/j.jsbmb.2021.105943
Dual influence of TNFα on diverse in vitro models of ovarian cancer subtypes
Kocbek, Vida, Imboden, Sara, Nirgianakis, Kostantinos, Mueller, Michael and McKinnon, Brett (2021). Dual influence of TNFα on diverse in vitro models of ovarian cancer subtypes. Heliyon, 7 (2) e06099, e06099. doi: 10.1016/j.heliyon.2021.e06099
Genetic regulation of transcription in the endometrium in health and disease
Mortlock, Sally, McKinnon, Brett and Montgomery, Grant W. (2021). Genetic regulation of transcription in the endometrium in health and disease. Frontiers in Reproductive Health, 3 795464, 795464. doi: 10.3389/frph.2021.795464
Marla, S., Mortlock, S., Houshdaran, S., Fung, J., McKinnon, B., Holdsworth-Carson, S. J., Girling, J. E., Rogers, P. A. W., Giudice, L. C. and Montgomery, G. W. (2021). Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium. Molecular Human Reproduction, 27 (1) gaaa082. doi: 10.1093/molehr/gaaa082
Peritoneal fluid biomarkers in patients with endometriosis: a cross-sectional study
Nirgianakis, Konstantinos, Mckinnon, Brett, Ma, Lijuan, Imboden, Sara, Bersinger, Nick and Mueller, Michael D. (2021). Peritoneal fluid biomarkers in patients with endometriosis: a cross-sectional study. Hormone Molecular Biology and Clinical Investigation, 42 (2), 113-122. doi: 10.1515/hmbci-2019-0064
Nirgianakis, Konstantinos, Vaineau, Cloé, Agliati, Lia, McKinnon, Brett, Gasparri, Maria Luisa and Mueller, Michael D. (2020). Risk factors for non‐response and discontinuation of Dienogest in endometriosis patients: a cohort study. Acta Obstetricia et Gynecologica Scandinavica, 100 (1) aogs.13969, 30-40. doi: 10.1111/aogs.13969
Tissue specific regulation of transcription in endometrium and association with disease
Mortlock, Sally, Kendarsari, Raden I., Fung, Jenny N., Gibson, Greg, Yang, Fei, Restuadi, Restuadi, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Lukowski, Samuel W., Healey, Martin, Qi, Ting, Rogers, Peter A. W., Yang, Jian, McKinnon, Brett and Montgomery, Grant W. (2020). Tissue specific regulation of transcription in endometrium and association with disease. Human Reproduction, 35 (2), 377-393. doi: 10.1093/humrep/dez279
Nirgianakis, Konstantinos, Ma, Lijuan, McKinnon, Brett and Mueller, Michael D. (2020). Recurrence patterns after surgery in patients with different endometriosis subtypes: A long‐term hospital‐based cohort study. Journal of Clinical Medicine, 9 (2) 496. doi: 10.3390/jcm9020496
Tanaka, Keisuke, Mayne, Leah, Khalil, Akram, Baartz, David, Eriksson, Lars, Mortlock, Sally-Anne, Montgomery, Grant, McKinnon, Brett and Amoako, Akwasi A. (2020). The role of the endocannabinoid system in aetiopathogenesis of endometriosis: a potential therapeutic target. European Journal of Obstetrics and Gynecology and Reproductive Biology, 244, 87-94. doi: 10.1016/j.ejogrb.2019.11.012
Genotype-free demultiplexing of pooled single-cell RNA-seq
Xu, Jun, Falconer, Caitlin, Nguyen, Quan, Crawford, Joanna, McKinnon, Brett D., Mortlock, Sally, Senabouth, Anne, Andersen, Stacey, Chiu, Han Sheng, Jiang, Longda, Palpant, Nathan J., Yang, Jian, Mueller, Michael D., Hewitt, Alex W., Pébay, Alice, Montgomery, Grant W., Powell, Joseph E. and Coin, Lachlan J. M. (2019). Genotype-free demultiplexing of pooled single-cell RNA-seq. Genome Biology, 20 (1) 290, 290. doi: 10.1186/s13059-019-1852-7
Imboden, Sara, Tapia, Coya, Scheiwiller, Nadja, Kocbek, Vida, Altermatt, Hans J., Janzen, Jan, Mueller, Michael D. and McKinnon, Brett (2019). Early‐stage endometrial cancer, CTNNB1 mutations, and the relation between lymphovascular space invasion and recurrence. Acta Obstetricia et Gynecologica Scandinavica, 99 (2), 196-203. doi: 10.1111/aogs.13740
Nirgianakis, Konstantinos, Gasparri, Maria Luisa, Radan, Anda-Petronela, Villiger, Anna, McKinnon, Brett, Mosimann, Beatrice, Papadia, Andrea and Mueller, Michael D. (2018). Obstetric complications after laparoscopic excision of posterior deep infiltrating endometriosis: a case–control study. Fertility and Sterility, 110 (3), 459-466. doi: 10.1016/j.fertnstert.2018.04.036
Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W. and Montgomery, Grant W (2018). Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports, 8 (1) 11424, 11424. doi: 10.1038/s41598-018-29462-y
Progesterone resistance in endometriosis: an acquired property?
McKinnon, Brett, Mueller, Michael and Montgomery, Grant (2018). Progesterone resistance in endometriosis: an acquired property?. Trends in Endocrinology and Metabolism, 29 (8), 535-548. doi: 10.1016/j.tem.2018.05.006
Gajbhiye, Rahul, McKinnon, Brett, Mortlock, Sally, Mueller, Michael and Montgomery, Grant (2018). Genetic Variation at Chromosome 2q13 and Its Potential Influence on Endometriosis Susceptibility Through Effects on the IL-1 Family. Reproductive Sciences, 25 (9), 1933719118768688-1317. doi: 10.1177/1933719118768688
Sbracia, Marco, McKinnon, Brett, Scarpellini, Fabio, Marconi, Daniela, Rossi, Gabriele, Simmilion, Cedric, Mueller, Michael D., Barnea, Eytan R. and Mueller, Martin (2017). PreImplantation Factor in endometriosis: a potential role in inducing immune privilege for ectopic endometrium. PLoS ONE, 12 (9) e0184399, e0184399. doi: 10.1371/journal.pone.0184399
Grandi, Giovanni, Mueller, Michael D., Bersinger, Nick A., Facchinetti, Fabio and McKinnon, Brett D. (2017). The association between progestins, nuclear receptors expression and inflammation in endometrial stromal cells from women with endometriosis. Gynecological Endocrinology, 33 (9), 712-715. doi: 10.1080/09513590.2017.1314458
Nirgianakis, Konstantinos, Papadia, Andrea, Grandi, Giovanni, McKinnon, Brett, Bolla, Daniele and Mueller, Michael D. (2017). Laparoscopic management of ectopic pregnancies: a comparison between interstitial and “more distal” tubal pregnancies. Archives of Gynecology and Obstetrics, 295 (1), 95-101. doi: 10.1007/s00404-016-4191-x
Kocbek, Vida, Grandi, Giovanni, Blank, Fabian, Wotzkow, Carlos, Bersinger, Nick A., Mueller, Michael D., Kyo, Satoru and McKinnon, Brett D. (2016). TNFα-induced IKKβ complex activation influences epithelial, but not stromal cell survival in endometriosis. Molecular Human Reproduction, 22 (11), 768-777. doi: 10.1093/molehr/gaw054
Grandi, Giovanni, Mueller, Michael, Bersinger, Nick, Papadia, Andrea, Nirgianakis, Konstatinos, Cagnacci, Angelo and McKinnon, Brett (2016). Progestin suppressed inflammation and cell viability of tumor necrosis factor-α-stimulated endometriotic stromal cells. American Journal of Reproductive Immunology, 76 (4), 292-298. doi: 10.1111/aji.12552
Grandi, Giovanni, Mueller, Michael D., Papadia, Andrea, Kocbek, Vida, Bersinger, Nick A., Petraglia, Felice, Cagnacci, Angelo and McKinnon, Brett (2016). Inflammation influences steroid hormone receptors targeted by progestins in endometrial stromal cells from women with endometriosis. Journal of Reproductive Immunology, 117, 30-38. doi: 10.1016/j.jri.2016.06.004
Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics
McKinnon, Brett D., Kocbek, Vida, Nirgianakis, Kostantinos, Bersinger, Nick A. and Mueller, Michael D. (2016). Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics. Human Reproduction Update, 22 (3), 382-403. doi: 10.1093/humupd/dmv060
Does dienogest influence the inflammatory response of endometriotic cells? A systematic review
Grandi, Giovanni, Mueller, Michael, Bersinger, Nick A., Cagnacci, Angelo, Volpe, Annibale and McKinnon, Brett (2016). Does dienogest influence the inflammatory response of endometriotic cells? A systematic review. Inflammation Research, 65 (3), 183-192. doi: 10.1007/s00011-015-0909-7
Dienogest mediates midkine suppression in endometriosis
Nirgianakis, K., Grandi, G., McKinnon, B., Bersinger, N., Cagnacci, A. and Mueller, M. (2016). Dienogest mediates midkine suppression in endometriosis. Human Reproduction, 31 (9), 1981-1986. doi: 10.1093/humrep/dew180
Kollmann, Zahraa, Bersinger, Nick A., McKinnon, Brett D., Schneider, Sophie, Mueller, Michael D. and von Wolff, Michael (2015). Anti-Müllerian hormone and progesterone levels produced by granulosa cells are higher when derived from natural cycle IVF than from conventional gonadotropin-stimulated IVF. Reproductive Biology and Endocrinology, 13 (1) 21. doi: 10.1186/s12958-015-0017-0
Imboden, Sara, Papadia, Andrea, Nauwerk, Mélina, McKinnon, Brett, Kollmann, Zahraa, Mohr, Stefan, Lanz, Susanne and Mueller, Michael D. (2015). A comparison of radiocolloid and indocyanine green fluorescence imaging, sentinel lymph node mapping in patients with cervical cancer undergoing laparoscopic surgery. Annals of Surgical Oncology, 22 (13), 4198-4203. doi: 10.1245/s10434-015-4701-2
Zevallos, Héctor Barrera-Villa, Mckinnon, Brett, Tokushige, Natsuko, Mueller, Michael D., Fraser, Ian S. and Bersinger, Nick A. (2015). Detection of the pan neuronal marker PGP9.5 by immunohistochemistry and quantitative PCR in eutopic endometrium from women with and without endometriosis. Archives of Gynecology and Obstetrics, 291 (1), 85-91. doi: 10.1007/s00404-014-3379-1
Comparison of ovarian cancer markers in endometriosis favours HE4 over CA125
McKinnon, Brett, Mueller, Michael D., Nirgianakis, Konstantinos and Bersinger, Nick A. (2015). Comparison of ovarian cancer markers in endometriosis favours HE4 over CA125. Molecular Medicine Reports, 12 (4), 5179-5184. doi: 10.3892/mmr.2015.4062
Ghazal, Sanaz, Mckinnon, Brett, Zhou, Jichun, Mueller, Martin, Men, Yi, Yang, Lihua, Mueller, Michael, Flannery, Clare, Huang, Yingqun and Taylor, Hugh S. (2015). H19 IncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis. EMBO Molecular Medicine, 7 (8), 996-1003. doi: 10.15252/emmm.201505245
Inflammation and nerve fiber interaction in endometriotic pain
McKinnon, Brett D., Bertschi, Dominic, Bersinger, Nick A. and Mueller, Michael D. (2015). Inflammation and nerve fiber interaction in endometriotic pain. Trends in Endocrinology and Metabolism, 26 (1), 1-10. doi: 10.1016/j.tem.2014.10.003
Glucose transporter expression in eutopic endometrial tissue and ectopic endometriotic lesions
McKinnon, Brett, Bertschi, Dominic, Wotzkow, Carlos, Bersinger, Nick A, Evers, Jakob and Mueller, Michael D (2014). Glucose transporter expression in eutopic endometrial tissue and ectopic endometriotic lesions. Journal of Molecular Endocrinology, 52 (2), 169-79. doi: 10.1530/JME-13-0194
McKinnon, Brett D., Bertschi, Dominic, Wanner, Juilette, Bersinger, Nick A. and Mueller, Michael D. (2014). Hormonal contraceptive use and the prevalence of endometriotic lesions at different regions within the peritoneal cavity. BioMed Research International, 2014 590950, 1-6. doi: 10.1155/2014/590950
Laparoscopic management of bowel endometriosis: resection margins as a predictor of recurrence
Nirgianakis, Konstantinos, McKinnon, Brett, Imboden, Sara, Knabben, Laura, Gloor, Beat and Mueller, Michael D. (2014). Laparoscopic management of bowel endometriosis: resection margins as a predictor of recurrence. Acta Obstetricia et Gynecologica Scandinavica, 93 (12), 1262-1267. doi: 10.1111/aogs.12490
Nirgianakis, K., Bersinger, N. A., McKinnon, B., Kostov, P., Imboden, S. and Mueller, M. D. (2013). Regression of the inflammatory microenvironment of the peritoneal cavity in women with endometriosis by GnRHa treatment. European Journal of Obstetrics and Gynecology and Reproductive Biology, 170 (2), 550-554. doi: 10.1016/j.ejogrb.2013.08.010
McKinnon, Brett D., Evers, Jakob, Bersinger, Nick A. and Mueller, Michael D. (2013). Induction of the neurokinin 1 receptor by TNFα in endometriotic tissue provides the potential for neurogenic control over endometriotic lesion growth. Journal of Clinical Endocrinology and Metabolism, 98 (6), 2469-2477. doi: 10.1210/jc.2013-1019
Enhanced inflammatory activity of endometriotic lesions from the rectovaginal septum
Bertschi, Dominic, McKinnon, Brett D., Evers, Jakob, Bersinger, Nick A. and Mueller, Michael D. (2013). Enhanced inflammatory activity of endometriotic lesions from the rectovaginal septum. Mediators of Inflammation, 2013 450950, 1-7. doi: 10.1155/2013/450950
Bersinger, Nick A., Dechaud, Hervé, McKinnon, Brett and Mueller, Michael D. (2012). Analysis of cytokines in the peritoneal fluid of endometriosis patients as a function of the menstrual cycle stage using the Bio-Plex® platform. Archives of Physiology and Biochemistry, 118 (4), 210-218. doi: 10.3109/13813455.2012.687003
Santi, A., Felser, R., Bersinger, N. A., Wunder, D. M., McKinnon, B. and Mueller, M. D. (2012). The hysteroscopic view of infertility: the mid-secretory endometrium and treatment success towards pregnancy. Gynecological Surgery, 9 (2), 147-150. doi: 10.1007/s10397-011-0687-3
McKinnon, Brett, Bersinger, Nick A. and Mueller, Michael D. (2012). Peroxisome proliferating activating receptor gamma-independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones. Fertility and Sterility, 97 (3), 657-664. doi: 10.1016/j.fertnstert.2011.12.001
McKinnon, Brett, Bersinger, Nick A., Wotzkow, Carlos and Mueller, Michael D. (2012). Endometriosis-associated nerve fibers, peritoneal fluid cytokine concentrations, and pain in endometriotic lesions from different locations. Fertility and Sterility, 97 (2), 373-380. doi: 10.1016/j.fertnstert.2011.11.011
Santi, Alessandro, Felser, Rahel S., Mueller, Michael D., Wunder, Dorothea M., McKinnon, Brett and Bersinger, Nick A. (2011). Increased endometrial placenta growth factor (PLGF) gene expression in women with successful implantation. Fertility and Sterility, 96 (3), 663-668. doi: 10.1016/j.fertnstert.2011.06.039
Bersinger, Nick A., Günthert, Andreas R., McKinnon, Brett, Johann, Silke and Mueller, Michael D. (2011). Dose-response effect of interleukin (IL)-1β, tumour necrosis factor (TNF)-α, and interferon-γ on the in vitro production of epithelial neutrophil activating peptide-78 (ENA-78), IL-8, and IL-6 by human endometrial stromal cells. Archives of Gynecology and Obstetrics, 283 (6), 1291-1296. doi: 10.1007/s00404-010-1520-3
Bersinger, Nick A., Genewein, E. M., Müller, O., Altermatt, H. J., McKinnon, B. and Mueller, M. D. (2010). Morphology of human endometrial explants and secretion of stromal marker proteins in short-and long-term cultures. Gynecological Surgery, 7 (1), 75-80. doi: 10.1007/s10397-009-0520-4
PPAR-γ expression in peritoneal endometriotic lesions correlates with pain experienced by patients
McKinnon, Brett, Bersinger, Nick A., Huber, Alexander W., Kuhn, Annette and Mueller, Michael D. (2010). PPAR-γ expression in peritoneal endometriotic lesions correlates with pain experienced by patients. Fertility and Sterility, 93 (1), 293-296. doi: 10.1016/j.fertnstert.2009.07.980
Carrier-Mediated Thyroid Hormone Transport into Placenta by Placental Transthyretin
Landers, Kelly A., McKinnon, Brett D., Li, Huika, Subramaniam, V. Nathan, Mortimer, Robin H. and Richard, Kerry (2009). Carrier-Mediated Thyroid Hormone Transport into Placenta by Placental Transthyretin. Journal of Clinical Endocrinology and Metabolism, 94 (7), 2610-2616. doi: 10.1210/jc.2009-0048
Bersinger, Nick A., McKinnon, Brett, Kuhn, Annette, Santi, Alessandro and Mueller, Michael D. (2009). Pain symptoms and peritoneal fluid cytokine and marker concentrations in women with and without endometriosis. Journal of Endometriosis and Pelvic Pain Disorders, 1 (3-4), 137-149. doi: 10.1177/2284026509001003-404
Li, H, Richard, K, McKinnon, B and Mortimer, RH (2007). Effect of iodide on human choriogonadotropin, sodium-iodide symporter expression, and iodide uptake in BeWo choriocarcinoma cells. Journal of Clinical Endocrinology And Metabolism, 92 (10), 4046-4051. doi: 10.1210/jc.2006-2358
Synthesis of thyroid hormone binding proteins transthyretin and albumin by human trophoblast
McKinnon, Brett, Li, Huika, Richard, Kerry and Mortimer, Robin (2005). Synthesis of thyroid hormone binding proteins transthyretin and albumin by human trophoblast. Journal of Clinical Endocrinology and Metabolism, 90 (12), 6714-6720. doi: 10.1210/jc.2005-0696
Filby, Caitlin E., Wyatt, Katherine A., Mortlock, Sally, Cousins, Fiona L., McKinnon, Brett, Tyson, Kate, Montgomery, Grant W. and Gargett, Caroline E. (2022). Comparison of Organoids from Menstrual Fluid and Endometrium from Women Taking Hormonal Medication: Potential for Modelling Endometriosis. 69th Annual Meeting of the Society for Reproductive Investigation SRI 2022, Denver, CO United States, 15-19 March 2022. Heidelberg, Germany: Springer.
Mortlock, Sally, Fung, Jenny N., Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Lukowski, Samuel W., McKinnon, Brett D., Yang, Jian, McRae, Allan, Rogers, Peter A. W. and Montgomery, Grant W. (2019). Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.
Mueller, Martin, Sbracia, Marco, McKinnon, Brett, Scarpellini, Fabio, Marconi, Daniela, Rossi, Gabriele, Simmilion, Cedric, Mueller, Michael and Barnea, Eytan R. (2017). PreImplantation Factor* in Endometriosis: A Potential Role in Inducing Immune Privilege for Ectopic Endometrium. 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Orlando, FL United States, 15-18 March 2017. Thousand Oaks, CA United States: SAGE Publications.
McKinnon, Brett D., Kocbek, Vida, Bersinger, Nick A. and Mueller, Michael D. (2016). NF kappa B Mediated Alteration in Stromal Cell Inflammation Influences Epithelial Cell Survival in Endometriosis. 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation, Montreal, Canada, 16-19 March 2016. Heidelberg, Germany: Springer.
McKinnon, Brett, Bersinger, Nick A. and Mueller, Michael D. (2012). IKK beta activation correlates with inflammation and angiogenesis in both ovarian cancer and endometriotic lesions. -, -, 2012. Athens, Greece: Spandidos.
Megalin mediates internalisation of TTR into choriocarcinoma JEG-3 cells
Landers, K. A., McKinnon, B. D., Richard, K. and Mortimer, R. H. (2008). Megalin mediates internalisation of TTR into choriocarcinoma JEG-3 cells. 14th Meeting of the International-Federation-of-Placental-Associations/12th Meeting of the European-Placenta-Group (IFPA/EPG), Seggau Castle, Austria, 10-13 September 2008. London, United Kingdom: Elsevier .
Human trophoblast produces transthyretin
McKinnon, B., Li, H., Richard, K. and Mortimer, R. (2005). Human trophoblast produces transthyretin. London, United Kingdom: Elsevier .
Identifying endometriosis risk and disease variability by mapping endometrial stem cell maturation
(2023–2025) NHMRC IDEAS Grants
Generation of patient-derived micro-organoid spheres for precision medicine in endometriosis
(2023–2024) Metro North Hospital and Health Service
Environmental Risk Factors for Endometriosis
(2022–2023) Endometriosis Australia Ltd
Spatial resolved analysis of endometrial tissue
Master Philosophy — Principal Advisor
Other advisors:
Development of molecular techniques for endometriosis sub-typing and diagnosis
Doctor Philosophy — Principal Advisor
Other advisors:
Regulation of the endocannabinoid system in the endometrium across menstrual cycle and implications in endometriosis
Doctor Philosophy — Associate Advisor
Other advisors: