The University of Queensland

Stimuli-responsive sulfoxide polymer–protein conjugates with improved pharmacokinetics and tumor delivery

Ediriweera, Gayathri R., Chang, Yixin, Wang, Qiaoyun, Gong, Yutong, Akhter, Dewan T., Pang, Huiwen, Han, Felicity Y., Chen, Chunying, Whittaker, Andrew K. and Fu, Changkui (2023). Stimuli-responsive sulfoxide polymer–protein conjugates with improved pharmacokinetics and tumor delivery. Chemistry of Materials, 35 (17), 7252-7265. doi: 10.1021/acs.chemmater.3c01566

Fluoropolymer-MOF hybrids with switchable hydrophilicity for 19F MRI-monitored cancer therapy

Wang, Qiaoyun, Yu, Ye, Chang, Yixin, Xu, Xin, Wu, Min, Ediriweera, Gayathri R., Peng, Hui, Zhen, Xu, Jiang, Xiqun, Searles, Debra J., Fu, Changkui and Whittaker, Andrew K. (2023). Fluoropolymer-MOF hybrids with switchable hydrophilicity for 19F MRI-monitored cancer therapy. ACS Nano, 17 (9), 8483-8498. doi: 10.1021/acsnano.3c00694

Low-fouling gold nanorod theranostic agents enabled by a sulfoxide polymer coating

Chang, Yixin, Wang, Qiaoyun, Xu, Weizhi, Huang, Xumin, Xu, Xin, Han, Felicity Y., Qiao, Ruirui, Ediriweera, Gayathri R., Peng, Hui, Fu, Changkui, Liu, Kun and Whittaker, Andrew K. (2022). Low-fouling gold nanorod theranostic agents enabled by a sulfoxide polymer coating. Biomacromolecules, 23 (9), 3866-3874. doi: 10.1021/acs.biomac.2c00696

Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes

Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745

Non-viral vector-mediated gene therapy for ALS: challenges and future perspectives

Ediriweera, Gayathri R., Chen, Liyu, Yerbury, Justin J., Thurecht, Kristofer J. and Vine, Kara L. (2021). Non-viral vector-mediated gene therapy for ALS: challenges and future perspectives. Molecular Pharmaceutics, 18 (6), 2142-2160. doi: 10.1021/acs.molpharmaceut.1c00297

Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models

Simpson, Joshua D., Monteiro, Patrícia F., Ediriweera, Gayathri R., Prior, Amber R., Sonderegger, Stefan E., Bell, Craig A., Fletcher, Nicholas L., Alexander, Cameron and Thurecht, Kristofer J. (2021). Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models. ACS Applied Bio Materials, 4 (3) acsabm.0c01616, 2675-2685. doi: 10.1021/acsabm.0c01616

Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery

Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g

Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells

Simpson, Joshua D., Ediriweera, Gayathri R., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2019). Polymer design and component selection contribute to uptake, distribution & trafficking behaviours of polyethylene glycol hyperbranched polymers in live MDA-MB-468 breast cancer cells. Biomaterials Science, 7 (11), 4661-4674. doi: 10.1039/c9bm00957d