The University of Queensland

Characterisation of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive proteobacteria

Atack, John M., Srikhanta, Yogitha N., Djoko, Karrera Y., Welch, Jessica P., Hasri, Norain H. M., Steichen, Christopher T., Vanden Hoven, Rachel N., Grimmond, Sean M., Othman, Dk Seti Maimonah Pg, Kappler, Ulrike, Apicella, Michael A., Jennings, Michael P., Edwards, Jennifer L. and McEwan, Alastair G. (2013). Characterisation of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive proteobacteria. Journal of Bacteriology, 195 (11), 2632-2641. doi: 10.1128/JB.02062-12

A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms

Chen, Nathan H., Couñago, Rafael M., Djoko, Karrera Y., Jennings, Michael P., Apicella, Michael A., Kobe, Bostjan and McEwan, Alastair G. (2013). A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms. Antioxidants and Redox Signaling, 18 (7), 743-755. doi: 10.1089/ars.2012.4749

Copper redistribution in murine macrophages in response to Salmonella infection

Achard, Maud E. S., Stafford, Sian L., Bokil, Nilesh J., Chartres, Jy, Bernhardt, Paul V., Schembri, Mark A., Sweet, Matthew J. and McEwan, Alastair G. (2012). Copper redistribution in murine macrophages in response to Salmonella infection. Biochemical Journal, 444 (1), 51-57. doi: 10.1042/BJ20112180

A molecular mechanism for bacterial susceptibility to zinc

McDevitt, Christopher A., Ogunniyi, Abiodun D., Valkov, Eugene, Lawrence, Michael C., Kobe, Bostjan, McEwan, Alastair G. and Paton, James C. (2011). A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7 (11) e1002357, e1002357.1-e1002357.9. doi: 10.1371/journal.ppat.1002357

A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae

Kidd, Stephen P., Djoko, Karrera Y., Ng, JiaQi, Argente, M. Pilar, Jennings, Michael P. and McEwan, Alastair G. (2011). A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae. Metallomics, 3 (10), 1009-1018. doi: 10.1039/c1mt00127b

Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress

McEwan, Alistair G., Djoko, Karrera Y., Chen, Nathan H., Counago, Rafael L. M., Kidd, Stephen P., Potter, Adam J. and Jennings, Michael P. (2011). Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress. Advances in Microbial Physiology, 58, 1-22. doi: 10.1016/B978-0-12-381043-4.00001-5

The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence

Achard, Maud E. S., Tree, Jai J., Holden, James A., Simpfendorfer, Kim R., Wijburg, Odilia L. C., Strugnell, Richard A., Schembri, Mark A., Sweet, Matthew J., Jennings, Michael P. and McEwan, Alastair G. (2010). The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence. Infection and Immunity, 78 (5), 2312-2319. doi: 10.1128/IAI.01208-09

Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells

Potter, AJ, Kidd, SP, Edwards, JL, Falsetta, ML, Apicella, MA, Jennings, MP and McEwan, AG (2009). Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells. Journal of Infectious Diseases, 200 (2), 273-278. doi: 10.1086/599987

Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells

Potter, AJ, Kidd, SP, Edwards, JL, Falsetta, ML, Apicella, MA, Jennings, MP and McEwan, AG (2009). Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells. Journal of Infectious Diseases, 199 (2), 227-235. doi: 10.1086/595737

NmlR of Neisseria gonorrhoeae: a novel redox responsive transcription factor from the MerR family

Kidd, SP, Potter, AJ, Apicella, MA, Jennings, MP and McEwan, AG (2005). NmlR of Neisseria gonorrhoeae: a novel redox responsive transcription factor from the MerR family. Molecular Microbiology, 57 (6), 1676-1689. doi: 10.1111/j.1365-2958.2005.04773.x

Copper in immune cells

Djoko, Karrera Y., Achard, Maud E. S. and McEwan, Alastair G. (2013). Copper in immune cells. Metals in Cells. (pp. 409-420) edited by Valeria Culotta and Robert A. Scott. Hoboken, New Jersey, USA: John Wiley & Sons. doi: 10.1002/9781119951438

Microbial molybdenum-containing enzymes in respiration: Structural and functional aspects

McEwan, A. G., Kappler, U. and Mc Devitt, C. (2004). Microbial molybdenum-containing enzymes in respiration: Structural and functional aspects. Respiration in Archaea and Bacteria. (pp. 176-202) edited by D. Zannoni. Dordrecht, Netherlands: Kluwer.

Neurodegenerative disease treatment drug PBT2 breaks intrinsic polymyxin resistance in Gram-positive bacteria

De Oliveira, David M. P., Keller, Bernhard, Hayes, Andrew J., Ong, Cheryl-Lynn Y., Harbison-Price, Nichaela, El-Deeb, Ibrahim M., Li, Gen, Keller, Nadia, Bohlmann, Lisa, Brouwer, Stephan, Turner, Andrew G., Cork, Amanda J., Jones, Thomas R., Paterson, David L., McEwan, Alastair G., Davies, Mark R., McDevitt, Christopher A., Itzstein, Mark von and Walker, Mark J. (2022). Neurodegenerative disease treatment drug PBT2 breaks intrinsic polymyxin resistance in Gram-positive bacteria. Antibiotics, 11 (4) 449, 449. doi: 10.3390/antibiotics11040449

Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells

Hosmer, Jennifer, Nasreen, Marufa, Dhouib, Rabeb, Essilfie, Ama-Tawiah, Schirra, Horst Joachim, Henningham, Anna, Fantino, Emmanuelle, Sly, Peter, McEwan, Alastair G. and Kappler, Ulrike (2022). Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells. PLoS Pathogens, 18 (1) e1010209, e1010209. doi: 10.1371/journal.ppat.1010209

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Brazel, Erin B., Tan, Aimee, Neville, Stephanie L., Iverson, Amy R., Udagedara, Saumya R., Cunningham, Bliss A., Sikanyika, Mwilye, De Oliveira, David M.P., Keller, Bernhard, Bohlmann, Lisa, El-Deeb, Ibrahim M., Ganio, Katherine, Eijkelkamp, Bart A., McEwan, Alastair G., von Itzstein, Mark, Maher, Megan J., Walker, Mark J., Rosch, Jason W. and McDevitt, Christopher A. (2022). Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model. Cell Reports, 38 (2) 110202, 1-18. doi: 10.1016/j.celrep.2021.110202

The DmsABC sulfoxide reductase supports virulence in non-typeable Haemophilus influenzae

Dhouib, Rabeb, Nasreen, Marufa, Othman, Dk Seti Maimonah Pg, Ellis, Daniel, Lee, Simon, Essilfie, Ama-Tawiah, Hansbro, Philip M., McEwan, Alastair G. and Kappler, Ulrike (2021). The DmsABC sulfoxide reductase supports virulence in non-typeable Haemophilus influenzae. Frontiers in Microbiology, 12 686833, 686833. doi: 10.3389/fmicb.2021.686833

The alternative sigma factor RpoE2 Is involved in the stress response to hypochlorite and in vivo survival of Haemophilus influenzae

Nasreen, Marufa, Fletcher, Aidan, Hosmer, Jennifer, Zhong, Qifeng, Essilfie, Ama-Tawiah, McEwan, Alastair G. and Kappler, Ulrike (2021). The alternative sigma factor RpoE2 Is involved in the stress response to hypochlorite and in vivo survival of Haemophilus influenzae. Frontiers in Microbiology, 12 637213, 637213. doi: 10.3389/fmicb.2021.637213

Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes

Struwe, Michel A., Kalimuthu, Palraj, Luo, Zhenyao, Zhong, Qifeng, Ellis, Daniel, Yang, Jing, Khadanand, K.C., Harmer, Jeffrey R., Kirk, Martin L., McEwan, Alastair G., Clement, Bernd, Bernhardt, Paul V., Kobe, Bostjan and Kappler, Ulrike (2021). Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes. Journal of Biological Chemistry, 296 100672, 1-16. doi: 10.1016/j.jbc.2021.100672

Role of glutathione in buffering excess intracellular copper in Streptococcus pyogenes

Stewart, Louisa J., Ong, Cheryl-Lynn Y., Zhang, May M., Brouwer, Stephan, McIntyre, Liam, Davies, Mark R., Walker, Mark J., McEwan, Alastair G., Waldron, Kevin J. and Djoko, Karrera Y. (2020). Role of glutathione in buffering excess intracellular copper in Streptococcus pyogenes. mBio, 11 (6) e02804-20, 1-19. doi: 10.1128/mBio.02804-20

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791

Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infection

Nasreen, Marufa, Dhouib, Rabeb, Hosmer, Jennifer, Wijesinghe, Hewa Godage Sithija, Fletcher, Aidan, Mahawar, Manish, Essilfie, Ama-Tawiah, Blackall, Patrick J., McEwan, Alastair G. and Kappler, Ulrike (2020). Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infection. ACS Infectious Diseases, 6 (7), 1928-1939. doi: 10.1021/acsinfecdis.0c00242

Two distinct L-lactate dehydrogenases play a role in the survival of Neisseria gonorrhoeae in cervical epithelial cells

Chen, Nathan H., Ong, Cheryl-Lynn Y, O'Sullivan, Jonathan, Ibranovic, Ines, Davey, Krystelle, Edwards, Jennifer L. and McEwan, Alastair G. (2020). Two distinct L-lactate dehydrogenases play a role in the survival of Neisseria gonorrhoeae in cervical epithelial cells. The Journal of infectious diseases, 221 (3), 449-453. doi: 10.1093/infdis/jiz468

Dietary zinc and the control of Streptococcus pneumoniae infection

Eijkelkamp, Bart A., Morey, Jacqueline R., Neville, Stephanie L., Tan, Aimee, Pederick, Victoria G., Cole, Nerida, Singh, Prashina P., Ong, Cheryl-Lynn Y., Gonzalez de Vega, Raquel, Clases, David, Cunningham, Bliss A., Hughes, Catherine E., Comerford, Iain, Brazel, Erin B., Whittall, Jonathan J., Plumptre, Charles D., McColl, Shaun R., Paton, James C., McEwan, Alastair G., Doble, Philip A. and McDevitt, Christopher A. (2019). Dietary zinc and the control of Streptococcus pneumoniae infection. PLOS Pathogens, 15 (8) e1007957, e1007957. doi: 10.1371/journal.ppat.1007957

New insights into the molecular physiology of sulfoxide reduction in bacteria

Kappler, Ulrike, Nasreen, Marufa and McEwan, Alastair (2019). New insights into the molecular physiology of sulfoxide reduction in bacteria. Advances in Microbial Physiology, 75, 1-51. doi: 10.1016/bs.ampbs.2019.05.001

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M. and Korotkova, Natalia (2019). Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nature Chemical Biology, 15 (5), 463-471. doi: 10.1038/s41589-019-0251-4

Metabolic analyses reveal common adaptations in two invasive Haemophilus influenzae strains

Muda, Noor Marian, Nasreen, Marufa, Dhouib, Rabeb, Hosmer, Jennifer, Hill, Julian, Mahawar, Manish, Schirra, Horst Joachim, McEwan, Alastair G. and Kappler, Ulrike (2019). Metabolic analyses reveal common adaptations in two invasive Haemophilus influenzae strains. Pathogens and Disease, 77 (2) ftz015. doi: 10.1093/femspd/ftz015

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress

Turner, Andrew G., Djoko, Karrera Y., Ong, Cheryl-Lynn Y., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2019). Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress. Biochemical Journal, 476 (3), 595-611. doi: 10.1042/BCJ20180902

Handling of nutrient copper in the bacterial envelope

Stewart, Louisa J., Thaqi, Denis, Kobe, Bostjan, McEwan, Alastair G., Waldron, Kevin J. and Djoko, Karrera Y. (2019). Handling of nutrient copper in the bacterial envelope. Metallomics, 11 (1), 50-63. doi: 10.1039/c8mt00218e

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18

The role of zinc acquisition and zinc tolerance in group A streptococcal infection

Ong, Cheryl-Lynn Y., Berking, Olga, Walker, Mark J. and McEwan, Alastair G. (2018). The role of zinc acquisition and zinc tolerance in group A streptococcal infection. Infection and Immunity, 86 (6) e00048-18, e00048-18. doi: 10.1128/IAI.00048-18

Copper ions and coordination complexes as novel carbapenem adjuvants

Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17

Copper(II)-bis(thiosemicarbazonato) complexes as anti-chlamydial agents

Marsh, James W., Djoko, Karrera Y., McEwan, Alastair G. and Huston, Wilhelmina M. (2017). Copper(II)-bis(thiosemicarbazonato) complexes as anti-chlamydial agents. Pathogens and Disease, 75 (7) ftx084, 1-4. doi: 10.1093/femspd/ftx084

Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli

Djoko, Karrera Y., Phan, Minh-Duy, Peters, Kate M., Walker, Mark J. , Schembri, Mark A. and McEwan, Alastair G. (2017). Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), 6818-6823. doi: 10.1073/pnas.1620232114

The PerR-regulated P1B-4 type ATPase (PmtA) acts as a ferrous iron efflux pump in Streptococcus pyogenes

Turner, Andrew G., Ong, Cheryl-lynn Y., Djoko, Karrera Y., West, Nicholas P., Davies, Mark R., McEwan, Alastair G. and Walker, Mark J. (2017). The PerR-regulated P1B-4 type ATPase (PmtA) acts as a ferrous iron efflux pump in Streptococcus pyogenes. Infection and Immunity, 85 (6) e00140-17, e00140-17.1-e00140-17.13. doi: 10.1128/IAI.00140-17

Draft genome sequences of three nontypeable strains of Haemophilus influenzae, C188, R535, and 1200, isolated from different types of disease

Kappler, Ulrike, Dhouib, Rabeb, Nair, Remya Purushothaman and McEwan, Alastair G. (2017). Draft genome sequences of three nontypeable strains of Haemophilus influenzae, C188, R535, and 1200, isolated from different types of disease. Genome Announcements, 5 (12) e00035-17, e00035-17. doi: 10.1128/genomeA.00035-17

Transition metal homeostasis in Streptococcus pyogenes and Streptococcus pneumoniae

Turner, Andrew G., Ong, Cheryl-lynn Y., Walker, Mark J., Djoko, Karrera Y. and McEwan, Alastair G. (2017). Transition metal homeostasis in Streptococcus pyogenes and Streptococcus pneumoniae. Advances in Microbial Physiology, 70, 123-191. doi: 10.1016/bs.ampbs.2017.01.002

A novel, molybdenum-containing methionine sulfoxide reductase supports survival of Haemophilus influenzae in an in vivo model of infection

Dhouib, Rabeb, Othman, Dk. Seti Maimonah Pg, Lin, Victor, Lai, Xuanjie J., Wijesinghe, Hewa G. S., Essilfie, Ama-Tawiah, Davis, Amanda, Nasreen, Marufa, Bernhardt, Paul V., Hansbro, Philip M., McEwan, Alastair G. and Kappler, Ulrike (2016). A novel, molybdenum-containing methionine sulfoxide reductase supports survival of Haemophilus influenzae in an in vivo model of infection. Frontiers in Microbiology, 7 (NOV) 1743, 1743. doi: 10.3389/fmicb.2016.01743

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection

Shepherd, Mark, Achard, Maud E. S., Idris, Adi, Totsika, Makrina, Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Ribeiro, Cláudia A., Holyoake, Louise V., Ladakis, Dimitrios, Ulett, Glen C., Sweet, Matthew J., Poole, Robert K., McEwan, Alastair G. and Schembri, Mark A. (2016). The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection. Scientific Reports, 6 (1) 35285, 35285. doi: 10.1038/srep35285

Functional analysis of an feoB mutant in Clostridium perfringens strain 13

Awad, Milena M., Cheung, Jackie K., Tan, Joanne E., McEwan, Alastair G., Lyras, Dena and Rood, Julian I. (2016). Functional analysis of an feoB mutant in Clostridium perfringens strain 13. Anaerobe, 41, 10-17. doi: 10.1016/j.anaerobe.2016.05.005

Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region

Couñago, Rafael M., Chen, Nathan H., Chang, Chiung-Wen, Djoko, Karrera Y., McEwan, Alastair G. and Kobe, Bostjan (2016). Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region. Nucleic Acids Research, 44 (14), 6981-6993. doi: 10.1093/nar/gkw543

Formaldehyde stress responses in bacterial pathogens

Chen, Nathan H., Djoko, Karrera Y., Veyrier, Frédéric J. and McEwan, Alastair G. (2016). Formaldehyde stress responses in bacterial pathogens. Frontiers in Microbiology, 7 (MAR) 257, 257.1-257.17. doi: 10.3389/fmicb.2016.00257

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061

Defence against methylglyoxal in Group A Streptococcus: a role for Glyoxylase I in bacterial virulence and survival in neutrophils?

Zhang, May M., Ong, Cheryl-lynn, Walker, Mark J. and McEwan, Alastair G. (2015). Defence against methylglyoxal in Group A Streptococcus: a role for Glyoxylase I in bacterial virulence and survival in neutrophils?. Pathogens and Disease, 74 (2), ftv122. doi: 10.1093/femspd/ftv122

Maturation of molybdoenzymes and its influence on the pathogenesis of non-typeable Haemophilus influenzae

Dhouib, Rabeb, Othman, Dk S. M. Pg, Essilfie, Ama-Tawiah, Hansbro, Phil M., Hanson, Jeffrey O., McEwan, Alastair G. and Kappler, Ulrike (2015). Maturation of molybdoenzymes and its influence on the pathogenesis of non-typeable Haemophilus influenzae. Frontiers in Microbiology, 6 (1219) 1219, 1-11. doi: 10.3389/fmicb.2015.01219

Copper(II)-bis(thiosemicarbazonato) complexes as antibacterial agents: insights into their mode of action and potential as therapeutics

Djoko, Karrera Y., Schembri, Maira M., Donnelly, Paul S., Schembri, Mark A., Shafer, William M. and McEwan, Alastair G. (2015). Copper(II)-bis(thiosemicarbazonato) complexes as antibacterial agents: insights into their mode of action and potential as therapeutics. Antimicrobial Agents and Chemotherapy, 59 (10), 6444-6453. doi: 10.1128/aac.01289-15

The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens.

Djoko, Karrera Y, Ong, Cheryl-lynn Y, Walker, Mark J and McEwan, Alastair G (2015). The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens.. Journal of Biological Chemistry, 290 (31), 18954-18961. doi: 10.1074/jbc.R115.647099

A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae.

Atack, John M., Srikhanta, Yogitha N., Fox, Kate L., Jurcisek, Joseph A., Brockman, KL, Clark, Tyson A., Boitano, Matthew, Power, Peter M., Jen, Freda E.-C., McEwan, Alastair G., Grimmond, Sean M., Smith, Arnold L., Barenkamp, Stephen J., Korlach, Jonas, Bakaletz, Lauren O. and Jennings, Michael P. (2015). A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae.. Nature Communications, 6 (Art No.: 7828) 7828, 7828. doi: 10.1038/ncomms8828

A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria.

Jen, Freda E. C., Djoko, Karrera Y., Bent, Stephen J., Day, Christopher J., McEwan, Alastair G. and Jennings, Michael P. (2015). A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria.. The FASEB Journal, 29 (9), 3828-3838. doi: 10.1096/fj.15-270751

Zinc disrupts central carbon metabolism and capsule biosynthesis in Streptococcus pyogenes.

Ong, Cheryl-lynnY., Walker, Mark J. and McEwan, Alastair G. (2015). Zinc disrupts central carbon metabolism and capsule biosynthesis in Streptococcus pyogenes.. Scientific Reports, 5 (Art No.: 10799) 10799, 10799. doi: 10.1038/srep10799.

Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulence

Turner, Andrew G., Ong, Cheryl-lynn, Gillen, Christine M., Davies, Mark R., West, Nicholas P., McEwan, Alastair G. and Walker, Mark J. (2015). Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulence. mBio, 6 (2) e00278-15, 1-10. doi: 10.1128/mBio.00278-15

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

Begg, Stephanie L., Eijkelkamp, Bart A., Luo, Zhenyao, Couñago, Rafael M., Morey, Jacqueline R., Maher, Megan J., Ong, Cheryl-lynn Y., McEwan, Alastair G., Kobe, Bostjan, O'Mara, Megan L., Paton, James C. and McDevitt, Christopher A. (2015). Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nature Communications, 6 (6418) 6418, 1-11. doi: 10.1038/ncomms7418

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

Bajaj, Megha, Mamidyala, Sreeman K., Zuegg, Johannes, Begg, Stephanie L., Ween, Miranda P., Luo, Zhenyao, Huang, Johnny Xiao, McEwan, Alastair G., Kobe, Bostjan, Paton, James C., McDevitt, Christopher A. and Cooper, Matthew A. (2015). Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach. ACS Chemical Biology, 10 (6), 1511-1520. doi: 10.1021/cb501032x

Electrochemically mediated enantioselective reduction of chiral sulfoxides

Chen, Kuan I., Challinor, Victoria L., Kielmann, Linda, Sharpe, Philip C., De Voss, James J., Kappler, Ulrike, McEwan, Alastair G. and Bernhardt, Paul V. (2014). Electrochemically mediated enantioselective reduction of chiral sulfoxides. Journal of Biological Inorganic Chemistry, 20 (2), 395-402. doi: 10.1007/s00775-014-1215-5

Inhibition of respiratory Complex I by copper(ii)-bis(thiosemicarbazonato) complexes

Djoko, Karrera Y., Donnelly, Paul S. and McEwan, Alastair G. (2014). Inhibition of respiratory Complex I by copper(ii)-bis(thiosemicarbazonato) complexes. Metallomics, 6 (12), 2250-2259. doi: 10.1039/C4MT00226A

An antimicrobial role for zinc in innate immune defence against group A streptococcus

Ong, Cheryl-lynn Y., Gillen, Christine M., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2014). An antimicrobial role for zinc in innate immune defence against group A streptococcus. Journal of Infectious Diseases, 209 (10), 1500-1508. doi: 10.1093/infdis/jiu053

A role for lactate dehydrogenases in the survival of Neisseria gonorrhoeae in human polymorphonuclear leukocytes and cervical epithelial cells

Atack, John M., Ibranovic, Ines, Ong, Cheryl-lynn Y., Djoko, Karrera Y., Chen, Nathan H., vanden Hoven, Rachel, Jennings, Michael P., Edwards, Jennifer L. and McEwan, Alastair G. (2014). A role for lactate dehydrogenases in the survival of Neisseria gonorrhoeae in human polymorphonuclear leukocytes and cervical epithelial cells. Journal of Infectious Diseases, 210 (8), 1311-1318. doi: 10.1093/infdis/jiu230

Metabolic versatility in Haemophilus influenzae: a metabolomic and genomic analysis

Othman, Dk Seti Maimonah Pg, Schirra, Horst, McEwan, Alastair G. and Kappler, Ulrike (2014). Metabolic versatility in Haemophilus influenzae: a metabolomic and genomic analysis. Frontiers in Microbiology, 5 (MAR) 69, 69.1-69.10. doi: 10.3389/fmicb.2014.00069

Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in streptococcus pneumoniae

Eijkelkamp, Bart A., Morey, Jacqueline R., Ween, Miranda P., Ong, Cheryl-lynn Y., McEwan, Alastair G., Paton, James C. and McDevitt, Christopher A. (2014). Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in streptococcus pneumoniae. PLoS One, 9 (2) e89427, e89427. doi: 10.1371/journal.pone.0089427

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

Djoko, Karrera Y., Paterson, Brett M., Donnelly, Paul S. and McEwan, Alastair G. (2014). Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action. Metallomics, Advance Article (4), 1-10. doi: 10.1039/C3MT00348E

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

Couñago, Rafael M., Ween, Miranda P., Begg, Stephanie L., Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L., Cooper, Matthew A., McEwan, Alastair G., Paton, James C., Kobe, Bostjan and McDevitt, Christopher A. (2014). Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology, 10 (1), 35-41. doi: 10.1038/nCHeMBIO.1382

Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica Serovar typhimurium

Shepherd, Mark, Heras, Begona, Achard, Maud E. S., King, Gordon J., Argente, M. Pilar, Kurth, Fabian, Taylor, Samantha L., Howard, Mark J., King, Nathan P., Schembri, Mark A. and McEwan, Alastair G. (2013). Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica Serovar typhimurium. Antioxidants and Redox Signaling, 19 (13), 1494-1506. doi: 10.1089/ars.2012.4939

Antimicrobial action of copper is amplified via inhibition of heme biosynthesis

Djoko, Karrera Y. and McEwan, Alastair G. (2013). Antimicrobial action of copper is amplified via inhibition of heme biosynthesis. ACS Chemical Biology, 8 (10), 2217-2223. doi: 10.1021/cb4002443

An antioxidant role for catecholate siderophores in Salmonella

Achard, Maud E. S, Chen, Kaiwen W., Sweet, Matthew J., Watts, Rebecca E., Schroder, Kate, Schembri, Mark A. and McEwan, Alastair G. (2013). An antioxidant role for catecholate siderophores in Salmonella. Biochemical Journal, 454 (3), 543-549. doi: 10.1042/BJ20121771

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

Stafford, Sian L., Bokil, Nilesh J., Achard, Maud E. S., Kapetanovic, Ronan, Schembri, Mark A., McEwan, Alastair G. and Sweet, Matthew J. (2013). Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper. Bioscience Reports, 33 (4), 541-554. doi: 10.1042/BSR20130014

Characterisation of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive proteobacteria

Atack, John M., Srikhanta, Yogitha N., Djoko, Karrera Y., Welch, Jessica P., Hasri, Norain H. M., Steichen, Christopher T., Vanden Hoven, Rachel N., Grimmond, Sean M., Othman, Dk Seti Maimonah Pg, Kappler, Ulrike, Apicella, Michael A., Jennings, Michael P., Edwards, Jennifer L. and McEwan, Alastair G. (2013). Characterisation of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive proteobacteria. Journal of Bacteriology, 195 (11), 2632-2641. doi: 10.1128/JB.02062-12

A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms

Chen, Nathan H., Couñago, Rafael M., Djoko, Karrera Y., Jennings, Michael P., Apicella, Michael A., Kobe, Bostjan and McEwan, Alastair G. (2013). A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms. Antioxidants and Redox Signaling, 18 (7), 743-755. doi: 10.1089/ars.2012.4749

Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR

Ong, Cheryl-lynn Y., Potter, Adam J., Trappetti, Claudia, Walker, Mark J., Jennings, Michael P., Paton, James C. and McEwan, Alastair G. (2013). Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR. Infection and Immunity, 81 (2), 421-429. doi: 10.1128/IAI.00805-12

A glutathione-based system for defense against carbonyl stress in Haemophilus influenzae

Kidd, Stephen P., Jiang, Donald, Tikhomirova, Alexandra, Jennings, Michael P. and McEwan, Alastair G. (2012). A glutathione-based system for defense against carbonyl stress in Haemophilus influenzae. BMC Microbiology, 12 159, 159-1-159-6. doi: 10.1186/1471-2180-12-159

Copper redistribution in murine macrophages in response to Salmonella infection

Achard, Maud E. S., Stafford, Sian L., Bokil, Nilesh J., Chartres, Jy, Bernhardt, Paul V., Schembri, Mark A., Sweet, Matthew J. and McEwan, Alastair G. (2012). Copper redistribution in murine macrophages in response to Salmonella infection. Biochemical Journal, 444 (1), 51-57. doi: 10.1042/BJ20112180

Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress

Djoko, Karrera Y., Franiek, Jessica A., Edwards, Jennifer L., Falsetta, Megan L., Kidd, Stephen P., Potter, Adam J., Chen, Nathan H., Apicella, Michael A., Jennings, Michael P. and McEwan, Alastair G. (2012). Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress. Infection and Immunity, 80 (3), 1065-1071. doi: 10.1128/IAI.06163-11

A molecular mechanism for bacterial susceptibility to zinc

McDevitt, Christopher A., Ogunniyi, Abiodun D., Valkov, Eugene, Lawrence, Michael C., Kobe, Bostjan, McEwan, Alastair G. and Paton, James C. (2011). A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7 (11) e1002357, e1002357.1-e1002357.9. doi: 10.1371/journal.ppat.1002357

A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae

Kidd, Stephen P., Djoko, Karrera Y., Ng, JiaQi, Argente, M. Pilar, Jennings, Michael P. and McEwan, Alastair G. (2011). A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae. Metallomics, 3 (10), 1009-1018. doi: 10.1039/c1mt00127b

Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress

McEwan, Alistair G., Djoko, Karrera Y., Chen, Nathan H., Counago, Rafael L. M., Kidd, Stephen P., Potter, Adam J. and Jennings, Michael P. (2011). Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress. Advances in Microbial Physiology, 58, 1-22. doi: 10.1016/B978-0-12-381043-4.00001-5

The composition and metabolic phenotype of Neisseria gonorrhoeae biofilms

Falsetta, Megan L., Steichen, Christopher T., McEwan, Alastair G., Cho, Christine, Ketterer, Margaret, Shao, Jianqiang, Hunt, Jason, Jennings, Michael P. and Apicella, Michael A. (2011). The composition and metabolic phenotype of Neisseria gonorrhoeae biofilms. Frontiers in Microbiology, 2 (APR). doi: 10.3389/fmicb.2011.00075

Cobalt hexaamine mediated electrocatalytic voltammetry of dimethyl sulfoxide reductase: Driving force effects on catalysis

Chen, Kuan-I., McEwan, Alastair G. and Bernhardt, Paul V. (2011). Cobalt hexaamine mediated electrocatalytic voltammetry of dimethyl sulfoxide reductase: Driving force effects on catalysis. Journal of Biological Inorganic Chemistry, 16 (2), 227-234. doi: 10.1007/s00775-010-0719-x

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae

Ogunniyi, A. D., Mahdi, L. K., Jennings, M. P., McEwan, A. G., McDevitt, C. A., Van der Hoek, M. B., Bagley, C. J., Hoffmann, P., Gould, K. A. and Paton, J. C. (2010). Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae. Journal of Bacteriology, 192 (17), 4489-4497. doi: 10.1128/JB.00064-10

The MerR/NmlR family transcription factor of Streptococcus pneumoniae responds to carbonyl stress and modulates hydrogen peroxide production

Potter, A. J., Kidd, S. P., McEwan, A. G. and Paton, J. C. (2010). The MerR/NmlR family transcription factor of Streptococcus pneumoniae responds to carbonyl stress and modulates hydrogen peroxide production. Journal of Bacteriology, 192 (15), 4063-4066. doi: 10.1128/JB.00383-10

Molecular analysis of type 3 fimbrial genes from Escherichia coli, Klebsiella and Citrobacter species

Ong, Cheryl-lynn Y., Beatson, Scott A., Totsika, Makrina, Forestier, Christiane, McEwan, Alastair G. and Schembri, Mark A. (2010). Molecular analysis of type 3 fimbrial genes from Escherichia coli, Klebsiella and Citrobacter species. BMC Microbiology, 10 (183) 183, 1-12. doi: 10.1186/1471-2180-10-183

Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium

Heras, B, Totsika, M, Jarrott, R, Shouldice, SR, Guncar, G, Achard, MES, Wells, TJ, Argente, MP, McEwan, AG and Schembri, MA (2010). Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. Journal of Biological Chemistry, 285 (24), 18423-18432. doi: 10.1074/jbc.M110.101360

Anaerobic metabolism occurs in the substratum of gonococcal biofilms and may be sustained in part by nitric oxide

Falsetta, Megan L., McEwan, Alastair G., Jennings, Michael P. and Apicella, Michael A. (2010). Anaerobic metabolism occurs in the substratum of gonococcal biofilms and may be sustained in part by nitric oxide. Infection and Immunity, 78 (5), 2320-2328. doi: 10.1128/IAI.01312-09

The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence

Achard, Maud E. S., Tree, Jai J., Holden, James A., Simpfendorfer, Kim R., Wijburg, Odilia L. C., Strugnell, Richard A., Schembri, Mark A., Sweet, Matthew J., Jennings, Michael P. and McEwan, Alastair G. (2010). The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence. Infection and Immunity, 78 (5), 2312-2319. doi: 10.1128/IAI.01208-09

Manganese regulation of virulence factors and oxidative stress resistance in Neisseria gonorrhoeae

Wu, Hsing-Ju, Seib, Kate L., Srikhanta, Yogitha N., Edwards, Jennifer, Kidd, Stephen P., Maguire,Tina L., Hamilton, Amanda, Pan, Kuan-Tin, Hsiao, He-Hsuan, Yao, Chen-Wen, Grimmond, Sean M., Apicella, Michael A., McEwan, Alastair G., Wang, Andrew H-J. and Jennings, Michael P. (2010). Manganese regulation of virulence factors and oxidative stress resistance in Neisseria gonorrhoeae. Journal of Proteomics, 73 (5), 899-916. doi: 10.1016/j.jprot.2009.12.001

A periplasmic thioredoxin-like protein plays a role in defense against oxidative stress in Neisseria gonorrhoeae

Achard, Maud E. S., Hamilton, Amanda J., Dankowski, Tarek, Heras, Begona, Schembri, Mark A., Edwards, Jennifer L., Jennings, Michael P. and McEwan, Alastair G. (2009). A periplasmic thioredoxin-like protein plays a role in defense against oxidative stress in Neisseria gonorrhoeae. Infection And Immunity, 77 (11), 4934-4939. doi: 10.1128/IAI.00714-09

Probing the archaeal diversity of a mixed thermophilic bioleaching culture by TGGE and FISH

Mikkelsen, Deirdre, Kappler, Ulrike, McEwan, Alastair G. and Sly, Lindsay I. (2009). Probing the archaeal diversity of a mixed thermophilic bioleaching culture by TGGE and FISH. Systematic and Applied Microbiology, 32 (7), 501-513. doi: 10.1016/j.syapm.2009.06.001

Transcriptional profiling identifies the metabolic phenotype of gonococcal biofilms

Falsetta, Megan L., Bair, Thomas B., Ku, Shan Chi, Vanden Hoven, Rachel N., Steichen, Christopher T., McEwan, Alastair G., Jennings, Michael P. and Apicella, Michael A. (2009). Transcriptional profiling identifies the metabolic phenotype of gonococcal biofilms. Infection and Immunity, 77 (9), 3522-3532. doi: 10.1128/IAI.00036-09

Conjugative plasmid transfer and adhesion dynamics in an Escherichia coli Biofilm

Ong, Cheryl-Lynn Y., Beatson, Scott A., McEwan, Alastair G. and Schembri, Mark A. (2009). Conjugative plasmid transfer and adhesion dynamics in an Escherichia coli Biofilm. Applied and Environmental Microbiology, 75 (21), 6783-6791. doi: 10.1128/AEM.00974-09

Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells

Potter, AJ, Kidd, SP, Edwards, JL, Falsetta, ML, Apicella, MA, Jennings, MP and McEwan, AG (2009). Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells. Journal of Infectious Diseases, 200 (2), 273-278. doi: 10.1086/599987

New insights into the protective effect of manganese against oxidative stress

McEwan, Alastair G. (2009). New insights into the protective effect of manganese against oxidative stress. Molecular Microbiology, 72 (4), 812-814. doi: 10.1111/j.1365-2958.2009.06700.x

Molecular ecology of a facultative swine waste lagoon.

Goh, S. H. M., Mabbett, A. N., Welch, J. P., Hall, S. J. and McEwan, A. G. (2009). Molecular ecology of a facultative swine waste lagoon.. Letters in Applied Microbiology, 48 (4), 486-492. doi: 10.1111/j.1472-765X.2009.02560.x

Mediated electrochemistry of dimethyl sulfoxide reductase from Rhodobacter capsulatus

Kuan-I Chen, McEwan, Alastair G. and Bernhardt, Paul V. (2009). Mediated electrochemistry of dimethyl sulfoxide reductase from Rhodobacter capsulatus. Journal of Biological Inorganic Chemistry, 14 (3), 409-419. doi: 10.1007/s00775-008-0458-4

Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells

Potter, AJ, Kidd, SP, Edwards, JL, Falsetta, ML, Apicella, MA, Jennings, MP and McEwan, AG (2009). Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells. Journal of Infectious Diseases, 199 (2), 227-235. doi: 10.1086/595737

A mechanistic and electrochemical study of the interaction between dimethyl sulfide dehydrogenase and its electron transfer partner cytochrome c(2)

Creevey, Nicole L., McEwan, Alastair G. and Bernhardt, Paul V. (2008). A mechanistic and electrochemical study of the interaction between dimethyl sulfide dehydrogenase and its electron transfer partner cytochrome c(2). Journal of Biological Inorganic Chemistry, 13 (8), 1231-1238. doi: 10.1007/s00775-008-0406-3

Trade-off between iron uptake and protection against oxidative stress: Deletion of cueO promotes uropathogenic Escherichia coli virulence in a mouse model of urinary tract infection

Tree, Jai J., Ulett, Glen C., Ong, Cheryl-Lynn Y., Trott, Darren J., McEwan, Alastair G. and Schembri, Mark A. (2008). Trade-off between iron uptake and protection against oxidative stress: Deletion of cueO promotes uropathogenic Escherichia coli virulence in a mouse model of urinary tract infection. Journal of Bacteriology, 190 (20), 6909-6912. doi: 10.1128/JB.00451-08

Metal binding specificity of the MntABC permease of Neisseria gonorrhoeae and its influence on bacterial growth and interaction with cervical epithelial cells

Lim, Karen H. L., Jones, Christopher E., vanden Hoven, Rachel N., Edwards, Jennifer L., Falsetta, Megan L., Apicella, Michael A., Jennings, Michael P. and McEwan, Alastair G. (2008). Metal binding specificity of the MntABC permease of Neisseria gonorrhoeae and its influence on bacterial growth and interaction with cervical epithelial cells. Infection and Immunity, 76 (8), 3569-3576. doi: 10.1128/IAI.01725-07

Functional analysis of the multi-copper oxidase from Legionella pneumophila

Huston, Wilhelmina M., Naylor, Jennifer, Cianciotto, Nicholas P., Jennings, Michael P. and McEwan, Alastair G. (2008). Functional analysis of the multi-copper oxidase from Legionella pneumophila. Microbes And Infection, 10 (5), 497-503. doi: 10.1016/j.micinf.2008.01.011

Thermodynamic characterization of the redox centers within dimethylsulfide dehydrogenase

Creevey, N.L., McEwan, A.G., Hanson, G.R. and Bernhardt, P.V. (2008). Thermodynamic characterization of the redox centers within dimethylsulfide dehydrogenase. Biochemistry, 47 (12), 3770-3776. doi: 10.1021/bi702444r

Bioenergetic Models for Acetate and Phosphate Transport in Bacteria Important in Enhanced Biological Phosphorus Removal

Burow, Luke C., Mabbett, Amanda N., McEwan, Alastair G., Bond, Philip L. and Blackall, Linda L. (2008). Bioenergetic Models for Acetate and Phosphate Transport in Bacteria Important in Enhanced Biological Phosphorus Removal. Environmental Microbiology, 10 (1), 87-98. doi: 10.1111/j.1462-2920.2007.01432.x

Identification of Type 3 Fimbriae in Uropathogenic Escherichia coli Reveals a Role in Biofilm Formation

Ong, C., Ulett, G., Mabbett, A., Beatson, S., Webb, R., Monaghan, W., Nimmo, G., Looke, D., McEwan, A. and Schembri, M. (2008). Identification of Type 3 Fimbriae in Uropathogenic Escherichia coli Reveals a Role in Biofilm Formation. Journal of Bacteriology, 190 (3), 1054-1063. doi: 10.1128/JB.01523-07

A pneumococcal MerR-like regulator and S-nitrosoglutathione reductase are required for systemic virulence

Stroeher, Uwe H., Kidd, Stephen P., Stafford, Sian L., Jennings, Michael P., Paton, James C. and McEwan, Alastair G. (2007). A pneumococcal MerR-like regulator and S-nitrosoglutathione reductase are required for systemic virulence. The Journal of Infectious Diseases, 196 (12), 1820-1826. doi: 10.1086/523107

Spectroscopic and kinetic studies of Y114F and W116F mutants of Me2SO reductase from Rhodobacter capsulatus

Cobb, N, Hemann, C, Polsinelli, GA, Ridge, JP, McEwan, AG and Hille, R (2007). Spectroscopic and kinetic studies of Y114F and W116F mutants of Me2SO reductase from Rhodobacter capsulatus. Journal of Biological Chemistry, 282 (49), 35519-35529. doi: 10.1074/jbc.M704458200

PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity

Badrick, Alison C., Hamilton, Amanda J., Bernhardt, Paul V., Jones, Christopher E., Kappler, Ulrike, Jennings, Michael P. and McEwan, Alastair G. (2007). PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity. FEBS Letters, 581 (24), 4663-4667. doi: 10.1016/j.febslet.2007.08.058

Glutathione-dependent alcohol dehydrogenase AdhC is required for Defense against nitrosative stress in Haemophilus influenzae

Kidd, Stephen P., Jiang, Donald, Jennings, Michael P. and McEwan, Alastair G. (2007). Glutathione-dependent alcohol dehydrogenase AdhC is required for Defense against nitrosative stress in Haemophilus influenzae. Infection And Immunity, 75 (9), 4506-4513. doi: 10.1128/IAI.00487-07

Proton motive force generation from stored polymers for the uptake of acetate under anaerobic conditions

Saunders, AM, Mabbett, AN, McEwan, AG and Blackall, LL (2007). Proton motive force generation from stored polymers for the uptake of acetate under anaerobic conditions. Fems Microbiology Letters, 274 (2), 245-251. doi: 10.1111/j.1574-6968.2007.00839.x

Visualisation of pyrite leaching by selected thermophilic archaea: nature of microorganism-ore interactions during bioleaching

Mikkelsen, D., Kappler, U., Webb, R. I., Rasch, R., McEwan, A. G. and Sly, L. I. (2007). Visualisation of pyrite leaching by selected thermophilic archaea: nature of microorganism-ore interactions during bioleaching. Hydrometallurgy, 88 (1-4), 143-153. doi: 10.1016/j.hydromet.2007.02.013

A multicopper oxidase is essential for manganese oxidation and laccase-like activity in Pedomicrobium sp ACM 3067

Ridge, Justin P., Lin, Marianne, Larsen, Eloise I., Fegan, Mark, McEwan, Alastair G. and Sly, Lindsay I. (2007). A multicopper oxidase is essential for manganese oxidation and laccase-like activity in Pedomicrobium sp ACM 3067. Environmental Microbiology, 9 (4), 944-953. doi: 10.1111/j.1462-2920.2006.01216.x

The multicopper oxidase (CueO) and cell aggregation in Escherichia coli

Tree, JJ, Ulett, GC, Hobman, JL, Constantinidou, C, Brown, NL, Kershaw, C, Schembri, MA, Jennings, MP and McEwan, AG (2007). The multicopper oxidase (CueO) and cell aggregation in Escherichia coli. Environmental Microbiology, 9 (8), 2110-2116. doi: 10.1111/j.1462-2920.2007.01320.x

Evidence for distinctive mechanisms of S-nitrosoglutathione metabolism by AdhC in two closely related species, Neisseria gonorrhoeae and Neisseria meningitidis

Potter, Adam J., Kidd, Stephen P., Jennings, Michael P. and McEwan, Alastair G. (2007). Evidence for distinctive mechanisms of S-nitrosoglutathione metabolism by AdhC in two closely related species, Neisseria gonorrhoeae and Neisseria meningitidis. Infection And Immunity, 75 (3), 1534-1536. doi: 10.1128/IAI.01634-06

Characterization of the OxyR regulon of Neisseria gonorrhoeae

Seib, KL, Wu, HJ, Srikhanta, YN, Edwards, JL, Falsetta, ML, Hamilton, AJ, Maguire, TL, Grimmond, SM, Apicella, MA, McEwan, AG and Jennings, MP (2007). Characterization of the OxyR regulon of Neisseria gonorrhoeae. Molecular Microbiology, 63 (1), 54-68. doi: 10.1111/j.1365-2958.2006.05478.x

Archaeal diversity in two thermophilic chalcopyrite bioleaching reactors

Mikkelsen, Deirdre, Kappler, Ulrike, McEwan, Alastair G. and Sly, Lindsay I. (2006). Archaeal diversity in two thermophilic chalcopyrite bioleaching reactors. Environmental Microbiology, 8 (11), 2050-2055. doi: 10.1111/j.1462-2920.2005.01115.x

Cross-talk towards the response regulator NtrC controlling nitrogen metabolism in Rhodobacter capsulatus

Drepper, T., Wiethaus, J., Giaourakis, D., Gross, S., Schubert, B., Vogt, M., Wiencek, Y., McEwan, A. G. and Masepohl, B. (2006). Cross-talk towards the response regulator NtrC controlling nitrogen metabolism in Rhodobacter capsulatus. Fems Microbiology Letters, 258 (2), 250-256. doi: 10.1111/j.1574-6968.2006.00228.x

Defenses against oxidative stress in Neisseria gonorrhoeae: A system tailored for a challenging environment

Seib, K. L., Wu, H. J., Kidd, S. P., Apicella, M. A., Jennings, M. P. and McEwan, A. G. (2006). Defenses against oxidative stress in Neisseria gonorrhoeae: A system tailored for a challenging environment. Microbiology And Molecular Biology Reviews, 70 (2), 344-361. doi: 10.1128/MMBR.00044-05

Direct electrochemically driven catalysis of bovine milk xanthine oxidase

Bernhardt, P. V., Honeychurch, M. J. and McEwan, A. G. (2006). Direct electrochemically driven catalysis of bovine milk xanthine oxidase. Electrochemistry Communications, 8 (2), 257-261. doi: 10.1016/j.elecom.2005.08.009

PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae

Wu, H. J., Seib, K. L., Srikhanta, Y. N., Kidd, S. P., Edwards, J. L., Maguire, T. L., Grimmond, S. M., Apicella, M. A., McEwan, A. G. and Jennings, M. P. (2006). PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae. Molecular Microbiology, 60 (2), 401-416. doi: 10.1111/j.1365-2958.2006.05079.x

Spectroscopic characterization of copper(II) binding to the immunosuppressive drug mycophenolic acid

Jones, C. E., Taylor, P. J., McEwan, A. G. and Hanson, G. R. (2006). Spectroscopic characterization of copper(II) binding to the immunosuppressive drug mycophenolic acid. Journal of The American Chemical Society, 128 (29), 9378-9386. doi: 10.1021/ja057651l

Azurin of pathogenic Neisseria spp. is involved in defense against hydrogen peroxide and survival within cervical epithelial cells

Wu, Hsing-Ju, Seib, Kate L., Edwards, Jennifer L., Apicella, Michael A., McEwan, Alastair G. and Jennings, Michael P. (2005). Azurin of pathogenic Neisseria spp. is involved in defense against hydrogen peroxide and survival within cervical epithelial cells. Infection And Immunity, 73 (12), 8444-8448. doi: 10.1128/IAI.73.12.8444-8448.2005

NmlR of Neisseria gonorrhoeae: a novel redox responsive transcription factor from the MerR family

Kidd, SP, Potter, AJ, Apicella, MA, Jennings, MP and McEwan, AG (2005). NmlR of Neisseria gonorrhoeae: a novel redox responsive transcription factor from the MerR family. Molecular Microbiology, 57 (6), 1676-1689. doi: 10.1111/j.1365-2958.2005.04773.x

Investigation of oxidative stress defenses of Neisseria gonorrhoeae by using a human polymorphonuclear leukocyte survival assay

Seib, Kate L., Simons, Mark P., Wu, Hsing-Ju, McEwan, Alastair G., Nauseef, William M., Apicella, Michael A. and Jennings, Michael P. (2005). Investigation of oxidative stress defenses of Neisseria gonorrhoeae by using a human polymorphonuclear leukocyte survival assay. Infection and Immunity, 73 (8), 5269-5272. doi: 10.1128/IAI.73.8.5269-5272.2005

A recombinant diheme SoxAX cytochrome - Implications for the relationship between EPR signals and modified heme-ligands

Kappler, Ulrike, Hanson, Graeme R., Jones, Alun and McEwan, Alastair G. (2005). A recombinant diheme SoxAX cytochrome - Implications for the relationship between EPR signals and modified heme-ligands. Febs Letters, 579 (11), 2491-2498. doi: 10.1016/j.febslet.2005.03.060

Copper sensitivity of cueO mutants of Escherichia coli K-12 and the biochemical suppression of this phenotype

Tree, J. J., Kidd, S. P., Jennings, M. P. and McEwan, A. G. (2005). Copper sensitivity of cueO mutants of Escherichia coli K-12 and the biochemical suppression of this phenotype. Biochemical And Biophysical Research Communications, 328 (4), 1205-1210. doi: 10.1016/j.bbrc.2005.01.084

Microbial dimethylsulfoxide and trimethylamine-N-oxide respiration

McCrindle, S. L., Kappler, U. and McEwan, A. G. (2005). Microbial dimethylsulfoxide and trimethylamine-N-oxide respiration. Advances In Microbial Physiology, Vol 50, 50, 147-198. doi: 10.1016/S0065-2911(05)50004-3

Respiratory gene clusters of Metallosphaera sedula - differential expression and transcriptional organization

Kappler, U., Sly, L. I. and McEwan, A. G. (2005). Respiratory gene clusters of Metallosphaera sedula - differential expression and transcriptional organization. Microbiology-sgm, 151 (Part 1), 35-43. doi: 10.1099/mic.0.27515-0

Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: Distinctive systems for different lifestyles

Seib, Kate L., Tseng, Hsing‐Ju, McEwan, Alastair G., Apicella, Michael A. and Jennings, Michael P. (2004). Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: Distinctive systems for different lifestyles. Journal of Infectious Diseases, 190 (1), 136-147. doi: 10.1086/421299

Cytochrome c(551) from Starkeya novella - Characterization, spectroscopic properties, and phylogeny of a diheme protein of the SoxAX family

Kappler, U., Aguey-Zinsou, K. F., Hanson, G. R., Bernhardt, P. V. and McEwan, A. G. (2004). Cytochrome c(551) from Starkeya novella - Characterization, spectroscopic properties, and phylogeny of a diheme protein of the SoxAX family. The Journal of Biological Chemistry, 279 (8), 6252-6260. doi: 10.1074/jbc.M310644200

Molecular analysis of the psa permease complex of Streptococcus pneumoniae

McAllister, Lauren J., Tseng, Hsing-Ju, Ogunniyi, A. David, Jennings, Michael P., McEwan, Alastair G. and Paton, James C. (2004). Molecular analysis of the psa permease complex of Streptococcus pneumoniae. Molecular Microbiology, 53 (3), 889-901. doi: 10.1111/j.1365-2958.2004.04164.x

Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa

Huston, W. M., Potter, A. J., Jennings, M. P., Rello, J., Hauser, A. R. and McEwan, A. G. (2004). Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa. Journal of Clinical Microbiology, 42 (6), 2806-2809. doi: 10.1128/JCM.42.6.2806-2809.2004

The critical role of tryptophan-116 in the catalytic cycle of dimethylsulfoxide reductase from Rhodobacter capsulatus

Ridge, J. P., Aguey-Zinsou, K. F., Bernhardt, P. V., Hanson, G. R. and McEwan, A. G. (2004). The critical role of tryptophan-116 in the catalytic cycle of dimethylsulfoxide reductase from Rhodobacter capsulatus. FEBS Letters, 563 (1-3), 197-202. doi: 10.1016/S0014-5793(04)00301-1

Identification and in vivo characterization of PpaA, a regulator of photosystem formation in Rhodobacter sphaeroides

Gomelsky, L., Sram, J., Moskvin, O. V., Horne, I. M., Dodd, H. N., Pemberton, J. M., McEwan, A. G., Kaplan, S. and Gomelsky, M. (2003). Identification and in vivo characterization of PpaA, a regulator of photosystem formation in Rhodobacter sphaeroides. Microbiology-sgm, 149 (2), 377-388. doi: 10.1099/mic.0.25972-0

A Sco homologue plays a role in defence against oxidative stress in pathogenic Neisseria

Seib, K. L., Jennings, M. P. and McEwan, A. G. (2003). A Sco homologue plays a role in defence against oxidative stress in pathogenic Neisseria. Febs Letters, 546 (2-3), 411-415. doi: 10.1016/S0014-5793(03)00632-X

Direct electrochemistry of a bacterial sulfite dehydrogenase

Aguey-Zinsou, Kondo-Francois, Bernhardt, Paul. V., Kappler, Ulrike and McEwan, Alastair G. (2003). Direct electrochemistry of a bacterial sulfite dehydrogenase. Journal of The American Chemical Society, 125 (2), 530-535. doi: 10.1021/ja028293e

OxyR acts as a repressor of catalase expression in Neisseria gonorrhoeae

Tseng, Hsing-Ju, McEwan, Alastair G., Apicella, Michael A. and Jennings, Michael P. (2003). OxyR acts as a repressor of catalase expression in Neisseria gonorrhoeae. Infection and Immunity, 71 (1), 550-556. doi: 10.1128/IAI.71.1.550-556.2003

The first non-turnover voltammetric response from a molybdenum enzyme: direct electroscopy of dimethylsulfoxide reductase from Rhodobacter capsulatus

Aguey, F. K., Bernhardt, P. V., McEwan, A. G. and Ridge, J. P. (2002). The first non-turnover voltammetric response from a molybdenum enzyme: direct electroscopy of dimethylsulfoxide reductase from Rhodobacter capsulatus. Journal of Biological Inorganic Chemistry, 7 (7-8), 879-883. doi: 10.1007/s00775-002-0374-y

The multicopper oxidase of Pseudomonas aeruginosa is a ferroxidase with a central role in iron acquisition

Huston, Wilhelmina M., Jennings, Michael P. and McEwan, Alastair G. (2002). The multicopper oxidase of Pseudomonas aeruginosa is a ferroxidase with a central role in iron acquisition. Molecular Microbiology, 45 (6), 1741-1750. doi: 10.1046/j.1365-2958.2002.03132.x

Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes

McDevitt, Christopher A., Hugenholtz, Philip, Hanson, Graeme R. and McEwan, Alastair G. (2002). Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes. Molecular Microbiology, 44 (6), 1575-1587. doi: 10.1046/j.1365-2958.2002.02978.x

PrrC from Rhodobacter sphaeroides, a homologue of eukaryotic Sco proteins, is a copper-binding protein and may have a thiol-disulfide oxidoreductase activity

McEwan, Alastair G., Lewin, Allison, Davy, Sharon L., Boetzel, Ruth, Leech, Andrew, Walker, Daniel, Wood, Tania and Moore, Geoffrey R. (2002). PrrC from Rhodobacter sphaeroides, a homologue of eukaryotic Sco proteins, is a copper-binding protein and may have a thiol-disulfide oxidoreductase activity. Febs Letters, 518 (1-3), 10-16. doi: 10.1016/S0014-5793(02)02532-2

Virulence of Streptococcus pneumoniae: PsaA mutants are hypersensitive to oxidative stress

Tseng, Hsing-Ju, McEwan, Alastair G., Paton, James C. and Jennings, Michael P. (2002). Virulence of Streptococcus pneumoniae: PsaA mutants are hypersensitive to oxidative stress. Infection And Immunity, 70 (3), 1635-1639. doi: 10.1128/IAI.70.3.1635-1639.2002

A system for the heterologous expression of complex redox proteins in Rhodobacter capsulatus: characterisation of recombinant sulphite : cytochrome c oxidoreductase from Starkeya novella

Kappler, U. and McEwan, A. G. (2002). A system for the heterologous expression of complex redox proteins in Rhodobacter capsulatus: characterisation of recombinant sulphite : cytochrome c oxidoreductase from Starkeya novella. Febs Letters, 529 (2-3), 208-214. doi: 10.1016/S0014-5793(02)03344-6

Characterization of redox centers in dimethyl sulfide dehydrogenase from Rhodovulum sulfidophilum

McDevitt, C. A., Hanson, G. R., Noble, C. J., Cheesman, M. R. and McEwan, A. G. (2002). Characterization of redox centers in dimethyl sulfide dehydrogenase from Rhodovulum sulfidophilum. Biochemistry, 41 (51), 15234-15244. doi: 10.1021/bi026221u

Control of dimethylsulfoxide reductase expression in Rhodobacter capsulatus: the role of carbon metabolites and the response regulators DorR and RegA

Kappler, U., Huston, W. M. and McEwan, A. G. (2002). Control of dimethylsulfoxide reductase expression in Rhodobacter capsulatus: the role of carbon metabolites and the response regulators DorR and RegA. Microbiology-sgm, 148 (2), 605-614. doi: 10.1099/00221287-148-2-605

Site-Directed Mutagenesis of Dimethyl Sulfoxide Reductase from Rhodobacter capsulatus: Characterization of a Y114 → F Mutant

Ridge, Justin P., Aguey, Kondo-Francois, Bernhardt, Paul V., Brereton, Ian M., Hanson, Graeme R. and McEwan, Alastair G. (2002). Site-Directed Mutagenesis of Dimethyl Sulfoxide Reductase from Rhodobacter capsulatus: Characterization of a Y114 → F Mutant. Biochemistry, 41 (52), 15762-15769. doi: 10.1021/bi0266582

The DMSO reductase family of microbial molybdenum enzymes; Molecular properties and role in the dissimilatory reduction of toxic elements

McEwan, A. G., Ridge, J. P., McDevitt, C. A. and Hugenholtz, P. (2002). The DMSO reductase family of microbial molybdenum enzymes; Molecular properties and role in the dissimilatory reduction of toxic elements. Geomicrobiology Journal, 19 (1), 3-21. doi: 10.1080/014904502317246138

Accumulation of manganese in Neisseria gonorrhoeae correlates with resistance to oxidative killing by superoxide anion and is independent of superoxide dismutase activity

Tseng, Hsing-Ju, Srikhanta, Yogitha, McEwan, Alastair G. and Jennings, Michael P. (2001). Accumulation of manganese in Neisseria gonorrhoeae correlates with resistance to oxidative killing by superoxide anion and is independent of superoxide dismutase activity. Molecular Microbiology, 40 (5), 1175-1186. doi: 10.1046/j.1365-2958.2001.02460.x

Active site heterogeneity in dimethyl sulfoxide reductase from Rhodobacter capsulatus revealed by raman spectroscopy

Bell, A. F., He, X., Ridge, J. P., Hanson, G. R., McEwan, A. G. and Tonge, P. J. (2001). Active site heterogeneity in dimethyl sulfoxide reductase from Rhodobacter capsulatus revealed by raman spectroscopy. Biochemistry, 40 (2), 440-448. doi: 10.1021/bi002065k

Molybdate-dependent expression of dimethylsulfoxide reductase in Rhodobacter capsulatus

Solomon, Peter S., Shaw, Anthony L., Young, Michael D., Leimkuhler, Silke, Hanson, Graeme R., Klipp, Werner and McEwan, Alastair G. (2000). Molybdate-dependent expression of dimethylsulfoxide reductase in Rhodobacter capsulatus. FEMS Microbiology Letters, 190 (2), 203-208. doi: 10.1016/S0378-1097(00)00336-0

Domain structure, oligomeric state, and mutational analysis of PpSR, the Rhodobacter sphaeroides repressor of photosystem gene expression

Gomelsky, Mark, Horne, Irene M., Lee, Hye-Joo, Pemberton, John M., McEwan, Alastair G. and Kaplan, Samuel (2000). Domain structure, oligomeric state, and mutational analysis of PpSR, the Rhodobacter sphaeroides repressor of photosystem gene expression. Journal of Bacteriology, 182 (8), 2253-2261. doi: 10.1128/JB.182.8.2253-2261.2000

Aerobic nitrate respiration in a nitrite-oxidising bioreactor

McDevitt, C., Burrell, P., Blackall, L. L. and McEwan, A. G. (2000). Aerobic nitrate respiration in a nitrite-oxidising bioreactor. FEMS Microbiology Letters, 184 (1), 113-118. doi: 10.1111/j.1574-6968.2000.tb09000.x

Sulfite : Cytochrome c oxidoreductase from Thiobacillus novellus - Purification, characterization, and molecular biology of a heterodimeric member of the sulfite oxidase family

Kappler, U, Bennett, B, Rethmeier, J, Schwarz, G, Deutzmann, R, McEwan, AG and Dahl, C (2000). Sulfite : Cytochrome c oxidoreductase from Thiobacillus novellus - Purification, characterization, and molecular biology of a heterodimeric member of the sulfite oxidase family. Journal of Biological Chemistry, 275 (18), 13202-13212. doi: 10.1074/jbc.275.18.13202

Characterization of DorC from Rhodobacter capsulatus, a c-type Cytochrome Involved in Electron Transfer to Dimethylsulfoxide Reductase

Shaw, Anthony L., Hochkoeppler, Alejandro, Bonora, Patrizia, Zannoni, Davide, Hanson, Graeme R. and Mcewan, Alastair G. (1999). Characterization of DorC from Rhodobacter capsulatus, a c-type Cytochrome Involved in Electron Transfer to Dimethylsulfoxide Reductase. Communication, 274 (15), 9911-9914. doi: 10.1074/jbc.274.15.9911

Characterization of a molybdenum cofactor biosynthetic gene cluster in Rhodobacter capsulatus which is specific for the biogenesis of dimethylsulfoxide reductase

Solomon, P. S., Shaw, A. L., Lane, I., Hanson, G. R., Palmer, T. and McEwan, A. G. (1999). Characterization of a molybdenum cofactor biosynthetic gene cluster in Rhodobacter capsulatus which is specific for the biogenesis of dimethylsulfoxide reductase. Microbiology, 145 (6), 1421-1429. doi: 10.1099/13500872-145-6-1421

Manganese(II) adsorption and oxidation by whole cells and a membrane fraction of Pedomicrobium sp. ACM 3067

Larsen, E. I., Sly, L. I. and McEwan, A. G. (1999). Manganese(II) adsorption and oxidation by whole cells and a membrane fraction of Pedomicrobium sp. ACM 3067. Archives of Microbiology, 171 (4), 257-264. doi: 10.1007/s002030050708

Mutational analysis of the dimethysulfoxide respiratory (dor) operon of Rhodobacter capsulatus

Shaw, A., Leimkuhler, S., Klipp, W., Hanson, G. R. and Mcewan, A. G. (1999). Mutational analysis of the dimethysulfoxide respiratory (dor) operon of Rhodobacter capsulatus. Microbiology, 145 (6), 1409-1420. doi: 10.1099/13500872-145-6-1409

Reactions of dimethylsulfoxide reductase from Rhodobacter capsulatus with dimethyl sulfide and dimethyl sulfoxide: Complexities revealed by conventional and stopped-flow spectrophotometry

Adams, B., Smith, A. T., Bailey, S., McEwan, A. G. and Bray, R. C. (1999). Reactions of dimethylsulfoxide reductase from Rhodobacter capsulatus with dimethyl sulfide and dimethyl sulfoxide: Complexities revealed by conventional and stopped-flow spectrophotometry. Biochemistry, 38 (26), 8501-8511. doi: 10.1021/bi9902034

Dimethylsulfoxide enhances phototrophic growth of Rhodobacter sphaeroides in blue light

Horne I. and McEwan A.G. (1998). Dimethylsulfoxide enhances phototrophic growth of Rhodobacter sphaeroides in blue light. FEMS Microbiology Letters, 168 (2), 283-288. doi: 10.1016/S0378-1097(98)00453-4

Xanthine dehydrogenase from the phototrophic purple bacterium Rhodobacter capsulatus is more similar to its eukaryotic counterparts than to prokaryotic molybdenum enzymes

Leimkühler, Silke, Kern, Monika, Solomon, Peter S., McEwan, Alastair G., Schwarz, Günter, Mendel, Ralf R. and Klipp, Werner (1998). Xanthine dehydrogenase from the phototrophic purple bacterium Rhodobacter capsulatus is more similar to its eukaryotic counterparts than to prokaryotic molybdenum enzymes. Molecular Microbiology, 27 (4), 853-869. doi: 10.1046/j.1365-2958.1998.00733.x

Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species

Hanlon, Steven P., Graham, Daniel L., Hogan, Philip J., Holt, Robert A., Reeve, Christopher D., Shaw, Anthony L. and McEwan, Alastair G. (1998). Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species. Microbiology, 144 (8), 2247-2253. doi: 10.1099/00221287-144-8-2247

Manganous ions suppress photosynthesis gene expression in Rhodobacter sphaeroides

Horne I.M., Pemberton J.M. and McEwan A.G. (1998). Manganous ions suppress photosynthesis gene expression in Rhodobacter sphaeroides. Microbiology, 144 (8), 2255-2261. doi: 10.1099/00221287-144-8-2255

Regulation of photosynthetic gene expression in purple bacteria

Pemberton J.M., Horne I.M. and McEwan A.G. (1998). Regulation of photosynthetic gene expression in purple bacteria. Microbiology, 144 (2), 267-278. doi: 10.1099/00221287-144-2-267

Stopped-flow studies on dimethylsulphoxide reductase from Rhodobacter capsulatus: Kinetic competence of the dimethylsulphide-reduced intermediate

Smith, Andrew T., Bray, Robert C., McEwan, Alastair G., McAlpine, Alan S. and Bailey, Sue (1998). Stopped-flow studies on dimethylsulphoxide reductase from Rhodobacter capsulatus: Kinetic competence of the dimethylsulphide-reduced intermediate. Biochemical Society Transactions, 26 (3), S211-S211. doi: 10.1042/bst026s211

The high resolution crystal structure of DMSO reductase in complex with DMSO

McAlpine A.S., McEwan A.G. and Bailey S. (1998). The high resolution crystal structure of DMSO reductase in complex with DMSO. Journal of Molecular Biology, 275 (4), 613-623. doi: 10.1006/jmbi.1997.1513

Molybdenum active centre of DMSO reductase from Rhodobacter capsulatus: Crystal structure of the oxidised enzyme at 1.82-Å resolution and the dithionite-reduced enzyme at 2.8-Å resolution

McAlpine, A. S., McEwan, A. G., Shaw, A. L. and Bailey, S. (1997). Molybdenum active centre of DMSO reductase from Rhodobacter capsulatus: Crystal structure of the oxidised enzyme at 1.82-Å resolution and the dithionite-reduced enzyme at 2.8-Å resolution. Journal of Biological Inorganic Chemistry, 2 (6), 690-701. doi: 10.1007/s007750050185

X-ray absorption spectroscopy of dimethylsulfoxide reductase from Rhodobacter capsulatus

Baugh, Philippa E., Garner, C.D., Charnock, John M., Collison, David, Davies, E. Stephen, McAlpine, Alan S., Bailey, S., Lane, Ian, Hanson, Graeme R. and McEwan, Alastair G. (1997). X-ray absorption spectroscopy of dimethylsulfoxide reductase from Rhodobacter capsulatus. Journal of Biological Inorganic Chemistry, 2 (5), 634-643. doi: 10.1007/s007750050178

Characterisation of the Pterin Molybdenum Cofactor in Dimethylsulfoxide Reductase of Rhodobacter capsulatus and the periplasmic Nitrate Reductase of Paracoccus denitrificans

Solomon, Peter S., Lane, Ian, Hanson, Graeme R. and McEwan, Alastair G. (1997). Characterisation of the Pterin Molybdenum Cofactor in Dimethylsulfoxide Reductase of Rhodobacter capsulatus and the periplasmic Nitrate Reductase of Paracoccus denitrificans. European Journal of Biochemistry, 246 (1), 200-203. doi: 10.1111/j.1432-1033.1997.t01-2-00200.x

Cloning and sequence analysis of the dimethylsulfoxide reductase structural gene from Rhodobacter capsulatus

Shaw, A. L., Hanson, G. R. and McEwan, A. G. (1996). Cloning and sequence analysis of the dimethylsulfoxide reductase structural gene from Rhodobacter capsulatus. Biochimica Et Biophysica Acta-bioenergetics, 1276 (3), 176-180. doi: 10.1016/0005-2728(96)00092-8

The influence of chelating agents upon the dissimilatory reduction of Fe(III) by Shewanella putrefaciens. Part 2. Oxo- and hydroxo-bridged polynuclear Fe(III) complexes

Dobbin, Paul S., Requena Burmeister, Laura M., Heath, Sarah L., Powell, Anne K., McEwan, Alastair G. and Richardson, David J. (1996). The influence of chelating agents upon the dissimilatory reduction of Fe(III) by Shewanella putrefaciens. Part 2. Oxo- and hydroxo-bridged polynuclear Fe(III) complexes. BioMetals, 9 (3), 291-301. doi: 10.1007/BF00817930

Isolation, characterisation and expression of the bacterioferritin gene of Rhodobacter capsulatus

Penfold, Christopher N., Ringeling, Patricia L., Davy, Sharon L., Moore, Geoffrey R., McEwan, Alastair G. and Spiro, Stephen (1996). Isolation, characterisation and expression of the bacterioferritin gene of Rhodobacter capsulatus. FEMS Microbiology Letters, 139 (2-3), 143-148. doi: 10.1016/0378-1097(96)00133-4

Dimethylsulfide: Acceptor oxidoreductase from Rhodobacter sulfidophilus - The purified enzyme contains b-type haem and a pterin molybdenum cofactor

Hanlon, Steven P., Toh, Tze-Hsien, Solomon, Peter S., Holt, Robert A. and McEwan, Alastair G. (1996). Dimethylsulfide: Acceptor oxidoreductase from Rhodobacter sulfidophilus - The purified enzyme contains b-type haem and a pterin molybdenum cofactor. European Journal of Biochemistry, 239 (2), 391-396. doi: 10.1111/j.1432-1033.1996.0391u.x

Dissimilatory iron(III) reduction by Rhodobacter capsulatus

Dobbin, Paul S., Warren, Louise H., Cook, Nicola J., McEwan, Alastair G., Powell, Anne K. and Richardson, David J. (1996). Dissimilatory iron(III) reduction by Rhodobacter capsulatus. Microbiology, 142 (4), 765-774. doi: 10.1099/00221287-142-4-765

Photosynthesis gene expression in Rhodobacter sphaeroides is regulated by redox changes which are linked to electron transport

Horne, Irene M., Pemberton, John M. and McEwan, Alastair G. (1996). Photosynthesis gene expression in Rhodobacter sphaeroides is regulated by redox changes which are linked to electron transport. Microbiology, 142 (10), 2831-2838. doi: 10.1099/13500872-142-10-2831

Preliminary crystallographic studies of dimethylsulfoxide reductase from Rhodobacter capsulatus

Bailey, S., Mcalpine, A. S., Duke, E. M.H., Benson, N. and Mcewan, A. G. (1996). Preliminary crystallographic studies of dimethylsulfoxide reductase from Rhodobacter capsulatus. Acta Crystallographica Section D: Biological Crystallography, 52 (1), 194-196. doi: 10.1107/S0907444995007712

Phenotypic characterisation and genetic complementation of dimethylsulfoxide respiratory mutants of Rhodobacter sphaeroides and Rhodobacter capsulatus

Bonnett, Tracey C., Cobine, Paul, Sockett, R.Elizabeth and McEwan, Alastair G. (1995). Phenotypic characterisation and genetic complementation of dimethylsulfoxide respiratory mutants of Rhodobacter sphaeroides and Rhodobacter capsulatus. FEMS Microbiology Letters, 133 (1-2), 163-168. doi: 10.1016/0378-1097(95)00358-C

The influence of chelating agents upon the dissimilatory reduction of Fe(III) by Shewanella putrefaciens

Dobbin, Paul S., Powell, Anne K., McEwan, Alastair G. and Richardson, David J. (1995). The influence of chelating agents upon the dissimilatory reduction of Fe(III) by Shewanella putrefaciens. Biometals, 8 (2), 163-173. doi: 10.1007/BF00142016

Determination of Dimethyl Sulfoxide in Aqueous Solution by an Enzyme-Linked Method

Hatton, A. D., Malin, G., McEwan, A. G., Liss, P. S. and McEwan, A. G. (1994). Determination of Dimethyl Sulfoxide in Aqueous Solution by an Enzyme-Linked Method. Analytical Chemistry, 66 (22), 4093-4096. doi: 10.1021/ac00094a036

Identification of a periplasmic dimethylsulphoxide reductase in Hyphomicrobium EG grown under chemolithoheterotrophic conditions with dimethylsulphoxide as carbon source

Hatton, Angela D., Malin, Gill and McEwan, Alastair G. (1994). Identification of a periplasmic dimethylsulphoxide reductase in Hyphomicrobium EG grown under chemolithoheterotrophic conditions with dimethylsulphoxide as carbon source. Archives of Microbiology, 162 (1-2), 148-150. doi: 10.1007/bf00264389

Iron metabolism in Rhodobacter capsulatus Characterisation of bacterioferritin and formation of non‐haem iron particles in intact cells

RINGELING, Patricia L., DAVY, Sharon L., MONKARA, Fayez A., HUNT, Colette, DICKSON, Dominic P. E., McEWAN, Alastair G. and MOORE, Geoffrey R. (1994). Iron metabolism in Rhodobacter capsulatus Characterisation of bacterioferritin and formation of non‐haem iron particles in intact cells. European Journal of Biochemistry, 223 (3), 847-855. doi: 10.1111/j.1432-1033.1994.tb19061.x

Isolation and characterization of a strain of Rhodobacter sulfidophilus: A bacterium which grows autotrophically with dimethylsulphide as electron donor

Hanlon S.P., Holt R.A., Moore G.R. and McEwan A.G. (1994). Isolation and characterization of a strain of Rhodobacter sulfidophilus: A bacterium which grows autotrophically with dimethylsulphide as electron donor. Microbiology, 140 (8), 1953-1958. doi: 10.1099/13500872-140-8-1953

Multiple States of the Molybdenum Centre of Dimethylsulphoxide Reductase from Rhodobacter Capsulatus Revealed by EPR Spectroscopy

Bennett, Brian, Benson, Neil, McEwan, Alastair G. and Bray, Robert C. (1994). Multiple States of the Molybdenum Centre of Dimethylsulphoxide Reductase from Rhodobacter Capsulatus Revealed by EPR Spectroscopy. European Journal of Biochemistry, 225 (1), 321-331. doi: 10.1111/j.1432-1033.1994.00321.x

Photosynthetic electron transport and anaerobic metabolism in purple non-sulfur phototrophic bacteria

McEwan A.G. (1994). Photosynthetic electron transport and anaerobic metabolism in purple non-sulfur phototrophic bacteria. Antonie van Leeuwenhoek, 66 (1-3), 151-164. doi: 10.1007/BF00871637

Proton-Translocating NAD(P)-H Transhydrogenase and NADH Dehydrogenase in Photosynthetic Membranes

Jackson, J. Baz and McEwan, Alastair G. (1994). Proton-Translocating NAD(P)-H Transhydrogenase and NADH Dehydrogenase in Photosynthetic Membranes. Advances in Molecular and Cell Biology, 10 (C), 253-286. doi: 10.1016/S1569-2558(08)60399-9

Detection of c-type cytochromes using enhanced chemiluminescence

Vargas, C., McEwan, A. G. and Downie, J. A. (1993). Detection of c-type cytochromes using enhanced chemiluminescence. Analytical Biochemistry, 209 (2), 323-326. doi: 10.1006/abio.1993.1127

Membrane-associated NADH dehydrogenase activities in Rhodobacter capsulatus: Purification of a dihydrolipoyl dehydrogenase

Berks, B. C., McEwan, A. G. and Ferguson, S. J. (1993). Membrane-associated NADH dehydrogenase activities in Rhodobacter capsulatus: Purification of a dihydrolipoyl dehydrogenase. Journal of General Microbiology, 139 (8), 1841-1851. doi: 10.1099/00221287-139-8-1841

The 44-kDa c-type cytochrome induced in Rhodobacter capsulatus during growth with dimethylsulphoxide as an electron acceptor is a cytochrome c peroxidase

Hanlon, Steven P., Holt, Robert A. and McEwan, Alastair G. (1992). The 44-kDa c-type cytochrome induced in Rhodobacter capsulatus during growth with dimethylsulphoxide as an electron acceptor is a cytochrome c peroxidase. FEMS Microbiology Letters, 97 (3), 283-287. doi: 10.1016/0378-1097(92)90349-S

Detection of the optical bands of molybdenum(V) in DMSO reductase (Rhodobacter capsulatus ) by low-temperature MCD spectroscopy

Benson, Neil, Farrar, Jaqui A., McEwan, Alastair G. and Thomson, Andrew J. (1992). Detection of the optical bands of molybdenum(V) in DMSO reductase (Rhodobacter capsulatus ) by low-temperature MCD spectroscopy. FEBS Letters, 307 (2), 169-172. doi: 10.1016/0014-5793(92)80760-e

Spectroscopic studies of Rhodobacter capsulatus cytochrome c′ in the isolated state and in intact cells

Monkara, Fayez, Bingham, Stephen J., Kadir, Fahmi H.A., McEwan, Alastair G., Thomson, Andrew J., Thurgood, Andrew G.P. and Moore, Geoffrey R. (1992). Spectroscopic studies of Rhodobacter capsulatus cytochrome c′ in the isolated state and in intact cells. BBA - Bioenergetics, 1100 (2), 184-188. doi: 10.1016/0005-2728(92)90080-L

Cytochrome c2 is essential for electron transfer to nitrous oxide reductase from physiological substrates in Rhodobacter capsulatus and can act as an electron donor to the reductase in vitro Correlation with photoinhibition studies

RICHARDSON, David J., BELL, Louise C., McEWAN, Alastair G., JACKSON, J. Baz and FERGUSON, Stuart J. (1991). Cytochrome c2 is essential for electron transfer to nitrous oxide reductase from physiological substrates in Rhodobacter capsulatus and can act as an electron donor to the reductase in vitro Correlation with photoinhibition studies. European Journal of Biochemistry, 199 (3), 677-683. doi: 10.1111/j.1432-1033.1991.tb16170.x

Purification and properties of dimethyl sulphoxide reductase from Rhodobacter capsulatus. A periplasmic molybdoenzyme

McEwan, A. G., Ferguson, S. J. and Jackson, J. B. (1991). Purification and properties of dimethyl sulphoxide reductase from Rhodobacter capsulatus. A periplasmic molybdoenzyme. Biochemical Journal, 274 (1), 305-307. doi: 10.1042/bj2740305

The role of c-type cytochromes in the photosynthetic electron transport pathway of Rhodobacter capsulatus

Jones, M. R., McEwan, A. G. and Jackson, J. B. (1990). The role of c-type cytochromes in the photosynthetic electron transport pathway of Rhodobacter capsulatus. BBA - Bioenergetics, 1019 (1), 59-66. doi: 10.1016/0005-2728(90)90124-M

Rhodobacter capsulatus strain BK5 possesses a membrane bound respiratory nitrate reductase rather than the periplasmic enzyme found in other strains

Ballard, Anna L., McEwan, Alastair G., Richardson, David J., Jackson, J.Baz and Ferguson, Stuart J. (1990). Rhodobacter capsulatus strain BK5 possesses a membrane bound respiratory nitrate reductase rather than the periplasmic enzyme found in other strains. Archives of Microbiology, 154 (3), 301-303. doi: 10.1007/BF00248971

In vivo redox poising of the cyclic electron transport system of Rhodobacter capsulatus and the effects of the auxiliary oxidants, nitrate, nitrous oxide and trimethylamine N-oxide, as revealed by multiple short flash excitation

Jones, M. R., Richardson, D. J., McEwan, A. G., Ferguson, S. J. and Jackson, J. B. (1990). In vivo redox poising of the cyclic electron transport system of Rhodobacter capsulatus and the effects of the auxiliary oxidants, nitrate, nitrous oxide and trimethylamine N-oxide, as revealed by multiple short flash excitation. BBA - Bioenergetics, 1017 (3), 209-216. doi: 10.1016/0005-2728(90)90186-8

The identification of cytochromes involved in the transfer of electrons to the periplasmic NO−3 reductase of Rhodobacter capsulatus and resolution of a soluble NO−3 ‐reductase − cytochrome‐c552 redox complex

RICHARDSON, David J., McEWAN, Alastair G., PAGE, M. Dudley, JACKSON, J. Baz and FERGUSON, Stuart J. (1990). The identification of cytochromes involved in the transfer of electrons to the periplasmic NO−3 reductase of Rhodobacter capsulatus and resolution of a soluble NO−3 ‐reductase − cytochrome‐c552 redox complex. European Journal of Biochemistry, 194 (1), 263-270. doi: 10.1111/j.1432-1033.1990.tb19452.x

Synthesis of Rhodobacter sphaeroides cytochrome c2 in Escherichia coli

McEwan, Alastair G., Kaplan, Samuel and Donohue, Timothy J. (1989). Synthesis of Rhodobacter sphaeroides cytochrome c2 in Escherichia coli. FEMS Microbiology Letters, 59 (3), 253-258. doi: 10.1016/0378-1097(89)90427-8

Electron transport pathways to nitrous oxide in Rhodobacter species

RICHARDSON, David J., McEWAN, Alastair G., JACKSON, J. Baz and FERGUSON, Stuart J. (1989). Electron transport pathways to nitrous oxide in Rhodobacter species. European Journal of Biochemistry, 185 (3), 659-669. doi: 10.1111/j.1432-1033.1989.tb15163.x

Expression of the Rhodobacter sphaeroides cytochrome c2 structural gene

Brandner, J. P., McEwan, A. G., Kaplan, S. and Donohue, T. J. (1989). Expression of the Rhodobacter sphaeroides cytochrome c2 structural gene. Journal of bacteriology, 171 (1), 360-368. doi: 10.1128/jb.171.1.360-368.1989

Identification of cytochromes involved in electron transport to trimethylamine N-oxide/dimethylsulphoxide reductase in Rhodobacter capsulatus

McEwan, Alastair G., Richardson, David J., Hudig, Hendrik, Ferguson, Stuart J. and Jackson, J. Barry (1989). Identification of cytochromes involved in electron transport to trimethylamine N-oxide/dimethylsulphoxide reductase in Rhodobacter capsulatus. BBA - Bioenergetics, 973 (2), 308-314. doi: 10.1016/S0005-2728(89)80437-2

Synthesis of Rhodobacter sphaeroides cytochrome c2 in Escherichia coli

McEwan, Alastair G., Kaplan, Samuel and Donohue, Timothy J. (1989). Synthesis of Rhodobacter sphaeroides cytochrome c2 in Escherichia coli. FEMS Microbiology Letters, 59 (3), 253-258. doi: 10.1111/j.1574-6968.1989.tb03120.x

The Role of Auxiliary Oxidants in Maintaining Redox Balance During Phototrophic Growth of Rhodobacter-Capsulatus On Propionate or Butyrate

Richardson, DJ, King, GF, Kelly, DJ, McEwan, AG, Ferguson, SJ and Jackson, JB (1988). The Role of Auxiliary Oxidants in Maintaining Redox Balance During Phototrophic Growth of Rhodobacter-Capsulatus On Propionate or Butyrate. Archives of Microbiology, 150 (2), 131-137. doi: 10.1007/BF00425152

Phenotypic and Genetic Characterization of Cytochrome c2Deficient Mutants of Rhodobacter sphaeroides

Donohue, Timothy J., McEwan, Alastair G., Doren, Steven Van, Crofts, Antony R. and Kaplan, Samuel (1988). Phenotypic and Genetic Characterization of Cytochrome c2Deficient Mutants of Rhodobacter sphaeroides. Biochemistry, 27 (6), 1918-1925. doi: 10.1021/bi00406a018

The periplasmic nitrate reductase and trimethylamine-N-oxide reductase of the photosynthetic bacterium Rhodobacter capsulatus

McEwan, A. G., Richardson, D. J., Jackson, J. B. and Ferguson, S. J. (1988). The periplasmic nitrate reductase and trimethylamine-N-oxide reductase of the photosynthetic bacterium Rhodobacter capsulatus. Biochemical Society Transactions, 16 (2), 182-183. doi: 10.1042/bst0160182

The periplasmic nitrate reductase of Rhodobacter capsulatus; purification, characterisation and distinction from a single reductase for trimethylamine-N-oxide, dimethylsulphoxide and chlorate

McEwan, A. G., Wetzstein, H. G., Meyer, O., Jackson, J. B. and Ferguson, S. J. (1987). The periplasmic nitrate reductase of Rhodobacter capsulatus; purification, characterisation and distinction from a single reductase for trimethylamine-N-oxide, dimethylsulphoxide and chlorate. Archives of Microbiology, 147 (4), 340-345. doi: 10.1007/BF00406130

Anaerobic respiration in the Rhodospirillaceae: characterisation of pathways and evaluation of roles in redox balancing during photosynthesis

Ferguson, Stuart J., Jackson, J.Barry and McEwan, Alastair G. (1987). Anaerobic respiration in the Rhodospirillaceae: characterisation of pathways and evaluation of roles in redox balancing during photosynthesis. FEMS Microbiology Letters, 46 (2), 117-143. doi: 10.1016/0378-1097(87)90060-7

Cloning, DNA sequence, and expression of the Rhodobacter sphaeroides cytochrome c2 gene

Donohue, T. J., McEwan, A. G. and Kaplan, S. (1986). Cloning, DNA sequence, and expression of the Rhodobacter sphaeroides cytochrome c2 gene. Journal of Bacteriology, 168 (2), 962-972. doi: 10.1128/jb.168.2.962-972.1986

Nitrous oxide reduction by members of the family Rhodospirillaceae and the nitrous oxide reductase of Rhodopseudomonas capsulata

McEwan, A. G., Greenfield, A. J., Wetzstein, H. G., Jackson, J. B. and Ferguson, S. J. (1985). Nitrous oxide reduction by members of the family Rhodospirillaceae and the nitrous oxide reductase of Rhodopseudomonas capsulata. Journal of Bacteriology, 164 (2), 823-830.

The role of auxiliary oxidants in the maintenance of a balanced redox poise for photosynthesis in bacteria

McEwan, A. G., Cotton, N. P.J., Ferguson, S. J. and Jackson, J. B. (1985). The role of auxiliary oxidants in the maintenance of a balanced redox poise for photosynthesis in bacteria. BBA - Bioenergetics, 810 (2), 140-147. doi: 10.1016/0005-2728(85)90129-X

The activities of two pathways of nitrate reduction in Rhodopseudomonas capsulata

Alef, Kassem, Jackson, J. Barry, McEwan, Alastair G. and Ferguson, Stuart J. (1985). The activities of two pathways of nitrate reduction in Rhodopseudomonas capsulata. Archives of Microbiology, 142 (4), 403-408. doi: 10.1007/bf00491912

Periplasmic location of the terminal reductase in trimethylamine N-oxide and dimethylsulphoxide respiration in the photosynthetic bacterium Rhodopseudomonas capsulata

McEwan, A. G., Wetzstein, H. G., Ferguson, S. J. and Jackson, J. B. (1985). Periplasmic location of the terminal reductase in trimethylamine N-oxide and dimethylsulphoxide respiration in the photosynthetic bacterium Rhodopseudomonas capsulata. BBA - Bioenergetics, 806 (3), 410-417. doi: 10.1016/0005-2728(85)90248-8

Rationalization of properties of nitrate reductases in Rhodopseudomonas capsulata

McEwan, Alastair G., Jackson, J. Barry and Ferguson, Stuart J. (1984). Rationalization of properties of nitrate reductases in Rhodopseudomonas capsulata. Archives of Microbiology, 137 (4), 344-349. doi: 10.1007/bf00410732

Electron flow to dimethylsulphoxide or trimethylamine-N-oxide generates a membrane potential in Rhodopseudomonas capsulata

McEwan, Alastair G., Ferguson, Stuart J. and Jackson, J. Barry (1983). Electron flow to dimethylsulphoxide or trimethylamine-N-oxide generates a membrane potential in Rhodopseudomonas capsulata. Archives of Microbiology, 136 (4), 300-305. doi: 10.1007/bf00425221

A nitrate reductase activity in Rhodopseudomonas capsulata linked to electron transfer and generation of a membrane potential

McEwan, Alastair G., George, Christina L., Ferguson, Stuart J. and Jackson, J.Barry (1982). A nitrate reductase activity in Rhodopseudomonas capsulata linked to electron transfer and generation of a membrane potential. FEBS Letters, 150 (2), 277-280. doi: 10.1016/0014-5793(82)80751-5

Availability and Utility of Functional Imaging (FI) and Peptide Receptor Radionuclide Therapy (PRRT) in the CommNETS Collaboration (Australia, Canada and New Zealand)

Chan, B. A., Sim, H-W., Ravikumar, A., Bailey, D., Chan, D., Lawrence, B., McEwan, A., Pavlakis, N., Segelov, E., Singh, S., Roach, P. and Wyld, D. (2016). Availability and Utility of Functional Imaging (FI) and Peptide Receptor Radionuclide Therapy (PRRT) in the CommNETS Collaboration (Australia, Canada and New Zealand). Oxford, United Kingdom: Oxford University Press.

Is anaerobic respiration central to the ability of Haemophilus influenzae to colonize the human host?

Othman, Dk Seti Maimonah Pg, McEwan, Alastair G. and Kappler, Ulrike (2011). Is anaerobic respiration central to the ability of Haemophilus influenzae to colonize the human host?. BacPath 11: Molecular Analysis of Bacterial Pathogens, Wyong, New South Wales, 25 - 28 September 2011.

Application of CW and pulsed EPR, MoSophe, and DFT calculations in unravelling the electronic structure of the molybdenum(V) centre in dimethylsulfoxide reductase

Noble, C. J., Drew, S. C., Lane, I., Benson, S., McEwan, A. G., Young, C. G. and Hanson, G. R. (2007). Application of CW and pulsed EPR, MoSophe, and DFT calculations in unravelling the electronic structure of the molybdenum(V) centre in dimethylsulfoxide reductase. IC07 - Conference of the Inorganic Chemistry Division - Royal Australian Chemical Institute, Hobart, Australia, 4-8 February 2007.

A multi-copper oxidase is essential for manganese oxidation and Laccase-like activity in Pedomicrobium sp. ACM 3067

Ridge, J. P., Lin, M., Larsen, E., Fegan, M., McEwan, A. G. and Sly, L. I. (2006). A multi-copper oxidase is essential for manganese oxidation and Laccase-like activity in Pedomicrobium sp. ACM 3067. ASM 2006, Gold Coast, 2-6 July, 2006.

Application of CW and pulsed EPR, MoSophe and DFT calculations in unravelling the electron structure of the molybdenum(V) centre in dimethylsulfoxide reductase

Noble, C. J., Drew, S., Lane, I., Benson, S., McEwan, A. G. and Hanson, G. R. (2006). Application of CW and pulsed EPR, MoSophe and DFT calculations in unravelling the electron structure of the molybdenum(V) centre in dimethylsulfoxide reductase. Sendai-Berlin-Novosibirsk Seminar on Advanced EPR, Novosibirsk, Russia, 28-31 August, 2006.

EPR Studies of Dimethylsulfoxide Reductase: Mo(V) Species and Sulfur Centered Radicals - their Role in Catalysis

Lane, I., Noble, C. J., McEwan, A. G. and Hanson, G. R. (2006). EPR Studies of Dimethylsulfoxide Reductase: Mo(V) Species and Sulfur Centered Radicals - their Role in Catalysis. 48th Rocky Mountain Conference on Analytical Chemistry, Beaver Run Resort & Conference Center, Breckenridge, Colorado, USA, 23-27 July 2006. not found: not found.

EPR Studies of Sulfur Centered Radicals and the Low-g Type-I Mo(V) Species in Dimtheylsulfoxide reductase Implications for Catalysis and Electron Transfer

Lane, I., Drew, S. C., Noble, C. J., McEwan, A. G., Pilbrow, J. R. and Hanson, G. R. (2006). EPR Studies of Sulfur Centered Radicals and the Low-g Type-I Mo(V) Species in Dimtheylsulfoxide reductase Implications for Catalysis and Electron Transfer. Australian and New Zealand Magnetic Resonance Society, ANZMAG-2006, Murramarang National Park, 13-16 February 2006. ANZMAG.

Heavy metal ions and nanobiotechnology

Mabbett, A. N., Pioch, K. A., Webb, R. I. and McEwan, A. G. (2006). Heavy metal ions and nanobiotechnology. ASM 2006, Gold Coast, 2-6 July, 2006.

Cytochrome c551 from Starkeya novella - characterization, spectroscopic properties and phylogeny of a diheme protein of the SoxAX family

Kappler, U., Aguey, F.K., Hanson, G. R., Bernhardt, P. V. and McEwan, A. G. (2004). Cytochrome c551 from Starkeya novella - characterization, spectroscopic properties and phylogeny of a diheme protein of the SoxAX family. VAAM (Germany Microbiology Society) Meeting, Braunschweig, 28-31 March, 2004.

Development of molecular methods for monitoring thermophilic chalcopyrite bioleaching cultures

Mikkelsen, D., Kappler, U., McEwan, A. and Sly, L. (2004). Development of molecular methods for monitoring thermophilic chalcopyrite bioleaching cultures. Australian Society for Microbiology (ASM) Annual Scientific Meeting & Exhibition, Sydney, Australia, 26th Sep – 1st Oct 2004.

Molecular Sophe: An integrated approach to the analysis of CW and pulsed EPR spectra of biomolecules

Hanson, G. R., Noble, C. J., Mitchell, A., Benson, S., Lane, I., McEwan, A. G. and Gates, K. E. (2004). Molecular Sophe: An integrated approach to the analysis of CW and pulsed EPR spectra of biomolecules. 4th Asia Pacific EPR/ESR Symposium, Bangalore, India, 22-25 November, 2004.

Respiratory gene clusters of Metallosphaera sedula

Kappler, U., Sly, L. I. and McEwan, A. G. (2004). Respiratory gene clusters of Metallosphaera sedula. VAAM (German Microbiology Society) Meeting, Braunschweig, 28-31 March, 2004.

CW and pulsed EPR spectroscopy reveal a new structural motif for the active site Mo centre and an unusual [4Fe-4S](+) cluster in dimethylsulfide dehydrogenase.

Hanson, GR, Noble, CJ, McDevitt, CA and McEwan, AG (2003). CW and pulsed EPR spectroscopy reveal a new structural motif for the active site Mo centre and an unusual [4Fe-4S](+) cluster in dimethylsulfide dehydrogenase.. 11th International Conference on Biological Inorganic Chemistry, Caims Australia, Jul 19-23, 2003. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/S0162-0134(03)80633-5

CW and Pulsed EPR Spectroscopy Reveal a New Structural Motif for the Active Site Mo Centre and an Unusual [4Fe-4S]+ Cluster in Dimethylsulfide Dehydrogenase

Hanson, G. R., Noble, C. J., McDevitt, C. and McEwan, A. G. (2003). CW and Pulsed EPR Spectroscopy Reveal a New Structural Motif for the Active Site Mo Centre and an Unusual [4Fe-4S]+ Cluster in Dimethylsulfide Dehydrogenase. 45th Rocky Mountain Conference on Analytical Chemistry, Denver, Colorado, 27-31 July 2003. Milestone Presentations.

CW and pulsed EPR spectroscopy revealnext term a new structural motif for the active site Mo centre and an unusual [4Fe-4S]+ cluster in dimethylsulfide dehydrogenase

Hanson, Graeme R., Noble, Christopher J., McDevitt, Christopher A. and McEwan, Alastair G. (2003). CW and pulsed EPR spectroscopy revealnext term a new structural motif for the active site Mo centre and an unusual [4Fe-4S]+ cluster in dimethylsulfide dehydrogenase. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19 - 23 July 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80633-5

Direct electrochemistry of bacterial molybdoenzymes

Aguey-Zinsou, K. F., Bernhardt, P. V. and McEwan, A. G. (2003). Direct electrochemistry of bacterial molybdoenzymes. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 Jul 2003. New York, NY, USA: Elsevier Science Inc. doi: 10.1016/S0162-0134(03)80545-7

Probing molecular properties: Direct electrochemistry of sulfite dehydrogenase from Starkeya novella

Aguey, F.K., Bernhardt, P. V., Kappler, U. and McEwan, A. G. (2003). Probing molecular properties: Direct electrochemistry of sulfite dehydrogenase from Starkeya novella. Biospektrum, Berlin, 23-26 March, 2003.

Site-directed mutagenesis of dimethylsulfoxide reductase from Rhodobacter capsulatus: The critical roles of tyrosine-114 and tryptophan-116

McEwan, Alastair G., Ridge, Justin P., Aguey-Zinsou, Kondo-Francois, Bernhardt, Paul V. and Hanson, Graeme R. (2003). Site-directed mutagenesis of dimethylsulfoxide reductase from Rhodobacter capsulatus: The critical roles of tyrosine-114 and tryptophan-116. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19 - 23 July, 2003. New York: Elsevier. doi: 10.1016/S0162-0134(03)80496-8

Structural characterisation of the Mo(V) High-g unsplit species from Rhodobacter capsulatus dimethylsulfoxide reductase

Hanson, G. R., Lane, I., Noble, C. J., McEwan, A. G. and Benson, N. (2003). Structural characterisation of the Mo(V) High-g unsplit species from Rhodobacter capsulatus dimethylsulfoxide reductase. 45th Rocky Mountain Conference on Analytical Chemistry, Denver, USA, 27-31 July, 2003.

Structural characterisation of the Mo(V) High-g unsplit species from Rhodobacter capsulatus dimethylsulfoxide reductase

Hanson, Graeme R., Lane, Ian, Noble, Christopher J., McEwan , Alastair G. and Benson, Neil (2003). Structural characterisation of the Mo(V) High-g unsplit species from Rhodobacter capsulatus dimethylsulfoxide reductase. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 July, 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80633-5

The Rhodobacter capsulatus dor promoter: A useful tool for the heterologous expression of redox proteins

Kappler, U. and McEwan, A. G. (2003). The Rhodobacter capsulatus dor promoter: A useful tool for the heterologous expression of redox proteins. Biospektrum, Berlin, 23-26 March, 2003.

A comparative study of oxidative stress defence mechanisms in Neisseria meningitidis and Neisseria gonorrhoeae

Seib, K. L., Tseng, Hsing-Ju, McEwan, A. G. and Jennings, M. P. (2002). A comparative study of oxidative stress defence mechanisms in Neisseria meningitidis and Neisseria gonorrhoeae. 13th International Pathogenic Neisseria Conference 2002, Oslo, Norway, 1st - 6th September, 2002. Norwegian Institute of Public Health.

OxyR acts as a repressor of catalase expression in Neisseria gonorrhoeae

Tseng, Hsing-Ju, McEwan, Alastair G., Apicella, Michael and Jennings, Michael P. (2002). OxyR acts as a repressor of catalase expression in Neisseria gonorrhoeae. 13th International Pathogenic Neisseria Conference 2002, Oslo, 1st - 6th September, 2002.

Virulence factor expression in Neisseria gonorrhoeae: Regulation by manganese and the Mn(II) binding protein MntC

Tseng, H. J., Srikhanta, Y., McEwan, A. G., Apicella, M. A. and Jennings, M. P. (2002). Virulence factor expression in Neisseria gonorrhoeae: Regulation by manganese and the Mn(II) binding protein MntC. 13th International Pathogenic Neisseria Conference 2002, Oslo, Norway, 1st - 6th September, 2002. Norway: Norwegian Institute of Public Health.

A role for manganese and the MntABC primary transporter in the superoxide dismutase-independent protection of Neisseria gonorrhoeae

McEwan, A. G., Tseng, H. J., Srikhanta, Y. N. and Jennings, M. P. (2001). A role for manganese and the MntABC primary transporter in the superoxide dismutase-independent protection of Neisseria gonorrhoeae. SEB Annual Meeting, Canterbury, UK, March, 2001.

An EPR spectroscopic characterisation of dimethylsulfide dehydrogenase from rhodovulum sulfidophilum

McDevitt, C. A., Hanson, G. R. and Mcewan, A. G. (2001). An EPR spectroscopic characterisation of dimethylsulfide dehydrogenase from rhodovulum sulfidophilum. 43rd Rocky Mountain Conference on Analytical Chemistry, Denver, Colorado, USA, 29 July to 2 August 2001. Denver: Milestone Presentations.

Dimethylsulfide dehydrogenase from rhodovulum sulfidophilum: EPR spectroscopy and biochemical analysis reveal its place in the DMSO reductase family of molybdenum enzymes

Hanson, G. R., McDevitt, C. A. and Mcewan, A. G. (2001). Dimethylsulfide dehydrogenase from rhodovulum sulfidophilum: EPR spectroscopy and biochemical analysis reveal its place in the DMSO reductase family of molybdenum enzymes. 10th International Conference on Bioinoragnic Chemistry, Florence, Italy, 26th - 31st August, 2001.

Xsophe and its application to the analysis of EPR spectra from the molybdoenzymes dimethylsulfoxide reductase and dimethylsulfide dehydrogenase

Noble, C. J., McDevitt, C. A., Lane, I., Griffin, M. P., Mcewan, A. G., Gates, K. E. and Hanson, G. R. (2001). Xsophe and its application to the analysis of EPR spectra from the molybdoenzymes dimethylsulfoxide reductase and dimethylsulfide dehydrogenase. 14th Conference of ISMRM, Rhodes, Greece, 19-23 August 2001. Italy: Dan Knassim Ltd.

Characterization of PpsR the central regulator of photosynthesis gene expression in Rhodobacter sphaeroides in response to oxygen

Dodd, H. N., Horne, I., Gomelsky, M., Kaplan, S., Pemberton, J. M. and McEwan, A. G. (2000). Characterization of PpsR the central regulator of photosynthesis gene expression in Rhodobacter sphaeroides in response to oxygen. International Symposium on Phototrophic Prokaryotes (10th, 2000, ISPP), Barcelona, 26-31 August 2000.

EPR studies of sulfur centered radicals in dimethylsulfoxide reductase

Lane, I., Hanson, G. R., McEwan, A. G., Noble, C. J. and Pilbrow, J. (2000). EPR studies of sulfur centered radicals in dimethylsulfoxide reductase. ANZMAG 2000, Mt Buller, Vic, 13-17 February 2000. Australia: ANZMAG.

Spectroscopic characterisation of two complimentary molybdoenzymes

Hanson, G. R., McDevitt, C. A., Ridge, J. P. and McEwan, A. G. (2000). Spectroscopic characterisation of two complimentary molybdoenzymes. Brisbane Inorganic Chemistry Symposium (BICS III), Dept of Chemistry, UQ, 30 November 2000. Upper Mt Gravatt, Qld.: Queensland Branch (Inorganic Chemistry Group) of the Royal Australian Chemical Institute.

The DMSO reductase family of molybdenum enzymes in purple phototrophic bacteria

McEwan, A. G., Ridge, J. P., Mc Devitt, C., Pfluger, C. M., Hanson, G. R., Bell, A. and Tonge, P. (2000). The DMSO reductase family of molybdenum enzymes in purple phototrophic bacteria. International Symposium on Phototrophic Prokaryotes (10th, 2000, ISPP), Barcelona, Spain, 26-31 August 2000.

The role of the response regulator DorR in phototrophic and anaerobic dark growth of Rhodobacter capsulatus

Kappler, U., Houston, W. and McEwan, A. G. (2000). The role of the response regulator DorR in phototrophic and anaerobic dark growth of Rhodobacter capsulatus. International Symposium on Phototrophic Prokaryotes (10th, 2000, ISPP), Barcelona, Spain, 26-31 August 2000.

Characterisation of Dimethylsulfoxide reductase and DorC from Rhodobacter capsulatus: implications for electron transfer

Lane, I., Shaw, A., Ridge, J. P., Hanson, G. R. and Mcewan, A. G. (1999). Characterisation of Dimethylsulfoxide reductase and DorC from Rhodobacter capsulatus: implications for electron transfer. The Fourth Brisbane Biological Chemistry Symposium, Brisbane, 9 July 1999. Brisbane: Univ. of Qld.

Molybdenum-Containing Enzymes: Dimethyl Sulfoxide Reductase as a model

Ridge, J. P., Hanson, G. R. and Mcewan, A. G. (1999). Molybdenum-Containing Enzymes: Dimethyl Sulfoxide Reductase as a model. RACI 1999 Brisbane Inorganic Chemistry Symposium, Brisbane, 6 December 1999. Australia: Royal Australian Chemical Institute (Qld. Branch).

Spectroscopic and crystallographic characterisation of dimethylsulfoxide reductase from Rhodobacter capsulatus: structure and implications for electron transfer

Lane, I., Hanson, G. R., Mcewan, A. G., McAlpine, A. S. and Bailey, S. (1999). Spectroscopic and crystallographic characterisation of dimethylsulfoxide reductase from Rhodobacter capsulatus: structure and implications for electron transfer. Joint meeting of the Inorganic Division of the RACI, Wellington, NZ, 31 Jan - 4 Feb 1999. Wellington, NZ: NZ Institute of Chemistry.

Dimethylsulphoxide Reductase From Purple Phototrophic Bacteria: Structures and Mechanism(s)

McEwan, A.G., Hanson, G.R. and Bailey, S. (1998). Dimethylsulphoxide Reductase From Purple Phototrophic Bacteria: Structures and Mechanism(s). 665th Meeting University of Southampton: Royal Irish Academy Lecture, Southampton, United Kingdom, 1998. Colchester, England: Portland Press. doi: 10.1042/bst0260390

EPR Spectroscopy of Dimethylsulfoxide Reductase from Rhodobacter capsulatus

Hanson, G.R., Lane, I. and McEwan, A.G. (1998). EPR Spectroscopy of Dimethylsulfoxide Reductase from Rhodobacter capsulatus. A joint 29th AMPERE — 13th ISMAR International Conference on Magnetic Resonance and Related Phenomena Revisited, Berlin, Germany, 2-7 August, 1998. Berlin, Germany: Springer Wien. doi: 10.1007/BF03162015

EPR and X-ray Crystallographic Studies of Dimethylsulfoxide Reductase from Rhodobacter capsulatus: Implications for Electron Transfer and Catalysis

Lane, I., Solomon, P.S., Shaw, A.L., McAlpine, A.S., Hanson, G.R., Bailey, S. and McEwan, A.G. (1997). EPR and X-ray Crystallographic Studies of Dimethylsulfoxide Reductase from Rhodobacter capsulatus: Implications for Electron Transfer and Catalysis. 39th Rocky Mountain Conference, Denver, Colorado, U.S.A., 3-7 August, 1997.

EPR and X-ray crystallographic studies of dimethylsulfoxide reductase from Rhodobacter capsulatus: Implications for electron transfer and catalysis

Lane, Ian, Solomon, Peter S., Shaw, Anthony L., McAlpine, Alan S., Hanson, Graeme R., Bailey, Susan and McEwan, Alastair G. (1997). EPR and X-ray crystallographic studies of dimethylsulfoxide reductase from Rhodobacter capsulatus: Implications for electron transfer and catalysis. ICBIC 8: 8th International Conference on Bioinorganic Chemistry, Yokohama, Japan, 27 July-1 August 1997. New York, NY, U.S.A.: Elsevier. doi: 10.1016/S0162-0134(97)89892-3

Molecular properties of DMSO reductase: A model molybdenum oxotransferase

Shaw, A. L., Solomon, P. S., McAlpine A. S., Bailey S., Hanson, G. R. and McEwan, A. G. (1996). Molecular properties of DMSO reductase: A model molybdenum oxotransferase. 21st Annual Lorne Conference on Protein Structure and Function, Lorne, VIC, Australia, 4-8 February 1996.

Molecular studies of dimethylsulfoxide (DMSO) reductase from Rhodobacter capsulatus

Shaw, A. L., Hanson, G. R., Lane, I., Solomon, P. S., Cobine, P., McEwan, A. G. and Benson, N. (1995). Molecular studies of dimethylsulfoxide (DMSO) reductase from Rhodobacter capsulatus. ICBIC-7: Seventh International Conference on Bioinorganic Chemistry, Lübeck, Germany, 3-8 September 1995. New York, NY, U.S.A.: Elsevier.

E.p.r. characterisation of the molybdenum centre of Rhodobacter capsulatus dimethylsulphoxide reductase: New signals on reduction with Na2S2O4

Bennett, B., Benson, N., McEwan, A. G. and Bray, R. C. (1994). E.p.r. characterisation of the molybdenum centre of Rhodobacter capsulatus dimethylsulphoxide reductase: New signals on reduction with Na2S2O4.

Bacterial dimethyl sulphoxide reductases and nitrate reductases

McEwan, A. G., Benson, N., Bonnett, T. C., Hanlon, S. P., Ferguson, S. J., Richardson, D. J. and Jackson, J. B. (1991). Bacterial dimethyl sulphoxide reductases and nitrate reductases. doi: 10.1042/bst0190605