Dr Barbara Lingwood

Research Fellow

UQ Centre for Clinical Research
Faculty of Medicine
b.lingwood@uq.edu.au
+61 7 334 66016

Overview

Barbara’s research has focussed on improving outcomes for babies who have suffered from a lack of oxygen during birth.

Barbara completed her BSc(Hons), MSc and PhD at the University of Melbourne. She commenced working at the Perinatal Research Centre in 1998 and her research here has included:

Early prediction of outcome in babies who have suffered a lack of oxygen during birth. Severe perinatal asphyxia occurs in about 1 in every 500 births. The reduced supply of oxygen to the brain during birth can result in death or neurological disability for life. It is clear however that brain cells do not die immediately but die as a result of a cascade of events occurring over the period hours to days after hypoxia. This cascade provides a window of opportunity when it may be possible to interrupt the events leading to brain cell death and thus reduce the severity of brain injury. However the opportunity to improve outcome may only last 12 – 24 hours following the insult. It is therefore necessary to identify quickly infants at risk of a poor neurodevelopmental outcome so that potential benefits of neural rescue therapies can be maximised.The factors that are responsible for differences between babies in their ability to compensate for reduced oxygen supply. If these factors can be identified it may be possible to identify infants who are at risk of neural injury due to low tolerance, and who will benefit from targeted intervention to prevent injury. It may also be possible to reduce or prevent neural injury by mimicking those mechanisms which allow some babies to compensate more effectively for lack of oxygen.The use of bio-impedance for continuous monitoring of fluid status in babies born <1500g.Body composition in babies born to mothers with diabetes and/or obesity.

Qualifications

  • PhD, University of Melbourne
  • Master of Science, University of Melbourne
  • Bachelor of Science (Honours), University of Melbourne

Publications

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Supervision

View all Supervision

Publications

Book Chapter

Journal Article

Conference Publication

  • Eiby, Yvonne, Bjorkman, Tracey, Wixey, Julie, Chand, Kirat, Colditz, Paul and Lingwood, Barbara (2016). Pilot trial of early blood transfusions for supporting cardiovascular function and cerebral oxygen delivery in preterm piglets. In: 30th Annual meeting Fetal and Neonatal Workshop of Australia and New Zealand, Magnetic Island, QLD, Australia, (). 19-21 May 2016.

  • Dong, S., Boashash, B., Azemi, G., Lingwood, B.E. and Colditz, P.B. (2013). Detection of perinatal hypoxia using time-frequency analysis of heart rate variability signals. In: 2013 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2013 - Proceedings. 2013 38th IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2013, Vancouver, Canada, (939-943). 26-31 May 2013. doi:10.1109/ICASSP.2013.6637787

  • Dong, Shiying, Azemi, Ghasem, Lingwood, Barbara, Colditz, Paul B. and Boashash, Boualem (2012). Performance evaluation of multi-component instantaneous frequency estimation techniques for heart rate variability analysis. In: ISSPA 2012 : 2012 11th International Conference on Information Science, Signal Processing and thei Applications. 11th International Conference on Information Science, Signal Processing and their Applications, ISSPA 2012, Montreal, QC Canada, (1211-1216). 2 - 5 July 2012. doi:10.1109/ISSPA.2012.6310477

  • Dong, Shiying, Mesbah, Mostefa, Lingwood, Barbara E., O’ Toole, John M. and Boashash, Boualem (2011). Time-frequency analysis of heart rate variability in neonatal piglets exposed to hypoxia. In: Alan Murray, Annual Proceedings of Computing in Cardiology. 38th Annual Scientific Conference of Computing in Cardiology, Hangzhou, China, (701-704). 18-21 September 2011.

  • Dong, Shiying, Xu, Fangfei, Lingwood, Barbara, Mesbah, Mostefa and Boashash, Boualem (2010). R-wave detection: A comparative analysis of four methods using newborn piglet ECG. In: Information Sciences Signal Processing and their Applications (ISSPA), 2010 10th International Conference on. 10th International Conference on Information Sciences Signal Processing and their Applications, Kuala Lumpur, Malaysia, (320-323). 10-13 May 2010. doi:10.1109/ISSPA.2010.5605472

  • Lingwood, B. E., Dodrill, P., Davies, P. S. W., Callaway, L. and Colditz, P. B. (2008). Measurement of infant body composition using the pea pod and bio-impedance analysis. In: Perinatal Society of Australia and New Zealand 12th Annual Congress, Gold Coast, Australia. Perinatal Society of Australia and New Zealand 12th Annual Congress, Gold Coast, Australia, (A99-A99). 20–23 April 2008. doi:10.1111/j.1440-1754.2008.01299.x

  • Cornish, B.H., Lingwood, B.E. and Ward, L.C (2007). Can bioimpedance spectroscopy (BIS) tell us about the form of lymphoedema?. In: Scharfetter, H. and Merwa, R., IFMBE Proceedings - 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography. 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography, Graz, Austria, (795-798). 29th August - 2nd September, 2007.

  • Lingwood, B. E, Healy, G. N., Kecskes, Z., Dunster, K. R., Gray, P. H., Ward, L. C. and Colditz, P. B. (2007). Cerebral impedance following hypoxia/ischaemia in the human infant. In: Hermann Scharfetter and Robert Merwa, IFBME Proceedings - 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography. 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography, Graz, Austria, (600-603). 29 August - 2 September, 2007. doi:10.1007/978-3-540-73841-1

  • Harris, T. A., Lingwood, B. E., Healy, G. N. and Colditz, P. B. (2005). Hormonal responses to acute hypoxia in the neonate. In: Royal Brisbane and Women's Hospital Health Care Symposium, Brisbane, Australia, (). October, 2005.

  • Bjorkman, S. Tracey, Foster, Kelley A., O’Driscoll, Stephanie M., Healy, Genevieve N., Lingwood, Barbara E. and Colditz, Paul B. (2005). Hypoxic/Ischemic models in newborn piglet: A constant versus variable approach. In: FNPS 2005: 32nd Annual Meeting of the Fetal and Neonatal Physiological Society, Glenelg, SA, Australia, (). 25-28 September 2005.

  • Lingwood, B. E., Healy, G. N. and Colditz, P. B. (2004). Acute global hypoxia - do all babies respond in the same way?. In: Integrating Science & Perinatal Practice: Controversies & Dilemmas. Perinatal Society of Australia & New Zealand, Sydney, (A39-A39). 15-18 Mar, 2004.

  • Lingwood, B. E., Healy, G. N. and Colditz, P. B. (2004). Acute global hypoxia - do all babies respond in the same way?. In: Royal Brisbane and Women's Hospital Health Care Symposium. Royal Brisbane and Women's Hospital Health Care Symposium, Brisbane, (1-1). 19-22 October, 2004.

  • Colditz, P., Finkelstein, D., Lingwood, B., Pow, D., Rauen, T., Scott, H., Sullivan, R. K. P. and Williams, S. M. (2004). Glutamate transporter expression patterns vary in mammals with differing levels of cortical complexity. In: Society for Neuroscience Annual Meeting 2004, San Diego, California, (). 23-27 October 2004.

  • Buckley, S. T., O'Driscoll, S. M., Healy, G. N., Lingwood, B. E. and Colditz, P. B. (2004). Hypoxic/ischemic models in newborn piglet: a constant versus variable approach. In: Royal Brisbane and Women's Hospital Health Care Symposium. Royal Brisbane and Women's Hospital Health Care Symposium, Brisbane, (). 19-22 October, 2004.

  • Naidoo, T. L., Lingwood, B. E., Health, G. N., O'Driscoll, S., Colditz, P. B. and Pow, D. V. (2004). Loss of glial glutamate transporters and induction of neuronal expression of GLT-1B in the hypoxic neonatal pig brain. In: Proceedings of the Australian Neuroscience Society 24th Annual Meeting. Australian Neuroscience Society 24th Annual Meeting (ANS 2004), Melbourne, VIC, Australia, (). 27-30 January, 2004.

  • Lingwood, B. E., Healy, G. N., Williams, S., Pow, D. V. and Colditz, P. B. (2004). MAP2 as an early predictor of neural injury following neonatal hypoxia in piglets. In: Integrating Science and Perinatal Practice: Controversies and Dilemmas. Perinatal Society of Australia and New Zealand 8th Annual Congress 2004, Sydney, Australia, (10-10). 15-18 March 2004.

  • Lingwood, B. E., Healy, G. N., Williams, S., Pow, D. V. and Colditz, P. B. (2004). MAP2 as an early predictor of neural injury following neonatal hypoxia in piglets. In: Royal Brisbane & Women's Hospital Health Care Symposium. Royal Brisbane and Women's Hospital Health Care Symposium, Brisbane, Australia, (1-1). 19-22 October, 2004.

  • Lingwood, B. E., Healy, G. N., Williams, S. M., Pow, D. V. and Colditz, P. B. (2004). MAP2 as an early predictor of neural injury following neonatal hypoxia in piglets. In: Royal Brisbane and Women’s Hospital Health Care Symposium, Brisbane, (). 19-22 October 2004.

  • Healy, G. N. and Lingwood, B. E. (2004). Reference values for head and whole body multi-frequency bio-impedance data in neonates less than 12hrs postpartum. In: Royal Brisbane & Women's Hospital Health Care Symposium. Royal Brisbane & Women's Hospital Health Care Symp, Brisbane, (1-1). 19-22 Oct, 2004.

  • Lingwood, B. E., Dunster, K. R. and Ward, L. C. (2004). Reliability of single frequency impedance in an electrically noisy environment. In: Proceedings of the XII International Conference on Electrical Bio-Impedance. XII International Conference on Electrical Bio-Impedance, Gdansk, Poland, (297-300). 20-24 Jun, 2004.

  • Lingwood, B. E., Dunster, K. R., Healy, G. N., Ward, L. C. and Colditz, P. B. (2003). Cerebral impedance and neurological outcome following a mild or severe hypoxic/ischemic episode in neonatal piglets. In: Annual Queensland Health and Medical Scientific Meeting. Annual Queensland Health and Medical Scientific Meeting, Brisbane, QLD, (). 25 - 26 November 2003.

  • Lingwood, B. E., Dunster, K. R., Healy, G. N., Ward, L. C. and Colditz, P. B. (2003). Cerebral impedance and neurological outcome following a mild or severe hypoxic/ischemic episode in neonatal piglets. In: Herston Campus Health Care Symposium. Herston Campus Health Care Symposium, Brisbane, QLD, (). 24-28 March 2003.

  • Lingwood, B. E., Dunster, K. R., Healy, G. N. and Colditz, P. B. (2003). Effect of cooling on cerebral and whole body electrical impedance. In: Herston Campus Health Care Symposium. Herston Campus Health Care Symposium, Brisbane, Australia, (27-27). 24-28 March , 2003.

  • Foster, K. A., Colditz, P. B., Lingwood, B. E., Burke, C. and Dunster, K. R. (2003). Prediction of outcome from physiological variables during hypoxic/ischaemic insult. In: Proceedings of the Herston Campus Health Care Symposium. Herston Campus Health Care Symposium, Brisbane, (15-15). 24-28 March, 2003.

  • Lingwood, B. E., Dunster, K. R., Healy, G. N. and Colditz, P. B. (2002). Effect of cooling on cerebral and whole body electrical impedence. In: Proceedings of the Australian Health and Medical Research Congress. The Australian Health and Medical Research Congress, Melbourne, Australia, (). November 2002.

  • Foster, K. A., Colditz, P. B., Lingwood, B. E., Burke, C. and Dunster, K. R. (2002). Prediction of outcome from physiological variables during hypoxic/schemic insult. In: Proceedings of the 32nd Annual Meeting of the Society for Neuroscience. 32nd Annual Meeting of the Society for Neuroscience, Orlando, (488.6-488.6). 2-7 November, 2002.

  • Lingwood, B. E., Dunster, K. R., Colditz, P. B. and Ward, L. C. (2001). Non-invasive detection of cerebral edema in the neonatal piglet. In: Proceedings of the XI International Conference on Electrical Bio-Impedance. Oslo. XI International Conference on Electrical Bio-Impedance, Oslo, Norway, (655-658). 17-21 June 2001.

  • Lingwood, B. E., Dunster, K. R., Colditz, P. B. and Ward, L.C. (2001). Non-invasive detection of cerebral edema in the neonatal piglet. In: Sverre Grimes, Orjan G Martinsen and Heidi Bruvoll, Proceedings of the XI International Conference on Electrical Bio-Impedance. Oslo, Norway. XI International Conference on Electrical Bio-Impedence, Oslo, Norway, (655-658). 17-21 June 2001.

  • Charles, B. G., Coghlan, J. P., Colditz, P. B., Lingwood, B. E. and Ward, L. C. (2000). Is there advantage in using multiple frequency bioelectrical impedance analysis (MFBIA) for the prediction of gentamicin distribution volume in neonates?. In: Fifth International Symposium on In Vivo Body Composition Studies Program & Abstracts. 5th International Symposium on In Vivo Body Composition Studies, New York, United States, (196-198). 7-9 October, 1999. doi:10.1111/j.1749-6632.2000.tb06444.x

  • Lingwood, B. E., Dunster, K. R., Colditz, P. B. and Ward, L. C. (2000). Non-invasive detection of the early stages of post-hypoxic neuronal injury. In: Proceedings of the Perinatal Society of Australia and New Zealand. , Brisbane, (). 12-15 March, 2000.

  • Lingwood, B. E., Ward, L. C., Dunster, K. R. and Colditz, P. B. (2000). The non-invasive measurement of cerebral bioimpedance for detection of cerebral oedema in the neonatal piglet. In: 14th National Workshop on Fetal and Neonatal Physiology. 14th National Workshop on Fetal and Neonatal Physiology, Brisbane, Australia, (). 16-18 March, 2000.

  • Lingwood, B. E., Colditz, P. B. and Ward, L. C. (1999). Biomedical applications of electrical impedance analysis. In: ISSPA'99 Proceedings of the Fifth International Symposium on Signal Processing and its Application. ISSPA '99, Brisbane Convention Cen., (367-368). 22-25 August, 1999.

  • Colditz, P. B., Buck, L. J., Foster, K. and Lingwood, B. E. (1999). Can signal processing help prevent brain damage in the newborn?. In: Proceedings of the fifth International Symposium on Signal Processing and its Application. Fifth International Symposium on Signal Processing, Brisbane Convention & Exhibition Cen., Qld., (345-349). 22-25 Aug, 1999. doi:10.1109/ISSPA.1999.818183

  • Buck, L. J., Lingwood, B. E. and Colditz, P. B. (1999). Cerebral function monitoring in the neonate. In: Proceedings of the 3rd Annual Congress of the Perinatal Society of Australia and New Zealand and The 6th Annual conference of ANNA. The Perinatal Society of Australia and New Zealand, Hotel Sofitel Melbourne, (165). 21 -24 March 1999.

  • Lingwood, B. E. (1999). Detection of cerebral impedance using electrical impedance analysis. In: The First Workshop on EEG Analysis and Modeling. The First Workshop on EEG Analysis and Modeling, Hilton Hotel Brisbane, (). 1 December 1999.

  • Charles, B. G., Coghlan, J. P., Colditz, P. B., Lingwood, B. E. and Ward, L. C. (1999). Measurement of extracellular fluid volume in the neonate using multiple frequency bioelectrical impedance analysis. In: Proceedings of the Royal Australasian College of Physicians. Royal Australasian College of Physicians Annual Scientific Conference, Perth, Western Australia, (). Ocober, 1999.

  • Lingwood, B. E., Coghlan, J. P., Ward, L. C., Charles, B. G. and Colditz, P. B. (1999). Prediction of aminoglycoside distribution space in neonates by multiple frequency bioelectrical impedance analysis. In: Proceedings of the Perinatal Society of Australia and New Zealand. 3rd Annual Perinatal Society of Australia & New Zealand Congs, Sofitel Hotel, Melbourne, (P91). 21-24 March, 1999.

  • Lingwood, B.E., Bell, R.J., Hennessy, D.P. and Wintour, E.M. (1983). Potential sites for hormonal-regulation of amniotic-fluid in the sheep n the last 3rd of gestation. In: Abstracts of the International Satellite Symposium Perinatal Physiology and Behaviour In association with the XXIXth Congress of the International Union of physiological Sciences. International Satellite Symposium Perinatal Physiology and Behaviour In association with the XXIXth Congress of the International Union of physiological Sciences, Melbourne, VIC, Australia, (269-270). 22 - 26 August 1983. doi:10.1111/j.1440-1754.1983.tb02117.x

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision