Associate Professor Vicki Whitehall

Honorary Associate Professor

School of Clinical Medicine
Faculty of Medicine

Overview

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Bachelor of Science (Hons I), The University of Queensland
  • Bachelor of Science, The University of Queensland

Publications

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Journal Article

  • Bettington, Mark, Liu, Cheng, Gill, Anthony, Walker, Neal, Leggett, Barbara, Whitehall, Vicki and Rosty, Christophe (2019) BRAF V600E immunohistochemistry demonstrates that some sessile serrated lesions with adenomatous dysplasia may represent collision lesions. Histopathology, 75 1: 81-87. doi:10.1111/his.13851

  • Liu, Cheng, Fennell, Lochlan J., Bettington, Mark L., Walker, Neal I., Dwine, Joel, Leggett, Barbara A. and Whitehall, Vicki L. J. (2019) DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas. Clinical Epigenetics, 11 1: 90. doi:10.1186/s13148-019-0691-4

  • Mittal, Deepak, Lepletier, Ailin, Madore, Jason, Aguilera, Amelia Roman, Stannard, Kimberley, Blake, Stephen J., Whitehall, Vicki L. J., Liu, Cheng, Bettington, Mark L., Takeda, Kazuyoshi, Long, Georgina V., Scolyer, Richard A., Lan, Ruth, Siemers, Nathan, Korman, Alan, Teng, Michele W. L., Johnston, Robert J., Dougall, William C. and Smyth, Mark J. (2019) CD96 Is an Immune Checkpoint That Regulates CD8(+) T-cell Antitumor Function. Cancer Immunology Research, 7 4: 559-571. doi:10.1158/2326-6066.CIR-18-0637

  • Lannagan, Tamsin R. M., Lee, Young K., Wang, Tongtong, Roper, Jatin, Bettington, Mark L., Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q., Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Kobayashi, Hiroki, Putoczki, Tracey L., Hayakawa, Yoku, Leedham, Simon J., Abud, Helen E., Yilmaz, Omer H., Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A., Whitehall, Vicki L. J., Worthley, Daniel L. and Woods, Susan L. (2019) Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut, 68 4: 684-692. doi:10.1136/gutjnl-2017-315920

  • Fennell, Lochlan, Dumenil, Troy, Wockner, Leesa, Hartel, Gunter, Nones, Katia, Bond, Catherine, Borowsky, Jennifer, Liu, Cheng, McKeone, Diane, Bowdler, Lisa, Montgomery, Grant, Klein, Kerenaftali, Hoffmann, Isabell, Patch, Ann-Marie, Kazakoff, Stephen, Pearson, John, Waddell, Nicola, Wirapati, Pratyaksha, Lochhead, Paul, Imamura, Yu, Ogino, Shuji, Shao, Renfu, Tejpar, Sabine, Leggett, Barbara and Whitehall, Vicki (2019) Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals five distinct subtypes of colorectal adenocarcinomas. Cellular and Molecular Gastroenterology and Hepatology, 8 2: 269-290. doi:10.1016/j.jcmgh.2019.04.002

  • Liu, Cheng, Bettington, Mark L., Walker, Neal I., Dwine, Joel, Hartel, Gunter F., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018) CpG island methylation in sessile serrated adenomas increases with age, indicating lower risk of malignancy in young patients. Gastroenterology, . doi:10.1053/j.gastro.2018.07.012

  • Bettington, Mark, Rosty, Christophe, Whitehall, Vicki, Leggett, Barbara, McKeone, Diane, Pearson, Sally-Ann and Walker, Neal (2018) A morphological and molecular study of proposed early forms of the traditional serrated adenoma. Histopathology, . doi:10.1111/his.13714

  • Lannagan, Tamsin R. M., Lee, Young K., Wang, Tongtong, Roper, Jatin, Bettington, Mark L., Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Kobayashi, Hiroki, Putoczki, Tracey L., Hayakawa, Yoku, Leedham, Simon J., Abud, Helen E., Yilmaz, Ömer H., Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A., Whitehall, Vicki L. J., Worthley, Daniel L. and Woods, Susan L. (2018) Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut, 68 4: gutjnl-2017. doi:10.1136/gutjnl-2017-315920

  • Bettington, Mark, Brown, Ian, Rosty, Christophe, Walker, Neal, Liu, Cheng, Croese, John, Rahman, Tony, Pearson, Sally-Ann, McKeone, Diane, Leggett, Barbara and Whitehall, Vicki (2018) Sessile serrated adenomas in young patients may have limited risk of malignant progression. Journal of Clinical Gastroenterology, 1. doi:10.1097/MCG.0000000000001014

  • Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018) Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia. Epigenetics, 13 1: 40-48. doi:10.1080/15592294.2017.1411446

  • Fennell, Lochlan J., Jamieson, Saara, McKeone, Diane, Corish, Tracie, Rohdmann, Megan, Furner, Tori, Bettington, Mark, Liu, Cheng, Kawamata, Futoshi, Bond, Catherine, Van De Pols, Jolieke, Leggett, Barbara and Whitehall, Vicki (2018) MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation. BMC Cancer, 18 1: 1-7. doi:10.1186/s12885-017-3946-5

  • Kawamata, Futoshi, Patch, Ann-Marie, Nones, Katia, Bond, Catherine, McKeone, Diane, Pearson, Sally-Ann, Homma, Shigenori, Liu, Cheng, Fennell, Lochlan, Dumenil, Troy, Hartel, Gunter, Kobayasi, Nozomi, Yokoo, Hideki, Fukai, Moto, Nishihara, Hiroshi, Kamiyama, Toshiya, Burge, Matthew E., Karapetis, Christos S., Taketomi, Akinobu, Leggett, Barbara, Waddell, Nicola and Whitehall, Vicki (2018) Copy number profiles of paired primary and metastatic colorectal cancers. Oncotarget, 9 3: 3394-3405. doi:10.18632/oncotarget.23277

  • Bond, Catherine E. and Whitehall, Vicki L. J. (2018) How the BRAF V600E mutation defines a distinct subgroup of colorectal cancer: molecular and clinical implications. Gastroenterology Research and Practice, 2018 1-14. doi:10.1155/2018/9250757

  • Borowsky, Jennifer, Dumenil, Troy, Bettington, Mark, Pearson, Sally-Ann, Bond, Catherine, Fennell, Lochlan, Liu, Cheng, McKeone, Diane, Rosty, Christophe, Brown, Ian, Walker, Neal, Leggett, Barbara and Whitehall, Vicki (2017) The role of APC in WNT pathway activation in serrated neoplasia. Modern Pathology, 31 3: 495-504. doi:10.1038/modpathol.2017.150

  • Liu, Cheng, Walker, Neal I., Leggett, Barbara A., Whitehall, Vicki L. J., Bettington, Mark L. and Rosty, Christophe (2017) Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry. Modern Pathology, 30 12: 1728-1738. doi:10.1038/modpathol.2017.92

  • Fennell, Lochlan J. , Clendenning, Mark, McKeone, Diane M. , Jamieson, Saara H., Balachandran, Samanthy, Borowsky, Jennifer, Liu, John, Kawamata, Futoshi, Bond, Catherine E., Rosty, Christophe, Burge, Matthew E., Buchanan, Daniel D., Leggett, Barbara A.  and Whitehall, Vicki L. J. (2017) RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers. Familial Cancer, 17 1: 1-7. doi:10.1007/s10689-017-0003-0

  • Liu, Cheng, Mckeone, Diane M., Walker, Neal I., Bettington, Mark L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2017) GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features. Histopathology, 70 7: 1079-1088. doi:10.1111/his.13180

  • Scarpa, Aldo, Chang, David K., Nones, Katia, Corbo, Vincenzo, Patch, Ann-Marie, Bailey, Peter, Lawlor, Rita T., Johns, Amber L., Miller, David K., Mafficini, Andrea, Rusev, Borislav, Scardoni, Maria, Antonello, Davide, Barbi, Stefano, Sikora, Katarzyna O., Cingarlini, Sara, Vicentini, Caterina, McKay, Skye, Quinn, Michael C.J., Bruxner, Timothy J.C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, McLean, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wilson, Peter J., Anderson, Matthew J., Fink, J. Lynn, Newell, Felicity, Waddell, Nick, Holmes, Oliver, Kazakoff, Stephen H., Leonard, Conrad, Wood, Scott, Xu, Qinying, Nagaraj, Shivashankar Hiriyur, Amato, Eliana, Dalai, Irene, Bersani, Samantha, Cataldo, Ivana, Dei Tos, Angelo P., Capelli, Paola, Davì, Maria Vittoria, Landoni, Luca, Malpaga, Anna, Miotto, Marco, Whitehall, Vicki L.J., Leggett, Barbara A., Harris, Janelle L., Harris, Jonathan, Jones, Marc D., Humphris, Jeremy, Chantrill, Lorraine A., Chin, Venessa, Nagrial, Adnan M., Pajic, Marina, Scarlett, Christopher J., Pinho, Andreia, Rooman, Ilse, Toon, Christopher, Wu, Jianmin, Pinese, Mark, Cowley, Mark, Barbour, Andrew, Mawson, Amanda, Humphrey, Emily S., Colvin, Emily K., Chou, Angela, Lovell, Jessica A., Jamieson, Nigel B., Duthie, Fraser, Gingras, Marie-Claude, Fisher, William E., Dagg, Rebecca A., Lau, Loretta M.S., Lee, Michael, Pickett, Hilda A., Reddel, Roger R., Samra, Jaswinder S., Kench, James G., Merrett, Neil D., Epari, Krishna, Nguyen, Nam Q., Zeps, Nikolajs, Falconi, Massimo, Simbolo, Michele, Butturini, Giovanni, Van Buren, George, Partelli, Stefano, Fassan, Matteo, Khanna, Kum Kum, Gill, Anthony J., Wheeler, David A., Gibbs, Richard A., Musgrove, Elizabeth A., Bassi, Claudio, Tortora, Giampaolo, Pederzoli, Paolo, Pearson, John V., Waddell, Nicola, Biankin, Andrew V. and Grimmond, Sean M. (2017) Whole-genome landscape of pancreatic neuroendocrine tumours. Nature, 543 7643: 65-71. doi:10.1038/nature21063

  • Bettington, Mark, Walker, Neal, Rahman, Tony, Vandeleur, Ann, Whitehall, Vicki, Leggett, Barbara and Croese, John (2017) High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice. Internal Medicine Journal, 47 3: 318-323. doi:10.1111/imj.13329

  • Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, McKeone, Diane, Pearson, Sally-Ann, Leggett, Barbara and Whitehall, Vicki (2016) Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma. Gut, 66 1: 97-106. doi:10.1136/gutjnl-2015-310456

  • Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A. and Whitehall, Vicki L. J. (2016) RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget, 7 43: 70589-70600. doi:10.18632/oncotarget.12130

  • Bettington, Mark L., Walker, Neal I., Rosty, Christophe, Brown, Ian S., Clouston, Andrew D., McKeone, Diane M., Pearson, Sally Ann, Klein, Kerenaftali, Leggett, Barbara A. and Whitehall, Vicki L. (2015) A clinicopathological and molecular analysis of 200 traditional serrated adenomas. Modern Pathology, 28 3: 414-427. doi:10.1038/modpathol.2014.122

  • Bond, Catherine E., Bettington, Mark L., Pearson, Sally-Ann, McKeone, Diane M., Leggett, Barbara A. and Whitehall, Vicki (2015) Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups. BMC Cancer, 15 1: 20. doi:10.1186/s12885-015-1011-9

  • Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Mckeone, Diane, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara and Whitehall, Vicki (2015) Serrated tubulovillous adenoma of the large intestine. Histopathology, 68 4: 578-587. doi:10.1111/his.12788

  • Whitehall, V. L. J., Dumenil, T. D., McKeone, D. M., Bond, C. E., Bettington, M. L., Buttenshaw, R. L., Bowdler, L., Montgomery, G. W., Wockner, L. F. and Leggett, B. A. (2014) Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype. Epigenetics, 9 11: 1454-1460. doi:10.4161/15592294.2014.971624

  • Dumenil, Troy D., Wockner, Leesa F., Bettington, Mark, Mckeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014) Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue. Genes Chromosomes and Cancer, 53 7: 537-548. doi:10.1002/gcc.22164

  • Bond, Catherine E., Nancarrow, Derek J., Wockner, Leesa F., Wallace, Leanne, Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014) Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability. Plos One, 9 3: e91739. doi:10.1371/journal.pone.0091739

  • Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Wockner, Leesa, Whitehall, Vicki and Leggett, Barbara (2014) Critical appraisal of the diagnosis of the sessile serrated adenoma. American Journal of Surgical Pathology, 38 2: 158-166. doi:10.1097/PAS.0000000000000103

  • Day, Fiona L., Jorissen, Robert N., Lipton, Lara, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Christie, Michael, Li, Shan, Tsui, Cary, Tie, Jeannie, Desai, Jayesh, Xu, Zheng-Zhou, Molloy, Peter, Whitehall, Vicki, Leggett, Barbara A., Jones, Ian T., McLaughlin, Stephen, Ward, Robyn L., Hawkins, Nicholas J., Ruszkiewicz, Andrew R., Moore, James, Busam, Dana, Zhao, Qi, Strausberg, Robert L., Gibbs, Peter and Sieber, Oliver M. (2013) PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer. Clinical Cancer Research, 19 12: 3285-3296. doi:10.1158/1078-0432.CCR-12-3614

  • Rosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A. and Whitehall, Vicki L. J. (2013) Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management. Journal of Gastroenterology, 48 3: 287-302. doi:10.1007/s00535-012-0720-y

  • Bettington, Mark, Walker, Neal, Clouston, Andrew, Brown, Ian, Leggett, Barbara and Whitehall, Vicki (2013) The serrated pathway to colorectal carcinoma: current concepts and challenges. Histopathology, 62 3: 367-386. doi:10.1111/his.12055

  • Bond, Catherine E., Umapathy, Aarti, Buttenshaw, Ron L., Wockner, Leesa, Leggett, Barbara A. and Whitehall, Vicki L. J. (2012) Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers. Plos One, 7 10: e47483.1-e47483.9. doi:10.1371/journal.pone.0047483

  • Whitehall, Vicki L. J., Rickman, Celestine, Bond, Catherine E., Ramsnes, Ingunn, Greco, Sonia A., Umapathy, Aarti, McKeone, Diane, Faleiro, Rebecca J., Buttenshaw, Ron L., Worthley, Daniel L., Nayler, Sam, Zhao, Zhen Zhen, Montgomery, Grant W., Mallitt, Kylie-Ann, Jass, Jeremy R., Matsubara, Nagahide, Notohara, Kenji, Ishii, Tatsuhiro and Leggett, Barbara A. (2012) Oncogenic PIK3CA mutations in colorectal cancers and polyps. International Journal of Cancer, 131 4: 813-820. doi:10.1002/ijc.26440

  • Whitehall, Vicki and Leggett, Barbara (2011) Microsatellite instability: Detection and management in sporadic colorectal cancer. Journal of Gastroenterology and Hepatology, 26 12: 1697-1699. doi:10.1111/j.1440-1746.2011.06932.x

  • de Carcer, Daniel Aguirre, Ó Cuív, Páraic, Wang, Tingting, Kang, Seungha, Worthley, Daniel, Whitehall, Vicki, Gordon, Iain, McSweeney, Chris, Leggett, Barbara and Morrison, Mark (2011) Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon. ISME Journal, 5 5: 801-809. doi:10.1038/ismej.2010.177

  • Ó Cuív, Páraic, de Carcer, Daniel Aguirre, Jones, Michelle, Klaassens, Eline S., Worthley, Daniel L., Whitehall, Vicki L. J., Kang, Seungha, McSweeney, Christopher S., Leggett, Barbara A. and Morrison, Mark (2011) The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue. Microbial Ecology, 61 2: 353-362. doi:10.1007/s00248-010-9771-x

  • Ishii, Tatsushiro, Notohara, Kenji, Umapathy, Aarti, Mallitt, Kylie-Ann, Chikuba, Hiroshi, Moritani, Yukitoshi, Tanaka, Noriaki, Rosty, Christophe, Matsubara, Nagahide, Jass, Jeremy, Leggett, Barbara and Whitehall, Vicki (2011) Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomas. American Journal of Surgical Pathology, 35 2: 212-220. doi:10.1097/PAS.0b013e318205df20

  • Bond, Catherine E., Umapathy, Aarti, Ramsnes, Ingunn, Greco, Sonia A., Zhao, Zhen Zhen, Mallitt, Kylie-Ann, Buttenshaw, Ron L., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L.J. (2011) p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers. International Journal of Cancer, 130 7: 1567-1576. doi:10.1002/ijc.26175

  • Walker, R. Griff, Landmann, Juergen K., Hewett, David G., Worthley, Daniel L., Buttenshaw, Ron L., Knight, Ngaire, Webb, Penny M., Whiteman, David C., Whitehall, Vicki L. and Leggett, Barbara A. (2010) Hyperplastic Polyposis syndrome is associated with cigarette smoking, which may be a modifiable risk factor. The American Journal of Gastroenterology, 105 7: 1642-1647. doi:10.1038/ajg.2009.757

  • Worthley, Daniel L., Hewett, David G., Spring, Kevin J., Whitehall, Vicki L. J. and Leggett, Barbara A. (2010) Re: Protection from right-and left-sided colorectal neoplasms after colonoscopy: Population-based study. Journal of the National Cancer Institute, 102 13: 990-990. doi:10.1093/jnci/djq189

  • Leggett, Barbara and Whitehall, Vicki (2010) Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology, 138 6: 2088-2100. doi:10.1053/j.gastro.2009.12.066

  • Hinoue, Toshinori, Weisenberger, Daniel J., Pan, Fei, Campan, Mihaela, Kim, Myungjin, Young, Joanne, Whitehall, Vicki L., Leggett, Barbara A. and Laird, Peter W. (2009) Analysis of the Association between CIMP and BRAF(V600E) in Colorectal Cancer by DNA Methylation Profiling. PLoS One, 4 12: e8357. doi:10.1371/journal.pone.0008357

  • Loh, K, Chia, J. A., Greco, S., Cozzi, S.J., Buttenshaw, R.L., Bond, C.E., Simms, L.A., Pike, T., Young, J. P., Jass, J.R., Spring, K. J., Leggett, B. A. and Whitehall, V.L.J. (2008) Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development. Genes, Chromosomes & Cancer, 47 6: 449-460. doi:10.1002/gcc.20552

  • Worthley, D. L., Whitehall, V. L., Spring, K. J. and Leggett. B. A. (2007) Colorectal carcinogenesis: Road maps to cancer. World Journal of Gastroenterology, 13 28: 3784-3791.

  • Chia, June A., Simms, Lisa A., Cozzi, Sarah-Jane, Young, Joanne, Jass, Jeremy R., Walsh, Michael D., Spring, Kevin J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2006) SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers. BMC Cancer, 6 252: 1-6. doi:10.1186/1471-2407-6-252

  • Spring, Kevin, Zhao, Zhen Zhen, Karamatic, Rozemary, Walsh, Michael, Whitehall, Vicki, Pike, Tanya, Simms, Lisa, Young, Joanne, James, Michael, Montgomery, Grant, Appleyard, Mark, Hewett, David, Togashi, Kazutomo, Jass, Jeremy and Leggett, Barbara (2006) High prevalence of sessile serrated adenomas with BRAF mutations: A prospective study of patients undergoing colonoscopy. Gastroenterology, 131 5: 1400-1407. doi:10.1053/j.gastro.2006.08.038

  • Young, Joanne, Simms, Lisa A., Barker, Melissa A., Walsh, Michael D., Biden, Kelli G., Buttenshaw, Ron, Whitehall, Vicki L.J., Arnold, Sven, Jackson, Leigh, Kambara, Takeshi, Spring, Kevin J., Jenkins, Mark A., Walker, Graeme J., Hopper, John L., Leggett, Barbara A. and Jass, Jeremy R. (2005) Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer. Clinical Gastroenterology and Hepatology, 3 3: 254-263. doi:10.1016/S1542-3565(04)00673-1

  • Kambara, T., Simms, L. A., Whitehall, V. L. J., Spring, K. J., Wynter, C. V. A., Walsh, M. D., Barker, M. A., Arnold, S., McGivern, A., Matsubara, N., Tanaka, N., Higuchi, T., Young, J., Jass, J. R. and Leggett, B. A. (2004) BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut, 53 8: 1137-1144. doi:10.1136/gut.2003.037671

  • Kambara, Takeshi, Whitehall, Vicki L. J., Spring, Kevin J., Barker, Melissa A., Arnold, Sven, Wynter, Coral V. A., Matsubara, Nagahide, Tanaka, Noriaki, Young, Joanne P., Leggett, Barbara A. and Jass, Jeremy R. (2004) Role of inherited defects of MYH in the development of sporadic colorectal cancer. Genes, Chromosomes and Cancer, 40 1: 1-9. doi:10.1002/gcc.20011

  • Young, J. P., Simms, L. A., Biden, K. G., Wynter, C. V. A., Whitehall, V. L., Karamatic, R., George, J., Goldblatt, J., Walpole, I., Robin, S., Borten, M. M., Stitz, R. W., Searle, J., McKeone, D. M. and Fraser, L. A. (2001) Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings. American Journal of Pathology, 159 6: 2107-2116. doi:10.1016/S0002-9440(10)63062-3

  • Hourigan, L. F., Macdonald, G. A., Purdie, D., Whitehall, V. L. J., Shorthouse, C., Clouston, A. and Powell, E. E. (1999) Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology, 29 4: 1215-1219. doi:10.1002/hep.510290401

Conference Publication

Other Outputs

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

Completed Supervision