The University of Queensland

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity

Gandhi, Maher K., Hoang, Thanh, Law, Soi C., Brosda, Sandra, O'Rourke, Kacey, Tobin, Joshua W. D., Vari, Frank, Murigneux, Valentine, Fink, J. Lynn, Gunawardana, Jay, Gould, Clare M., Oey, Harald, Bednarska, Karolina, Delecluse, Susanne, Trappe, Ralf Ulrich, de Long, Lilia Merida, Sabdia, Muhammed Bilal, Bhagat, Govind, Hapgood, Greg, Blyth, Emily, Clancy, Leighton E., Wight, Joel, Hawkes, Eliza A., Rimsza, Lisa M., Maguire, Alanna, Bojarczuk, Kamil, Chapuy, Bjoern and Keane, Colm (2021). EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity. Blood, 137 (11), 1468-1477. doi: 10.1182/blood.2020008520

EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2

Cristino, Alexandre S., Nourse, Jamie, West, Rachael A., Sabdia, Muhammed Bilal, Law, Soi C., Gunawardana, Jay, Vari, Frank, Mujaj, Sally, Thillaiyampalam, Gayathri, Snell, Cameron, Gough, Madeline, Keane, Colm and Gandhi, Maher K. (2019). EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2. Blood, 134 (25), 2261-2270. doi: 10.1182/blood.2019000889

Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration

Tobin, Joshua W. D., Keane, Colm, Gunawardana, Jay, Mollee, Peter, Birch, Simone, Hoang, Thanh, Lee, Justina, Li, Li, Huang, Li, Murigneux, Valentine, Fink, J. Lynn, Matigian, Nicholas, Vari, Frank, Francis, Santiyagu, Kridel, Robert, Weigert, Oliver, Haebe, Sarah, Jurinovic, Vindi, Klapper, Wolfram, Steidl, Christian, Sehn, Laurie H., Law, Soi-Cheng, Wykes, Michelle N. and Gandhi, Maher K. (2019). Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration. Journal of Clinical Oncology, 37 (34), 3300-3309. doi: 10.1200/JCO.18.02365

Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S, Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone and Gandhi, Maher K (2018). Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL. Blood, 131 (16), 1809-1819. doi: 10.1182/blood-2017-07-796342

The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma

Keane, Colm, Gould, Clare, Jones, Kimberley, Hamm, David, Talaulikar, Dipti, Ellis, Jonathan, Vari, Frank, Birch, Simone, Han, Erica, Wood, Peter, Le-Cao, Kim-Anh, Green, Michael R., Crooks, Pauline, Jain, Sanjiv, Tobin, Josh, Steptoe, Raymond J. and Gandhi, Maher K. (2017). The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma. Clinical Cancer Research, 23 (7), 1820-1828. doi: 10.1158/1078-0432.CCR-16-1576

Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study

Keane, Colm, Vari, Frank, Hertzberg, Mark, Le Cao, Kim-Anh, Green, Michael R., Han, Erica, Seymour, John F., Hicks, Rodney J., Gill, Devinder, Crooks, Pauline, Gould, Clare, Jones, Kimberley, Griffiths, Lyn R., Talaulikar, Dipti, Jain, Sanjiv, Tobin, Josh and Gandhi, Maher K. (2015). Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study. Lancet Haematology, 2 (10), e445-e455. doi: 10.1016/S2352-3026(15)00150-7

Host genetic mutations and expression analyses in PTLD

Lees, Charlotte and Gandhi, Maher K. (2021). Host genetic mutations and expression analyses in PTLD. Post-transplant lymphoproliferative disorders. (pp. 39-50) edited by Vikas R. Dharnidharka, Michael Green, Steven A. Webber and Ralf Ulrich Trappe. Cham, Switzerland: Springer . doi: 10.1007/978-3-030-65403-0_4

Serum CD163 and TARC as circulating biomarkers in Hodgkin Lymphoma

Jones, Kimberley, Seymour, Louise and Gandhi, Maher K. (2015). Serum CD163 and TARC as circulating biomarkers in Hodgkin Lymphoma. Biomarkers in cancer. (pp. 955-978) edited by Victor R. Preedy and Vinood B. Patel. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-7681-4_5

Rituximab induced late-onset neutropenia

Keane, Colm, Nourse, Jamie P. and Gandhi, Maher K. (2012). Rituximab induced late-onset neutropenia. Rituximab: Pharmacology, Clinical Uses and Health Effects. (pp. 93-102) Hauppauge, NY United States: Nova Science Publishers.

Genetic susceptibility to complex traits: moving towards informed analysis of whole-genome screens

Green, Michael R., Camilleri, Emily, Gandhi, Maher K. and Griffiths, Lyn R. (2009). Genetic susceptibility to complex traits: moving towards informed analysis of whole-genome screens. Human genome: features, variations and genetic disorders. (pp. 167-180) edited by Akio Matsumoto and Mai Nakano. New York, NY, United States: Nova Science.

Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance

Wight, Joel, Blombery, Piers, Lickiss, Jennifer, Burgess, Melinda, Gould, Clare, Minson, Adrian, Swain, Fiona, Sabdia, Muhammed B., Gandhi, Maher K., Birchley, Andrew, Keane, Colm and Hawkes, Eliza A (2024). Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance. Haematologica. doi: 10.3324/haematol.2023.284600

EBNA2: a viral maestra conducting a symphony orchestra

Gandhi, Maher K. and Kelly, Gemma L. (2024). EBNA2: a viral maestra conducting a symphony orchestra. Blood, 143 (5), 384-385. doi: 10.1182/blood.2023022744

EBV-infected hematopoietic stem cells drive CAEBV

Khanna, Rajiv and Gandhi, Maher K. (2024). EBV-infected hematopoietic stem cells drive CAEBV. Blood, 143 (1), 2-4. doi: 10.1182/blood.2023022739

Epstein–Barr virus‐associated lymphomas decoded

Bednarska, Karolina, Chowdhury, Rakin, Tobin, Joshua W. D., Swain, Fiona, Keane, Colm, Boyle, Stephen, Khanna, Rajiv and Gandhi, Maher K. (2023). Epstein–Barr virus‐associated lymphomas decoded. British Journal of Haematology, 204 (2), 415-433. doi: 10.1111/bjh.19255

High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL

Sabdia, Muhammed B., Burgess, Melinda, Law, Soi Cheng, Thurgood, Lauren A, Kazakoff, Stephen, Swain, Fiona, Tobin, Joshua W.D., Mollee, Peter, Patch, Ann-Marie and Gandhi, Maher K (2023). High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL. Blood, 142 (Supplement 1), 3260-3260. doi: 10.1182/blood-2023-174149

Regulatory T cells hamper the efficacy of T-cell engaging bispecific antibody therapy

Casey, Mika, Lee, Carol, Kwok, Wing Yu, Law, Soi Cheng, Corvino, Dillon, Gandhi, Maher K., Harrison, Simon J. and Nakamura, Kyohei (2023). Regulatory T cells hamper the efficacy of T-cell engaging bispecific antibody therapy. Haematologica. doi: 10.3324/haematol.2023.283758

Genome-wide Transcription Factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

Subramanian, Shruthi, Thoms, Julie A I, Huang, Yizhou, Cornejo Paramo, Carina Paola, Koch, Forrest Charles, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Christopher Peter, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J, Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D, Pitson, Stuart M, Gandhi, Maher K., Lane, Steven W, Vafaee, Fatemeh, Wong, Emily, Gottgens, Berthold, Rokny, Hamid, Wong, Jason Wing Hon and Pimanda, John E (2023). Genome-wide Transcription Factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC. Blood Journal, 142 (17), 1448-1462. doi: 10.1182/blood.2023021120

P1127: FINAL ANALYSIS OF AUSTRALASIAN LEUKAEMIA & LYMPHOMA GROUP NHL29: A PHASE II STUDY OF IBRUTINIB, RITUXIMAB AND MINI-CHOP IN VERY ELDERLY PATIENTS WITH NEWLY DIAGNOSED DLBCL

Verner, Emma, Johnston, Amanda, Pati, Nalini, Hawkes, Eliza, Peng Lee, Hui, Cochrane, Tara, Yoon Cheah, Chan, Filshie, Robin, Purtill, Duncan, Sia, Hanlon, Enjeti, Anoop K, Brown, Christina, Murphy, Nicholas, Curnow, Jennifer, Lee, Kenneth, Gandhi, Maher, Butcher, Belinda and Trotman, Judith (2023). P1127: FINAL ANALYSIS OF AUSTRALASIAN LEUKAEMIA & LYMPHOMA GROUP NHL29: A PHASE II STUDY OF IBRUTINIB, RITUXIMAB AND MINI-CHOP IN VERY ELDERLY PATIENTS WITH NEWLY DIAGNOSED DLBCL. HemaSphere, 7 (Suppl), e129974b. doi: 10.1097/01.hs9.0000971404.12997.4b

Expanding the bacterial origins of nodular lymphocyte predominant Hodgkin lymphoma

Gandhi, Maher K. and Keane, Colm (2023). Expanding the bacterial origins of nodular lymphocyte predominant Hodgkin lymphoma. Haematologica, 108 (12), 3195-3196. doi: 10.3324/haematol.2023.283392

Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL

Verner, E., Johnston, A., Pati, N., Hawkes, E., Lee, H. P., Cochrane, T., Cheah, C. Y., Filshie, R., Purtill, D., Sia, H., Enjeti, A. K., Brown, C., Murphy, N., Curnow, J., Lee, K., Gandhi, M. K., Butcher, B. E. and Trotman, J. (2023). Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL. Hematological Oncology, 41 (S2), 426-427. doi: 10.1002/hon.3164_313

Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse

Swain, F., Burgess, M., Kempe, S., Sabdia, M., Wight, J., Hawkes, E., Mutsando, H., Talaulikar, D., Merida de Long, L., Hawula, Z., Birch, S., Wyche, P., Gandhi, M. K. and Keane, C. (2023). Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse. Hematological Oncology, 41 (S2), 278-279. doi: 10.1002/hon.3164_191

Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma

Tobin, J. W., Tsang, H., Patch, A., Keane, C., Law, S. C., Gunawardana, J., Blombery, P., Thompson, E. R., Sabdia, M. B., De Long, L. M., Nath, K., Kazakoff, S. H., Cheah, C., Amanuel, B., Cochrane, T., Butler, J., Johnston, A., Shanavas, M., Li, L., Shelton, V., Hershenfeld, S., Kridel, R., Seymour, J. F., MacManus, M. and Gandhi, M. K. (2023). Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma. Hematological Oncology, 41 (S2), 276-277. doi: 10.1002/hon.3164_189

Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial

Tobin, J. W., Jurinovic, V., Tsang, H., Roos, D., Tsang, R., Macann, A., Davis, S., Christie, D., Law, S., Nath, K., Sabdia, M., Patch, A. M., Gunawardana, J., Merida de Long, L., Hoster, E., Horn, H., Shanavas, M., Li, L., Cheah, C., Benhur, A., Hou, M., O'Brien, P., Johnston, A. M., Cochrane, T., Butler, J., Thompson, E., Blombery, P., Seymour, J. F., Gandhi, M. K. and MacManus, M. (2023). Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial. Hematological Oncology, 41 (S2), 216-217. doi: 10.1002/hon.3163_140

Resolution of melanoma to PD-1 blockade but simultaneous rapid progression of concomitant chronic lymphocytic leukemia

Burgess, Melinda, Keane, Colm, Tobin, Joshua W. D., Law, Soi Cheng, Griffin, Alison, Gill, Devinder, Ewing, Adam D., Atkinson, Victoria, Mollee, Peter, Sabdia, Muhammed B., Saunders, Nicholas and Gandhi, Maher K. (2023). Resolution of melanoma to PD-1 blockade but simultaneous rapid progression of concomitant chronic lymphocytic leukemia. Acta Haematologica, 146 (2), 166-171. doi: 10.1159/000527631

A coordinated strategy for a simple, pragmatic approach to the early identification of the ultra‐high‐risk patient with diffuse large B‐cell lymphoma

George, Hannah, Gunawardana, Jay, Keane, Colm, Hicks, Rod J. and Gandhi, Maher K. (2023). A coordinated strategy for a simple, pragmatic approach to the early identification of the ultra‐high‐risk patient with diffuse large B‐cell lymphoma. Internal Medicine Journal, 53 (7), 1105-1109. doi: 10.1111/imj.16078

Genetic susceptibility to EBV-related disease

Gandhi, Maher K. (2023). Genetic susceptibility to EBV-related disease. Blood, 141 (13), 1499-1500. doi: 10.1182/blood.2022019180

EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort

Agrawal, Prashasti, David, Kevin A., Chen, Zhengming, Sundaram, Suchitra, Kim, Seo-Hyun, Vaca, Ryan, Lin, Yong, Singer, Samuel, Malecek, Mary-Kate, Carter, Jordan, Zayac, Adam, Kim, Myung Sun, Reddy, Nishitha, Ney, Douglas, Habib, Alma, Strouse, Christopher, Graber, Jerome, Bachanova, Veronika, Salman, Sidra, Vendiola, Jean A., Hossain, Nasheed, Tsang, Mazie, Major, Ajay, Gandhi, Maher K., Keane, Colm, Bond, David A., Folstad, Matthew, Chang, Julie, Mier-Hicks, Angel ... Martin, Peter (2023). EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort. Leukemia and Lymphoma, 64 (5), 1026-1034. doi: 10.1080/10428194.2023.2191152

Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: A Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study

Trotman, Judith, Presgrave, Peter, Carradice, Duncan P., Lenton, Douglas Stuart, Gandhi, Maher K., Cochrane, Tara, Badoux, Xavier, Carlson, Julia, Nkhoma, Gloria, Butcher, Belinda, Nikpour, Armin, Fulham, Michael and Johnston, Anna M. (2023). Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: A Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study. HemaSphere, 7 (3), e836. doi: 10.1097/HS9.0000000000000836

Inhibition of CD39 unleashes macrophage antibody-dependent cellular phagocytosis against B-cell lymphoma

Casey, Mika, Segawa, Kane, Law, Soi Cheng, Sabdia, Muhamamed Bilal, Nowlan, Bianca, Salik, Basit, Lee, Carol, Winterford, Clay, Pearson, Sally, Madore, Jason, Dougall, William C., Gandhi, Maher K. and Nakamura, Kyohei (2023). Inhibition of CD39 unleashes macrophage antibody-dependent cellular phagocytosis against B-cell lymphoma. Leukemia, 37 (2), 379-387. doi: 10.1038/s41375-022-01794-9

Crebbp mutations are associated with shorter time to progression in limited-stage follicular lymphoma treated with radiation

Hershenfeld, Samantha A., Shelton, Victoria, Bakhtiari, Mehran, Calvente, Lourdes, Lajkosz, Katherine, Isaev, Keren, Silva, Anjali, Liu, Ting, Brodtkorb, Marianne, d'Amore, Francesco Annibale, Ludvigsen, Maja, Madsen, Charlotte, Hamilton-Dutoit, Stephen, Gandhi, Maher, Tobin, Joshua W.D., Baetz, Tara, LeBrun, David, Johnson, Nathalie A., Mungall, Andrew J., Crump, Michael, Delabie, Jan, Gospodarowicz, Mary, Hodgson, David, Hong, Michael, Kukreti, Vishal, Kuruvilla, John, Prica, Anca, Tremblay-Lemay, Rosemarie, Tsang, Richard and Kridel, Robert (2022). Crebbp mutations are associated with shorter time to progression in limited-stage follicular lymphoma treated with radiation. Blood, 140 (S1), 3532-3533. doi: 10.1182/blood-2022-156571

The PO4-tential for less toxic CAR T-cell therapies

Tobin, Joshua W.D., Green, Michael R. and Gandhi, Maher K. (2022). The PO4-tential for less toxic CAR T-cell therapies. Cancer Immunology Research, 10 (12), 1422-1422. doi: 10.1158/2326-6066.cir-22-0793

Improving outcomes for patients with lymphoma: design and development of the Australian and New Zealand Lymphoma and Related Diseases Registry

Lymphoma and Related Diseases Registry Investigators, Gandhi, Maher K. and Keane, Colm (2022). Improving outcomes for patients with lymphoma: design and development of the Australian and New Zealand Lymphoma and Related Diseases Registry. BMC Medical Research Methodology, 22 (1) 266, 1-10. doi: 10.1186/s12874-022-01728-0

CD4 T Cells: the complicated key to unlocking the immune environment of classical Hodgkin Lymphoma

Gandhi, Maher K and Keane, Colm (2022). CD4 T Cells: the complicated key to unlocking the immune environment of classical Hodgkin Lymphoma. Haematologica, 108 (4), 1-3. doi: 10.3324/haematol.2022.281440

Neoantigens: the next frontier in precision immunotherapy for B-cell lymphoproliferative disorders

Sabdia, Muhammed B., Patch, Ann-Marie, Tsang, Hennes and Gandhi, Maher K. (2022). Neoantigens: the next frontier in precision immunotherapy for B-cell lymphoproliferative disorders. Blood Reviews, 56 100969, 100969. doi: 10.1016/j.blre.2022.100969

Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma

Ma, Man Chun John, Tadros, Saber, Bouska, Alyssa, Heavican, Tayla, Yang, Haopeng, Deng, Qing, Moore, Dalia, Akhter, Ariz, Hartert, Keenan, Jain, Neeraj, Showell, Jordan, Ghosh, Sreejoyee, Street, Lesley, Davidson, Marta, Carey, Christopher, Tobin, Joshua, Perumal, Deepak, Vose, Julie M., Lunning, Matthew A., Sohani, Aliyah R., Chen, Benjamin J., Buckley, Shannon, Nastoupil, Loretta J., Davis, R. Eric, Westin, Jason R., Fowler, Nathan H., Parekh, Samir, Gandhi, Maher, Neelapu, Sattva ... Green, Michael R. (2022). Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma. Haematologica, 107 (3), 690-701. doi: 10.3324/haematol.2020.274258

Immunity reloaded: deconstruction of the PD-1 axis in B cell lymphomas

Bednarska, Karolina, Nath, Karthik, Nicol, William and Gandhi, Maher K. (2021). Immunity reloaded: deconstruction of the PD-1 axis in B cell lymphomas. Blood Reviews, 50 100832, 100832. doi: 10.1016/j.blre.2021.100832

Intratumoral T‐cell receptor repertoire is predictive of interim PET scan results in patients with diffuse large B‐cell lymphoma treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R‐CHOP) chemoimmunotherapy

Shanavas, Mohamed, Law, Soi‐Cheng, Hertzberg, Mark, Hicks, Rodney J., Seymour, John F., Li, Zhixiu, Merida de Long, Lilia, Nath, Karthik, Sabdia, Muhammed B., Gunawardana, Jay, Gandhi, Maher K. and Keane, Colm (2021). Intratumoral T‐cell receptor repertoire is predictive of interim PET scan results in patients with diffuse large B‐cell lymphoma treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R‐CHOP) chemoimmunotherapy. Clinical and Translational Immunology, 10 (11) e1351, e1351. doi: 10.1002/cti2.1351

Characterisation of immune checkpoints in Richter syndrome identifies LAG3 as a potential therapeutic target

Gould, Clare, Lickiss, Jennifer, Kankanige, Yamuna, Yerneni, Satwica, Lade, Stephen, Gandhi, Maher K., Chin, Collin, Yannakou, Costas K., Villa, Diego, Slack, Graham W., Markham, John F., Tam, Constantine S., Nelson, Niles, Seymour, John F., Dickinson, Michael, Neeson, Paul J., Westerman, David and Blombery, Piers (2021). Characterisation of immune checkpoints in Richter syndrome identifies LAG3 as a potential therapeutic target. British Journal of Haematology, 195 (1) bjh.17789, 113-118. doi: 10.1111/bjh.17789

Intratumoral T cells have a differential impact on FDG-PET parameters in follicular lymphoma

Nath, Karthik, Law, Soi-Cheng, Sabdia, Muhammed B., Gunawardana, Jay, de Long, Lilia M., Sester, David, Shanavas, Mohamed, Tsang, Hennes, Tobin, Joshua W. D., Halliday, Sarah-Jane, Hernandez, Annette, Cross, Donna, Bird, Robert J., Jain, Sanjiv, Keane, Colm, Talaulikar, Dipti, Trotman, Judith, Law, Phillip and Gandhi, Maher K. (2021). Intratumoral T cells have a differential impact on FDG-PET parameters in follicular lymphoma. Blood Advances, 5 (12), 2644-2649. doi: 10.1182/bloodadvances.2020004051

Successful treatment of Epstein–Barr virus–associated primary central nervous system lymphoma due to post‐transplantation lymphoproliferative disorder, with ibrutinib and third‐party Epstein–Barr virus–specific T cells

Law, Soi C., Hoang, Thanh, O'Rourke, Kacey, Tobin, Joshua W. D., Gunawardana, Jay, Loo‐Oey, Dorothy, Bednarska, Karolina, Merida de Long, Lilia, Sabdia, Muhammed B., Hapgood, Greg, Blyth, Emily, Clancy, Leighton, Hennig, Stefanie, Keane, Colm and Gandhi, Maher K. (2021). Successful treatment of Epstein–Barr virus–associated primary central nervous system lymphoma due to post‐transplantation lymphoproliferative disorder, with ibrutinib and third‐party Epstein–Barr virus–specific T cells. American Journal of Transplantation, 21 (10) ajt.16628, 3465-3471. doi: 10.1111/ajt.16628

Discordant solutions to discordant problems

Tobin, Joshua W. D. and Gandhi, Maher K. (2021). Discordant solutions to discordant problems. Blood, 137 (21), 2857-2858. doi: 10.1182/blood.2021011362

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity

Gandhi, Maher K., Hoang, Thanh, Law, Soi C., Brosda, Sandra, O'Rourke, Kacey, Tobin, Joshua W. D., Vari, Frank, Murigneux, Valentine, Fink, J. Lynn, Gunawardana, Jay, Gould, Clare M., Oey, Harald, Bednarska, Karolina, Delecluse, Susanne, Trappe, Ralf Ulrich, de Long, Lilia Merida, Sabdia, Muhammed Bilal, Bhagat, Govind, Hapgood, Greg, Blyth, Emily, Clancy, Leighton E., Wight, Joel, Hawkes, Eliza A., Rimsza, Lisa M., Maguire, Alanna, Bojarczuk, Kamil, Chapuy, Bjoern and Keane, Colm (2021). EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity. Blood, 137 (11), 1468-1477. doi: 10.1182/blood.2020008520

Ibrutinib for central nervous system lymphoma: the Australasian Lymphoma Alliance/MD Anderson Cancer Center experience

Lewis, Katharine L., Chin, Collin K., Manos, Kate, Casey, John, Hamad, Nada, Crawford, Julie, Ho, Shir-Jing, Issa, Samar, Grigg, Andrew, Wood, Peter, Gandhi, Maher K., Do, Bryan, Nastoupil, Loretta, Hawkes, Eliza A. and Cheah, Chan Y. (2021). Ibrutinib for central nervous system lymphoma: the Australasian Lymphoma Alliance/MD Anderson Cancer Center experience. British Journal of Haematology, 192 (6) bjh.16946, 1049-1053. doi: 10.1111/bjh.16946

Targeted treatment of follicular lymphoma

Nath, Karthik and Gandhi, Maher K. (2021). Targeted treatment of follicular lymphoma. Journal of Personalized Medicine, 11 (2) 152, 1-22. doi: 10.3390/jpm11020152

A cost-effectiveness analysis of front-line treatment strategies in early-stage follicular lymphoma

Tobin, Joshua W. D., Crothers, Anna, Ma, Ti Eric, Mollee, Peter, Gandhi, Maher K., Scuffham, Paul and Hapgood, Greg (2021). A cost-effectiveness analysis of front-line treatment strategies in early-stage follicular lymphoma. Leukemia and Lymphoma, 62 (14), 1-9. doi: 10.1080/10428194.2021.1957866

Tumor microenvironment of follicular lymphoma

Nath, Karthik, Tsang, Hennes and Gandhi, Maher K. (2021). Tumor microenvironment of follicular lymphoma. Annals of Lymphoma, 5, 1-19. doi: 10.21037/aol-20-55

Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment

Kobayashi, Takumi, Lam, Pui Yeng, Jiang, Hui, Bednarska, Karolina, Gloury, Renee Elyse, Murigneux, Valentine, Tay, Joshua, Jacquelot, Nicolas, Li, Rui, Tuong, Zewen Kelvin, Leggatt, Graham, Gandhi, Maher K., Hill, Michelle M, Belz, Gabrielle T., Ngo, Shyuan, Kallies, Axel and Mattarollo, Stephen R. (2020). Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment. Blood, 136 (26), 3004-3017. doi: 10.1182/blood.2020005602

DA-EPOCH-R in Burkitt Lymphoma: Is it enough for high-risk disease?

Hertzberg, Mark, Joske, David J. L. and Gandhi, Maher K. (2020). DA-EPOCH-R in Burkitt Lymphoma: Is it enough for high-risk disease?. Journal of Clinical Oncology, 38 (31), 3722-3723. doi: 10.1200/jco.20.01850

Genetic aberrations of NLRC5 are associated with downregulated MHC‐I antigen presentation and impaired T‐cell immunity in follicular lymphoma

Gunawardana, Jay, Lee, Justina N., Bednarska, Karolina, Murigneux, Valentine, Long, Lilia Merida, Sabdia, Muhammed B., Birch, Simone, Tobin, Joshua W. D. and Gandhi, Maher K. (2020). Genetic aberrations of NLRC5 are associated with downregulated MHC‐I antigen presentation and impaired T‐cell immunity in follicular lymphoma. eJHaem, 1 (2) jha2.116, 517-526. doi: 10.1002/jha2.116

Risk‐adapted therapy in follicular lymphoma: is it time to FLEX ?

Tobin, Joshua W. D. and Gandhi, Maher K. (2020). Risk‐adapted therapy in follicular lymphoma: is it time to FLEX ?. American Journal of Hematology, 95 (12) ajh.26016, 1454-1456. doi: 10.1002/ajh.26016

Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma

Bararia, Deepak, Hildebrand, Johannes A., Stolz, Sebastian, Haebe, Sarah, Alig, Stefan, Trevisani, Christopher P., Osorio-Barrios, Francisco, Bartoschek, Michael D., Mentz, Michael, Pastore, Alessandro, Gaitzsch, Erik, Heide, Michael, Jurinovic, Vindi, Rautter, Katharina, Gunawardana, Jay, Sabdia, Muhammed B., Szczepanowski, Monika, Richter, Julia, Klapper, Wolfram, Louissaint, Abner, Ludwig, Christina, Bultmann, Sebastian, Leonhardt, Heinrich, Eustermann, Sebastian, Hopfner, Karl-Peter, Hiddemann, Wolfgang, von Bergwelt-Baildon, Michael, Steidl, Christian, Kridel, Robert ... Weigert, Oliver (2020). Cathepsin S alterations induce a tumor-promoting immune microenvironment in follicular lymphoma. Cell Reports, 31 (5) 107522, 107522. doi: 10.1016/j.celrep.2020.107522

LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma

Keane, Colm, Law, Soi C., Gould, Clare, Birch, Simone, Sabdia, Muhammed B., Merida de Long, Lilia, Thillaiyampalam, Gayathri, Abro, Emad, Tobin, Joshua W., Tan, Xiaohong, Xu-Monette, Zijun Y., Young, Ken H., Gifford, Grace, Gabreilli, Sara, Stevenson, William S., Gill, Anthony, Talaulikar, Dipti, Jain, Sanjiv, Hernandez, Annette, Halliday, Sarah-Jane, Bird, Robert, Cross, Donna, Hertzberg, Mark and Gandhi, Maher K. (2020). LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma. Blood Advances, 4 (7), 1367-1377. doi: 10.1182/bloodadvances.2019001390

Reply to M. Sorigue

Tobin, Joshua W.D., Keane, Colm, Gunawardana, Jay and Gandhi, Maher K. (2020). Reply to M. Sorigue. Journal of Clinical Oncology, 38 (6), 648-649. doi: 10.1200/JCO.19.02935

Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibody

Nakamura, Kyohei, Casey, Mika, Oey, Harald, Vari, Frank, Stagg, John, Gandhi, Maher K. and Smyth, Mark J. (2020). Targeting an adenosine-mediated “don’t eat me signal” augments anti-lymphoma immunity by anti-CD20 monoclonal antibody. Leukemia, 34 (10), 2708-2721. doi: 10.1038/s41375-020-0811-3

EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2

Cristino, Alexandre S., Nourse, Jamie, West, Rachael A., Sabdia, Muhammed Bilal, Law, Soi C., Gunawardana, Jay, Vari, Frank, Mujaj, Sally, Thillaiyampalam, Gayathri, Snell, Cameron, Gough, Madeline, Keane, Colm and Gandhi, Maher K. (2019). EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2. Blood, 134 (25), 2261-2270. doi: 10.1182/blood.2019000889

Outcomes of stage I/II follicular lymphoma in the PET era: an international study from the Australian Lymphoma Alliance

Tobin, Joshua W. D., Rule, Gabrielle, Colvin, Katherine, Calvente, Lourdes, Hodgson, David, Bell, Stephen, Dunduru, Chengetai, Gallo, James, Tsang, Erica S., Tan, Xuan, Wong, Jonathan, Pearce, Jessica, Campbell, Robert, Tneh, Shao, Shorten, Sophie, Ng, Melissa, Cochrane, Tara, Tam, Constantine S., Abro, Emad, Hawkes, Eliza, Hodges, Georgina, Kansara, Roopesh, Talaulikar, Dipti, Gilbertson, Michael, Johnston, Anna M., Savage, Kerry J., Villa, Diego, Morris, Kirk, Ratnasingam, Sumi ... Hapgood, Greg (2019). Outcomes of stage I/II follicular lymphoma in the PET era: an international study from the Australian Lymphoma Alliance. Blood Advances, 3 (19), 2804-2811. doi: 10.1182/bloodadvances.2019000458

The tumour microenvironment is immuno‐tolerogenic and a principal determinant of patient outcome in EBV‐positive diffuse large B‐cell lymphoma

Keane, Colm, Tobin, Joshua, Gunawardana, Jay, Francis, Santiyagu, Gifford, Grace, Gabrielli, Sara, Gill, Anthony, Stevenson, William, Talaulikar, Dipti, Gould, Clare, Jain, Sanjiv, Birch, Simone, Hertzberg, Mark and Gandhi, Maher K. (2019). The tumour microenvironment is immuno‐tolerogenic and a principal determinant of patient outcome in EBV‐positive diffuse large B‐cell lymphoma. European Journal of Haematology, 103 (3) ejh.13274, 200-207. doi: 10.1111/ejh.13274

Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration

Tobin, Joshua W. D., Keane, Colm, Gunawardana, Jay, Mollee, Peter, Birch, Simone, Hoang, Thanh, Lee, Justina, Li, Li, Huang, Li, Murigneux, Valentine, Fink, J. Lynn, Matigian, Nicholas, Vari, Frank, Francis, Santiyagu, Kridel, Robert, Weigert, Oliver, Haebe, Sarah, Jurinovic, Vindi, Klapper, Wolfram, Steidl, Christian, Sehn, Laurie H., Law, Soi-Cheng, Wykes, Michelle N. and Gandhi, Maher K. (2019). Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration. Journal of Clinical Oncology, 37 (34), 3300-3309. doi: 10.1200/JCO.18.02365

COO and MYC/BCL2 status do not predict outcome among patients with stage I/II DLBCL: a retrospective multicenter study

Barraclough, Allison, Alzahrani, Musa, Ettrup, Marianne Schmidt, Bishton, Mark, van Vliet, Chris, Farinha, Pedro, Gould, Clare, Birch, Simone, Sehn, Laurie H., Sovani, Vishakha, Ward, Mitchell Steven, Augustson, Bradley, Biccler, Jorne, Connors, Joseph M., Scott, David W., Gandhi, Maher K., Savage, Kerry J., El-Galaly, Tarec, Villa, Diego and Cheah, Chan Yoon (2019). COO and MYC/BCL2 status do not predict outcome among patients with stage I/II DLBCL: a retrospective multicenter study. Blood Advances, 3 (13), 2013-2021. doi: 10.1182/bloodadvances.2019000251

Human peripheral blood DNAM-1neg NK cells are a terminally differentiated subset with limited effector functions

Stannard, Kimberley A., Lemoine, Sébastien, Waterhouse, Nigel J., Vari, Frank, Chatenoud, Lucienne, Gandhi, Maher K., Martinet, Ludovic, Smyth, Mark J. and Guillerey, Camille (2019). Human peripheral blood DNAM-1neg NK cells are a terminally differentiated subset with limited effector functions. Blood Advances, 3 (11), 1681-1694. doi: 10.1182/bloodadvances.2018030676

Biology and therapy of primary mediastinal B-cell lymphoma: current status and future directions

Lees, Charlotte, Keane, Colm, Gandhi, Maher K. and Gunawardana, Jay (2019). Biology and therapy of primary mediastinal B-cell lymphoma: current status and future directions. British Journal of Haematology, 185 (1), 25-41. doi: 10.1111/bjh.15778

Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies

Law, Soi Cheng, Haigh, Oscar L., Walpole, Carina M., Keane, Colm, Miles, John, Gandhi, Maher K., Radford, Kristen J. and Steptoe, Raymond J. (2019). Simple, rapid and inexpensive typing of common HLA class I alleles for immunological studies. Journal of Immunological Methods, 465, 72-76. doi: 10.1016/j.jim.2018.12.002

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker

Sina, Abu Ali Ibn, Carrascosa, Laura G., Liang, Ziyu, Grewal, Yadveer S., Wardiana, Andri, Shiddiky, Muhammad J. A., Gardiner, Robert A., Samaratunga, Hemamali, Gandhi, Maher K., Scott, Rodney J., Korbie, Darren and Trau, Matt (2018). Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker. Nature Communications, 9 (1) 4915, 4915. doi: 10.1038/s41467-018-07214-w

Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma

Cui, Qingyan, Vari, Frank, Cristino, Alexandre S., Salomon, Carlos, Rice, Gregory E., Sabdia, Muhammed B., Guanzon, Dominic, Palma, Carlos, Mathew, Marina, Talaulikar, Dipti, Jain, Sanjiv, Han, Erica, Hertzberg, Mark S., Gould, Clare, Crooks, Pauline, Thillaiyampalam, Gayathri, Keane, Colm and Gandhi, Maher K. (2018). Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large b-cell lymphoma. Oncotarget, 9 (78), 34644-34657. doi: 10.18632/oncotarget.26141

A high LDH to absolute lymphocyte count ratio in patients with DLBCL predicts for a poor intratumoral immune response and inferior survival

Keane, Colm, Tobin, Joshua, Talaulikar, Dipti, Green, Michael, Crooks, Pauline, Jain, Sanjiv and Gandhi, Maher (2018). A high LDH to absolute lymphocyte count ratio in patients with DLBCL predicts for a poor intratumoral immune response and inferior survival. OncoTarget, 9 (34), 23620-23627. doi: 10.18632/oncotarget.25306

Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S, Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone and Gandhi, Maher K (2018). Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL. Blood, 131 (16), 1809-1819. doi: 10.1182/blood-2017-07-796342

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

McKee, Sara J., Tuong, Zewen K., Kobayashi, Takumi, Doff, Brianna L., Soon, Megan S. F ., Nissen, Michael, Lam, Pui Yeng, Keane, Colm, Vari, Frank, Moi, Davide, Mazzieri, Roberta, Leggatt, Graham, Gandhi, Maher K. and Mattarollo, Stephen R. (2018). B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity. OncoImmunology, 7 (2) e1393599, e1393599. doi: 10.1080/2162402X.2017.1393599

The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma

Keane, Colm, Gould, Clare, Jones, Kimberley, Hamm, David, Talaulikar, Dipti, Ellis, Jonathan, Vari, Frank, Birch, Simone, Han, Erica, Wood, Peter, Le-Cao, Kim-Anh, Green, Michael R., Crooks, Pauline, Jain, Sanjiv, Tobin, Josh, Steptoe, Raymond J. and Gandhi, Maher K. (2017). The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma. Clinical Cancer Research, 23 (7), 1820-1828. doi: 10.1158/1078-0432.CCR-16-1576

Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14

Hertzberg, Mark, Gandhi, Maher K. , Trotman, Judith, Butcher, Belinda, Taper, John, Johnston, Amanda, Gill, Devinder, Ho, Shir-Jing, Cull, Gavin, Fay, Ketih, Chong, Geoff, Grigg, Andrew, Lewis, Ian D. , Milliken, Sam, Renwick, William, Hahn, Uwe, Filshie, Robin, Kannourakis, George, Watson, Anne-Marie, Warburton, Pauline, Wirth, Andrew, Seymour, John F. , Hofman, Michael S. and Hicks, Rodney J. (2017). Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14. Haematologica, 102 (2), 356-363. doi: 10.3324/haematol.2016.154039

Dielectrophoretic microfluidic chip enables single-cell measurements for multidrug resistance in heterogeneous acute myeloid leukemia patient samples

Khamenehfar, Avid, Gandhi, Maher K., Chen, Yuchun, Hogge, Donna E. and Li, Paul C. H. (2016). Dielectrophoretic microfluidic chip enables single-cell measurements for multidrug resistance in heterogeneous acute myeloid leukemia patient samples. Analytical Chemistry, 88 (11), 5680-5688. doi: 10.1021/acs.analchem.5b04446

Recent treatment advances in Hodgkin Lymphoma: a concise review

Arulogun, Suzanne, Hertzberg, Mark and Gandhi, Maher K. (2016). Recent treatment advances in Hodgkin Lymphoma: a concise review. Internal Medicine Journal, 46 (12), 1364-1369. doi: 10.1111/imj.13051

The impact of HLA class I and EBV latency-II antigen-specific CD8+ T cells on the pathogenesis of EBV+ Hodgkin lymphoma

Jones, K., Wockner, L., Brennan, R. M., Keane, C., Chattopadhyay, P. K., Roederer, M., Price, D. A., Cole, D. K., Hassan, B., Beck, K., Gottlieb, D., Ritchie, D. S., Seymour, J. F., Vari, F., Crooks, P., Burrows, S. R. and Gandhi, M. K. (2016). The impact of HLA class I and EBV latency-II antigen-specific CD8+ T cells on the pathogenesis of EBV+ Hodgkin lymphoma. Clinical and Experimental Immunology, 183 (2), 206-220. doi: 10.1111/cei.12716

Whole blood EBV-DNA: a surrogate for immune dysfunction in aggressive lymphoma?

Cui, Qingyan and Gandhi, Maher K. (2016). Whole blood EBV-DNA: a surrogate for immune dysfunction in aggressive lymphoma?. Leukemia and Lymphoma, 57 (3), 507-508. doi: 10.3109/10428194.2015.1087522

Cessation of immunosuppression during chemotherapy for post-transplant lymphoproliferative disorders in renal transplant patients

Taylor, Emma, Jones, Mark, Hourigan, Matthew J., Johnson, David W., Gill, Devinder S., Isbel, Nicole, Hawley, Carmel M., Marlton, Paula, Gandhi, Maher K., Campbell, Scott B. and Mollee, Peter (2015). Cessation of immunosuppression during chemotherapy for post-transplant lymphoproliferative disorders in renal transplant patients. Nephrology Dialysis Transplantation, 30 (10), 1774-1779. doi: 10.1093/ndt/gfv260

Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study

Keane, Colm, Vari, Frank, Hertzberg, Mark, Le Cao, Kim-Anh, Green, Michael R., Han, Erica, Seymour, John F., Hicks, Rodney J., Gill, Devinder, Crooks, Pauline, Gould, Clare, Jones, Kimberley, Griffiths, Lyn R., Talaulikar, Dipti, Jain, Sanjiv, Tobin, Josh and Gandhi, Maher K. (2015). Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study. Lancet Haematology, 2 (10), e445-e455. doi: 10.1016/S2352-3026(15)00150-7

Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing

Kurtz, David M., Green, Michael R., Bratman, Scott V., Scherer, Florian, Liu, Chih Long, Kunder, Christian A., Takahashi, Kazuhiro, Glover, Cynthia, Keane, Colm, Kihira, Shingo, Visser, Brendan, Callahan, Jason, Kong, Katherine A., Faham, Malek, Corbelli, Karen S., Miklos, David, Advani, Ranjana H., Levy, Ronald, Hicks, Rodney J., Hertzberg, Mark, Ohgami, Robert S., Gandhi, Maher K., Diehn, Maximilian and Alizadeh, Ash A. (2015). Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing. Blood, 125 (24), 3679-3687. doi: 10.1182/blood-2015-03-635169

HLA class I associations with EBV+ post-transplant lymphoproliferative disorder

Jones, Kimberley, Wockner, Leesa, Thornton, Alycia, Gottlieb, David, Ritchie, David S, Seymour, John F, Kumarasinghe, Gayathri and Gandhi, Maher K (2015). HLA class I associations with EBV+ post-transplant lymphoproliferative disorder. Transplant Immunology, 32 (2), 126-130. doi: 10.1016/j.trim.2015.02.005

Deregulated JAK/STAT signalling in lymphomagenesis, and its implications for the development of new targeted therapies

Scott, Linda M. and Gandhi, Maher K. (2015). Deregulated JAK/STAT signalling in lymphomagenesis, and its implications for the development of new targeted therapies. Blood Reviews, 29 (6), 405-415. doi: 10.1016/j.blre.2015.06.002

A comprehensive analysis of the cellular and EBV-Specific MicroRNAome in primary CNS PTLD identifies different patterns among EBV-associated tumors

Fink, S. E. K., Gandhi, M. K., Nourse, J. P., Keane, C., Jones, K., Crooks, P., Johrens, K., Korfel, A., Schmidt, H., Neumann, S., Tiede, A., Jager, U., Duhrsen, U., Neuhaus, R., Dreyling, M., Borchert, K., Sudhoff, T., Riess, H., Anagnostopoulos, I. and Trappe, R. U. (2014). A comprehensive analysis of the cellular and EBV-Specific MicroRNAome in primary CNS PTLD identifies different patterns among EBV-associated tumors. American Journal of Transplantation, 14 (11), 2577-2587. doi: 10.1111/ajt.12858

A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study)

Tran, Huyen, Brighton, Tim, Grigg, Andrew, McRae, Simon, Dixon, Joanna, Thurley, Daniel, Gandhi, Maher K., Truman, Matt, Marlton, Paula and Catalano, John (2014). A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study). British Journal of Haematology, 167 (2), 243-251. doi: 10.1111/bjh.13029

In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin’s lymphoma (NHL)

Aya-Bonilla, Carlos, Camilleri, Emily, Haupt, Larisa M., Lea, Rod, Gandhi, Maher K. and Griffiths, Lyn R. (2014). In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin’s lymphoma (NHL). BMC Genomics, 15 (390) 390, 1-12. doi: 10.1186/1471-2164-15-390

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia

Seymour, L. A., Nourse, J. P., Crooks, P., Wockner, L., Bird, R., Tran, H. and Gandhi, M. K. (2014). The presence of KIR2DS5 confers protection against adult immune thrombocytopenia. Tissue Antigens, 83 (3), 154-160. doi: 10.1111/tan.12295

FCY-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive post-transplant lymphoproliferative disorder

Zimmermann, Heiner, Weiland, Theresa, Nourse, Jamie P., Gandhi, Maher K., Reinke, Petra, Neuhaus, Ruth, Karbasiyan, Mohsen, Gärtner, Barbara, Anagnostopoulos, Ioannis, Riess, Hanno, Trappe, Ralf and Oertel, Stephan (2014). FCY-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive post-transplant lymphoproliferative disorder. Journal of Immunology Research, 264723 264723, 1-6. doi: 10.1155/2014/264723

A new frontier in haematology - combining pharmacokinetic with pharmacodynamic factors to improve choice and dose of drug

Arpon, David Rey, Gandhi, Maher K. and Martin, Jennifer H. (2014). A new frontier in haematology - combining pharmacokinetic with pharmacodynamic factors to improve choice and dose of drug. British Journal of Clinical Pharmacology, 78 (2), 274-281. doi: 10.1111/bcp.12318

Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma

Jones, Kimberley, Nourse, Jamie P., Keane, Colm, Bhatnagar, Atul and Gandhi, Maher K. (2014). Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma. Clinical Cancer Research, 20 (1), 253-264. doi: 10.1158/1078-0432.CCR-13-1024

CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy

Keane, Colm, Gill, Devinder, Vari, Frank, Cross, Donna, Griffiths, Lynn and Gandhi, Maher (2013). CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy. American Journal of Hematology, 88 (4), 273-276. doi: 10.1002/ajh.23398

Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma

Jones, Kimberley, Vari, Frank, Keane, Colm, Crooks, Pauline, Nourse, Jamie P., Seymour, Louise A., Gottlieb, David, Ritchie, David, Gill, Devinder and Gandhi, Maher K. (2013). Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma. Clinical Cancer Research, 19 (3), 731-742. doi: 10.1158/1078-0432.CCR-12-2693

High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma

Aya-Bonilla, C., Green, M.R., Camilleri, E., Benton, M., Keane, C., Marlton, P., Lea, R., Gandhi, M.K. and Griffiths, L.R. (2013). High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma. Genes Chromosomes and Cancer, 52 (5), 467-479. doi: 10.1002/gcc.22044

Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era

Evens A.M., Choquet S., Kroll-Desrosiers A.R., Jagadeesh D., Smith S.M., Morschhauser F., Leblond V., Roy R., Barton B., Gordon L.I., Gandhi M.K., Dierickx D., Schiff D., Habermann T.M. and Trappe R. (2013). Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era. American Journal of Transplantation, 13 (6), 1512-1522. doi: 10.1111/ajt.12211

The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1

Ross, Nathan, Gandhi, Maher K. and Nourse, Jamie P. (2013). The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1. American Journal of Blood Research, 3 (3), 210-224.

Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis

Vari, Frank and Gandhi, Maher K. (2012). Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis. Leukemia & Lymphoma, 53 (11), 2097-2098. doi: 10.3109/10428194.2012.701297

Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma

Keane, C., Nourse, J. P., Crooks, P., Nguyen-Van, D., Mutsando, H., Mollee, P., Lea, R. A. and Gandhi, M. K. (2012). Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma. Internal Medicine Journal, 42 (10), 1113-1119. doi: 10.1111/j.1445-5994.2011.02587.x

Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples

Nourse, J.P., Crooks, P., Keane, C.., Nguyen-Van, D., Mujaj, S., Ross, N., Jones, K., Vari, F., Han, E., Trappe, R., Fink, S. and Gandhi, M.K. (2012). Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples. Journal of Virological Methods, 184 (1-2), 46-54. doi: 10.1016/j.jviromet.2012.05.005

EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors

White, Robert E., Raemer, Patrick C., Naresh, Kikkeri N., Meixlsperger, Sonja, Pinaud, Laurie, Rooney, Cliona, Savoldo, Barbara, Coutinho, Rita, Boedoer, Csaba, Gribben, John, Ibrahim, Hazem A., Bower, Mark, Nourse, Jamie P., Gandhi, Maher K., Middeldorp, Jaap, Cader, Fathima Z., Murray, Paul, Muenz, Christian and Allday, Martin J. (2012). EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors. Journal of Clinical Investigation, 122 (4), 1487-1502. doi: 10.1172/JCI58092

Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma

Jones, Kimberley, Nourse, Jamie P., Keane, Colm, Crooks, Pauline, Gottlieb, David, Ritchie, David S., Gill, Devinder and Gandhi, Maher K. (2012). Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma. American Journal of Hematology, 87 (3), 258-265. doi: 10.1002/ajh.22252

High dose methotrexate and extended hours high-flux hemodialysis for the treatment of primary central nervous system lymphoma in a patient with end stage renal disease

Mutsando, Howard, Fahim, Magid, Gill, Devinder S., Hawley, Carmel M., Johnson, David W., Maher, K. Gandhi, Marlton, Paula V., Mar Fan, Helen G. and Mollee, Peter N. (2012). High dose methotrexate and extended hours high-flux hemodialysis for the treatment of primary central nervous system lymphoma in a patient with end stage renal disease. American Journal of Blood Research, 2 (1), 66-70.

The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms

Nourse, Jamie P., Lea, Rod, Crooks, Pauline, Wright, Gillian, Tran, Huyen, Catalano, John, Brighton, Tim, Grigg, Andrew, Marlton, Paula and Gandhi, Maher K. (2012). The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms. Blood Coagulation and Fibrinolysis, 23 (1), 45-50. doi: 10.1097/MBC.0b013e32834d7ce3

A novel immunodeficiency disorder characterized by genetic amplification of interleukin 25

Green, M. R., Camilleri, E., Gandhi, M. K., Peake, J. and Griffiths, L. R. (2011). A novel immunodeficiency disorder characterized by genetic amplification of interleukin 25. Genes and Immunity, 12 (8), 663-666. doi: 10.1038/gene.2011.50

Optimizing tumor-targeting chimeric antigen receptor T cells in B-cell lymphoma patients

Gandhi, M. and Jones, K. (2011). Optimizing tumor-targeting chimeric antigen receptor T cells in B-cell lymphoma patients. Immunotherapy, 3 (12), 1441-1443. doi: 10.2217/IMT.11.135

Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly expresses EBNA3A with conserved CD8 T-cell epitopes

Nguyen-Van, Do, Keane, Colm, Han, Erica, Jones, Kimberley, Nourse, Jamie P., Vari, Frank, Ross, Nathan, Crooks, Pauline, Ramuz, Olivier, Green, Michael, Griffith, Lyn, Trappe, Ralf, Grigg, Andrew, Mollee, Peter and Gandhi, Maher K. (2011). Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly expresses EBNA3A with conserved CD8 T-cell epitopes. American Journal of Blood Research, 1 (2), 146-159.

Broad-spectrum immunosuppression by classless monocytes in non-Hodgkin's lymphoma

Vari, F. and Gandhi, M.K. (2011). Broad-spectrum immunosuppression by classless monocytes in non-Hodgkin's lymphoma. Immunotherapy, 3 (6), 723-726. doi: 10.2217/IMT.11.56

Molecular mechanisms influencing NK cell development: implications for NK cell malignancies.

Mujaj, Sally A., Spanevello, Michelle M., Gandhi, Maher K. and Nourse, Jamie P. (2011). Molecular mechanisms influencing NK cell development: implications for NK cell malignancies.. American Journal of Blood Research, 1 (1), 34-45.

Epstein-Barr virus-related post-transplant lymphoproliferative disorders: Pathogenetic insights for targeted therapy

Nourse, J. P., Jones, K. and Gandhi, M. K. (2011). Epstein-Barr virus-related post-transplant lymphoproliferative disorders: Pathogenetic insights for targeted therapy. American Journal of Transplantation, 11 (5), 888-895. doi: 10.1111/j.1600-6143.2011.03499.x

Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non-Hodgkin's lymphoma

Green, Michael R., Aya-Bonilla, Carlos, Gandhi, Maher K., Lea, Rod A., Wellwood, Jeremy, Wood, Peter, Marlton, Paula and Griffiths, Lyn R. (2011). Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non-Hodgkin's lymphoma. Genes Chromosomes and Cancer, 50 (5), 313-326. doi: 10.1002/gcc.20856

Expansion of EBNA1-specific effector T cells in posttransplantation lymphoproliferative disorders

Jones, Kimberley, Nourse, Jamie P., Morrison, Leanne, Nguyen-Van, Do, Moss, Denis J., Burrows, Scott R. and Gandhi, Maher K. (2010). Expansion of EBNA1-specific effector T cells in posttransplantation lymphoproliferative disorders. Blood, 116 (13), 2245-2252. doi: 10.1182/blood-2010-03-274076

Can a blood test monitor lymphoma?

Jones, Kimberley and Gandhi, Maher K. (2010). Can a blood test monitor lymphoma?. Leukemia and Lymphoma, 51 (6), 957-959. doi: 10.3109/10428194.2010.487623

Fulminant infectious mononucleosis and recurrent epstein-barr virus reactivation in an adolescent

Nourse, Jamie P., Jones, Kimberley, Dua, Ujjwal, Runnegar, Naomi, Looke, David, Schmidt, Chris, Tey, Siok-Keen, Kennedy, Glen and Gandhi, Maher K. (2010). Fulminant infectious mononucleosis and recurrent epstein-barr virus reactivation in an adolescent. Clinical Infectious Diseases, 50 (6), e34-e37. doi: 10.1086/650007

Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity

Jones, K., Nourse, J., Corbett, G. and Gandhi, M. K. (2010). Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity. International Journal of Laboratory Hematology, 32 (1p1), e169-e174. doi: 10.1111/j.1751-553X.2008.01130.x

Selective accumulation of virus-specific CD8(+) T cells within the peripheral blood stem cell compartment

Singh, Sanjleena, van Hauten, Paulien, Jones, Kimberley, Grimmett, Karen, Mills, Anthony K. and Gandhi, Maher K. (2009). Selective accumulation of virus-specific CD8(+) T cells within the peripheral blood stem cell compartment. Blood, 114 (9), 2001-2003. doi: 10.1182/blood-2009-05-221267

Epstein-Barr virus DNA as a biomarker for Epstein-Barr virus-positive lymphomas: Are we there yet?

Jones, Kimberley and Gandhi, Maher K. (2009). Epstein-Barr virus DNA as a biomarker for Epstein-Barr virus-positive lymphomas: Are we there yet?. Leukemia and Lymphoma, 50 (5), 684-686. doi: 10.1080/10428190902847716

High levels of BACH2 associated with lower levels of BCL2 transcript abundance in t(14;18)(q21;q34) translocation positive non-Hodgkin's lymphoma

Green, Michael, Gandhi, Maher K, Camilleri, Emily, Marlton, Paula, Lea, Rod and Griffiths, Lyn (2009). High levels of BACH2 associated with lower levels of BCL2 transcript abundance in t(14;18)(q21;q34) translocation positive non-Hodgkin's lymphoma. Leukemia Research, 33 (5), 731-734. doi: 10.1016/j.leukres.2008.09.007

What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?

Gandhi, Maher K. (2009). What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?. Medical Journal of Australia, 190 (8), 461-461.

The role of Epstein-Barr virus in Richter syndrome

Nourse, Jamie, Jones, Kimberley and Gandhi, Maher K. (2009). The role of Epstein-Barr virus in Richter syndrome. British Journal of Haematology, 144 (4), 613-613. doi: 10.1111/j.1365-2141.2008.07471.x

Relative abundance of full-length and truncated FOXP1 isoforms is associated with differential NF kappa B activity in Follicular Lymphoma

Green, Michael R., Gandhi, Maher K., Courtney, Mark J., Marlton, Paula and Griffiths, Lyn (2009). Relative abundance of full-length and truncated FOXP1 isoforms is associated with differential NF kappa B activity in Follicular Lymphoma. Leukemia Research, 33 (12), 1699-1702. doi: 10.1016/j.leukres.2009.05.004

Immunodeficiency-associated lymphomas

Tran, Huy, Nourse, Jamie, Hall, Sara, Green, Michael, Griffiths, Lyn and Gandhi, Maher K. (2008). Immunodeficiency-associated lymphomas. Blood Reviews, 22 (5), 261-281. doi: 10.1016/j.blre.2008.03.009

A new prognosticator for post-transplant lymphoproliferative disorders after renal transplantation

Hourigan, Matthew J., Doecke, James, Mollee, Peter N., Gill, Devinder S., Norris, Debra, Johnson, David W. and Gandhi, Maher K. (2008). A new prognosticator for post-transplant lymphoproliferative disorders after renal transplantation. British Journal of Haematology, 141 (6), 904-907. doi: 10.1111/j.1365-2141.2008.07149.x

Methotrexate-associated mantle-cell lymphoma in an elderly man with myasthenia gravis

Tran, Huy, Cheung, Catherine, Gill, Devinder, Dua, Ujjwal, Nourse, Jamie, Boyle, Richard and Gandhi, Maher K. (2008). Methotrexate-associated mantle-cell lymphoma in an elderly man with myasthenia gravis. Nature Clinical Practice Oncology, 5 (4), 234-238. doi: 10.1038/ncponc1071

Immunity, homing and efficacy of allogeneic adoptive immunotherapy for posttransplant lymphoproliferative disorders

Gandhi, M., Wilkie, G. M., Dua, U., Mollee, P., Grimmett, K., Williams, T., Whitaker, N., Gill, D. and Crawford, D. (2007). Immunity, homing and efficacy of allogeneic adoptive immunotherapy for posttransplant lymphoproliferative disorders. American Journal of Transplantation, 7 (5), 1293-1299. doi: 10.1111/j.1600-6143.2007.01796.x

Epstein-Barr virus T-cell immunity despite rituximab

Nehring, Angela K., Dua, Ujjwal, Mollee, Peter, Gill, Devinder, Grimmett, Karen, Khanna, Rajiv, Moss, Denis and Gandhi, Maher K. (2007). Epstein-Barr virus T-cell immunity despite rituximab. British Journal of Haematology, 136 (4), 628-632. doi: 10.1111/j.1365-2141.2006.06482.x

Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial

Haque, T., Wilkie, G., Jones, M., Higgins, C., Urquhart, G., Wingate, P., Burns, D., McAulay, K., Turner, M., Bellamy, C., Amlot, P., Kelly, D., MacGilchrist, A., Gandhi, M., Swerdlow A. and Crawford, D. (2007). Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial. Blood, 110 (4), 1123-1131. doi: 10.1182/blood-2006-12-063008

Galectin-1 mediated suppression of Epstein-Barr virus-specific T-cell immunity in classic Hodgkin lymphoma

Gandhi, Maher K., Moll, Guido, Smith, Corey, Dua, Ujjwal, Lambley, Eleanore, Ramuz, Olivier, Gill, Devinder, Marlton, Paula, Seymour, John F. and Khanna, Rajiv (2007). Galectin-1 mediated suppression of Epstein-Barr virus-specific T-cell immunity in classic Hodgkin lymphoma. Blood, 110 (4), 1326-1329. doi: 10.1182/blood-2007-01-066100

The International Prognostic Index: the “gold-standard” in post-transplant lymphoproliferative disorders after renal transplantation

Hourigan, M. J., Mollee, P. N., Gill, D. S., Doecke, J., Norris, D., Johnson, D. W. and Gandhi, M. K.. (2007). The International Prognostic Index: the “gold-standard” in post-transplant lymphoproliferative disorders after renal transplantation. American Journal of Transplantation, 7, 399-399.

The use of T-cell directed cellular therapies in Australia

Moss, D.J., Khanna, R. and Gandhi, M. (2007). The use of T-cell directed cellular therapies in Australia. Cytotherapy, 9 (3), 222-224. doi: 10.1080/14653240701320288

Functional reversion of antigen-specific CD8(+) T cells from patients with Hodgkin lymphoma following in vitro stimulation with recombinant polyepitope

Smith, Corey, Cooper, Leanne, Burgess, Melinda, Rist, Michael, Webb, Natasha, Lambley, Eleanore, Tellam, Judy, Marlton, Paula, Seymour, John F., Gandhi, Maher and Khanna, Rajiv (2006). Functional reversion of antigen-specific CD8(+) T cells from patients with Hodgkin lymphoma following in vitro stimulation with recombinant polyepitope. Journal of Immunology, 177 (7), 4897-4906. doi: 10.4049/jimmunol.177.7.4897

Epstein-Barr virus and advanced chronic lymphocytic leukemia: innocent until proven guilty?

Gandhi, Maher and Khanna, Rajiv (2006). Epstein-Barr virus and advanced chronic lymphocytic leukemia: innocent until proven guilty?. Leukemia and Lymphoma, 47 (5), 779-780. doi: 10.1080/10428190600580973

Epstein-Barr virus and advanced chronic lymphocytic leukemia: innocent until proven guilty? Commentary on: Tsimberidou et al. Epstein-Barr virus in patients with chronic lymphocytic leukemia: A pilot study. Leuk Lymphoma 2006; 47 : 827-836

Gandhi, M and Khanna, R (2006). Epstein-Barr virus and advanced chronic lymphocytic leukemia: innocent until proven guilty? Commentary on: Tsimberidou et al. Epstein-Barr virus in patients with chronic lymphocytic leukemia: A pilot study. Leuk Lymphoma 2006; 47 : 827-836. Leukemia & Lymphoma, 47 (5), 779-780. doi: 10.1080/10428190600580973

Correlation of T-cell immune response with spontaneous resolution and subsequent relapse of Hodgkin's lymphoma

Wilson, W. M., Dua, U., Grigg, A. P. and Gandhi, M. K. (2006). Correlation of T-cell immune response with spontaneous resolution and subsequent relapse of Hodgkin's lymphoma. Leukemia & Lymphoma, 47 (5), 871-876. doi: 10.1080/10428190600649562

Epstein-Barr virus-associated lymphomas

Gandhi, M. K. (2006). Epstein-Barr virus-associated lymphomas. Expert Review of Anti-Infective Therapy, 4 (1), 77-89. doi: 10.1586/14737140.4.1.77

Expression of LAG-3 by tumor-infiltrating lymphocytes is coincident with the suppression of latent membrane antigen-specific CD8(+) T-cell function in Hodgkin lymphoma patients

Gandhi, M. K., Lambley, E., Duraiswamy, J., Dua, U., Smith, C., Elliott, S., Gill, D., Marlton, P., Seymour, J. and Khanna, R. (2006). Expression of LAG-3 by tumor-infiltrating lymphocytes is coincident with the suppression of latent membrane antigen-specific CD8(+) T-cell function in Hodgkin lymphoma patients. Blood, 108 (7), 2280-2289. doi: 10.1182/blood-2006-04-015164

Plasma Epstein-Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin's lymphoma

Gandhi, M. K., Lambley, E., Burrows, J., Dua, U., Elliott, S., Shaw, P. J., Prince, H. M., Wolf, M., Clarke, K., Underhill, C., Mills, T., Mollee, P., Gill, D., Marlton, P., Seymour, J. F. and Khanna, R. (2006). Plasma Epstein-Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin's lymphoma. Clinical Cancer Research, 12 (2), 460-464. doi: 10.1158/1078-0432.CCR-05-2008

Viruses and lymphoma

Gandhi, Maher K. and Khanna, Rajiv (2005). Viruses and lymphoma. Pathology, 37 (6), 420-433. doi: 10.1080/003130200500368303

Follicular lymphoma: Time for a re-think?

Gandhi, Maher K. and Marcus, Robert E. (2005). Follicular lymphoma: Time for a re-think?. Blood Reviews, 19 (3), 165-178. doi: 10.1016/j.blre.2004.09.001

Regulation of clinical research

Gandhi, Maher K. (2005). Regulation of clinical research. Clinical Medicine, 5 (3), 299-299. doi: 10.7861/clinmedicine.5-3-299

Technology Insight: Applications of emerging immunotherapeutic strategies for Epstein-Barr virus-associated malignancies

Khanna, Rajiv, Moss, Denis and Gandhi, Maher (2005). Technology Insight: Applications of emerging immunotherapeutic strategies for Epstein-Barr virus-associated malignancies. Nature Clinical Practice Oncology, 2 (3), 138-149. doi: 10.1038/ncponc0107

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

Gandhi, Maher K. and Khanna, Rajiv (2004). Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infectious Diseases, 4 (12), 725-738. doi: 10.1016/S1473-3099(04)01202-2

Epstein-Barr virus-associated Hodgkin's lymphoma

Gandhi, Maher K., Tellam, Judy T. and Khanna, Rajiv (2004). Epstein-Barr virus-associated Hodgkin's lymphoma. British Journal of Haematology, 125 (3), 267-281. doi: 10.1111/j.1365-2141.2004.04902.x

Human cytomegalovirus-specific immunity following haemopoietic stem cell transplantation

Gandhi, MK, Wills, MR, Sissons, JGP and Carmichael, AJ (2003). Human cytomegalovirus-specific immunity following haemopoietic stem cell transplantation. Blood Reviews, 17 (4), 259-264. doi: 10.1016/S0268-960X(03)00028-6

Late diversification in the clonal composition of human cytomegalovirus-specific CD8(+) T cells following allogeneic hemopoietic stem cell transplantation

Gandhi, MK, Wills, MR, Okecha, G, Day, EK, Hicks, R, Marcus, RE, Sissons, JGP and Carmichael, AJ (2003). Late diversification in the clonal composition of human cytomegalovirus-specific CD8(+) T cells following allogeneic hemopoietic stem cell transplantation. Blood, 102 (9), 3427-3438. doi: 10.1182/blood-200-12-3689

Significant and persistent loss of bone mineral density in the femoral neck after haematopoietic stem cell transplantation: long-term follow-up of a prospective study

Gandhi, MK, Lekamwasam, S, Inman, I, Kaptoge, S, Sizer, L, Love, S, Bearcroft, PW, Milligan, TP, Price, CP, Marcus, RE and Compston, JE (2003). Significant and persistent loss of bone mineral density in the femoral neck after haematopoietic stem cell transplantation: long-term follow-up of a prospective study. British Journal of Haematology, 121 (3), 462-468. doi: 10.1046/j.1365-2141.2003.04303.x

Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8(+) T cell response

Wills, MR, Okecha, G, Weekes, MP, Gandhi, MK, Sissons, PJG and Carmichael, AJ (2002). Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8(+) T cell response. Journal of Immunology, 168 (11), 5455-5464. doi: 10.4049/jimmunol.168.11.5455

Antibody responses to vaccinations given within the first two years after transplant are similar between autologous peripheral blood stem cell and bone marrow transplant recipients

Gandhi, MK, Egner, W, Sizer, L, Inman, I, Zambon, M, Craig, JIO and Marcus, RE (2001). Antibody responses to vaccinations given within the first two years after transplant are similar between autologous peripheral blood stem cell and bone marrow transplant recipients. Bone Marrow Transplantation, 28 (8), 775-781. doi: 10.1038/sj.bmt.1703239

A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations

Coulthard, SA, Rabello, C, Robson, J, Howell, C, Minto, L, Middleton, PG, Gandhi, MK, Jackson, G, McLelland, J, O'Brien, H, Smith, S, Reid, MM, Pearson, ADJ and Hall, AG (2000). A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations. British Journal of Haematology, 110 (3), 599-604. doi: 10.1046/j.1365-2141.2000.02218.x

Status of Cytomegalovirus prevention and treatment in 2000

Zaia, John A., Sissons, J. G. Patrick, Riddell, Stanley, Diamond, Don J., Wills, M. R., Carmichael, A. J., Weekes, M. P., Gandhi, M., La Rosa, C., Villacres, M., Lacey, S., Markel, S. and Sun, J. (2000). Status of Cytomegalovirus prevention and treatment in 2000. Hematology, 339-355. doi: 10.1182/asheducation-2000.1.339

A comparison of CD34(+) cell selected and unselected autologous peripheral blood stem cell transplantation for multiple myeloma: a case controlled analysis

Gandhi, MK, Jestice, HK, Scott, MA, Bloxham, DM, Bass, G, Craig, JIO and Marcus, RE (1999). A comparison of CD34(+) cell selected and unselected autologous peripheral blood stem cell transplantation for multiple myeloma: a case controlled analysis. Bone Marrow Transplantation, 24 (4), 369-375. doi: 10.1038/sj.bmt.1701938

The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients

Gandhi, MK, Jestice, K, Scott, MA, Bloxham, D, Bass, G and Marcus, RE (1999). The minimum CD34 threshold depends on prior chemotherapy in autologous peripheral blood stem cell recipients. Bone Marrow Transplantation, 23 (1), 9-13. doi: 10.1038/sj.bmt.1701530

A trend towards an increased incidence of chronic graft-versus-host disease following allogeneic peripheral blood progenitor cell transplantation: a case controlled study

Scott, MA, Gandhi, MK, Jestice, HK, Mahendra, P, Bass, G and Marcus, RE (1998). A trend towards an increased incidence of chronic graft-versus-host disease following allogeneic peripheral blood progenitor cell transplantation: a case controlled study. Bone Marrow Transplantation, 22 (3), 273-276. doi: 10.1038/sj.bmt.1701327

The Alder-Reilly anomaly in association with the myelodysplastic syndrome

Gandhi, MK, Howard, MR and Hamilton, PJ (1996). The Alder-Reilly anomaly in association with the myelodysplastic syndrome. Clinical and Laboratory Haematology, 18 (1), 39-40.

An Unusual Case of Hypersomnolence Syndrome

Gandhi, MK and Chandler, JE (1995). An Unusual Case of Hypersomnolence Syndrome. Clinical and Laboratory Haematology, 17 (3), 247-250. doi: 10.1111/j.1365-2257.1995.tb01245.x

A Case of Transfusion-Acquired Hepatitis-C

Wreghitt, TG, Gandhi, MK, Gray, JJ, Blagdon, J, Rankin, A and Coates, PB (1993). A Case of Transfusion-Acquired Hepatitis-C. Clinical and Laboratory Haematology, 15 (2), 141-144. doi: 10.1111/j.1365-2257.1993.tb00138.x

Inducing Remission in Drug-Resistant Acute Myeloid-Leukemia with Cyclosporine-a

Gandhi, MK, Keidan, AJ, Rees, Jkh, Twentyman, P and Coates, PB (1993). Inducing Remission in Drug-Resistant Acute Myeloid-Leukemia with Cyclosporine-a. Clinical and Laboratory Haematology, 15 (3), 219-221. doi: 10.1111/j.1365-2257.1993.tb01085.x

ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS

Rijal, Sewa, Lim, Jun Hee, Smyth, Lillian, Coombes, Caitlin, Jain, Sanjiv, Saxena, Kartik, Trotman, Judith, Verner, Emma, Gandhi, Maher K., Gandhi, Kaushal and Talaulikar, Dipti (2023). ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS. HOBOKEN: WILEY.

Identification of Genetic Subtypes in Follicular Lymphoma

Shelton, Victoria, Isaev, Keren, Liu, Ting, Silva, Anjali, Detroja, Rajesh, Bakhtiari, Mehran, Calvente, Lourdes, Hong, Michael, Modi, Saloni, Hershenfeld, Samantha A., Ludvigsen, Maja, d'Amore, Francesco Annibale, Brodtkorb, Marianne, Johnson, Nathalie A., Baetz, Tara, LeBrun, David, Tobin, Josh, Gandhi, Maher K., Mungall, Andrew J., Steidl, Christian, Delabie, Jan, Tremblay-Lemay, Rosemarie, Kahl, Brad S., Evens, Andrew M and Kridel, Robert (2022). Identification of Genetic Subtypes in Follicular Lymphoma. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-164610

Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma

Gunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Bednarska, Karolina, Brosda, Sandra, Zaharia, Andreea, Tsang, Hennes, de Long, Lilia M., Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Gould, Clare, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher K. (2022). Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma. Third AACR International Meeting: Advances in Malignant Lymphoma: Maximizing the Basic-Translational Interface for Clinical Application, 23-25 June 2022, Boston, MA USA. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/2643-3249.lymphoma22-a17

Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma

Tsang, Hennes, Patch, Ann-Marie, Keane, Colm, Law, Soi C., Gunawardana, Jay, Blombery, Piers, Thompson, Ella R., Sabdia, Muhammed B., De Long, Lilia Merida, Belle, Clemence J., Nath, Karthik, Tobin, Joshua W.D., Kazakoff, Stephen H., Seymour, John F., MacManus, Michael and Gandhi, Maher K. (2020). Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2020-135954

Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade

Nath, Karthik, Law, Soi C., Sabdia, Muhammed B., De Long, Lilia Merida, Shanavas, Mohamed, Tobin, Joshua W. D., Gunawardana, Jay, Vari, Frank, Halliday, Sarah-Jane, Hernandez, Annette, Cross, Donna, Bird, Robert J., Keane, Colm and Gandhi, Maher K. (2019). Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7 - 10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-130050

EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy

Gandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E. and Keane, C. (2019). EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy. 15th International Conference on Malignant Lymphoma, Lugano, Switzerland, 18–22 June 2019. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.91_2629

B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL

Gould, Clare, Keane, Colm, Murigneux, Valentine, Oey, Harald, Ellis, Jonathan, Birch, Simone, Gunawardana, Jay, Talaulikar, Dipti, Hertzberg, Mark S., Jones, Kimberley and Gandhi, Maher K. (2019). B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL. ASH Annual Meeting, Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-126537

A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial

Abro, Emad Uddin, Law, Soi C., Keane, Colm, Birch, Simone, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Johnson, Peter, Trotman, Judith, Berkahn, Leanne, Fulham, Michael, Anderson, Richard A., Saunderson, Anne L., Gunawardana, Jay, Cross, Donna, Hernandez, Annette, Halliday, Sarah-Jane, Bird, Robert, Law, W. P., Gill, Devinder and Gandhi, Maher K. (2018). A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial. 60th ASH Annual Meeting, San Diego, CA United States, 1-4 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-112008

Elevated LAG-3 111,xpression in the Tumor Microenvironement of Patients with DLBCL Is Associated with a Non-GCB Phenotype and Poor Prognosis

Keane, Colm, Law, Soi C., Gould, Clare, Francis, Santiyagu, Abro, Emad Uddin, Tobin, Joshua W. D., Birch, Simone, Gifford, Grace, Gabreilli, Sara, Stevenson, William S., Talaulikar, Dipti, Gill, Anthony, Jain, Sanjiv, Cross, Donna, Hernadez, Annette, Halliday, Sarah-Jane, Bird, Robert, Hertzberg, Mark and Gandhi, Maher K. (2018). Elevated LAG-3 111,xpression in the Tumor Microenvironement of Patients with DLBCL Is Associated with a Non-GCB Phenotype and Poor Prognosis. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 1-4 December 2018. Washington, DC, Untied States: American Society of Hematology. doi: 10.1182/blood-2018-99-112830

Outcomes of Stages I and II Follicular Lymphoma in the Era of 18F-FDG PET-CT Staging: An International Collaborative Study from the Australian Lymphoma Alliance

Tobin, Joshua W. D., Rule, Gabrielle, Colvin, Katherine, Calvente, Lourdes, Hodgson, David C., Dunduru, Chengetai, Bell, Stephen, Gallo, James, Tsang, Erica, Tan, Xuan, Pearce, Jessica, Wong, Jonathan, Campbell, Robert, Tneh, Shao Yang, Shorten, Sophie, Ng, Melissa Liet Hing, Darch, Jacob, Cochrane, Tara, Tam, Constantine S., Abro, Emad Uddin, Hawkes, Eliza, Hodges, Georgina, Talaulikar, Dipti, Gilbertson, Michael P., Johnson, Anna, Kansara, Roopesh R., Villa, Diego, Savage, Kerry J., Morris, Kirk Lachlan ... Hapgood, Greg (2018). Outcomes of Stages I and II Follicular Lymphoma in the Era of 18F-FDG PET-CT Staging: An International Collaborative Study from the Australian Lymphoma Alliance. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-114097

The Tumor Microenvironment of Nodular Lymphocyte Predominant Hodgkin Lymphoma Is a Unique Immunobiological Entity Distinct from Classical Hodgkin Lymphoma

Gunawardana, Jay, Bednarska, Karolina, Law, Soi C., Lee, Justina, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Birch, Simone, Keane, Colm and Gandhi, Maher K. (2018). The Tumor Microenvironment of Nodular Lymphocyte Predominant Hodgkin Lymphoma Is a Unique Immunobiological Entity Distinct from Classical Hodgkin Lymphoma. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego CA, United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-115836

The Tumour Microenvironment as an Independent Prognostic Biomarker in Follicular Lymphoma

Tobin, J., Keane, C., Mollee, P., Birch, S., Gould, C., Gunawardana, J., Hoang, T., Savarimuthu, S., Ma, T., Li, L., Murigneux, V. , Fink, L., Matigian, N. and Gandhi, M. K. (2018). The Tumour Microenvironment as an Independent Prognostic Biomarker in Follicular Lymphoma. RACP Congress 2018, Disruption for Healthy Futures, Sydney, NSW Australia, 14–16 May 2018. Hoboken, NJ United States: Wiley. doi: 10.1111/imj.2_13826

The tumor microenvironment is independently prognostic of conventional and clinicogenetic risk models in follicular lymphoma

Tobin, Joshua W. D., Keane, Colm, Mollee, Peter, Birch, Simone, Gould, Clare, Gunawardana, Jay, Hoang, Thanh , Ma, Ti, Abro, Emad Uddin, Shanavas, Mohamed, Yoo, Hyung, Li, Li, Scuffham, Paul, Murigneux, Valentine, Fink, Lynn, Matigian, Nicholas, Vari, Frank, Francis, Santiyagu and Gandhi, Maher K. (2017). The tumor microenvironment is independently prognostic of conventional and clinicogenetic risk models in follicular lymphoma. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA United States, 9-12 December 2017. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V130.Suppl_1.728.728

Prognostic role of antitumor immunity within tumor microenvironment in follicular lymphoma

Yoo, H., Tobin, J., Palmatier, L., Gandhi, M. and Li, L. (2017). Prognostic role of antitumor immunity within tumor microenvironment in follicular lymphoma. Southern Regional Meeting of the American Federation for Medical Research (AFMR), New Orleans, LA, United States, 11-13 February 2017. London, United Kingdom: BMJ Group. doi: 10.1136/jim-2016-000393.429

The T-Cell Receptor Repertoire Predicts Interim-PET in Patients with DLBCL Treated with R-CHOP: An Observational Study from a Prospective Clinical Trial

Shanavas, Mohamed, Hertzberg, Mark, Hicks, Rodney J., Seymour, John F., Tobin, Joshua W. D., Mathews, Marina, Francis, Santiyagu, Vari, Frank, Gandhi, Maher K. and Keane, Colm (2017). The T-Cell Receptor Repertoire Predicts Interim-PET in Patients with DLBCL Treated with R-CHOP: An Observational Study from a Prospective Clinical Trial. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA United States, 9-12 December 2017. Washington, DC United States: American Society of Hematology.

The impact of EBV upon the tumor microenvironment and mutational profile of primary CNS lymphoma in PTLD

Gandhi, Maher K., Keane, Colm, Tobin, Joshua W. D., Talaulikar, Dipti, Jain, Sanjiv, Vari, Frank, Kruze, Lutz, Murigneux, Valentine, Fink, Lynn, Gunawardana, Jithendra, Gould, Clare, Oey, Harold, Fink, Susanne, Trappe, Ralf Ulrich, Mathews, Marina, Francis, Santiyagu and Hoang, Thanh (2017). The impact of EBV upon the tumor microenvironment and mutational profile of primary CNS lymphoma in PTLD. 59th Annual Meeting of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 9-12 December 2017. Washington, DC, United States: American Society of Hematology.

A Novel Anti-Lymphoma Immune Evasion Mediated By the Interaction Between PD-1 Enriched NK-Cells and CD163+PD-L1+PD-L2+Tumor Associated Macrophages, That Is More Prominent in Hodgkin Lymphoma Than Diffuse Large B-Cell Lymphoma

Gandhi, Maher K., Arpon, David, Keane, Colm, Han, Erica, Tobin, Josh, Bird, Robert, Hertzberg, Mark S., Self, Marlene, Cross, Donna, Hernandez, Annette and Vari, Frank (2016). A Novel Anti-Lymphoma Immune Evasion Mediated By the Interaction Between PD-1 Enriched NK-Cells and CD163+PD-L1+PD-L2+Tumor Associated Macrophages, That Is More Prominent in Hodgkin Lymphoma Than Diffuse Large B-Cell Lymphoma. 58th Annual Meeting and Exposition of the American-Society-of-Hematology, San Diego CA, United States, 3-6 December 2016. Washington, DC United States: American Society of Hematology.

Low-dose doxorubicin reduces an immunosuppressive Ly6C(lo) monocyte population to improve efficacy of anti-41BB monoclonal antibody against B cell lymphoma

Mckee, S. J., Doff, B. L., Gandhi, M. K. and Mattarollo, S. R. (2016). Low-dose doxorubicin reduces an immunosuppressive Ly6C(lo) monocyte population to improve efficacy of anti-41BB monoclonal antibody against B cell lymphoma. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200

The IRE1/XBP1) pathway is a critical regulatory hub for human NK-cell mediated lysis and motility that modulates the actin-binding protein XIRP1

Gandhi, M. K., Mujaj, S., Vari, F., Cui, Q., Nourse, J. P., Han, E. and Cristino, A. (2016). The IRE1/XBP1) pathway is a critical regulatory hub for human NK-cell mediated lysis and motility that modulates the actin-binding protein XIRP1. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Early Treatment Intensification with R-ICE Chemotherapy Followed By Autologous Stem Cell Transplantation (ASCT) Using Zevalin-BEAM for Patients with Poor Risk Diffuse Large B-Cell Lymphoma (DLBCL) As Identified By Interim PET/CT Scan Performed after Four

Hertzberg, Mark S., Gandhi, Maher K., Butcher, Belinda, Columbus, Ruth, Taper, John, Trotman, Judith, Gill, Devinder, Ho, Shir-Jing, Fay, Kelth, Cull, Gavin, Grigg, Andrew P., Chong, Geoff, Lewis, Ian D., Milliken, Sam, Renwick, William, Hahn, Uwe, Filshie, Robin, Watson, Anne-Marie, Kannourakis, George, Wolf, Max, Wirth, Andrew, Warburton, Pauline Therese, Larsen, Stephen Robert, Seymour, John F. and Hicks, Rodney (2015). Early Treatment Intensification with R-ICE Chemotherapy Followed By Autologous Stem Cell Transplantation (ASCT) Using Zevalin-BEAM for Patients with Poor Risk Diffuse Large B-Cell Lymphoma (DLBCL) As Identified By Interim PET/CT Scan Performed after Four. 57th Annual Meeting of the American Society of Hematology, Orlando, United States, Dec 05-08, 2015. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood.V126.23.815.815

Improving conventional prognosticators in diffuse large B cell lymphoma using marker ratios

Lecao K.-A., Keane C., Han E., Talaulikar D. and Gandhi M. (2015). Improving conventional prognosticators in diffuse large B cell lymphoma using marker ratios. Scientific Stream at Big Data in Health Analytics 2015, BigData 2015, Sydney; Australia, October 20, 2015-October 21, 2015. Aachen, Germany: Rheinisch-Westfaelische Technische Hochschule Aachen.

Pre-treatment circulating tumor DNA as a biomarker for disease burden in diffuse large B cell lymphoma (DLBCL)

Scherer, Florian, Kurtz, David Matthew, Green, Michael Richard, Newman, Aaron M., Klass, Daniel M., Zhou, Li, Krishnan, Rashi, Liu, Chih Long, Glover, Cynthia, Ohgami, Robert S., Hicks, Rodney J., Keane, Colm, Kong, Katherine A., Faham, Malek, Hertzberg, Mark S., Gandhi, Maher K., Advani, Ranjana H., Levy, Ronald, Diehn, Maximilian and Alizadeh, Ash A. (2015). Pre-treatment circulating tumor DNA as a biomarker for disease burden in diffuse large B cell lymphoma (DLBCL). Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, United States, May 29-June 2, 2015. Alexandria, United States: American Society of Clinical Oncology.

The T Cell Receptor (TCR) Repertoire Is a Key Determinant of the Tumour Microenvironment (TME) in Diffuse Large B Cell Lymphoma (DLBCL)

Keane, Colm, Jones, Kimberly, Gould, Clare, Hamm, David, Wood, Peter, Birch, Simone, Crooks, Pauline, Green, Michael R., Taulaulikar, Dipti, Jain, Sanjiv, Tobin, Josh and Gandhi, Maher K. (2015). The T Cell Receptor (TCR) Repertoire Is a Key Determinant of the Tumour Microenvironment (TME) in Diffuse Large B Cell Lymphoma (DLBCL). 55th Annual Meeting and Exposition of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. WASHINGTON: AMER SOC HEMATOLOGY.

Noninvasive monitoring of cellular versus acellular tumor DNA from immunoglobulin genes for DLBCL

Kurtz, David Matthew, Green, Michael R., Bratman, Scott Victor, Liu, Chih-Long, Glover, Cynthia, Keane, Colm, Kong, Katie, Faham, Malek, Miklos, David Bernard, Advani, Ranjana H., Levy, Ronald, Hertzberg, Mark S., Gandhi, Maher K., Diehn, Maximilian and Alizadeh, Ash A. (2014). Noninvasive monitoring of cellular versus acellular tumor DNA from immunoglobulin genes for DLBCL. 50th Annual Meeting of the American Society of Clinical Oncology, Chicago IL United States, May 30-June 3, 2014. Alexandria VA, United States: American Society of Clinical Oncology.

Validation of Elevated Blood Soluble PD-L1 As an Independent Prognostic Marker in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Fest, Thierry, Cerhan, James R., Gandhi, Maher K., Azzaoui, Imane, Crooks, Pauline, Maurer, Matthew J., Milpied, Noel, Hertzberg, Mark S., Lamy, Thierry, Ansell, Stephen M., Slager, Susan L., Feldman, Andrew L., Roussel, Mikael, Habermann, Thomas M., Ghesquieres, Herve, Witzig, Thomas E., Link, Brian K. and Rossille, Delphine (2014). Validation of Elevated Blood Soluble PD-L1 As an Independent Prognostic Marker in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL). 56th Annual Meeting of the American Society of Hematology, San Francisco, CA United States, 06-09 December 2014. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V124.21.2998.2998

HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies

Gandhi, Maher K., Brennan, Rebekah M., Wockner, Leesa, Chattopadhyay, Pratip K., Roederer, Mario, Price, David A., Cole, David K., Hassan, Brekhna, Beck, Konrad, Thornton, Alycia, Gottlieb, David, Ritchie, David, Seymour, John F., Kumarasinghe, Gayathri, Burrows, Scott R. and Jones, Kimberley (2013). HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY.

FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.

Camilleri, Emily, Aya-Bonilla, Carlos, Nourse, Jamie, Brown, Philip J., Banham, Alison H., Marlton, Paula, Gandhi, Maher K. and Griffiths, Lyn R. (2013). FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.TUMIMM2012-B38

Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients

Taylor, Emma, Jones, Mark, Hourigan, Matthew J., Johnson, David W., Gill, Devinder S., Isbel, Nicole, Hawley, Carmel M., Marlton, Paula, Gandhi, Maher K., Campbell, Scott B. and Mollee, Peter (2013). Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients. 55th Annual Meeting of the American Society of Hematology, New Orleans, LA United States, 7-10 December 2013. Washington, DC United States: American Society of Hematology.

Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms

Talaulikar, Dipti, Cendales, Yvonne Gonzalez, Shadbolt, Bruce, Gandhi, Maher and Warren, Hilary (2012). Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms. MALDEN: WILEY-BLACKWELL.

Modulation of the unfolded protein response via XBP1 splicing: a novel mechanism that regulates Natural Killer cell effector function.

Mujaj, Sally, Gandhi, Maher, Vari, Frank and Nourse, Jamie (2012). Modulation of the unfolded protein response via XBP1 splicing: a novel mechanism that regulates Natural Killer cell effector function.. 99th Annual Meeting of the American-Association-of-Immunologists, Boston Ma, May 04-08, 2012. BETHESDA: AMER ASSOC IMMUNOLOGISTS.

Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma

Camilleri, Emily T., Aya-Bonilla, Carlos A., Brown, Philip J., Banham, Alison, Marlton, Paula, Gandhi, Maher K. and Griffiths, Lyn R. (2012). Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma. 54th Annual Meeting and Exposition of the American Society of Hematology (ASH), Atlanta, GA, United States, 8-11 December 2012. Washington, DC, United States: American Society of Hematology.

Serum CD163 and TARC in Combination As Disease Response Biomarkers in Classical Hodgkin Lymphoma

Gandhi, Maher K., Vari, Frank, Crooks, Pauline, Keane, Colm, Nourse, Jamie P., Seymour, Louise A., Ritchie, David, Gottlieb, David, Gill, Devinder and Jones, Kimberley (2012). Serum CD163 and TARC in Combination As Disease Response Biomarkers in Classical Hodgkin Lymphoma. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta GA, United States, 8-11 December 2012. Washington, DC United States: American Society of Hematology.

A Multi-Centre, Single-Arm, Open-Label Study Evaluating the Safety and Efficacy of Fixed Dose Rituximab in Patients with Refractory, Relapsing or Chronic Idiopathic Thrombocytopenic Purpura (R-ITP1000 Study) and Exploring Rituximab Response with the FcGammaR3A Polymorphisms

Huyen Tran, , Nourse, Jamie P., Lea, Rod, Brighton, Timothy A., Grigg, Andrew, McRae, Simon, Thurley, Daniel, Gandhi, Maher and Catalano, John (2011). A Multi-Centre, Single-Arm, Open-Label Study Evaluating the Safety and Efficacy of Fixed Dose Rituximab in Patients with Refractory, Relapsing or Chronic Idiopathic Thrombocytopenic Purpura (R-ITP1000 Study) and Exploring Rituximab Response with the FcGammaR3A Polymorphisms. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego Ca, Dec 10-13, 2011. WASHINGTON: AMER SOC HEMATOLOGY.

Monocytes Are Associated with Impaired T-Cell Immunity and Residual Interim-PET/CT Avidity After 4 Cycles of CHOP-R In Patients with High-Risk DLBCL

Gandhi, MK, Hertzberg, MS, Han, E, Seymour, JF, Hicks, R, Gill, DS, Keane, C, Crooks, P, Radford, K and Vari, F (2011). Monocytes Are Associated with Impaired T-Cell Immunity and Residual Interim-PET/CT Avidity After 4 Cycles of CHOP-R In Patients with High-Risk DLBCL. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 10-13, 2011. WASHINGTON: AMER SOC HEMATOLOGY.

Tissue Microarray in DLBCL Patients receiving R-CHOP Chemo-Immunotherapy Shows Survival Benefit for Coexpression of LMO2/BCL6

Keane, C, Shen, L, Han, E, Nourse, JP, Lea, R, Mollee, P, Gill, DS and Gandhi, MK (2011). Tissue Microarray in DLBCL Patients receiving R-CHOP Chemo-Immunotherapy Shows Survival Benefit for Coexpression of LMO2/BCL6. 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 10-13, 2011. WASHINGTON: AMER SOC HEMATOLOGY.

Tissue microarray in DLBCL patients receiving CHOP-R chemo-immunotherapy shows survival benefit for coexpression of LMO2/BCL6 and poor outcome for EBER-ISH positive patients

Keane, C., Shen, L., Nourse, J., Han, E., Jones, K. and Gandhi, M. (2011). Tissue microarray in DLBCL patients receiving CHOP-R chemo-immunotherapy shows survival benefit for coexpression of LMO2/BCL6 and poor outcome for EBER-ISH positive patients. 11th International Conference on Malignant Lymphoma, Lugano, Switzerland, 15-18 June 2011. Oxford, United Kingdom: Oxford University Press.

Ebv-Positive Dlbcl of the Elderly Is a Distinct Clinico-Biological Entity with Poor Outcome in Chop-R Treated Patients

Gandhi, M., Keane, C., Nourse, J., Jones, K., Ross, N., Han, E. and Nguyen-Van, D. (2010). Ebv-Positive Dlbcl of the Elderly Is a Distinct Clinico-Biological Entity with Poor Outcome in Chop-R Treated Patients. 15th Annual Meeting of the European-Hematology-Association, Barcelona Spain, June 10-13, 2010. Pavia, Italy: Fondazione Ferrata Storti.

EBV MicroRNA Expression in Virus Driven B-Cell Differentiation and Lymphomagenesis

Nourse, Jamie P., Crooks, Pauline, Van, Do Nguyen, Jones, Kimberley, Ross, Nathan and Gandhi, Maher K. (2009). EBV MicroRNA Expression in Virus Driven B-Cell Differentiation and Lymphomagenesis. 51st Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 05-08, 2009. WASHINGTON: AMER SOC HEMATOLOGY.

Cell-free Epstein-Barr Virus DNA is a Specific Biomarker for Tumor Burden in EBV-associated Lymphomas

Jones, Kimberley, Nourse, J., Crooks, P., Gottlieb, D. and Gandhi, Mahei (2009). Cell-free Epstein-Barr Virus DNA is a Specific Biomarker for Tumor Burden in EBV-associated Lymphomas. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Epstein-Barr Virus-specific T Cells as Therapy for Relapsed/Refractory EBV-positive Lymphomas

Jones, Kimberley, Vari, Frank, Khanna, Rajiv, Han, Erica, Singh, Sanjleena, Ritchie, David and Gandhi, Maher K. (2009). Epstein-Barr Virus-specific T Cells as Therapy for Relapsed/Refractory EBV-positive Lymphomas. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Mechanisms Underlying the Selective Impairment of Epstein Barr Virus-Nuclear Antigen I-specific Effector T Cells Observed in PTLD

Jones, Kimberley, Nouise, J., Morrison, L., Vari, Frank, Moss, D. and Gandhi, Mahei K. (2009). Mechanisms Underlying the Selective Impairment of Epstein Barr Virus-Nuclear Antigen I-specific Effector T Cells Observed in PTLD. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Ebv Microrna Expression in An In-Vitro Model of B-Cell Differentiation and Lymphomagenesis

Nourse, P., Jones, K., Crooks, P. and Gandhi, M. K. (2009). Ebv Microrna Expression in An In-Vitro Model of B-Cell Differentiation and Lymphomagenesis. 14th Annual Meeting of the European-Hematology-Association, Berlin Germany, Jun 04-07, 2009. WASHINGTON: AMER SOC HEMATOLOGY.

Immunosuppression (IST) Can Be Safely Ceased during Chemotherapy for PTLD in Renal Transplant Patients

Hourigan, Matthew J., Johnson, David W., Jones, Mark, Gill, Devinder S., Isbel, Nikki, Hawley, Carmel M., Marlton, Paula, Ghandhi, Maher, Campbell, Scott B. and Mollee, Peter (2007). Immunosuppression (IST) Can Be Safely Ceased during Chemotherapy for PTLD in Renal Transplant Patients. American Transplant Congress 2007, USA, 5-9 May 2007. UK: Wiley-Blackwell Publising Ltd.. doi: 10.1111/j.1600-6143.2007.01811.x

Immunosuppression (IST) can be safely ceased during chemotherapy for PTLD in renal transplant patients

Hourigan, Matthew J., Johnson, David W., Jones, Mark, Gill, Devinder S., Isbel, Nikki, Hawley, Carmel M., Marlton, Paula, Gandhi, Maher, Campbell, Scott B. and Mollee, Peter (2007). Immunosuppression (IST) can be safely ceased during chemotherapy for PTLD in renal transplant patients. American Transplant Congress, San Francisco, CA, USA, 5-9 May 2007. Oxford, England: Wiley-Blackwell. doi: 10.1111/j.1600-6143.2007.01811.x

Immunosuppression (IST) can be safely ceased during chemotherapy for PTLD in renal transplant patients

Mollee, P, Hourigan, M, Johnson, D, Jones, M, Isabel, N, Hawley, C, Marlton, P, Gandhi, M, Campbell, S and Gill, D (2007). Immunosuppression (IST) can be safely ceased during chemotherapy for PTLD in renal transplant patients. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta Ga, Dec 08-11, 2007. WASHINGTON: BLACKWELL PUBLISHING.

LAG-3 expressing lymphocytes suppress EBV latent membrane protein-specific T cell function in Hodgkins lymphoma patients

Gandhi, M, Lambley, E, Marlton, P, Gill, D, Seymour, J, Wolf, M, Prince, M, Elliott, S and Khanna, R (2005). LAG-3 expressing lymphocytes suppress EBV latent membrane protein-specific T cell function in Hodgkins lymphoma patients. 9th International Conference on Malignant Lymphoma, Lugano Switzerland, Jun 09-11, 2005. OXFORD: OXFORD UNIV PRESS.

Identification of novel proteins associated with the Mpl cytoplasmic domain.

Gandhi, M and Drachman, JG (2001). Identification of novel proteins associated with the Mpl cytoplasmic domain.. WASHINGTON: AMER SOC HEMATOLOGY.

Significant and persistant loss of bone mineral density (BMD) in the femoral neck after haematopoietic stem cell transplantation: A prospective study.

Gandhi, MK, Lekamwasam, S, Inman, , Kaptoge, S, Sizer, L, Love, S, Craig, JIO, Marcus, RE and Compston, J (2001). Significant and persistant loss of bone mineral density (BMD) in the femoral neck after haematopoietic stem cell transplantation: A prospective study.. WASHINGTON: AMER SOC HEMATOLOGY.

Changes in the clonal composition of CMV-specific CD8+ cytotoxic T-lymphocytes (CTL) between allogeneic stem cell transplant recipients and their donors.

Gandhi, MK, Willis, MR, Craig, JIO, Marcus, RE, Sissons, JP and Carmichael, AJ (2001). Changes in the clonal composition of CMV-specific CD8+ cytotoxic T-lymphocytes (CTL) between allogeneic stem cell transplant recipients and their donors.. WASHINGTON: AMER SOC HEMATOLOGY.

The clonal reconstitution of human cytomegalovirus-specific memory cytotoxic T-lymphocytes following allogeneic stem cell transplantation.

Gandhi, MK, Carmichael, AJ, Wills, MR, Craig, JIO, Marcus, RE and Sissons, JP (2000). The clonal reconstitution of human cytomegalovirus-specific memory cytotoxic T-lymphocytes following allogeneic stem cell transplantation.. WASHINGTON: AMER SOC HEMATOLOGY.

Influenza vaccination is ineffective in the first 2 years after stem cell transplant.

Gandhi, MK, Egner, W, Inman, I, Craig, JIO and Marcus, RE (1999). Influenza vaccination is ineffective in the first 2 years after stem cell transplant.. OXFORD: BLACKWELL SCIENCE LTD.

A case controlled comparison between CD34(+) cell selected and unselected autologous PBSCT for multiple myeloma.

Gandhi, MK, Jestice, HK, Scott, MA, Bloxham, DM, Bass, G, Craig, J and Marcus, RE (1999). A case controlled comparison between CD34(+) cell selected and unselected autologous PBSCT for multiple myeloma.. BASINGSTOKE: STOCKTON PRESS.

Reduced bone mineral density (BMD) in males and females after bone marrow transplant (BMT).

Gandhi, MK, Sizer, L, Compston, JE, Prevost, A and Marcus, RE (1998). Reduced bone mineral density (BMD) in males and females after bone marrow transplant (BMT).. OXFORD: AMER SOC HEMATOLOGY.

Allogeneic peripheral blood progenitor cell transplantation: A case controlled study of GVHD.

Scott, MA, Gandhi, MK, Jestice, HK, Mahendra, P and Marcus, RE (1998). Allogeneic peripheral blood progenitor cell transplantation: A case controlled study of GVHD.. BASINGSTOKE: STOCKTON PRESS.

Febrile neutropenia after hematopoietic stem cell mobilization with chemotherapy and G-CSF does not affect collection of adequate numbers of CD34+ cells.

Yee, K, Tu, JV, MacKinnon, J, Gandhi, M, Stewart, AK, Saragosa, R, Keating, A and Crump, M (1997). Febrile neutropenia after hematopoietic stem cell mobilization with chemotherapy and G-CSF does not affect collection of adequate numbers of CD34+ cells.. PHILADELPHIA: W B SAUNDERS CO.

Autologous marrow and/or blood cell transplantation (ABMT) for follicular large cell lymphoma (FLC)

Simpson, DR, Gandhi, MK, Stewart, AK, Crump, M and Keating, A (1997). Autologous marrow and/or blood cell transplantation (ABMT) for follicular large cell lymphoma (FLC). CHARLOTTESVILLE: CARDEN JENNINGS PUBL CO LTD.

Febrile neutropenia does not affect collection of adequate CD34+ cells after mobilization with chemotherapy and G-CSF

Yee, K, Tu, JV, MacKinnon, J, Gandhi, M, Stewart, AK, Saragosa, R, Keating, A and Crump, M (1997). Febrile neutropenia does not affect collection of adequate CD34+ cells after mobilization with chemotherapy and G-CSF. CHARLOTTESVILLE: CARDEN JENNINGS PUBL CO LTD.

Pre-autologous bone marrow transplant (ABMT) screening for HLA antibodies does not predict for platelet alloimmunization post-ABMT: A case controlled study

Gandhi, MK, Simpson, D, Yee, K, MacKinnon, J, Stewart, AK, Crump, M and Keating, A (1997). Pre-autologous bone marrow transplant (ABMT) screening for HLA antibodies does not predict for platelet alloimmunization post-ABMT: A case controlled study. CHARLOTTESVILLE: CARDEN JENNINGS PUBL CO LTD.

Qualitative difference in CD34 counts in multiple myeloma (MM) and breast cancer (BCa) patient (PT) stem cell grafts.

Simpson, DR, Gandhi, MK, Stewart, AK, Crump, M and Keating, A (1997). Qualitative difference in CD34 counts in multiple myeloma (MM) and breast cancer (BCa) patient (PT) stem cell grafts.. CHARLOTTESVILLE: CARDEN JENNINGS PUBL CO LTD.

A multicentre study of granulocyte-macrophage colony stimulating factor (GM-CSF) in combination with consolidation therapy in adult acute myeloid leukemia (AML).

Keating, A, Gandhi, MK, Crump, M, Smith, A, Belch, A and Baker, MA (1996). A multicentre study of granulocyte-macrophage colony stimulating factor (GM-CSF) in combination with consolidation therapy in adult acute myeloid leukemia (AML).. PHILADELPHIA: W B SAUNDERS CO.

Treatment of acute myeloid leukemia (AML) at diagnosis in 99 unselected adults with high dose ARA-C (HIDAC) and mitoxantrone: Long-term follow-up.

Keating, A, Gandhi, MK, Crump, M, Smith, A, Belch, A and Baker, MA (1996). Treatment of acute myeloid leukemia (AML) at diagnosis in 99 unselected adults with high dose ARA-C (HIDAC) and mitoxantrone: Long-term follow-up.. PHILADELPHIA: W B SAUNDERS CO.

Congenital deficiency of thiopurine methyltransferase as a cause of pancytopenia in patients treated with azathioprine

Hall, AG, Rabello, C, Jackson, G, Gandhi, MK and OBrien, H (1996). Congenital deficiency of thiopurine methyltransferase as a cause of pancytopenia in patients treated with azathioprine. OXFORD: BLACKWELL SCIENCE LTD.