Professor Geoffrey Hill

Honorary Professor

Royal Brisbane Clinical Unit
Faculty of Medicine

Honorary Professor

The University of Queensland Diamantina Institute
Faculty of Medicine

Overview

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Qualifications

  • MD, University of Auckland, New Zealand
  • FRACP, Royal Australiasian College of Physicians
  • FRCPA, Royal College of Pathologists of Australasia
  • MBChB, University of Auckland New Zealand
  • BHB, University of Auckland NZ

Publications

  • AL-Kouba, Jane, Wilkinson, Andrew N., Starkey, Malcolm R., Rudraraju, Rajeev, Werder, Rhiannon B., Liu, Xiao, Law, Soi-Cheng, Horvat, Jay C., Brooks, Jeremy F., Hill, Geoffrey R., Davies, Janet M., Phipps, Simon, Hansbro, Philip M. and Steptoe, Raymond J. (2017) Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation. JCI Insight, 2 11: . doi:10.1172/jci.insight.85742

  • Forcade, Edouard, Paz, Katelyn, Flynn, Ryan, Griesenauer, Brad, Amet, Tohti, Li, Wei, Liu, Liangyi, Bakoyannis, Giorgos, Jiang, Di, Chu, Hong Wei, Lobera, Mercedes, Yang, Jianfei, Wilkes, David S., Du, Jing, Gartlan, Kate, Hill, Geoffrey R., MacDonald, Kelli P. A., Espada, Eduardo L., Blanco, Patrick, Serody, Jonathan S., Koreth, John, Cutler, Corey S., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Paczesny, Sophie and Blazar, Bruce R. (2017) An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition. JCI Insight, 2 12: . doi:10.1172/jci.insight.92111

  • Du, Jing, Paz, Katelyn, Flynn, Ryan, Vulic, Ante, Robinson, Tara M., Lineburg, Katie E., Alexander, Kylie A., Meng, Jingjing, Roy, Sabita, Panoskaltsis-Mortari, Angela, Loschi, Michael, Hill, Geoffrey R., Serody, Jonathan S., Maillard, Ivan, Miklos, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, MacDonald, Kelli P., Schacker, Timothy W., Luznik, Leo and Blazar, Bruce R. (2017) Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production. Blood, 129 18: 2570-2580. doi:10.1182/blood-2017-01-758854

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Markey, K.A., MacDonald, K.P.A. and Hill, G.R. (2013). Cytokines in Graft-versus-host Disease and Graft-versus-leukemia. In Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation (pp. 357-391) New York, NY, U.S.A.: Elsevier Inc.. doi:10.1016/B978-0-12-416004-0.00016-1

Journal Article

Conference Publication

  • Koyama, M., Kuns, R. D., Olver, S. D., Raffelt, N. C., Wilson, YA, Don, A. L. J., Lineburg, K. E., Robb, R. J., Markey, K. A., Varelias, A., Malissen, B., Hammerling, G. J., Bhat, P., Clouston, A. D., Engwerda, C. R., MacDonald, K. P. A. and Hill, G. R. (2012). Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd. In: Abstracts from the 2012 BMT Tandem Meetings. BMT Tandem Meeting, San Diego, CA, United States, (S362-S363). 01-05 Feburary 2012.

  • MacDonald, Kelli, Kuns, Rachel, Rowe, Vanessa, Don, Alistair, Morris, Edward, Thomas, Ranjeny and Hill, Geoffrey (2005). Nuclear translocation of ROB within host and donor antigen presenting cells is critical for the initiation and maintenance of acute graft-versus-host disease. In: Abstracts of the 47th Annual Meeting of the American Society of Hematology. 47th Annual Meeting of the American Society of Hematology, Atlanta, GA, United States, (137A-137A). 10 -13 December 2005.

  • Pai, S., O'Sullivan, B. J., MacDonald, K. P., Duggan, E., Gerondakis, S., Hill, G. and Thomas, R. (2005). The mechanism of inflammation in RelB deficient mice. In: Tissue Antigens: 'Genetics and The Immune Response' Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA and Immunogenetics Workshop. 35th Annual Scentific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, Australia, (507-507). 29 November - 2 December 2005.

  • MacDonald, K. P. A., Rowe, V., Thomas, R., Ferrera, J. L. M. and Hill, G. R. (2004). Cytokine expanded myeloid precursors function as regulatory antigen presenting cells and induce tolerance through IL-10 producing regulatory T cells. In: Immunology and Cell Biology. 22nd Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand, Canberra, Australia, (A15-A15). 31st March - 2nd April, 2004. doi:10.1111/j.1440-1711.2004.1259_2.x

  • MacDonald, K. P. A., Rowe, V., Thomas, R., Welply, J. K., Woulfe, S., Ferrara, J. L. M. and Hill, G. R. (2003). Progenipoietin-1 and G-CSF expand a novel CD40(neg) APC that induces transplant tolerance through IL-10 producing regulatory T cells. In: Abstracts of the 45th Annual Meeting of the American Society of Hematology. 45th Annual Meeting of the American Society of Hematology, San Diego, CA, United States, (191A-191A). 6 - 9 December 2003.

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

Completed Supervision