Operations Manager - National Biologics Facility
Deputy Director - ARC Training Centre for Biopharmaceutical Innovation
Research Areas: Discovery and engineering of antibodies for diagnostic or therapeutic uses
BScApp (Biotech) Honours Class I (1998) The University of Queensland
PhD (2008) The University of Queensland
Journal Article: A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants
Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085
Journal Article: Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies
Islam, Jiaul, Conroy, Paul, Fercher, Christian, Kim, Mijin, Yaari, Zvi, Jones, Martina, Bell, Toby D. M., Caradoc-Davies, Tom, Law, Ruby, Whisstock, James, Heller, Daniel, Mahler, Stephen and Corrie, Simon (2023). Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies. ACS Chemical Biology, 18 (8), 1863-1871. doi: 10.1021/acschembio.3c00303
Journal Article: Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies
Panagides, Nadya, Zacchi, Lucia F., Souza, Mitchell J. De, Morales, Rodrigo A. V., Karnowski, Alexander, Liddament, Mark T., Owczarek, Catherine M., Mahler, Stephen M., Panousis, Con, Jones, Martina L. and Fercher, Christian (2022). Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies. International Journal of Molecular Sciences, 23 (15) 8470, 8470. doi: 10.3390/ijms23158470
Development of reagents for blood product safety
(2023–2028) Australian Red Cross Society
(2023–2025) University of Melbourne
(2020–2021) Queensland Biomedical Voucher Program
Engineering Novel Theranostics for High Grade Glioma Through Site-Specific EphA2 Antibody Modification
Doctor Philosophy
(2022) Doctor Philosophy
(2021) Doctor Philosophy
Selection of antibodies to transiently expressed membrane proteins using phage display
Jones, Martina L., Mahler, Stephen M. and Kumble, Sumukh (2018). Selection of antibodies to transiently expressed membrane proteins using phage display. Antibody engineering. (pp. 179-195) edited by Damien Nevoltris and Patrick Chames. New York, NY, United States: Springer. doi: 10.1007/978-1-4939-8648-4_10
Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085
Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies
Islam, Jiaul, Conroy, Paul, Fercher, Christian, Kim, Mijin, Yaari, Zvi, Jones, Martina, Bell, Toby D. M., Caradoc-Davies, Tom, Law, Ruby, Whisstock, James, Heller, Daniel, Mahler, Stephen and Corrie, Simon (2023). Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies. ACS Chemical Biology, 18 (8), 1863-1871. doi: 10.1021/acschembio.3c00303
Panagides, Nadya, Zacchi, Lucia F., Souza, Mitchell J. De, Morales, Rodrigo A. V., Karnowski, Alexander, Liddament, Mark T., Owczarek, Catherine M., Mahler, Stephen M., Panousis, Con, Jones, Martina L. and Fercher, Christian (2022). Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies. International Journal of Molecular Sciences, 23 (15) 8470, 8470. doi: 10.3390/ijms23158470
He, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L., Goh, Justin B., Lyons, Nicholas J., Pearce, Lesley A., Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M,, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C., Perrin, Lewis C., Williams, Charlotte C., Puttick, Simon, Adams, Timothy E., Munro, Trent P., Hooper, John D. and Chetty, Naven (2021). Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer. Molecular Pharmaceutics, 18 (9) acs.molpharmaceut.1c00401, 3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401
In silico molecular dynamics of human glycophorin A (GPA) extracellular structure
Ekman, Serena, Flower, Robert, Mahler, Stephen, Gould, Alison, Barnard, Ross T., Hyland, Catherine, Jones, Martina, Malde, Alpeshkumar K. and Bui, Xuan T. (2021). In silico molecular dynamics of human glycophorin A (GPA) extracellular structure. Annals of Blood, 6 (June) 11. doi: 10.21037/aob-20-51
Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269
Recombinant antibody engineering enables reversible binding for continuous protein biosensing
Fercher, Christian, Jones, Martina L., Mahler, Stephen M. and Corrie, Simon R (2021). Recombinant antibody engineering enables reversible binding for continuous protein biosensing. ACS Sensors, 6 (3) acssensors.0c01510, 764-776. doi: 10.1021/acssensors.0c01510
Wardiana, Andri, Jones, Martina L., Mahler, Stephen M. and Howard, Christopher B. (2021). Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugate. Indonesian Journal of Pharmacy, 32 (1), 96-105. doi: 10.22146/ijp.1101
McGowan, Eunike C., Flower, Robert L., Jones, Martina L., Irving, David O., Barnard, Ross T., Hyland, Catherine A., Mahler, Stephen M. and Bui, Xuan T. (2020). Aggregates in blood filter chambers used from the plasma donations of anti-D donors: evaluation for monoclonal antibody discovery using phage display. Blood Transfusion , 19 (1), 64-72. doi: 10.2450/2020.0093-20
Phage display derived monoclonal antibodies: from bench to bedside
Alfaleh, Mohamed A., Alsaab, Hashem O., Mahmoud, Ahmad Bakur, Alkayyal, Almohanad A., Jones, Martina L., Mahler, Stephen M. and Hashem, Anwar M. (2020). Phage display derived monoclonal antibodies: from bench to bedside. Frontiers in Immunology, 11 1986, 1986. doi: 10.3389/fimmu.2020.01986
Playford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6
Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing
Raftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g
Islam, Jiaul, Riley, Blake T., Fercher, Christian, Jones, Martina L., Buckle, Ashley M., Howard, Christopher B., Cox, Rosalind P., Bell, Toby D. M., Mahler, Stephen and Corrie, Simon R. (2019). Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments. Analytical Chemistry, 91 (12), 7631-7638. doi: 10.1021/acs.analchem.9b00445
Jones, Martina L. (2019). Use of bacteriophage for discovery of therapeutically relevant antibodies against infectious diseases. Microbiology Australia, 40 (1), 33-36. doi: 10.1071/MA19007
Alfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015
Playford, Elliott, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2019). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a randomised, first-in-human phase 1 study. SSRN Electronic Journal. doi: 10.2139/ssrn.3457427
Wong, Kuan Y., Baron, Rebecca, Seldon, Therese A., Jones, Martina L., Rice, Alison M. and Munster, David J. (2018). CD83 antibody inhibits human B cell responses to antigen as well as dendritic cell-mediated CD4 T cell responses. Journal of Immunology, 200 (10), 3383-3396. doi: 10.4049/jimmunol.1700064
Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288
Alfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu and Mahler, Stephen M. (2017). Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models. Plos One, 12 (10) e0186137, e0186137. doi: 10.1371/journal.pone.0186137
Alfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B. and Mahler, Stephen M. (2017). Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning. Antibodies, 6 (3) 10, 1-19. doi: 10.3390/antib6030010
Lebani, Kebaneilwe, Jones, Martina L., Watterson, Daniel, Ranzoni, Andrea, Traves, Renee J., Young, Paul R. and Mahler, Stephen M. (2017). Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay. PLoS One, 12 (7) e0180669, e0180669. doi: 10.1371/journal.pone.0180669
Computational identification of antibody epitopes on the dengue virus NS1 protein
Jones, Martina L., Legge, Fiona S., Lebani, Kebaneilwe, Mahler, Stephen M., Young, Paul R., Watterson, Daniel, Treutlein, Herbert R. and Zeng, Jun (2017). Computational identification of antibody epitopes on the dengue virus NS1 protein. Molecules, 22 (4) 607, 607. doi: 10.3390/molecules22040607
Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10
Alsultan, Abdulkarim M., Chin, David Y., Howard, Christopher B., de Bakker, Christopher J., Jones, Martina L. and Mahler, Stephen M. (2016). Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10. Scientific Reports, 5 (37348) 37348, 37348. doi: 10.1038/srep37348
Biosimilars approved for treatment of inflammatory rheumatological diseases
Mahler, Stephen M., Wardiana, Andri, Jones, Martina L., De Bakker, Christopher J., Graham, Garry G. and Howard, Christopher B. (2016). Biosimilars approved for treatment of inflammatory rheumatological diseases. International Journal of Rheumatic Diseases, 19 (11), 1043-1048. doi: 10.1111/1756-185X.13037
Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Targeted nanomaterials: overcoming instability of antibody-nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies (Adv. Healthcare Mater. 16/2016). Advanced Healthcare Materials, 5 (16), 1994-1994. doi: 10.1002/adhm.201670084
Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263
Targeting membrane proteins for antibody discovery using phage display
Jones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y. and Mahler, Stephen M. (2016). Targeting membrane proteins for antibody discovery using phage display. Scientific Reports, 6 (1) 26240, 26240. doi: 10.1038/srep26240
Biosensing made easy with PEG-targeted bi-specific antibodies
Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A
Seldon, T. A., Pryor, R., Palkova, A., Jones, M. L., Verma, N. D., Findova, M., Braet, K., Sheng, Y., Fan, Y., Zhou, Y. Y., Marks, J. D., Munro, T., Mahler, S. M., Barnard, R. T., Fromm, P. D., Silveira, P. A., Elgundi, Z., Ju, X., Clark, G. J., Bradstock, K. F., Munster, D. J. and Hart, D. N. J. (2015). Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation.. Leukemia, 30 (3), 692-700. doi: 10.1038/leu.2015.231
Nanocell targeting using engineered bispecific antibodies.
Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952
Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy - future prospects
Goodall, Stephen, Jones, Martina L. and Mahler, Stephen (2014). Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy - future prospects. Journal of Chemical Technology and Biotechnology, 90 (7), 1169-1176. doi: 10.1002/jctb.4555
Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells
Buecheler, Jakob W., Howard, Christopher B., de Bakker, Christopher J., Goodall, Stephen, Jones, Martina L, Win, Thinzar, Peng, Tao, Tan, Cher Heng, Chopra, Akhil, Mahler, Stephen M and Lim, Sierin (2014). Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells. Journal of Chemical Technology and Biotechnology, 90 (7), 1230-1236. doi: 10.1002/jctb.4545
An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer
Goodall, Stephen, Howard, Christopher B., Jones, Martina L., Munro,Trent, Jia, Zhongfan, Monteiro, Michael J and Mahler, Stephen (2014). An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer. Journal of Chemical Technology and Biotechnology, 90 (7), 1222-1229. doi: 10.1002/jctb.4509
Leow, Chiuan Herng, Jones, Martina, Cheng, Qin, Mahler, Strphen and McCarthy, James (2014). Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2. Malaria Journal, 13 (1) 277. doi: 10.1186/1475-2875-13-277
Song, Michael, Raphaelli, Kristin, Jones, Martina L., Aliabadi-Zadeh, Khosrow, Leung, Kar Man, Crowley, David, Hughes, Benjamin, Mahler, Stephen, Gray, Peter P., Huang, Edwin P. and Chin, David Y. (2011). Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening. Journal of Chemical Technology and Biotechnology, 86 (7), 935-941. doi: 10.1002/jctb.2618
Improved protein-A separation of Vh3 Fab from Fc after papain digestion of antibodies
Seldon, Therese A., Hughes, Karen E., Munster, David J., Chin, David Y. and Jones, Martina L. (2011). Improved protein-A separation of Vh3 Fab from Fc after papain digestion of antibodies. Journal of Biomolecular Techniques, 22 (2), 50-52.
A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies
Jones, Martina L., Seldon, Therese, Smede, Matthew, Linville, Ashleigh, Chin, David Y., Barnard, Ross, Mahler, Stephen M., Munster, David, Hart, Derek, Gray, Peter P. and Munro, Trent P. (2010). A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies. Journal of Immunological Methods, 354 (1-2), 85-90. doi: 10.1016/j.jim.2010.02.001
Jones, Martina L. and Barnard, Ross (2007). Use of chimeric antibodies as positive controls in an enzyme-linked immunosorbent assay for diagnosis of scrub typhus (infection by orientia tsutsugamushi). Clinical and Vaccine Immunology, 14 (10), 1307-1310. doi: 10.1128/CVI.00114-07
Chimerization of multiple antibody classes using splice overlap extension PCR
Jones, M. L. and Barnard, R. T. (2005). Chimerization of multiple antibody classes using splice overlap extension PCR. Biotechniques, 38 (2), 181-182. doi: 10.2144/05382BM01
Tetrahydrofolates are greatly stabilized by binding to bovine milk folate-binding protein
Jones, M. L. and Nixon, P. F. (2002). Tetrahydrofolates are greatly stabilized by binding to bovine milk folate-binding protein. Journal of Nutrition, 132 (9), 2690-2694. doi: 10.1093/jn/132.9.2690
Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina and Bui, Xuan (2019). Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.353
In silico model for glycophorin a (GPA) structure
Ekman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina, Treutlein, Herbert and Bui, Xuan (2019). In silico model for glycophorin a (GPA) structure. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.352
In silico modelling of glycophorin MNS system blood group antigens
Flower, R., Ekman, S., Mahler, S., Jones, M., Malde, A. K. and Bui, X. (2019). In silico modelling of glycophorin MNS system blood group antigens. In: ANZSBT, Perth, Australia, (24-25). 20-23 October 2019.
Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines
Saunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02
CD83 Expression On Human Immune Cells as a Target for Immunosuppression
Hart, D. N. J., Elgundi, Z., Ju Xinsheng, Verma, N. D., Silveira, P. A., Fromm, P. D., Alingcastre, R., Munster, D. J., Seldon, T. A., Sheng, Y., Jones, M. L., Munro, T. P., Mahler, S., Barnard, R. T., Vu, P. A., Lo, K., Shahin, K., Larsen, S., Bradstock, K. and Clark, G. J. (2015). CD83 Expression On Human Immune Cells as a Target for Immunosuppression. 33rd Annual Scientific Meeting of the Transplantation Society of Australia and new Zealand, Canberra, ACT Australia, 21-23 June 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/icb.2015.75
Hart, Derek N. J., Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Hsu, Blake, Munster, David J., Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Al, Lo, Tsun Ho, Shahin, Kifah, Larsen, Stephen Robert, Bradstock, Kenneth and Clark, Georgina (2015). Characterisation of human CD83 expression on immune cells and their targeting with CD83 antibodies to prevent graft versus host disease in allogeneic haematopoietic cell transplantation. 57th Annual Meeting of the American Society of Hematology, Orlando, FL, United States, 5-8 Dec 2015. WASHINGTON: AMER SOC HEMATOLOGY.
Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Munster, David, Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Ai, Lo, Tsun Ho, Shahin, Kifah, Clark, Georgina, Larsen, Stephen, Bradstock, Kenneth and Hart, Derek (2015). Human Cd83 Expression On Immune Cells Validates Anti-Cd83 Prophylaxis to Prevent Graft Versus Host Disease in Allogeneic Haematopoietic Cell Transplantation.. 14th Transplantation Science Symposium of the Transplantation-Society (TSS), Lorne, Australia, 11-13 November 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Verma, Nirupama D., Munster, David, Seldon, Therese, Sheng, Yong Hua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Phi Ai, Lo, Kevin, Shahin, Kifah, Elgundi, Zehra, Silveira, Pablo, Fromm, Phillip D., Clark, Georgina J., Larsen, Stephen, Bradstock, Kenneth and Hart, Derek N. J. (2015). The Human Monoclonal Antibody 3C12C, Targeting Activated Dendritic Cells Is a Potential New Immunosuppressive Agent. BMT Tandem Meetings, San Diego, CA United States, 11-15 February 2015. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.bbmt.2014.11.527
Hart, D, Verma, N., Seldon, T, Sheng, Y., Pryor, R., Palkova, A., Findova, M., Jones, M., Munro, T., Mahler, S., Braet, K., Barnard, R., Marks, J., Coley, A., Fan, F., Zhou, Y., Vu, P, Lo, K., Shahin, K., Elgundi, Z., Silveira, P., Fromm, P., Clark, G., Larsen, S., Bradstock, K. and Munster, D. (2014). The Monoclonal Antibody 3C12C, Targeting CD83 Is a T Cell Sparing, Potential New Immunosuppressive Agent. 2014 World Transplant Congress, San Francicso Ca, 26 - 31 July 2014. Malden, MA United States: Wiley-Blackwell Publishing, Inc.. doi: 10.1111/ajt.12888
Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease
Hart, D, Seldon, T, Jones, M, Sheng, Y, Palkova, A, Cullup, H, Munro, T, Sinfield, L, Rice, AM, Wilson, J, Gray, P, Barnard, R, Mahler, S and Munster, D (2009). Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease. 51st Annual Meeting of the American Society of Hematology, New Orleans LA, 5-8 December 2009. Washington, D.C.: American Society of Hematology.
Jones, ML, Treloar, T and Nixon, PF (2003). Dietary interactions influence the effects of bovine folate-binding protein on the bioavailability of tetrahydrofolates in rats. USA: American Society for Nutritional Sciences. doi: 10.1093/jn/133.2.489
Availability of folate bound to folate-binding protein: Environmental effects
Jones, M. L., Treloar, W. and Nixon, P. F. (2001). Availability of folate bound to folate-binding protein: Environmental effects. 2nd Dairy Industry Association of Australia World Series of Dairy Science Conference, Australia, 2001. Melbourne: Dairy Industry Association of Australia.
Milk folate-binding protein; ligand-binding properties and polymerization properties
Jones, MD, Hutchinson, ML and Nixon, PF (2000). Milk folate-binding protein; ligand-binding properties and polymerization properties. Dairy Ingredient Science 2000 Conference, Melbourne, Australia, 2000. Melbourne,VIC: Dairy Industry Association of Australia.
Stability of labile folate is enhanced by binding milk folate-binding protein
Hutchinson, M. L., Jones, M. and Nixon, P. F. (2000). Stability of labile folate is enhanced by binding milk folate-binding protein. Dairy Ingredient Science 2000 Conference, Melbourne, Australia, 28-30 Jun, 2000. Melbourne, Australia: Dairy Industry Association of Australia.
Anti-CD83 antibodies and use thereof
Seldon, T. A., Munster, D. J., Hart, D. N., Jones, M. L., Munro, T. P., Mahler, S. M., Zhou, Y. and Marks, D. (2013). Anti-CD83 antibodies and use thereof.
Jones, Martina (2008). Engineered Antibodies. Production and application of chimeric and single-chain antibodies as positive controls in the diagnosis of infectious diseases by ELISA.. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland.
Development of reagents for blood product safety
(2023–2028) Australian Red Cross Society
(2023–2025) University of Melbourne
(2020–2021) Queensland Biomedical Voucher Program
Manufacture of two anti-midkine antibodies for potential cancer and inflammatory disease therapy'
(2019–2020) Department of State Development QLD
Cyto-Mine to accelerate Cell Line Development for Vaccines and Biopharmaceuticals
(2019) UQ Major Equipment and Infrastructure
ARC Training Centre for Biopharmaceutical Innovation
(2017–2023) ARC Industrial Transformation Training Centres
Affinity Maturation of Anti-Lipopolysaccharide Antibody
(2017–2018) Innovation Connections
Platform technology for the discovery of antibodies to membrane proteins using cell-free expression
(2017) UQ Early Career Researcher
Special Access m102.4 Antibody
(2016–2023) Queensland Health
ZZ Biotech Research Development
(2016–2018) ZZ Biotech Pty Ltd
(2014–2023) Therapeutic Innovation Australia Limited
Safety assessment of anti-hendra virus antibody in humans
(2013–2015) Queensland Health
The Manufacture of a Recombinant Antibody
(2013–2014) UniQuest Pty Ltd
(2012–2015) ARC Linkage Projects
Engineering Novel Theranostics for High Grade Glioma Through Site-Specific EphA2 Antibody Modification
Doctor Philosophy — Principal Advisor
Other advisors:
(2022) Doctor Philosophy — Principal Advisor
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(2021) Doctor Philosophy — Principal Advisor
Other advisors:
Structural Studies of MNS Glycophorins to Guide the Discovery of Monoclonal Antibodies
(2021) Doctor Philosophy — Principal Advisor
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(2021) Doctor Philosophy — Principal Advisor
Other advisors:
(2023) Doctor Philosophy — Associate Advisor
Other advisors:
Development of monoclonal antibodies against human neutrophil antigen 3 (HNA-3)
(2022) Doctor Philosophy — Associate Advisor
Other advisors:
Development of novel bioconjugation strategies for creating cancer-targeting nanomaterials
(2020) Doctor Philosophy — Associate Advisor
Other advisors:
Developing antibody-based therapy to treat acute Epstein-Barr virus infection and prevent its associated diseases
(2019) Doctor Philosophy — Associate Advisor
(2019) Doctor Philosophy — Associate Advisor
Isolation and development of antibodies for active targeting of nanocells for cancer therapy
(2018) Doctor Philosophy — Associate Advisor
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Development and Application of Novel Biosensor Technologies
(2017) Doctor Philosophy — Associate Advisor
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Antibody Discovery for Development of a Serotyping Dengue Virus NS1 Capture Assay
(2015) Doctor Philosophy — Associate Advisor
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(2015) Doctor Philosophy — Associate Advisor
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Development of monoclonal antibodies as tools for analysis of PTPRJ function.
(2015) Doctor Philosophy — Associate Advisor
Other advisors:
(2015) Doctor Philosophy — Associate Advisor
Other advisors: