Associate Professor Margaret Cummings

Academic Title-Associate Professor

School of Biomedical Sciences
Faculty of Medicine



View all Publications


Book Chapter

  • Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. In Sandra J. Shin (Ed.), A comprehensive guide to core needle biopsies of the breast (pp. 803-817) Cham, Switzerland: Springer. doi:10.1007/978-3-319-26291-8

  • Saunus, Jodi M., McCart-Reed, Amy, Momeny, Majid, Cummings, Margaret and Lakhani, Sunil R. (2013). Breast cancer heterogeneity in primary and metastatic disease. In Aamir Ahmad (Ed.), Breast Cancer Metastasis and Drug Resistance: Challenges and Progress (pp. 65-96) New York, NY, USA: Springer. doi:10.1007/978-1-4614-5647-6

  • Cummings, M. C., Winterford, C. M. and Walker, N. I. (1997). Apoptosis. In Stephen S. Sternberg (Ed.), Histology for pathologists 2nd ed. (pp. 3-21) Philadelphia, PA United States: Lippencott-Raven.

Journal Article

  • Hendry, Shona, Pang, Jia-Min B., Byrne, David J., Lakhani, Sunil R., Cummings, Margaret C., Campbell, Ian G., Mann, G. Bruce, Gorringe, Kylie L. and Fox, Stephen B. (2017) Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features. Clinical Cancer Research, 23 17: 5210-5217. doi:10.1158/1078-0432.CCR-17-0743

  • Pang, Jia-Min B., Savas, Peter, Fellowes, Andrew P., Arnau, Gisela Mir, Kader, Tanjina, Vedururu, Ravikiran, Hewitt, Chelsee, Takano, Elena A., Byrne, David J., hoong, David Y. H., Millar, Ewan K. A., Lee, C. Soon, O'Toole, Sandra A., Lakhani, Sunil R., Cummings, Margaret C., Mann, G. Bruce, Campbell, Ian G., Dobrovic, Alexander, Loi, Sherene, Gorringe, Kylie L. and Fox, Stephen B. (2017) Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer. Modern Pathology, 30 7: 952-963. doi:10.1038/modpathol.2017.21

  • Packer, Leisl M., Geng, Xinyan, Bonazzi, Vanessa F., Ju, Robert J., Mahon, Clare E., Cummings, Margaret C., Stephenson, Sally-Anne and Pollock, Pamela M. (2017) PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers. Molecular Cancer Therapeutics, 16 4: 637-648. doi:10.1158/1535-7163.MCT-16-0415

  • Cummings, M. C., Greaves, J., Shukor, R. A., Perkins, G. and Ross, J. (2017) Technical proficiency in cytopathology: assessment through external quality assurance. Cytopathology, 28 2: 149-156. doi:10.1111/cyt.12373

  • Field, Sarah, Uyttenhove, Catherine, Stroobant, Vincent, Cheou, Paméla, Coutelier, Jean-Paul, Simpson, Peter T., Cummings, Margaret C., Saunus, Jodi M., Reid, Lynne E., Kutasovic, Jamie R., McNicol, Anne Marie, Kim, Ba Reun, Kim, Jae Ho, Lakhani, Sunil R., Neville, A. Munro, Van Snick, Jacques and Jat, Parmjit S. (2016) Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer. International Journal of Cancer, 138 8: 1959-1970. doi:10.1002/ijc.29946

  • Antill, Yoland C., Dowty, James G., Win, Aung Ko, Thompson, Tina, Walsh, Michael D., Cummings, Margaret C., Gallinger, Steven, Lindor, Noralane M., Le Marchand, Loic, Hopper, John L., Newcomb, Polly A., Haile, Robert W., Church, James, Tucker, Katherine M., Buchanan, Daniel D., Young, Joanne P., Winship, Ingrid M. and Jenkins, Mark A. (2015) Lynch syndrome and cervical cancer. International Journal of Cancer, 137 11: 2757-2761. doi:10.1002/ijc.29641

  • Saunus, Jodi M., Quinn, MIchael C. J., Patch, Ann-Marie, Pearson, John V., Bailey, Peter J., Nones, Katia, McCart Reed, Amy E., Miller, David, Peter J. Wilson, Al-Ejeh, Fares, Mariasegaram, Mythily, Lau, Queenie, Withers, Teresa, Jeffree, Rosalind L., Reid, Lynne E., Da Silva, Leonard, Matsika, Admire, Niland, Colleen M., Cummings, Margaret C., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Anderson, Matthew J., Fink, J. Lynn, Holmes, Oliver, Kazakoff, Stephen, Leonard, Conrad, Newell, Felicity, Taylor, Darrin, Wood, Scott, Xu, Qinying, Kassahn, Karin S., Narayanan, Vairavan, Taib, Nur Aishah, Teo, Soo-Hwang, Chow, Yock Ping, kConFab, Jat, Parmjit S., Brandner, Sebastian, Flanagan, Adrienne M., Khanna, KumKum, Chenevix-Trench, Georgia, Grimmond, Sean M., Simpson, Peter T., Waddell, Nicola and Lakhani, Sunil R. (2015) Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance. Journal of Pathology, 237 3: 363-378. doi:10.1002/path.4583

  • Cummings, Margaret C., Marquart, Louise, Pelecanos, Anita M., Perkins, Gail, Papadimos, David, O'Rourke, Peter and Ross, Jennifer A. (2015) Which are more correctly diagnosed: conventional Papanicolaou smears or ThinPrep samples? A comparative study of 9 tears of external quality-assurance testing. Cancer Cytopathology, 123 2: 108-116. doi:10.1002/cncy.21498

  • Generali, D., Buffa, F. M., Deb, S., Cummings, M., Reid, L. E., Taylor, M., Andreis, D., Allevi, G., Ferrero, G., Byrne, D., Martinotti, M., Bottini, A., Harris, A. L., Lakhani, S. R. and Fox, S. B. (2014) COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer, 111 1: 46-54. doi:10.1038/bjc.2014.236

  • Kutasovic, Jamie R., Sim, Sarah Y. M., McCart Reed, Amy E., Cummings, Margaret C. and Simpson, Peter T. (2014) Intratumour heterogeneity in the progression to breast cancer metastasis. Cancer Forum, 38 2: 138-142.

  • Vuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014) Molecular classification of breast cancer. Virchows Archiv, 465 1: 1-14. doi:10.1007/s00428-014-1593-7

  • Cummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014) Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 1: 23-31. doi:10.1002/path.4288

  • Tilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014) Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 2: 385-392. doi:10.1007/s10549-013-2798-1

  • Buchanan, Daniel D., Tan, Yen Y., Walsh, Michael D., Clendenning, Mark, Metcalf, Alexander M., Ferguson, Kaltin, Arnold, Sven T., Thompson, Bryony A., Lose, Felicity A., Parsons, Michael T., Walters, Rhiannon J., Pearson, Sally-Ann, Cummings, Margaret, Oehler, Martin K., Blomfield, Penelope B., Quinn, Michael A., Kirk, Judy A., Stewart, Colin J., Obermair, Andreas, Young, Joanne P., Webb, Penelope M. and Spurdle, Amanda B. (2014) Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. Journal of Clinical Oncology, 32 2: 90-100. doi:10.1200/JCO.2013.51.2129

  • Walsh, Michael D., Cummings, Margaret C., Pearson, Sally-Ann, Clendenning, Mark, Walters, Rhiannon J., Nagler, Belinda, Hopper, John L., Jenkins, Mark A., Suthers, Graeme K., Goldblatt, Jack, Tucker, Kathy, Gattas, Michael R., Arnold, Julie L., Parry, Susan, Macrae, Finlay A., McGuckin, Michael A., Young, Joanne P. and Buchanan, Daniel D. (2013) Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. Modern Pathology, 26 7: 944-954. doi:10.1038/modpathol.2012.232

  • Hosein, Abdel Nasser, Song, Sarah, McCart Reed, Amy E., Jayanthan, Janani, Reid, Lynne E., Kutasovic, Jamie R., Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R., Chenevix-Trench, Georgia and Simpson, Peter T. (2013) Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis. Laboratory Investigation, 93 6: 701-710. doi:10.1038/labinvest.2013.54

  • Waldron, Levi, Ogino, Shuji, Hoshida, Yujin, Shima, Kaori, Reed, Amy E. McCart, Simpson, Peter T., Baba, Yoshifumi, Nosho, Katsuhiko, Segata, Nicola, Vargas, Ana Cristina, Cummings, Margaret C., Lakhani, Sunil R., Kirkner, Gregory J., Giovannucci, Edward, Quackenbush, John, Golub, Todd R., Fuchs, Charles S., Parmigiani, Giovanni and Huttenhower, Curtis (2012) Expression profiling of archival tumors for long-term health studies. Clinical Cancer Research, 18 22: 6136-6146. doi:10.1158/1078-0432.CCR-12-1915

  • Bilous, Michael, Adrienne L. Morey, Armes, Jane E., Bell, Richard, Button, Peter H., Cummings, Margaret C., Fox, Stephen B., Francis, Glenn D., Waite, Brigid, McCue, Glenda, Raymond, Wendy A., Robbins, Peter D. and Farshid, Gelareh (2012) Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program. Breast Cancer Research and Treatment, 134 2: 617-624. doi:10.1007/s10549-012-2093-6

  • Fox, Stephen B., Kumarasinghe, Marian Priyanthi, Armes, Jane E., Bilous, Michael, Cummings, Margaret C., Farshid, Gelareh, Fitzpatrick, Nicole, Francis, Glenn D., McCloud, Philip I., Raymond, Wendy and Morey, Adrienne (2012) Gastric HER2 testing study (GaTHER): An evaluation of gastric/ gastroesophageal junction cancer testing accuracy in Australia. American Journal of Surgical Pathology, 36 4: 577-582. doi:10.1097/PAS.0b013e318244adbb

  • McCart Reed, Amy E., Cummings, Margaret C., Lakhani, Sunil R. and Simpson, Peter T. (2012) Molecular pathology of pre-invasive breast disease in the screening setting: Application in diagnosis and management. Diagnostic Histopathology, 18 2: 64-69. doi:10.1016/j.mpdhp.2011.11.006

  • Alizart, Michelle, Saunus, Jodi, Cummings, Margaret and Lakhani, Sunil R. (2012) Molecular classification of breast carcinoma. Diagnostic Histopathology, 18 3: 97-103. doi:10.1016/j.mpdhp.2011.12.003

  • Cummings, M.C., Waters, B.A. and Rourke, P.K.O. (2011) Breast fine needle aspiration cytology: a review of current practice in Australasia. Cytopathology, 22 4: 269-275. doi:10.1111/j.1365-2303.2010.00788.x

  • Ramus, Susan J., Kartsonaki, Christiana, Gayther, Simon A., Pharoah, Paul D. P., Sinilnikova, Olga M., Beesley, Jonathan, Chen, Xiaoqing, McGuffog, Lesley, Healey, Sue, Couch, Fergus J., Wang, Xianshu, Fredericksen, Zachary, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Roversi, Gaia, Barile, Monica, Viel, Alessandra, Allavena, Anna, Ottini, Laura, Papi, Laura, Gismondi, Viviana, Capra, Fabio, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Andrulis, Irene L., Glendon, Gord, Ozcelik, Hilmi, OCGN, Thomassen, Mads, Gerdes, Anne-Marie, Kruse, Torben A., Cruger, Dorthe, Jensen, Uffe Birk, Caligo, Maria Adelaide, Olsson, Hakan, Kristoffersson, Ulf, Lindblom, Annika, Arver, Brita, Karlsson, Per, Askmalm, Marie Stenmark, Borg, Ake, Neuhausen, Susan L., Ding, Yuan Chun, Nathanson, Katherine L., Domchek, Susan M., Jakubowska, Anna, Lubinski, Jan, Huzarski, Tomasz, Byrski, Tomasz, Gronwald, Jacek, Bohdan Gorski, Cybulski, Cezary, Debniak, Tadeusz, Osorio, Ana, Duran, Mercedes, Tejada, Maria-Isabel, Benitez, Javier, Hamann, Ute, Rookus, Matti A., Verhoef, Senno, Tilanus-Linthorst. Madeleine A., Vreeswijk, Maaike P., Bodmer, Daniel, Ausems, Margreet G. E. M., van Os, Theo A., Asperen, Christi J., Blok, Marinus J., Meijers-Heijboer, Hanne E. J., HEBON, EMBRACE, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Dunning, Alison M., Evans, D. Gareth, Eeles, Ros, Pichert, Gabriella, Cole, Trevor, Hodgson, Shirley, Brewer, Carole, Morrison, Patrick J., Porteous, Mary, Kennedy, M. John, Rogers, Mark T., Side, Lucy E., Donaldson, Alan, Gregory, Helen, Godwin, Andrew, Stoppa-Lyonnet, Dominique, Moncourtier, Virginie, Castera, Laurent, Mazoyer, Sylvie, Barjhoux, Laure, Bonadona, Valerie, Leroux, Dominique, Faivre, Laurence, Lidereau, Rosette, Nogues, Catherine, Bignon, Yves-Jean, Prieur, Fabienne, Collonge-Rame, Marie-Agnes, Venat-Bouvet, Laurence, Fert-Ferrer, Sandra, GEMO Study Collaborators, Miron, Alex, Buys, Saundra S., Hopper, John L., Daly, Mary B., John, Esther M., Terry, Mary Beth, Goldgar, David, BCFR, Hansen, Thomas V. O., Jonson, Lars, Ejlertsen, Bent, Agnarsson, Bjarni A., Offit, Kenneth, Kirchhoff, Tomas, Vijai, Joseph, Dutra-Clarke, Ana V. C., Przybylo, Jennifer A., Montagna, Marco, Casella, Cinzia, Imyanitov, Evgeny N., Janavicius, Ramunas, Blanco, Ignacio, Lazaro, Conxi, Moysich, Kirsten B., Karlan, Beth Y., Gross, Jenny, Beattie, Mary S., Schmutzler, Rita, Wappenschmidt, Barbara, Meindl, Alfons, Ruehl, Ina, Fiebig, Britta, Sutter, Christian, Arnold, Norbert, Deissler, Helmut, Varon-Mateeva, Raymonda, Kast, Karin, Niederacher, Dieter, Gadzicki, Dorothea, Caldes, Trinidad, de la Hoya, Miguel, Nevanlinna, Heli, Aittomaki, Kristiina, Simard, Jacques, Soucy, Penny, kConFab Investigators, Spurdle, Amanda B., Holland, Helene, Chenevix-Trench, Georgia, Easton, Douglas F., Antoniou, Antonis C., on behalf of Consortium of Investigators of Modifiers of BRCA1/2, Brown, Melissa, Cummings, Margaret and Lakhani, Sunil (2011) Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institiute, 103 2: 105-116. doi:10.1093/jnci/djq494

  • Cummings, Margaret C., Chambers, Rachael, Simpson, Peter T. and Lakhani, Sunil R. (2011) Molecular classification of breast cancer: Is it time to pack up our microscopes?. Pathology, 43 1: 1-8. doi:10.1097/PAT.0b013e328341e0b5

  • Balleine, Rosemary L., Provan, Pamela J., Pupo, Gulietta M., Pathmanathan, Nirmala, Cummings, Margaret, Farshid, Gelareh, Salisbury, Elizabeth L., Bilous, A. Michael, Byth, Karen and Mann, Graham J. (2010) Familial concordance of breast cancer pathology as an indicator of genotype in multiple-case families. Genes, Chromosomes and Cancer, 49 12: 1082-1094. doi:10.1002/gcc.20816

  • Shield, Paul W., Finnimore, Jo, Cummings, Margaret and Wright, R. Gordon (2010) Performance measures for Australian laboratories reporting cervical cytology: A decade of data 1998-2008. Pathology, 42 7: 623-628. doi:10.3109/00313025.2010.520308

  • Antoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki,Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey, Caron, Olivier, Hardouin, Agnes, Berthet, Pascaline, Hogervorst, Frans B. L., Rookus, Matti A., Jager, Agnes, van den Ouweland, Ans, Hoogerbrugge, Nicoline, van der Luijt, Rob B., Meijers-Heijboer, Rob B., Gomez Garcia, Encarna B., Devilee, Peter, Vreeswijk, Maaike P. G., Lubinski, Jan, Jakubowska, Anna, Gronwald, Jacek, Huzarski, Tomasz, Byrski, Tomasz, Gorski, Bohdan, Cybulski, Cezary, Spurdle, Amanda B., Holland, Helene, Goldgar, David E., John, Esther M., Hopper, John L., Southey, Melissa, Buys,Saundra S., Daly,Mary B., Terry, Mary-Beth, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Meindl, Alfons, Preisler-Adams, Sabine, Arnold, Norbert, Niederacher, Dieter, Sutter, Christian, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy, Blum, Joanne L., Piedmonte, Marion, Rodriguez, Gustavo C., Wakeley, Katie, Boggess, John F., Basil, Jack, Blank, Stephanie V., Friedman, Eitan, Kaufman, Bella, Laitman, Yael, Milgrom, Roni, Andrulism, Irene L., Glendon, Gord, Ozcelik, Hilmi, Kirchhoff, Tomas, Vijai, Joseph, Gaudet, Mia M., Altshuler, David, Guiducci, Candace, Loman, Niklas, Harbst, Katja, Rantala, Johanna, Ehrencrona, Hans, Gerdes, Anne-Marie, Thomassen, Mads, Sunde, Lone, Peterlongo, Paolo, Manoukian, Siranoush, Bonanni, Bernardo, Viel, Alessandra, Radice, Paolo, Caldes, Trinidad, de la Hoya, Miguel, Singer, Christian F., Fink-Retter, Anneliese, Greene,Mark H., L. Mai, Phuong, Loud, Jennifer T., Guidugli, Lucia, Lindor, Noralane M., Hansen, Thomas V. O., Nielsen, Finn C., Blanco, Ignacio, Lazaro,Conxi, Garber, Judy, Ramus, Susan J., Gayther, Simon A., Phelan, Catherine, Narod, Stephen, Szabo, Csilla I ., Benitez, Javier, Osorio, Ana, Nevanlinna,Heli, Heikkinen, Tuomas, Caligo, Maria A., Beattie,Mary S., Hamann,Ute, Godwin, Andrew K., Montagna, Marco, Casella, Cinzie, Neuhausen, Susan L., Karlan, Beth Y., Tung, Nadine, Toland, Amanda E ., Weitzel, Jeffrey, Olopade, Olofunmilayo, Simard, Jacques, Soucy, Penny, Rubinstein, Wendy S., Arason, Adalgeir, Rennert, Gad, Martin, Nicholas G., Montgomery, Grant W., Chang-Claude,Jenny, Flesch-Janys, Dieter, Brauch, Hiltrud, Severi, Gianluca, Baglietto, Laura, Cox, Angela, Cross, Simon S., Miron, Penelope, Gerty, Sue M, Tapper, William, Yannoukakos, Drakoulis, Fountzilas, George, Fasching, Peter A., Beckmann, Matthias W., dos Santos Silva, Isabel, Peto, Julian, Lambrechts, Diether, Paridaens, Robert, Rudiger, Thomas, Forsti, Asta, Winqvist, Robert, Pylkas, Katri, Diasio, Robert B., Lee, Adam M., Eckel-Passow, Jeanette, Vachon, Celine, Blows, Fiona, Driver, Kristy, Dunning, Alison, Pharoah, Paul P. D., Offit, Kenneth, Pankratz, V. Shane, Hakonarson, Hakon, Chenevix-Trench, Georgia, Easton,Douglas F., Couch, Fergus J., EMBRACE, GEMO Study Collaborators, HEBON, kConFab, SWE-BRCA, MOD SQUAD, GENICA, Brown, Melissa, Cummings, Margaret and Lakhani, Sunil (2010) A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nature Genetics, 42 10: 885-892. doi:10.1038/ng.669

  • Mia M. Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M. Korn, Candace Guiducci, Ayellet V. Segre, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M. Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B. L. Hogervorst, Matti a. Rookus, J. Margriet Collee, Nicoline Hoogerbrugge, Kees E. P. van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone, Linda Van Le, Stephanie V. Blank, Trinidad Caldes, Miguel de la Hoya, Heli Nevanlinna, Kristiina Aittomaki, Conxi Lazaro, Ignacio Blanco, Adalgeir Arason, Oskar T. Johannsson, Rosa B. Barkardottir, Peter Devilee, Olofunmilayo I. Olopade, Susan L. Neuhausen, Xianshu Wang, Zachary S. Fredericksen, Paolo Peterlongo, Siranoush Manoukian, Monica Barile, Alessandra Viel, Paolo Radice, Catherine M. Phelan, Steven Narod, Gad Rennert, Flavio Lejbkowicz, Anath Flugelman, Irene L. Andrulis, Gord Glendon, Hilmi Ozcelik, OCGN, Amanda E. Toland, Marco Montagna, Emma D'Andrea, Eitan Friedman, Yael Laitman, Ake Borg, Mary Beattie, Susan J. Ramus, Susan M. Domchek, Katherine L. Nathanson, Tim Rebbeck, Spurdle, Amanda B., Chen, Xiaoqing, Helene Holland, kConFab, Esther M. John, John L. Hopper, Saundra s. Buys, Mary B. Daly, Melissa C. Southey, Mary Beth Terry, Nadine Tung, Thomas V. Overeem Hansen, Finn C. Nielsen, Mark H. Greene, Phuong L. Mai, Ana Osorio, Mercedes Duran, Rauel Andres, Javier Benitez, Jeffrey N. Weitzel, Judy Garber, Susan Peock, EMBRACE, Ute Hamann, Margaret Cook, Clare Oliver, Debra Frost, Radka Platte, D. Gareth Evans, Fiona Lalloo, Ros Eeles, Louise Izatt, Lisa Walker, Jacqueline Eason, Rita K. Schmutzler, Julian Barwell, Andrew K. Godwin, Barbara Wappenschmidt, Stefanie Engert, Norbert Arnold, Bert Gold, Michael Dean, Robert J. Klein, Dorothea Gadzicki, Fergus J. Couch, Chenevix-Trench, Georgia, Douglas F. Easton, Mark J. Daly, Antonis C. Antoniou, David M. Altshuler, Kenneth Offit, Brown, Melissa, Cummings, Margaret and Lakhani, Sunil (2010) Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genetics, 6 10: e1001183-1-e1001183-12. doi:10.1371/journal.pgen.1001183

  • Wang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, Tarrell, Robert, Karaus, Mary, McGuffog, Lesley, Pharaoh, Paul D.P., Ponder, Bruce A.J., Dunning, Alison M., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, EMBRACE, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Houdayer, Claude, GEMO, Hogervorst, Frans B.L., Hooning, Maartje J., Ligtenberg, Marjolijn J., HEBON, Spurdle, Amanda, Chenevix-Trench, Georgia, kConFab, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph, Meindl, Alfons, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Singer, Christian F., Gschwantler-Kaulich, Daphne, Dressler, Catherina, Fink, Anneliese, Szabo, Csilla I., Zikan, Michal, Foretova, Lenka, Claes, Kathleen, Thomas, Gilles, Hoover, Robert N., Hunter, David J., Chanock, Stephen J., Easton, Douglas F., Antoniou, Antonis C., Couch, Fergus J., Brown, Melissa, Cummings, Margaret and Lakhani, Sunil (2010) Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics, 19 14: 2886-2897. doi:10.1093/hmg/ddq174

  • Walsh, MD, Buchanan, DD, Cummings, MC, Pearson, SA, Arnold, ST, Clendenning, M, Walters, R, McKeone, DM, Spurdle, AB, Hopper, JL, Jenkins, MA, Phillips, KD, Suthers, GK, George, J, Goldblatt, J, Muir, A, Tucker, K, Pelzer, E, Gattas, MR, Woodall, S, Parry, S, Macrae, FA, Haile, RW, Baron, JA, Potter, JD, Le Marchand, L, Bapat, B, Thibodeau, SN, Lindor, NM, McGuckin, MA and Young, JP (2010) Lynch syndrome-associated breast cancers: Clinicopathologic characteristics of a case series from the colon cancer family registry. Clinical Cancer Research, 16 7: 2214-2224. doi:10.1158/1078-0432.CCR-09-3058

  • Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010) DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 3: 420-433. doi:10.1016/j.ajhg.2010.02.008

  • Arnold, Jeremy M., Choong, David Y. H., Thompson, Ella R., kConFab, Waddell, Nic, Lindeman, Geoffrey J., Visvader, Jane E., Campbell, Ian G., Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010) Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors. Breast Cancer Research And Treatment, 119 2: 491-496. doi:10.1007/s10549-008-0269-x

  • Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010) HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 4: R46-1-R46-11. doi:10.1186/bcr2603

  • Cummings, Margaret C., Da Silva, Leonard, Papadimos, David J. and Lakhani, Sunil R. (2009) Fibroadenoma and intraduct papilloma--a common pathogenesis?. Virchows Archiv, 455 3: 271-275. doi:10.1007/s00428-009-0817-8

  • Richmond-Sinclair, N.M., Lee, E., Cummings, M.C., Williamson, R., Muller, H.K., Green, A.C., Hayward, N.K. and Whiteman, D.C. (2008) Histologic and epidemiologic correlates of P-MAPK, Brn-2, pRb, p53 and p16 immunostaining in cutaneous melanomas. Melanoma research, 18 5: 336-345. doi:10.1097/CMR.0b013e32830d8329

  • Walsh, M. D., Cummings, M. C., Buchanan, D. D., Dambacher, W. M., Arnold, S., McKeone, D., Byrnes, R., Barker, M. A., Leggett, B. A., Gattas, M., Jass, J. R., Spurdle, A. B., Young, J. and Obermair, A. (2008) Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive Lynch Syndrome patients. Clinical Cancer Research, 14 6: 1692-1700. doi:10.1158/1078-0432.CCR-07-1849

  • Houston, AM, Michael-Robinson, JM, Walsh, MD, Cummings, MC, Ryan, AE, Lincoln, D, Pandeya, N, Jass, JR, Radford-Smith, GL and O'Connell, J (2008) The "Fas counterattack" is not an active mode of tumor immune evasion in colorectal cancer with high-level microsatellite instability. Human Pathology, 39 2: 243-250. doi:10.1016/j.humpath.2007.06.010

  • Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., Struewing, Jeffery P., Morrison, Jonathan, Field, Helen, Luben, Robert, Wareham, Nicholas, Ahmed, Shahana, Healey, Catherine S., Bowman, Richard, SEARCH collaborators, Meyer, Kerstin B., Haiman, Christopher A., Kolonel, Laurence K., Henderson, Brian E., Marchand, Loic Le, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Odefrey, Fabrice, Shen, Chen-Yang, Wu, Pei-Ei, Wang, Hui-Chun, Eccles Diana, Evans, D. Gareth, Peto, Julian, Fletcher, Olivia, Johnson, Nichola, Seal, Sheila, Stratton, Michael R., Rahman, Nazneen, Chenevix-Trench, Georgia, Bojesen, Stig E., Nordestgaard, Børge G., Axelsson, Christen K., Garcia-Closas, Montserrat, Brinton, Louise, Chanock, Stephen, Lissowska, Jolanta, Peplonska, Beata, Nevanlinna, Heli, Fagerholm, Rainer, Eerola, Hannaleena, Kang, Daehee, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Hunter, David J., Hankinson, Susan E., Cox, David G., Hall, Per, Wedren, Sara, Liu, Jianjun, Low, Yen-Ling, Bogdanova, Natalia, Schurmann, Peter, Dork, Thilo, Tollenaar, Rob A. E. M., Jacobi, Catharina E., Devilee, Peter, Klijn, Jan G. M., Sigurdson, Alice J., Doody, Michele M., Alexander, Bruce H., Zhang, Jinghui, Cox, Angela, Brock, Ian W., MacPherson, Gordon, Reed, Malcolm W. R., Couch, Fergus J., Goode, Ellen L., Olson, Janet E., Meijers-Heijboer, Hanne, van den Ouweland, Ans, Uitterlinden, Andre´, Rivadeneira, Fernando, Milne, Roger L., Ribas, Gloria, Gonzalez-Neira, Anna, Benitez, Javier, Hopper, John L., McCredie, Margaret, Southey, Melissa, Giles, Graham G., Schroen, Chris, Justenhoven, Christina, kConFab, AOCS Management Group, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Hartikainen, Jaana, Day, Nicholas E., Cox, David R., Ponder, Bruce A. J., Spurdle, Amanda B., Beesley, Jonathan, Brown, Melissa, Cummings, Margaret, Lakhani, Sunil, Armes, Jane and Ward, Robyn (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature, 447 7148: 1087-1093. doi:10.1038/nature05887

  • Herath, Nirmitha I., Spanevello, Mark D., Sabesan, Sabe, Newton, Tanya, Cummings, Margaret, Duffy, Shannon, Lincoln, Douglas, Boyle, Glen, Parsons, Peter G. and Boyd, Andrew W. (2006) Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival. BMC Cancer, 6 144: . doi:10.1186/1471-2407-6-144

  • Chenevix-Trench, Georgia, Healey, Sue, Lakhani, Sunil, Waring, Paul, Cummings, Margaret, Brinkworth, Ross, Deffenbaugh, Amie M., Burbidge, Lynn Anne, Pruss, Dmitry, Judkins, Thad, Scholl, Tom, Bekessy, Anna, Marsh, Anna, Lovelock, Paul, Wong, Ming, Tesoriero, Andrea, Renard, Helene, Southey, Melissa, Hopper, John L., Yannoukakos, Koulis, Brown, Melissa, kConFab Investigators, Easton, Douglas, Tavtigian, Sean V., Goldgar, David and Spurdle, Amanda B. (2006) Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variance of Unknown Clinical Significance. Cancer Research, 66 4: 2019-2027. doi:10.1158/0008-5472.CAN-05-3546

  • Bilous, Michael, Morey, Adrienne, Armes, Jane, Cummings, Margaret and Francis, Glenn (2006) Chromogenic in situ hybridisation testing for HER2 gene amplification in breast cancer produces highly reproducible results concordant with fluorescence in situ hybridisation and immunohistochemistry. Pathology, 38 2: 120-124. doi:10.1080/00313020600561518

  • Newton, Tanya R., Parsons, Peter G., Lincoln, Douglas J., Cummings, Margaret C., Wyld, David K., Webb, Penelope M., Green, Adele C. and Boyle, Glen M. (2006) Expression profiling correlates with treatment response in women with advanced serous epithelial ovarian cancer. International Journal of Cancer, 119 4: 875-883. doi:10.1002/ijc.21823

  • Farshid, G, Balleine, RL, Cummings, M, Waring, P and kConFab Grp (2006) Morphology of breast cancer as a means of triage of patients for BRCA1 genetic testing. American Journal of Surgical Pathology, 30 11: 1357-1366. doi:10.1097/01.pas.0000213273.22844.1a

  • Arnold, J. M., Huggard, P. R., Cummings, M., Ramm, G. A. and Chenevix-Trench, G. (2005) Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma. British Journal of Cancer, 92 11: 2024-2031. doi:10.1038/sj.bjc.6602596

  • Webb, PM, Cummings, MC, Bain, CJ and Furnival, CM (2004) Changes in survival after breast cancer: improvements in diagnosis or treatment?. Breast, 13 1: 7-14. doi:10.1016/S0960-9776(03)00129-2

  • Michael-Robinson, Julie M., Pandeya, Nirmala, Cummings, Margaret C., Walsh, Michael D., Young, Joanne P., Leggett, Barbara A., Purdie, David M., Jass, Jeremy R. and Radford-Smith, Graham L. (2003) Fas ligand and tumour counter-attack in colorectal cancer stratified according to microsatellite instability status. Journal of Pathology, 201 1: 46-54. doi:10.1002/path.1406

  • Cummings, M. C. (2003) Occult metastases in breast cancer. Cancer Forum, 27 2: 95-97.

  • Bilous, M., Ades, C., Armes, J., Bishop, J., Brown, R., Cooke, B., Cummings, M., Farshid, G., Field, A., Morey, A., McKenzie, P., Raymond, W., Robbins, P. and Tan, L. (2003) Predicting the HER2 status of breast cancer from basic histopathology data: an analysis of 1500 breast cancers as part of the HER2000 International Study. Breast, 12 2: 92-98. doi:10.1016/S0960-9776(02)00273-4

  • Cummings, M. C., Walsh, M. D., Hohn, B. G, Bennett, I. C., Wright, R. G. and McGuckin, M. A. (2002) Occult Axillary Lymph Node Metastases in Breast Cancer Do Matter: Results of 10-Year Survival Analysis. American Journal of Surgical Pathology, 26 10: 1286-1295. doi:10.1097/01.PAS.0000027303.89469.E2

  • Whiteman, David C., Zhou, Xiao-Ping, Cummings, Margaret C., Pavey, Sandra, Hayward, Nicholas K. and Eng, Charis (2002) Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. International Journal of Cancer, 99 1: 63-67. doi:10.1002/ijc.10294

  • Chenevix-Trench, Georgia, Spurdle, Amanda B., Gatei, Magtouf, Kelly, Helena, Marsh, Anna, Chen, Xiaoqing, Donn, Karen, Cummings, Margaret C., Nyholt, Dale, Jenkins, Mark A., Scott, Clare, Pupo, Gulietta M., Dork, Thilo, Bendix, Regina, Kirk, Judy, Tucker, Katherine, McCredie, Margaret R. E., Hopper, John L., Sambrook, Joseph, Mann, Graham J. and Khanna, Kum Kum (2002) Dominant negative ATM mutations in breast cancer families. Journal of the National Cancer Institute, 94 3: 205-215. doi:10.1093/jnci/94.3.205

  • Pavey, S. J., Cummings, M. C., Whiteman, D. C., Castellano, M., Walsh, M. D., Gabrielli, B. G., Green, A. and Hayward, N. K. (2002) Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Research, 12 6: 539-547. doi:10.1097/01.cmr.0000043154.28051.9f

  • Bilous, Michael, Ades, Colin, Armes, Jane, Bell, Richard, Brown, Robert, Cook, Bridget, Cummings, Margaret C., Field, Andrew, Llewellyn, Huw, McKenzie, Paul, Raymond, Wendy, Robbins, Peter and Tan, Lisa (2001) HER2 testing recommendations in Australia. Pathology, 33 4: 425-427. doi:10.1080/00313020120083133

  • Arnold, J. M., Cummings, M., Purdie, D. and Chenevix-Trench, G. (2001) Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. British Journal of Cancer, 85 9: 1351-1358. doi:10.1054/bjoc.2001.2075

  • Bellomo, D., Headrick, J. P., Silins, G. U., Paterson, C. A., Thomas, P. S., Gartside, M., Mould, A., Cahill, M. M., Tonks, I. D., Grimmond, S. M., Wells, C. A., Little, M. H., Cummings, M. C., Hayward, N. K. and Kay, G. F. (2000) Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circulation Research, 86 2: E29-E35.

  • Boonchai, Waranya, Walsh, Michael, Cummings, Margaret and Chenevix-Trench, Georgia (2000) Expression of p53 in arsenic-related and sporadic basal cell carcinoma. Archives of Dermatology, 136 2: 195-198. doi:10.1001/archderm.136.2.195

  • Aubele, M. M., Cummings, M. C., Mattis, A. E., Zitzelsberger, H. F., Walch, A. K., Kremer, M., Hofler, H. and Werner, M (2000) Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer. Diagnostic Molecular Pathology, 9 1: 14-19. doi:10.1097/00019606-200003000-00003

  • Boonchai, W., Walsh, M., Cummings, M. C. and Chenevix-Trench, G. (2000) Expression of b-catenin, a key mediator of the wnt signaling pathway, in basal cell carcinoma. Archives of Dermatology, 136 7: 937-938. doi:10.1001/archderm.136.7.937

  • Aubele, M., Cummings, M. C., Walch, A. K., Zitzelsberger, H., Nahrig, J., Hofler, H. and Werner, M. (2000) Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma. Analytical Cellular Pathology, 20 1: 17-24.

  • Cummings, M. C., Aubele, M., Mattis, A., Purdie, D., Hutzler, P., Hofler, H. and Werner, M. (2000) Increasing chromosome 1 copy number parallels histological progression in breast carcinogenesis. British Journal of Cancer, 82 6: 1204-1210. doi:10.1054/bjoc.1999.1064

  • Werner, M., Mattis, A., Aubele, M., Cummings, M. C., Zitzelsberger, H., Hutzler, P. and Hofler, H. (1999) 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast.. Virchows Archiv, 435 5: 469-472. doi:10.1007/s004280050429

  • Wright, Kim, Wilson, Peter, Morland, Sarah, Campbell, Ian, Walsh, Michael, Hurst, Terry G., Ward, Bruce G., Cummings, Margaret C. and Chenevix-Trench, Georgia (1999) Beta-catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumour. International Journal of Cancer, 82 5: 625-629. doi:10.1002/(SICI)1097-0215(19990827)82:5

  • Jass, J. R., Biden, K. G., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Metlzer, S. J., Wright, C., Searle, J., Young, J. and Leggett, B. A. (1999) Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology, 52 6: 455-460. doi:10.1136/jcp.52.6.455

  • Biden, Kelli G., Simms, Lisa A., Cummings, Margaret, Buttenshaw, Ron, Schoch, Estelle, Searle, Jeffrey, Gobe, Glenda, Jass, Jeremy R., Meltzer, Stephen J., Leggett, Barbara A. and Young, Joanne (1999) Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene, 18 5: 1245-1249. doi:10.1038/sj.onc.1202413

  • Walsh, M. D., Luckie, S. M., Cummings, M. C., Antalis, T. M. and McGuckin, M. A. (1999) Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro. Breast Cancer Research & Treatment, 58 3: 253-264. doi:10.1023/A:1006345301364

  • Shield, P. W., Nolan, G., Phillips, G. E. and Cummings, M. C. (1999) Improving cervical cytology screening in a remote, high risk population.. Medical Journal of Australia, 170 6: 255-258.

Conference Publication

  • Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. In: 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, (215-215). June 28th–July 1st, 2014. doi:10.1007/s10585-015-9708-3

  • Jass, J. R., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Meltzer, S. J., Wright, C., Searle, J., Young, J. P. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes. In: 11th Lorne Cancer Conference, Lorne, Victoria, Australia, (501). 11th -14th February, 1999.

  • Wright, K., Walsh, M. D., Cummings, M. C. and Chenevix-Trench, G. (1999). The E-cadherin-catenin system in ovarian cancer. In: Biochim Biophys Acta: Abstracts of the 11th Lorne Cancer Conference. 11th Lorne Cancer Conference, Lorne, Victoria, Australia, (721-721). 11th - 14th February, 1999.

  • Karamatic, R., Donnan, K. D., Cummings, M. C., Winterford, C. M., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). The effect of human bile and bile acids on duodenal epithelial cells. In: Inflammatory Bowel Disease incorporating Jaundice in Paradise. The Gastroenterological Society of Queensland, Coolum, Queensland, (1-1). 12th - 14th June, 1999.

Grants (Administered at UQ)