Journal Article: Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds
Powell, Lydia C., Cullen, Jason K., Boyle, Glen M., De Ridder, Tom, Yap, Pei-Yi, Xue, Wenya, Pierce, Carly J., Pritchard, Manon F., Menzies, Georgina E., Abdulkarim, Muthanna, Adams, Jennifer Y M, Stokniene, Joana, Francis, Lewis W., Gumbleton, Mark, Johns, Jenny, Hill, Katja E., Jones, Adam V., Parsons, Peter G., Reddell, Paul and Thomas, David W. (2022). Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds. Science translational medicine, 14 (662) abn3758, 1-18. doi: 10.1126/scitranslmed.abn3758
Journal Article: Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma)
Chianese, Giuseppina, Amin, Hawraz Ibrahim M., Maioli, Chiara, Reddell, Paul, Parsons, Peter, Cullen, Jason, Johns, Jenny, Handoko, Herlina, Boyle, Glen, Appendino, Giovanni, Taglialatela-Scafati, Orazio and Gaeta, Simone (2022). Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma). Journal of Natural Products, 85 (8), 1959-1966. doi: 10.1021/acs.jnatprod.2c00226
Journal Article: Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes
Cullen, Jason K., Boyle, Glen M., Yap, Pei-Yi, Elmlinger, Stefan, Simmons, Jacinta L., Broit, Natasa, Johns, Jenny, Ferguson, Blake, Maslovskaya, Lidia A., Savchenko, Andrei I., Mirzayans, Paul Malek, Porzelle, Achim, Bernhardt, Paul V., Gordon, Victoria A., Reddell, Paul W., Pagani, Alberto, Appendino, Giovanni, Parsons, Peter G. and Williams, Craig M. (2021). Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes. Scientific Reports, 11 (1) 207, 207. doi: 10.1038/s41598-020-80397-9
Linking Chemical Synthesis with Protein Discovery to Reveal Key Biological Pathways
(2012–2014) ARC Discovery Projects
Spider toxins as potential drug leads in breast cancer
(2011–2012) National Breast Cancer Foundation Novel Concept Award
Spheroid cell growth in melanocytic development and differentiation
(2009–2010) Cancer Council Queensland
The Antitumor Activity of a Novel Diterpene Ester
(2014) Doctor Philosophy
STUDIES OF SEROUS EPITHELIAL OVARIAN CANCER DEVELOPMENT: GENE EXPRESSION PATTERNS AND AETIOLOGICAL FACTORS
(2007) Doctor Philosophy
FACTORS ASSOCIATED WITH TREATMENT RESPONSE AND SURVIVAL AMONG WOMEN WITH LATE-STAGE OVARIAN CANCER
(2006) Doctor Philosophy
BRN2 in melanocytic cell development, differentiation and transformation
Cook, Anthony L., Boyle, Glen M., Leonard, J. Helen, Parsons, Peter G. and Sturm, Richard A. (2006). BRN2 in melanocytic cell development, differentiation and transformation. From Melanocytes to Melanoma: The Progression to Malignancy. (pp. 149-168) edited by V. J. Hearing and A. P. L. Leong. New Jersey: Humana Press. doi: 10.1007/978-1-59259-994-3_8
Powell, Lydia C., Cullen, Jason K., Boyle, Glen M., De Ridder, Tom, Yap, Pei-Yi, Xue, Wenya, Pierce, Carly J., Pritchard, Manon F., Menzies, Georgina E., Abdulkarim, Muthanna, Adams, Jennifer Y M, Stokniene, Joana, Francis, Lewis W., Gumbleton, Mark, Johns, Jenny, Hill, Katja E., Jones, Adam V., Parsons, Peter G., Reddell, Paul and Thomas, David W. (2022). Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds. Science translational medicine, 14 (662) abn3758, 1-18. doi: 10.1126/scitranslmed.abn3758
Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma)
Chianese, Giuseppina, Amin, Hawraz Ibrahim M., Maioli, Chiara, Reddell, Paul, Parsons, Peter, Cullen, Jason, Johns, Jenny, Handoko, Herlina, Boyle, Glen, Appendino, Giovanni, Taglialatela-Scafati, Orazio and Gaeta, Simone (2022). Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma). Journal of Natural Products, 85 (8), 1959-1966. doi: 10.1021/acs.jnatprod.2c00226
Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes
Cullen, Jason K., Boyle, Glen M., Yap, Pei-Yi, Elmlinger, Stefan, Simmons, Jacinta L., Broit, Natasa, Johns, Jenny, Ferguson, Blake, Maslovskaya, Lidia A., Savchenko, Andrei I., Mirzayans, Paul Malek, Porzelle, Achim, Bernhardt, Paul V., Gordon, Victoria A., Reddell, Paul W., Pagani, Alberto, Appendino, Giovanni, Parsons, Peter G. and Williams, Craig M. (2021). Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes. Scientific Reports, 11 (1) 207, 207. doi: 10.1038/s41598-020-80397-9
Topical treatments for skin cancer
Cullen, Jason K., Simmons, Jacinta L., Parsons, Peter G. and Boyle, Glen M. (2020). Topical treatments for skin cancer. Advanced Drug Delivery Reviews, 153, 54-64. doi: 10.1016/j.addr.2019.11.002
Barnett, Catherine M. E., Broit, Natasa, Yap, Pei-Yi, Cullen, Jason K., Parsons, Peter G., Panizza, Benedict J. and Boyle, Glen M. (2018). Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate. Investigational New Drugs, 37 (1), 1-8. doi: 10.1007/s10637-018-0604-y
The first plant 5,6-secosteroid from the Australian arid zone species Frankenia foliosa
Tan, Yuen P. , Savchenko, Andrei I. , Broit, Natasa , Boyle, Glen M. , Parsons, Peter G. and Williams, Craig M. (2017). The first plant 5,6-secosteroid from the Australian arid zone species Frankenia foliosa. European Journal of Organic Chemistry, 2017 (11), 1498-1501. doi: 10.1002/ejoc.201700035
Krainz, Tanja, Chow, Sharon, Korica, Natasa, Bernhardt, Paul V., Boyle, Glen M., Parsons, Peter G., Davies, Huw M. L. and Williams, Craig M. (2015). Rhodium-Catalyzed [4+3] Cycloaddition to Furans: Direct Access to Functionalized Bicyclo[5.3.0]decane Derivatives. European Journal of Organic Chemistry, 2016 (1), 41-44. doi: 10.1002/ejoc.201501271
Adams, Ryan A., D'Souza, Marjorie M. A., Pierce, Carly J., Korica, Natasa, Wallwork, Ben, Parsons, Peter G., Panizza, Benedict and Boyle, Glen M. (2015). Ectopic expression of Protein kinase C-beta sensitizes head and neck squamous cell carcinoma to diterpene esters. Anticancer Research, 35 (3), 1291-1296.
Maslovskaya, Lidiya A., Savchenko, Andrei I., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). Unprecedented 1,14-seco-Crotofolanes from Croton insularis: oxidative cleavage of crotofolin C by a putative homo-Baeyer–Villiger rearrangement. Chemistry: A European Journal, 20 (44), 14226-14230. doi: 10.1002/chem.201404250
Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond. Angewandte Chemie - International Edition, 53 (27), 7006-7009. doi: 10.1002/anie.201310923
The risk of Barrett's esophagus associated with abdominal obesity in males and females
Kendall, Bradley J., Macdonald, Graeme A., Hayward, Nicholas K., Prins, Johannes B., O'Brien, Suzanne, Whiteman, David C., Study of Digestive Health, Green. Adele C., Parsons, Peter G., Pavey, Sandra J., Purdie, David M. and Webb, Penelope M. (2013). The risk of Barrett's esophagus associated with abdominal obesity in males and females. International Journal of Cancer, 132 (9), 2192-2199. doi: 10.1002/ijc.27887
Dong, Ying, Stephens, Carson, Walpole, Carina, Swedberg, Joakim E., Boyle, Glen M., Parsons, Peter G., McGuckin, Michael A., Harris, Jonathan M. and Clements, Judith A. (2013). Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment. PLoS One, 8 (2) e57056, e57056.1-e57056.12. doi: 10.1371/journal.pone.0057056
Steroidal saponins from the roots of Smilax sp.: Structure and bioactivity
Challinor, Victoria L., Parsons, Peter G., Chap, Sonet, White, Eve F., Blanchfield, Joanne T., Lehmann, Reginald P. and De Voss, James J. (2012). Steroidal saponins from the roots of Smilax sp.: Structure and bioactivity. Steroids, 77 (5), 504-511. doi: 10.1016/j.steroids.2012.01.009
Micallef, Leanne S., Loughrey, Bradley T., Healy, Peter C., Parsons, Peter G. and Williams, Michael L. (2010). Synthesis, spectroscopic characterization, and cytotoxic evaluation of pentasubstituted ruthenocenyl esters. Organometallics, 29 (23), 6237-6244. doi: 10.1021/om100645y
Mason, Sharon A., Cozzi, Sarah-Jane, Pierce, Carly J., Pavey, Sandra J., Parsons, Peter G. and Boyle, Glen M. (2010). The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells. Investigational New Drugs, 28 (5), 575-586. doi: 10.1007/s10637-009-9292-y
Grange, RL, Gallen, MJ, Schill, H, Johns, JP, Dong, L, Parsons, PG, Reddell, PW, Gordon, VA, Bernhardt, PV and Williams, CM (2010). [4+2] Cycloaddition reactions between 1,8-disubstituted cyclooctatetraenes and diazo dienophiles: Stereoelectronic effects, anticancer properties and application to the synthesis of 7,8-substituted bicyclo [4.2.0] octa-2,4-dienes. Chemistry - A European Journal, 16 (29), 8894-8903. doi: 10.1002/chem.200903454
Healy, Peter C., Loughrey, Bradley T., Williams, Michael L. and Parsons, Peter G. (2010). Synthesis, structure and cytotoxicity studies of four-coordinate bis (cis–bis(diphenylphosphino)ethene) gold(I) complexes, [Au(dppey)2]X. Journal of Inorganic Biochemistry, 104 (6), 625-631. doi: 10.1016/j.jinorgbio.2010.02.003
Dong, Ying, Tan, Olivia L., Loessner, Daniela, Stephens, Carson, Walpole, Carina, Boyle, Glen M., Parsons, Peter G. and Clements, Judith A. (2010). Kallikrein-related peptidase 7 promotes multicellular aggregation via the α5β1 integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma. Cancer Research, 70 (7), 2624-2633. doi: 10.1158/0008-5472.CAN-09-3415
Characterization of the melanoma miRNAome by deep sequencing
Stark, Mitchell S., Tyagi, Sonika, Nancarrow, Derek J., Boyle, Glen M., Cook, Anthony L., Whiteman, David C., Parsons, Peter G., Schmidt, Christopher, Sturm, Richard A. and Hayward, Nicholas K. (2010). Characterization of the melanoma miRNAome by deep sequencing. PLoS One, 5 (3) e9685, e9685-1-e9685-9. doi: 10.1371/journal.pone.0009685
Solares, C. Arturo, Boyle, Glen M., Brown, Ian, Parsons, Peter G. and Panizza, Benedict (2010). Reduced alpha B-crystallin staining in perineural invasion of head and neck cutaneous squamous cell carcinoma. Otolaryngology, 142 (3 Supp. 1), S15-S19. doi: 10.1016/j.otohns.2009.12.001
Loughrey, Bradley T., Williams, Michael L., Carruthers, Thomas J., Parsons, Peter G. and Healy, Peter C. (2010). Synthesis, structure, and selective cytotoxicity of organometallic Cp*RuII O-alkyl-N-phenylcarbamate sandwich complexes. Australian Journal of Chemistry, 63 (2), 245-251. doi: 10.1071/CH09420
Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer
Merritt, Melissa A., Parsons, Peter G., Newton, Tanya R., Martyn, Adam C., Webb, Penlope M., Green, Adele C., Papadimos, David J. and Boyle, Glen M. (2009). Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer. BMC Cancer, 9 (1) 1471, 378.1-378.13. doi: 10.1186/1471-2407-9-378
Dong, Lin, Schill, Heiko, Grange, Rebecca L., Porzelle, Achim, Johns, Jenny P., Parsons, Peter G., Gordon, Victoria A., Reddell, Paul W. and Williams, Craig M. (2009). Anticancer agents from the Australian tropical rainforest: Spiroacetals EBC-23, 24, 25, 72, 73, 75 and 76. Chemistry: A European Journal, 15 (42), 11307-11318. doi: 10.1002/chem.200901525
Loughrey, Bradley T., Williams, Michael L., Healy, Peter C., Innocenti, Alessio, Vullo, Daniela, Supuran, Claudiu T., Parsons, Peter G. and Poulsen, Sally-Ann (2009). Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase. Journal of Biological Inorganic Chemistry, 14 (6), 935-945. doi: 10.1007/s00775-009-0506-8
H-Cadherin expression reduces invasion of malignant melanoma
Kuphal, Silke, Martyn, Adam C., Pedley, Julie, Crowther, Lisa M., Bonazzi, Vanessa F., Parsons, Peter G., Bosserhoff, Anja K., Hayward, Nicholas K. and Boyle, Glen M. (2009). H-Cadherin expression reduces invasion of malignant melanoma. Pigment Cell and Melanoma Research, 22 (3), 296-306. doi: 10.1111/j.1755-148X.2009.00568.x
Regioselective acylation of 3-O-angeloylingenol by Candida antarctica Lipase B
R.W. Teng, D. McManus, J. Aylward, S. Ogbourne, J. Johns, P. Parsons and A. Bacic (2009). Regioselective acylation of 3-O-angeloylingenol by Candida antarctica Lipase B. Fitoterapia, 80 (4), 233-236. doi: 10.1016/j.fitote.2009.02.001
PPARγ agonists attenuate proliferation and modulate Wnt/β-catenin signalling in melanoma cells
Smith, Aaron G., Beaumont, Kimberley A., Smit, Darren J., Thurber, Amy E., Cook, Anthony L., Boyle, Glen M., Parsons, Peter G., Sturm, Richard A. and Muscat, George E. O. (2009). PPARγ agonists attenuate proliferation and modulate Wnt/β-catenin signalling in melanoma cells. The International Journal of Biochemistry & Cell Biology, 41 (4), 844-852. doi: 10.1016/j.biocel.2008.08.037
C. Arturo Solares, Ian Brown, Glen M. Boyle, Peter G. Parsons and Benedict Panizza (2009). Neural cell adhesion molecule expression: No correlation with perineural invasion in cutaneous squamous cell carcinoma of the head and neck. Head & Neck, 31 (6), 802-806. doi: 10.1002/hed.21037
Structure and absolute stereochemistry of the anticancer agent EBC-23 from the Australian rainforest
Dong, Lin, Gordon, Victoria A., Grange, Rebecca L., Johns, Jenny, Parsons, Peter G., Porzelle, Achim, Reddell, Paul, Schill, Heiko and Williams, Craig M. (2008). Structure and absolute stereochemistry of the anticancer agent EBC-23 from the Australian rainforest. Journal of American Chemical Society, 130 (46), 15262-15263. doi: 10.1021/ja807133p
Boyle, Glen M., Pedley, Julie, Martyn, Adam C., Banducci, Kelly J., Strutton, Geoffrey M., Brown, David A., Breit, Samuel N. and Parsons, Peter G. (2008). Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity. The Journal of Investigative Dermatology, 129 (2), 383-391. doi: 10.1038/jid.2008.270
Conway-Campbell, B., Wooh, J., Brooks, A., Gordon, D, Brown, R. J., Lichanska, A. M., Chin, H., Barton, C., Boyle, G., Parsons, P., Jans, D. A. and Waters, M. J. (2007). Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis. Proceedings of The National Academy of Sciences of The United States of America, 104 (33), 13331-13336. doi: 10.1073/pnas.0600181104
Proceedings of the First International Conference on PEP005
Ogbourne, S. M., Hampson, P., Lord, J. M., Parsons, P., De Witte, P. A. and Suhrbier, A. (2007). Proceedings of the First International Conference on PEP005. Anti-Cancer Drugs, 18 (3), 357-362. doi: 10.1097/CAD.0b013e3280149ec5
Surfactant protein expression in human skin: Evidence and implications
Mo, Y.-K., Kankavi, O., Masci, P. P., Mellick, G. D., Whitehouse, M. W., Boyle, G. M., Parsons, P. G., Roberts, M. S. and Cross, S. E. (2007). Surfactant protein expression in human skin: Evidence and implications. Journal of Investigative Dermatology, 127 (2), 381-386. doi: 10.1038/sj.jid.5700561
Davis, Rohan A., Pierens, Gregory K. and Parsons, Peter G. (2007). Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide. Magnetic Resonance in Chemistry, 45 (5), 442-445. doi: 10.1002/mrc.1984
Young, Neville, Hahn, Christopher N., Poh, Alisa, Dong, Carolyn, Wilhelm, Dagmar, Olsson, Jane, Muscat, George E. O., Parsons, Peter, Gamble, Jennifer R. and Koopman, Peter (2006). Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development. Journal of The National Cancer Institute, 98 (15), 1060-1067. doi: 10.1093/jnci/djj299
van der Pols, Jolieke C., Xu, Chunxia, Boyle, Glen M., Parsons, Peter G., Whiteman, David C. and Green, Adele C. (2006). Expression of p53 tumor suppressor protein in sun-exposed skin and associations with sunscreen use and time spent outdoors: A community-based study. American Journal of Epidemiology, 163 (11), 982-988. doi: 10.1093/aje/kwj137
Kahnberg, P. C., Lucke, A., Glenn, M. P., Boyle, G. M., Tyndall, J. D., Parsons, P. G. and Fairlie, D. P. (2006). Design, Synthesis, Potency and Cytoselectivity of Anticancer Agents Derived by Parallel Synthesis from alpha-Aminosuberic Acid. Journal of Medicinal Chemistry, 49 (26), 7611-7622. doi: 10.1021/jm050214x
Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein
Widyarini, Sitarina, Allanson, Munif, Gallagher, Nerida L., Pedley, Julie, Boyle, Glen M., Parsons, Peter G., Whiteman, David C., Walker, Catherine and Reeve, Vivienne E. (2006). Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein. Journal of Investigative Dermatology, 126 (1), 198-204. doi: 10.1038/sj.jid.5700013
New Cysteine Derivatives with Antiproliferative Activity on Melanoma Cells
Lucke, A., Boyle, G. M., Parsons, P. G. and Fairlie, D. (2006). New Cysteine Derivatives with Antiproliferative Activity on Melanoma Cells. Medicinal Chemistry, 2 (2), 123-132. doi: 10.2174/157340606776056124
Histone deacetylase inhibitors and malignant melanoma
Boyle, Glen M., Martyn, Adam C. and Parsons, Peter G. (2005). Histone deacetylase inhibitors and malignant melanoma. Pigment Cell and Melanoma Research, 18 (3), 160-166. doi: 10.1111/j.1600-0749.2005.00228.x
Invasion and metastasis markers in cancers
Chin, David, Boyle, Glen M., Kane, Anthony J., Theile, David, Hayward, Nicholas K., Parsons, Peter G. and Coman, William B. (2005). Invasion and metastasis markers in cancers. British Journal of Plastic Surgery, 58 (4), 466-474. doi: 10.1016/j.bjps.2004.12.025
Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells
Newton, R. A., Smit, S. E., Barnes, C. C., Pedley, J., Parsons, P. G. and Sturm, R. A. (2005). Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells. Peptides, 26 (10), 1818-1824. doi: 10.1016/j.peptides.2004.11.031
van der Pols, J. C., Xu, C, X., Boyle, G. M., Parsons, P. G., Williams, G. M. and Green, A. C. (2005). Is expression of p53 protein in dorsal hand skin predictive of the seven year risk and site distribution of basal and squamous cell carcinomas of the skin?. Cancer Epidemiology Biomarkers & Prevention, 14 (11 (Part 2)), 2684S-2684S.
Microarray expression profiling in melanoma reveals a BRAF mutation signature
Pavey, Sandra, Johansson, Peter, Packer, Leisl, Taylor, Jennifer, Stark, Mitchell, Pollock, Pamela M., Walker, Graeme J., Boyle, Glen M., Harper, Ursula, Cozzi, Sarah-Jane, Hansen, Katherine, Yudt, Laura, Schmidt, Chris, Hersey, Peter, Ellem, Kay A. O., O'Rourke, Michael G. E., Parsons, Peter G., Meltzer, Paul, Ringnér, Markus and Hayward, Nicholas K. (2004). Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene, 23 (23), 4060-4067. doi: 10.1038/sj.onc.1207563
Van Gele, M, Boyle, GM, Cook, AL, Vandesompele, J, Boonefaes, T, Rottiers, P, Van Roy, N, De Paepe, A, Parsons, PG, Leonard, JH and Speleman, F (2004). Gene-expression profiling reveals distinct expression patterns for classic versus variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma. Oncogene, 23 (15), 2732-2742. doi: 10.1038/sj.onc.1207421
Leonard, J. Helen, Marks, Lisa H., Chen, Wei, Cook, Anthony L., Boyle, Glen M., Smit, Darren J., Brown, Darren L., Stow, Jennifer L., Parsons, Peter G. and Sturm, Richard A. (2003). Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: Pigmentation marker, ultrastructural and UV-survival studies. Pigment Cell Research, 16 (3), 198-207. doi: 10.1034/j.1600-0749.2003.00033.x
A rapid method for determining recent sunscreen use in field studies
Whiteman, DC, Brown, RM, Xu, CX, Paterson, CL, Miller, D and Parsons, PG (2003). A rapid method for determining recent sunscreen use in field studies. Journal of Photochemistry And Photobiology B-biology, 69 (1), 59-63. doi: 10.1016/S1011-1344(02)00409-8
Ablett, E, Whiteman, DC, Boyle, GM, Green, AC and Parsons, PG (2003). Induction of metallothionein in human skin by routine exposure to sunlight: Evidence for a systemic response and enhanced induction at certain body sites. Journal of Investigative Dermatology, 120 (2), 318-324. doi: 10.1046/j.1523-1747.2003.12025.x
Andrews, Kathy T., Walduck, Anna, Kelso, Mike J., Fairlie, David P., Saul, Allan and Parsons, Peter G. (2000). Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Anna Walduck, Mike J. Kelso, David P. Fairlie, Allan Saul, Peter G. Parsons. International Journal for Parasitology, 30 (6), 761-768. doi: 10.1016/S0020-7519(00)00043-6
Critical targets of protein kinase C in differentiation of tumour cells
Watters, Dianne J. and Parsons, Peter G. (1999). Critical targets of protein kinase C in differentiation of tumour cells. Biochemical Pharmacology, 58 (3), 383-388. doi: 10.1016/S0006-2952(99)00063-5
Qiu, L., Kelso, M., Hansen, C., West, M. L., Fairlie, D. and Parsons, P. (1999). Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.. British Journal of Cancer, 80 (8), 1252-1258. doi: 10.1038/sj.bjc.6690493
Green, A., Williams, G., Neale, R., Hart, V., Leslie, D., Parsons, P., Marks, G. C., Gaffney, P., Battistutta, D., Frost, C., Lang, C. and Russell, A. (1999). Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet, 354 (9180), 723-729. doi: 10.1016/S0140-6736(98)12168-2
Up-regulation of growth hormone receptor immunoreactivity in human melanoma
Lincoln, D.T., Sinowatz, F., Kolle, S., Takahashi, H., Parsons, P. and Waters, M. J. (1999). Up-regulation of growth hormone receptor immunoreactivity in human melanoma. Anticancer Research, 19 (3A), 1919-1932.
White, C. A., Thomson, S. A., Cooper, L., van Endert, P. M., Tampe, R., Coupar, B., Qiu, L., Parsons, P. G., Moss, D. J. and Khanna, R. (1998). Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells. International Journal of Cancer, 75 (4), 590-595. doi: 10.1002/(SICI)1097-0215(19980209)75:4<590::AID-IJC16>3.0.CO;2-D
Aoude, L., Ferguson, B., Gordon, V., Johns, J., Maslovskaya, L., Parsons, P., Pierce, C., Reddell, P., Savchenko, A. and Williams, C. (2008). Cell culture-based assays identify edible rainforest fruits with potential for chemoprevention of cancer. 4th Australian Health and Medical Research Congress, Brisbane, Australia, 16-21 November 2008. Sydney, Australia: AHMRC.
Rao, D. Visala, Boyle, Glen M., Parsons, Peter G., Watson, Kenneth and Jones, Graham L. (2003). Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes. International Conference on Functional Genomics of Ageing, Seville, Spain, 24-27 April 2003. Shannon, Ireland: Elsevier. doi: 10.1016/S0047-6374(02)00170-7
Linking Chemical Synthesis with Protein Discovery to Reveal Key Biological Pathways
(2012–2014) ARC Discovery Projects
Spider toxins as potential drug leads in breast cancer
(2011–2012) National Breast Cancer Foundation Novel Concept Award
Spheroid cell growth in melanocytic development and differentiation
(2009–2010) Cancer Council Queensland
Melanocytic spheroids as a model for melanoma development and metastasis
(2007–2008) Queensland Cancer Fund
(2006–2007) ARC Discovery Projects
(2003) University of Queensland Research Development Grants Scheme
The Antitumor Activity of a Novel Diterpene Ester
(2014) Doctor Philosophy — Principal Advisor
STUDIES OF SEROUS EPITHELIAL OVARIAN CANCER DEVELOPMENT: GENE EXPRESSION PATTERNS AND AETIOLOGICAL FACTORS
(2007) Doctor Philosophy — Principal Advisor
FACTORS ASSOCIATED WITH TREATMENT RESPONSE AND SURVIVAL AMONG WOMEN WITH LATE-STAGE OVARIAN CANCER
(2006) Doctor Philosophy — Principal Advisor
MECHANISMS OF HUMAN BRONCHIAL CARCINOGENESIS
(2006) Doctor Philosophy — Principal Advisor
MOLECULAR TARGETS OF ANTICANCER PKC ACTIVATORS IN THE TREATMENT OF MELANOMA
(2005) Doctor Philosophy — Principal Advisor
EVALUATION OF THE EFFICACY AND SAFETY OF SUNSCREENS
(2004) Doctor Philosophy — Principal Advisor
EFFICACY AND ACTION OF TOPIAL DITERPENES FROM EUPHORBIA REPLUS IN SKIN CANCER
(2003) Master Philosophy — Principal Advisor
Enhancing the efficacy of EBC-46 in the treatment of head and neck squamous cell carcinoma
(2018) Master Philosophy — Associate Advisor
Other advisors:
(2017) Master Philosophy — Associate Advisor
Other advisors:
The Efficacy and Mechanism of Action of EBC-46 in Head and Neck Squamous Cell Carcinoma
(2013) Master Philosophy — Associate Advisor
Other advisors:
The Role of MicroRNA in Head and Neck Cancer
(2013) Master Philosophy — Associate Advisor
Novel Prognostic markers in head and neck cancers
(2008) Doctor Philosophy — Associate Advisor
IMMUNOLOGICAL, VIROLOGICAL AND MOLECULAR BIOLOGICAL ANALYSIS OF NASOPHARYNGEAL CARCINOMA
(2005) Master Philosophy — Associate Advisor
THE TOXICOLOGY OF CYANO-HYDROXY-BUTENE AND ITS EFFECT ON ADENOCARCINOMA OF THE PANCREAS
(2003) Doctor Philosophy — Associate Advisor
MACROCYCLIC PSEUDOPEPTIDES AS MIMICS OF BIOACTIVE PROTEIN SURFACES
(2002) Doctor Philosophy — Associate Advisor
Other advisors: