Associate Professor John O'Sullivan

Academic Title-Associate Professor

UQ Centre for Clinical Research
Faculty of Medicine

Overview

After completing neurology training at the Royal Brisbane & Women’s Hospital, A/Prof O’Sullivan completed Fellowships in Movement Disorders at the Austin & Repatriation Medical Centre, Melbourne then the National Hospital for Neurology and Neurosurgery, and Middlesex Hospital in London, UK. He was awarded a doctorate in Medicine from Melbourne University in 2000 for studies into surgery for Parkinson’s disease. He returned to Royal Brisbane & Women's Hospital (RBWH) and set up the Movement Disorders Clinical Service including botulinum toxin and later Friedreich's ataxia clinics, and co-ordinating the Huntington's disease multidisciplinary clinic. Through these clinics he has established collaborations with local, interstate and international researchers in the fields of Parkinson's disease, movement disorders and neurodegenerative diseases. He is currently Associate Professor of Medicine at UQ Centre for Clinical Research, previously Royal Brisbane and UnitingCare Health Clinical Units in UQ School of Clinical Medicine. He is also Senior Reserch Fellow at Wesley Medical Research. A/Prof O'Sullivan is on the Board of the Clem Jones Centre for Ageing Dementia Research and is currently President of the Movement Disorders Society of Australia and New Zealand (MDSANZ), having previously served as Chair of the MDSANZ Clinical Trials and Research Group.

Research Interests

  • Non-motor features of Parkinson's disease
    This research involves studies into depression, anxiety and cognitive function in Parkinson's disease in collaboration with Dr Nadeeka Dissanayaka, Prof Gerard Byrne, Dr Nancy Pachana & Dr Rodney Marsh
  • Sleep in neurodegenerative diseases
    These studies in collaboration with Dr Susanna Mantovani, Dr Simon Smith, Dr Jane Nikles and Wesley Medical Research explore novel aspects involving sleep in Parkinson's, Huntington's and motor neurone diseases and Friedreich's ataxia
  • Exercise in Parkinson's disease
    In collaboration with Prof Sandy Brauer, Dr Robyn Lamont, Prof Jeff Coombes and Wesley Medical Research, studies exploring maintenance of exercise, gait and boxing in Parkinson's disease.
  • Novel compounds and clinical trials in neurodegenerative diseases
    Research involves novel compounds and repurposed drugs for treatment and disease-modification in Parkinson's and motor neurone diseases in collaboration with Dr Richard Gordon, A/Prof Trent Woodruff, A/Prof Rob Henderson, Prof Pam McCombe and Wesley Medical Research.

Qualifications

  • MD, University of Melbourne
  • MBBS, The University of Queensland

Publications

  • Gassner, Christoph, Brönnimann, Chantal, Merki, Yvonne, Mattle-Greminger, Maja P., Sigurdardottir, Sonja, Meyer, Eduardo, Engström, Charlotte, O'Sullivan, John D., Jung, Hans H. and Frey, Beat M. (2017) Stepwise partitioning of Xp21: a profiling method for XK deletions causative of the McLeod syndrome. Transfusion, 57 9: 2125-2135. doi:10.1111/trf.14172

  • Yang, J. H., McMahon, K., Copland, D., Byrne, G., Toft, A., Mithcell, L., O'Sullivan, J. and Dissanayaka, N. (2017). Altered attentional brain network in Parkinson's disease with mild cognitive impairment. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Dissanayaka, N., Hennessy, D., Au, T., Angwin, A., Yang, J. H., O'Sullivan, J. and Copland, D. (2017). EEG Markers for Emotional Inhibition in Parkinson's Disease. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

View all Publications

Supervision

View all Supervision

Publications

Journal Article

Conference Publication

  • Yang, J. H., McMahon, K., Copland, D., Byrne, G., Toft, A., Mithcell, L., O'Sullivan, J. and Dissanayaka, N. (2017). Altered attentional brain network in Parkinson's disease with mild cognitive impairment. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Dissanayaka, N., Hennessy, D., Au, T., Angwin, A., Yang, J. H., O'Sullivan, J. and Copland, D. (2017). EEG Markers for Emotional Inhibition in Parkinson's Disease. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Dissanayaka, N., Au, T., Angwin, A., O'Sullivan, J., Byrne, G., Silburn, P., Marsh, R., Mellick, G. and Copland, D. (2017). Electrophysiological markers for emotional and cognitive impairment in Parkinson's disease. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Dissanayaka, N., Pachana, N., O'Sullivan, J., Marsh, R., Silburn, P., White, E., Torbey, E., Pye, D., Mitchell, L., Yang, J. H., Au, T., Mellick, G., Copland, D., Toft, A. and Byrne, G. (2017). Improving Diagnosis and Treatment of Anxiety in Parkinson's Disease: Idata-Pd Study. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Toft, A., Yang, J., Byrne, G., O'Sullivan, J., Mitchell, L., Copland, D. and Dissanayaka, N. (2017). Investigating the association between anxiety and cognitive impairment in Parkinson's disease: A descriptive study. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Julia, J. H., McMahon, K., Copland, D., Byrne, G., Toft, A., Mithcell, L., O'Sullivan, J. and Dissanayaka, N. (2017). Understanding neural activation in semantic fluency in Parkinson's disease with mild cognitive impairment. In: Movement Disorders. 21st International Congress of Parkinson's Disease and Movement Disorders, Vancouver Canada, (). Jun 04-08, 2017.

  • Pachana, N. A., Dissanayaka, N. N., Jion, F. I., Harnett, P. and O'Sullivan, J. (2015). Mindfulness to combat anxiety in people with Parkinson's disease. In: *, *, (S31-S31). *.

  • Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. In: 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, (124-124). 23-27 August 2015. doi:10.1111/jnc.13188

  • Shaffer, J., Nguyen, G., Coulthard, A., Wong, A., O'Sullivan, J. and Reutens, D. (2015). Segmentation Test-Retest of Perfusion Computed Tomography-Obtained Blood-Brain Barrier in Prediction of Infarct Expansion Following Acute Ischaemic Stroke. In: Journal of Investigative Medicine. Southern Regional Meeting of the American-Federation-for-Medical-Research, New Orleans, LA, United States, (443-444). 26-28 February 2015. doi:10.1097/JIM.0000000000000146

  • Lehn, A. C., Airey, C. A., O'Sullivan, J. and Boyle, R. (2013). Deep brain stimulation for DYT3 dystonia: A case report. In: , , (S9-S10). .

  • Carter, Adrian, O'Sullivan, John, Dissanayaka, Nadeeka, Bartlett, Francesca, Hall, Wayne and Bell, Peter (2013). Drug-induced compulsive disorders: clinical, ethical and legal challenges. In: Special Issue: Abstracts of the Australasian Professional Society on Alcohol and other Drugs Conference. Australasian Professional Society on Alcohol and other Drugs Conference, Brisbane, QLD Australia, (6-6). 24-27 November 2013. doi:10.1111/dar.12077

  • Dissanayaka, N. N., Au, T., Angwin, A., Copland, D., O'Sullivan, J., Byrne, G. J., Marsh, R., Mellick, G. and Silburn, P. A. (2013). Identifying EEG markers associated with anxiety in Parkinson's disease: late positive potential. In: Abstracts of the Seventeenth International Congress of Parkinson's Disease and Movement Disorders. MDS 2013: 17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, NSW, Australia, (83-84). 16-20 June, 2013. doi:10.1002/mds.25605

  • Carter, Adrian, Bell, Peter, Diezel, Helene, Dissanayaka, Nadeeka, O'Sullivan, John and Hall, Wayne (2013). Patient perspectives on treatment-induced impulse control disorders. In: Special Issue: Abstracts of the Australasian Professional Society on Alcohol and other Drugs Conference. Australasian Professional Society on Alcohol and other Drugs Conference, Brisbane, QLD Australia, (7-8). 24-27 November 2013. doi:10.1111/dar.12077

  • Sheikh, N., Wong, A., O'Sullivan, J., Blum, S., Airey, C., Dionisio, S., Mitchell, K., Coulthard, A., Cloustan, J., Groundwater, A., Rajah, T., Jhamb, A. and Henderson, R. (2012). CT perfusion and bilateral paramedian thalamic stroke due to Artery of Percheron occlusion. In: Special Issue: Abstracts of STROKE 2012 CONFERENCE - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference. Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney, NSW, Australia, (56-57). 29-31 August 2012. doi:10.1111/j.1747-4930.2012.00907.x

  • Dissanayaka, Nadeeka, Au, Tiffany, Angwin, Anthony, Copland, David, O’Sullivan, John, Byrne, Gerard, Marsh, Rodney, Mellick, George and Silburn, Peter (2012). Neural correlates of emotional processing in Parkinson’s disease and the influence of affective disturbances. In: Conference Abstract: ACNS-2012 Australasian Cognitive Neuroscience Conference. 3rd Australasian Cognitive Neuroscience Conference (ACNS 2012 ), Brisbane, Australia, (). 29 November - 2 December 2012. doi:10.3389/conf.fnhum.2012.208.00140

  • Berkovic, S. F., Corbett, M. A., Schwake, M., Bahlo, M., Dibbens, L. M., Lin, M., Gandolfo, L., Vears, D., O'Sullivan, J., Robertson, T., Bayly, M. A., Gardner, A. E., Vlaar, A. M., Korenke, G. C., Bloem, B. R., de Coo, I. F., Verhagen, J. M. A, Lehesjoki, A. E., Saftig, P. and Gecz, J. (2011). A New Form of Progressive Myoclonus Epilepsy with Early Ataxia and Scoliosis Due to Mutation in the Golgi Protein Gosr2. In: Epilepsia. 29th International Epilepsy Congress, Rome Italy, (94-95). Aug 28-Sep 01, 2011.

  • Dissanayaka, N., Angwin, A., Copland, D., O’Sullivan, J., Byrne, G., Marsh, R., Mellick, G. and Silburn, P. (2011). Abnormal event related brain potentials generated while processing emotional information in anxious Parkinson’s disease patients. In: 20th RBWH Healthcare Symposium, Brisbane, Australia, (). 10-14 October 2011.

  • Dissanayaka, Nadeeka, Au, Tiffany, Angwin, Anthony, Copland, David, O’Sullivan, John, Byrne, Gerard, Marsh, Rodney, Mellick, George and Silburn, Peter (2011). Abnormal event related brain potentials generated while processing emotional information in anxious Parkinson’s disease patients. In: 2nd Australasian Cognitive Neuroscience Conference, Sydney, Australia, (). 9-12 December 2011.

  • Dissanayaka, Nadeeka N., O'Sullivan, John D., Silburn, Peter A. and Mellick, George D. (2011). Assessment methods and factors associated with depression in Parkinson's disease. In: 7th International Congress on Mental Dysfunction and other Non-Motor Features in Parkinsons Disease and Related Disorders, Barcelona, Spain, (208-210). 9-12 December 2010. doi:10.1016/j.jns.2011.06.031

  • Dissanayaka, N., O’Sullivan, J., Silburn, P. and Mellick, G. (2010). Factors associated with freezing of gait in Parkinson’s disease. In: 19th Annual RBWH Health Care Symposium, Brisbane, Australia, (). 11-15 October 2010.

  • Barwood, Caroline, Murdoch, Bruce, Whelan, Brooke-Mai, Lloyd, David, Riek, Stephan and O'Sullivan, John (2010). Repetitive Transcranial Magnetic Stimulation (rTMS) and sham modulation of language function in non-fluent aphasia 2 months post stimulation. In: Costanza Papagno, AoA2010: 48th Academy of Aphasia Proceedings, Athens, Greece, (233-234). 23-26 October, 2010. doi:10.1016/j.sbspro.2010.08.117

  • Dissanayaka, N. N., O’Sullivan, J. D., Silburn, P. A. and Mellick, G. D. (2010). Risk factors for depression in Parkinson’s disease. In: 7th International Congress on Mental Dysfunctions and Other Non-motor Features in Parkinson’s Disease and Related Disorders, Barcelona, Spain, (). 9-12 December 2010.

  • Dissanayaka, N. N. W., Sellbach, A., Matheson, S., Marsh, R., Silburn, P. A., O'Sullivan, J. D., Byrne, G. J. and Mellick, G. D. (2009). Assessing depression in Parkinson’s disease. In: 5th National Conference on Depression in Elderly., Sydney, Australia, (). 2009.

  • Dissanayaka, N., Sellbach, A., Matheson, S., O'Sullivan, J., Silburn, P. A., Marsh, R., Byrne, G. and Mellick, G. (2009). Risk factors for depression in Parkinson’s disease. In: 18th Annual RBWH Health Care Symposium, Brisbane, Australia, (). October 2009.

  • Dissanayaka, N. N., Sellbach, A., Matheson, S., Marsh, R., Silburn, P. A., O'Sullivan, J. D., Byrne, G. J. and Mellick, G. D. (2009). Risk factors for depression in Parkinson’s disease. In: Combined Abstracts of 2009 Australian Psychology Conferences. 1st Joint Conference of the APS Psychology and Ageing Interest Group, and the Royal Australian and New Zealand College of Psychiatrists Faculty of Psychiatry of Old Age, Gold Coast, Australia, (193-194). 12-14 November 2009.

  • Dissanayaka, N. N. W., Silburn, P. A., O’Sullivan, J. D. and Mellick, J. D. (2009). What contributes to depression in Parkinson’s disease?. In: Australian Society for Medical Research Queensland Postgraduate Student Conference, Brisbane, Australia, (). 26 May 2009.

  • Dissanayaka, N., Silburn, P., O’Sullivan, J. and Mellick, G. (2008). Is depression in Parkinson’s disease ‘organic’ or ‘reactive’. In: Australian Society for Medical Research Queensland Postgraduate Student Conference, Brisbane, Australia, (). 29 May 2008.

  • Dissanayaka, N., O’Sullivan, J., Silburn, P. and Mellick, G. (2008). Risk factors for depression in Parkinson’s disease. In: 6th International Congress on Mental Dysfunctions and Other Non-motor Features in Parkinson’s Disease, Dresden, Germany, (). 16-19 October 2008.

  • Yan, J., Greer, J. M., Cavanagh, H., Henderson, R., O'Sullivan, J., Read, S., Etherington, K. and McCombe, P. A. (2007). Increased population of activated T cells in patients after acute ischemic stroke. In: 37th Annual Scientific Meeting of the Australasian Society for Immunology, Sydney, Australia, (). 2-6 December 2007.

  • Dissanayaka, N., Selbach, A., Matheson, S., Marsh, R., Silburn, P. A., O'Sullivan, J. D., Byrne, G. J. and Mellick, G. D. (2006). Assessing risk factors for depression in Parkinson’s disease. In: Abstracts and proceedings from the 5th National Conference for Emerging Researchers in Ageing. 5th National Conference of Emerging Researchers in Aging, Sydney, Australia, (-64). 2006.

  • Pandian, J, Wong, A, Lincoln, D, Davis, J, Henderson, R, O'Sullivan, J and Read, S (2005). Circadian blood pressure variation after acute stroke. In: Journal of the Neurological Sciences. 18th World Congress of Neurology, Sydney Australia, (S428-S428). Nov 05-11, 2005.

  • Schoffer, KL and O'Sullivan, JD (2005). Development of a patient knowledge questionnaire for botulinum toxin use in movement disorders. In: Journal of the Neurological Sciences. 18th World Congress of Neurology, Sydney Australia, (S328-S329). Nov 05-11, 2005.

  • O'Sullivan, JD, Turner, K, Marks, L and Lees, AJ (2002). Controlled trial of speech therapy and intra-parotid botulinum toxin for the treatment of salivary drooling in Parkinson's disease. In: Movement Disorders. 7th International Congress of Parkinsons Disease and Movement Disorders, Miami Florida, (S94-S95). Nov 10-14, 2002.

  • Katzenschlager, R, Costa, D, Gerschlager, W, O'Sullivan, JD, Lees, AJ and Brown, P (2002). Dopamine transporter imaging with I-123-FP-CIT SPECT demonstrates marked presynaptic nigrostriatal dopaminergic deficit in orthostatic tremor. In: Movement Disorders. 7th International Congress of Parkinsons Disease and Movement Disorders, Miami Florida, (S346-S346). Nov 10-14, 2002.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Associate Advisor

Completed Supervision