The University of Queensland

Identification and isolation of synovial dendritic cells

Pettit, Allison R., Cavanagh, Lois, Boyce, Amanda, Padmanabha, Jagadish, Peng, Judy and Thomas, Ranjeny. (2007). Identification and isolation of synovial dendritic cells. Arthritis Research Methods and Protocols. (pp. 165-181) edited by Andrew P. Cope. Totowa, N.J., U.S.A.: Humana Press Inc.

Osteoprotegerin

Pettit, Allison R. and Gravallese, E. M. (2007). Osteoprotegerin. Contemporary Targeted Therapies in Rheumatology. (pp. 251-264) edited by Peter E. Lipsky and Josef S. Smolen. London, United Kingdom: Informa Healthcare.

Pathogenesis of focal bone loss in inflammatory arthritis

Pettit, Allison R. and Gravellese, Ellen M. (2005). Pathogenesis of focal bone loss in inflammatory arthritis. Bone Disease in Rheumatology. (pp. 15-22) edited by Maricic, Michael and Gluck, Oscar S.. Arizona, USA: Lippincott Williams & Wilkins.

Osteoprotegerin

Pettit, A. R. and Gravellese, E. M. (2003). Osteoprotegerin. Targeted therapies in rheumatology. (pp. 359-377) edited by Josef S. Smolen and Peter E. Lipsky. London, United Kingdom: Taylor & Francis.

Identification and isolation of synovial dendritic cells

Pettit, A. R., Cavanagh, L. L. and Thomas, R. (2001). Identification and isolation of synovial dendritic cells. Dendritic Cell Protocols. (pp. 175-187) edited by S. P. Robinson and A. J. Stagg. Totowa USA: Humana Press. doi: 10.1385/1-59259-150-7:175

Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer

Batoon, Lena, Keshvari, Sahar, Irvine, Katharine M, Ho, Eileen, Caruso, Melanie, Patkar, Omkar L, Sehgal, Anuj, Millard, Susan M, Hume, David A and Pettit, Allison R (2024). Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer. Journal of Leukocyte Biology. doi: 10.1093/jleuko/qiae077

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

Keshvari, Sahar, Masson, Jesse J.R., Ferrari-Cestari, Michelle, Bodea, Liviu-Gabriel, Nooru-Mohamed, Fathima, Tse, Brian W.C., Sokolowski, Kamil A., Batoon, Lena, Patkar, Omkar L., Sullivan, Mitchell A., Ebersbach, Hilmar, Stutz, Cian, Parton, Robert G., Summers, Kim M., Pettit, Allison R., Hume, David A. and Irvine, Katharine M. (2024). Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism. American Journal of Physiology-Endocrinology and Metabolism, 326 (2), E149-E165. doi: 10.1152/ajpendo.00347.2023

Macrophage heterogeneity in the single cell era: facts and artefacts

Hume, David A., Millard, Susan M. and Pettit, Allison R. (2023). Macrophage heterogeneity in the single cell era: facts and artefacts. Blood Journal, 142 (16), 1339-1347. doi: 10.1182/blood.2023020597

3152 – HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION

Millard, Susan, Kaur, Simranpreet, Choo, Fang Ming and Pettit, Allison (2023). 3152 – HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION. Experimental Hematology, 124, S125. doi: 10.1016/j.exphem.2023.06.259

Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

Tseng, Hsu‐Wen, Kulina, Irina, Girard, Dorothée, Gueguen, Jules, Vaquette, Cedryck, Salga, Marjorie, Fleming, Whitney, Jose, Beulah, Millard, Susan M., Pettit, Allison R., Schroder, Kate, Thomas, Gethin, Wheeler, Lawrie, Genêt, François, Banzet, Sébastien, Alexander, Kylie A. and Levesque, Jean‐Pierre (2022). Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification. Journal of Bone and Mineral Research, 37 (3), 531-546. doi: 10.1002/jbmr.4482

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Tseng, Hsu-Wen, Girard, Dorothée, Alexander, Kylie A., Millard, Susan M., Torossian, Frédéric, Anginot, Adrienne, Fleming, Whitney, Gueguen, Jules, Goriot, Marie-Emmanuelle, Clay, Denis, Jose, Beulah, Nowlan, Bianca, Pettit, Allison R., Salga, Marjorie, Genêt, François, Bousse-Kerdilès, Marie-Caroline Le, Banzet, Sébastien and Lévesque, Jean-Pierre (2022). Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Research, 10 (1) 22, 22. doi: 10.1038/s41413-022-00188-y

1015 – APPEARANCES CAN BE DECEIVING: MACROPHAGE FRAGMENTATION CONFOUNDS EX VIVO HAEMATOPOIETIC TISSUE ANALYSIS

Pettit, Allison R, Batoon, Lena, Heng, Ostyn, Hume, David, Irvine, Kate, Kaur, Simranpreet, Levesque, Jean-Pierre, Magor, Graham, Millard, Susan, Noll, Jacqueline, Perkins, Andrew, Raggatt, Liza, Sandrock, Cheyenne, Sehgal, Anuj, Sester, David, Opperman, Khatora Shanae, Summers, Kim, Wu, Andy and Zannettino, Andrew (2022). 1015 – APPEARANCES CAN BE DECEIVING: MACROPHAGE FRAGMENTATION CONFOUNDS EX VIVO HAEMATOPOIETIC TISSUE ANALYSIS. Experimental Hematology, 111, S23. doi: 10.1016/j.exphem.2022.07.018

Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease

Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

Millard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058

Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation

Lévesque, Jean-Pierre, Summers, Kim M., Bisht, Kavita, Millard, Susan M., Winkler, Ingrid G. and Pettit, Allison R. (2021). Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation. Experimental Hematology, 103, 1-14. doi: 10.1016/j.exphem.2021.08.011

Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Wu, Andy C., Kaur, Simranpreet, Sun, Lucas W.H., Williams, Kyle, Sandrock, Cheyenne, Ng, Pei Ying, Irvine, Katharine M., Bartnikowski, Michal, Glatt, Vaida, Pavlos, Nathan J. and Pettit, Allison R. (2021). Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. Journal of Bone and Mineral Research, 36 (11), 2214-2228. doi: 10.1002/jbmr.4413

Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches

Lévesque, Jean-Pierre, Summers, Kim M., Millard, Susan, Bisht, Kavita, Winkler, Ingrid G. and Pettit, Allison R. (2021). Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches. Experimental Hematology, 100, 12-31. doi: 10.1016/j.exphem.2021.07.001

Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones

Batoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936, 120936. doi: 10.1016/j.biomaterials.2021.120936

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation

Keshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605

Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1

Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22

Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release

Starobova, Hana, Monteleone, Mercedes, Adolphe, Christelle, Batoon, Lena, Sandrock, Cheyenne J., Tay, Bryan, Deuis, Jennifer R., Smith, Alexandra V., Mueller, Alexander, Nadar, Evelyn Israel, Lawrence, Grace Pamo, Mayor, Amanda, Tolson, Elissa, Levesque, Jean-Pierre, Pettit, Allison R., Wainwright, Brandon J., Schroder, Kate and Vetter, Irina (2021). Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release. Journal of Experimental Medicine, 218 (5) e20201452. doi: 10.1084/jem.20201452

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w

A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system

Grabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M., Wollscheid-Lengeling, Evi, Ozdemir, Derya D., Stables, Jennifer, Luke, Garry A., Ryan, Martin D., Adamson, Antony, Humphreys, Neil E., Sandrock, Cheyenne J., Rojo, Rocio, Verkasalo, Veera A., Mueller, Werner, Hohenstein, Peter, Pettit, Allison R., Pridans, Clare and Hume, David A. (2020). A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system. Journal of Immunology, 205 (11), 3154-3166. doi: 10.4049/jimmunol.2000835

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

Tay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003

Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study

Patel, Rushabh, Lu, Mingyuan, Diermann, Sven Heinrich, Wu, Andy, Pettit, Allison and Huang, Han (2019). Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study. Journal of the Mechanical Behavior of Biomedical Materials, 96, 1-8. doi: 10.1016/j.jmbbm.2019.04.030

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

Alexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms

Levesque, Jean-Pierre, Sims, Natalie A., Pettit, Allison R., Alexander, Kylie A., Tseng, Hsu-Wen, Torossian, Frédéric, Genêt, François, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms. Journal of Bone and Mineral Research, 33 (2), 365-366. doi: 10.1002/jbmr.3346

Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications

Torossian, Frédéric, Guerton, Bernadette, Anginot, Adrienne, Alexander, Kylie A., Desterke, Christophe , Soave, Sabrina, Tseng, Hsu-Wen, Arouche, Nassim, Boutin, Laetitia, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Pettit, Allison R., Clay, Denis, Rochet, Nathalie, Vlachos, Erica, Genet, Guillaume, Debaud, Charlotte, Denormandie, Philippe, Genet, François, Sims, Natalie A., Banzet, Sébastien, Levesque, Jean-Pierre, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications. JCI Insight, 2 (21) e96034. doi: 10.1172/jci.insight.96034

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033

Characterization of normal murine carpal bone development prompts re-evaluation of pathological osteolysis as the cause of human carpal-tarsal osteolysis disorders

Lazarus, Syndia, Tseng, Hsu-Wen, Lawrence, Felicity, Woodruff, Maria Ann, Duncan, Emma Letitia and Pettit, Allison Robyn (2017). Characterization of normal murine carpal bone development prompts re-evaluation of pathological osteolysis as the cause of human carpal-tarsal osteolysis disorders. American Journal of Pathology, 187 (9), 1923-1934. doi: 10.1016/j.ajpath.2017.05.007

Osteomacs and bone regeneration

Batoon, Lena, Millard, Susan Marie, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). Osteomacs and bone regeneration. Current Osteoporosis Reports, 15 (4), 385-395. doi: 10.1007/s11914-017-0384-x

Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis

Tseng, Hsu-Wen, Glant, Tibor T., Brown, Matthew A., Kenna, Tony J., Thomas, Gethin P. and Pettit, Allison R. (2017). Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis. BMC Musculoskeletal Disorders, 18 (1) 228, 228. doi: 10.1186/s12891-017-1600-7

Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells

Karpova, Darja, Ritchey, Julie K., Holt, Matthew S., Abou-Ezzi, Grazia, Monlish, Darlene, Batoon, Lena, Millard, Susan, Spohn, Gabriele, Wiercinska, Eliza, Chendamarai, Ezhil, Yang, Wei, Christ, Stephanie, Gehrs, Leah, Schuettpelz, Laura G., Dembowsky, Klaus, Pettit, Allison R., Rettig, Michael P., Bonig, Halvard and DiPersio, John F. (2017). Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells. Blood, 129 (21), 2939-2949. doi: 10.1182/blood-2016-10-746909

Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration

Alexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

Kaur, Simranpreet, Raggatt, Liza Jane, Batoon, Lena, Hume, David Arthur, Levesque, Jean-Pierre and Pettit, Allison Robyn (2016). Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches. Seminars in Cell and Developmental Biology, 61, 12-21. doi: 10.1016/j.semcdb.2016.08.009

CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

Wu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes

Tseng, Hsu-Wen, Pitt, Miranda E., Glant, Tibor T., McRae, Allan F., Kenna, Tony J., Brown, Matthew A., Pettit, Allison R. and Thomas, Gethin P. (2016). Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes. Arthritis Research and Therapy, 18 (1) 35, 35. doi: 10.1186/s13075-015-0805-0

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche

Lawson, Michelle A., McDonald, Michelle M., Kovacic, Natasa, Khoo, Weng Hua, Terry, Rachael L., Down, Jenny, Kaplan, Warren, Paton-Hough, Julia, Fellows, Clair, Pettitt, Jessica A., Dear, T.Neil, Van Valckenborgh, Els, Baldock, Paul A., Rogers, Michael J., Eaton, Colby L., Vanderkerken, Karin, Pettit, Allison R., Quinn, Julian M.W., Zannettino, Andrew C.W., Phan, Tri Giang and Croucher, Peter I. (2015). Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche. Nature Communications, 6 (8983) 8983, 8983. doi: 10.1038/ncomms9983

Macrophages: Their Emerging Roles in Bone

Sinder, Benjamin P., Pettit, Allison R. and McCauley, Laurie K. (2015). Macrophages: Their Emerging Roles in Bone. Journal of Bone and Mineral Research, 30 (12), 2140-2149. doi: 10.1002/jbmr.2735

Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts

Millard, Susan M., Pettit, Allison R., Ellis, Rebecca, Chan, Jerry K. Y., Raggatt, Liza J., Khosrotehrani, Kiarash and Fisk, Nicholas M. (2015). Intrauterine bone marrow transplantation in osteogenesis imperfecta mice yields donor osteoclasts and osteomacs but not osteoblasts. Stem Cell Reports, 5 (5), 682-689. doi: 10.1016/j.stemcr.2015.09.017

Tissue engineered humanized bone supports human hematopoiesis in vivo

Holzapfel, Boris M., Hutmacher, Dietmar W., Nowlan, Bianca, Barbier, Valerie, Thibaudeau, Laure, Theodoropoulos, Christina, Hooper, John D., Loessner, Daniela, Clements, Judith A., Russell, Pamela J., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2015). Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials, 61, 103-114. doi: 10.1016/j.biomaterials.2015.04.057

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle

Genet, Francois, Kulina, Irina, Vaquette, Cedryck, Torossian, Frederic, Millard, Susan, Pettit, Allison R., Sims, Natalie A., Anginot, Adrienne, Guerton, Bernadette, Winkler, Ingrid G., Barbier, Valerie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline, Hutmacher, Dietmar W. and Levesque, Jean-Pierre (2015). Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle. Journal of Pathology, 236 (2), 229-240. doi: 10.1002/path.4519

Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification

Raggatt, Liza J., Wullschleger, Martin E., Alexander, Kylie A., Wu, Andy C. K., Millard, Susan M., Kaur, Simranpreet, Maugham, Michelle L., Gregory, Laura S., Steck, Roland and Pettit, Allison R. (2014). Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification. American Journal of Pathology, 184 (12), 3192-3204. doi: 10.1016/j.ajpath.2014.08.017

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

Tesch, Greg, Sourris, Karly C., Summers, Shaun A., McCarthy, Domenica, Ward, Micheal S., Borg, Danielle J., Gallo, Linda A., Fotheringham, Amelia K., Pettit, Allison R., Yap, Felicia Y. T., Harcourt, Brooke E., Tan, Adeline L. Y., Kausman, Joshua Y., Nikolic-Paterson, David, Kitching, Arthur R. and Forbes, Josephine M. (2014). Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes. Diabetologia, 57 (9), 1977-1985. doi: 10.1007/s00125-014-3291-z

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse

Jacobsen, Rebecca N., Forristal, Catherine E., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Kaur, Simranpreet, van Rooijen, Nico, Winkler, Ingrid G., Pettit, Allison R. and Levesque, Jean-Pierre (2014). Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse. Experimental Hematology, 42 (7), 547-561. doi: 10.1016/j.exphem.2014.03.009

Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes

Thomas, Gethin P., Duan, Ran, Pettit, Allison R., Weedon,Helen, Kaur, Simranpreet, Smith, Malcolm and Brown, Matthew A. (2013). Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes. BMC Musculoskeletal Disorders, 14 (1) 354, 354. doi: 10.1186/1471-2474-14-354

Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL

Walsh, N. C., Alexander, K. A., Manning, C. A., Karmakar, S. K., Wang, J. F., Weyand, C. M., Pettit, A. R. and Gravallese, E. M. (2013). Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL. Genes and Immunity, 14 (5), 336-345. doi: 10.1038/gene.2013.29

Unraveling macrophage contributions to bone repair

Wu, Andy C., Raggatt, Liza J., Alexander, Kylie A. and Pettit, Allison R. (2013). Unraveling macrophage contributions to bone repair. BoneKEy Reports, 2 (373), 1-1. doi: 10.1038/bonekey.2013.107

Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury model

Raggatt, Liza J., Alexander, Kylie A., Kaur, Simranpreet, Wu, Andy C., MacDonald, Kelli P. A. and Pettit, Allison R. (2013). Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury model. American Journal of Pathology, 182 (5), 1501-1508. doi: 10.1016/j.ajpath.2013.01.046

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

Roberts, Tara L., Ho, Uda, Luff, John, Lee, C. Soon, Apte, Simon H., MacDonald, Kelli P. A., Raggatt, Liza-Jane, Pettit, Allison R., Morrow, Carl A., Waters, Michael J., Chen, Phil, Woods, Rick G., Thomas, Gethin P., St. Pierre, Liam, Farah, Camile S., Clarke, Raymond A., Brown, James A. L. and Lavin, Martin F. (2013). Smg1 haploinsufficiency predisposes to tumor formation and inflammation. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 110 (4), E285-E294. doi: 10.1073/pnas.1215696110

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor

Karpova, D., Dauber, K., Spohn, G., Chudziak, D., Wiercinska, E., Schulz, M., Pettit, A. R., Levesque, J. P., Romagnoli, B., Patel, K., Chevalier, E., Dembowsky, K. and Bonig, H. (2013). The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor. Leukemia, 27 (12), 2322-2331. doi: 10.1038/leu.2013.266

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

Haynes, Katelin R., Pettit, Allison R., Duan, Ran, Tseng, Hsu-Wen, Glant, Tibor T., Brown, Matthew A. and Thomas, Gethin P. (2012). Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Research & Therapy, 14 (6) R253, R253.1-R253.12. doi: 10.1186/ar4096

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation

Winkler, I. G., Pettit, A. R., Raggatt, L. J., Jacobsen, R. N., Forristal, C. E., Barbier, V., Nowlan, B., Cisterne, A., Bendall, L. J., Sims, N. A. and Levesque, J-P. (2012). Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia, 26 (7), 1594-1601. doi: 10.1038/leu.2012.17

β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice

Ruutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia A., Zinkernagel, Martin S., Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert J., Kikly, Kristine, Davies, Julian, Pettit, Allison R., Brown, Matthew A., McGuckin, Michael A. and Thomas, Ranjeny (2012). β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice. Arthritis and Rheumatism, 64 (7), 2211-2222. doi: 10.1002/art.34423

Unravelling the pluripotency paradox in fetal and placental mesenchymal stem cells: Oct-4 expression and the case of the emperor's new clothes

Ryan, Jennifer M., Pettit, Allison R, Guillot, Pascale V, Chan, Jerry K. Y. and Fisk, Nicholas M. (2011). Unravelling the pluripotency paradox in fetal and placental mesenchymal stem cells: Oct-4 expression and the case of the emperor's new clothes. Stem Cell Reviews and Reports, 9 (4), 408-421. doi: 10.1007/s12015-011-9336-5

Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

Alexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Winkler, Ingrid G., Sims, Natalie A., Pettit, Allison R., Barbier, Valérie, Nowlan, Bianca, Helwani, Falak, Poulton, Ingrid J., van Rooijen, Nico van, Alexander, Kylie A., Raggatt, Liza J. and Levesque, Jean-Pierre (2010). Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood, 116 (23), 4815-4828. doi: 10.1182/blood-2009-11-253534

An antibody against the colony-stimulating factor 1 receptor (CSF1R) depletes the resident subset of monocytes and tissue and tumor-associated macrophages but does not inhibit inflammation

MacDonald, Kelli P. A., Palmer, James S., Cronau, Stephen, Seppanen, Elke Jane, Olver, Stuart, Raffelt, Neil C., Kuns, Rachel, Pettit, Allison R., Clouston, Andrew, Wainwright, Brandon J., Branstetter, Dan, Smith, Jeffrey, Paxton, Raymond J., Cerretti, Douglas Pat, Bonham, Lynn, Hill, Geoffrey R. and Hume, David A. (2010). An antibody against the colony-stimulating factor 1 receptor (CSF1R) depletes the resident subset of monocytes and tissue and tumor-associated macrophages but does not inhibit inflammation. Blood, 116 (19), 3955-3963. doi: 10.1182/blood-2010-02-266296

Soluble lymphotoxin is an important effector molecule in GVHD and GVL

Markey, KA, Burman, AC, Banovic, T, Kuns, RD, Raffelt, NC, Rowe, V, Olver, SD, Don, ALJ, Morris, ES, Pettit, AR, Wilson, YA, Robb, RJ, Randall, LM, Korner, H, Engwerda, CR, Clouston, AD, MacDonald, KPA and Hill, GR (2010). Soluble lymphotoxin is an important effector molecule in GVHD and GVL. Blood, 115 (1), 122-132. doi: 10.1182/blood-2009-01-199927

Responses in vivo to purified poly (3-hydroxybutyrate-co-3-hydroxyvalerate) implanted in a murine tibial defect model

Wu, A. C. K., Pettit, A. R., Toulson, S., Grondahl, L., Mackie, E. J. and Cassady, A. I. (2009). Responses in vivo to purified poly (3-hydroxybutyrate-co-3-hydroxyvalerate) implanted in a murine tibial defect model. Journal of Biomedical Materials Research Part A, 91A (3), 845-854. doi: 10.1002/jbm.a.32238

Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation

Markey, KA, Banovic, T, Kuns, RD, Olver, SD, Don, ALJ, Raffelt, NC, Wilson, YA, Raggatt, LJ, Pettit, AR, Bromberg, JS, Hill, GR and MacDonald, KPA (2009). Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation. BLOOD, 113 (22), 5644-5649. doi: 10.1182/blood-2008-12-191833

Osteal macrophages: A new twist on coupling during bone dynamics

Pettit, A. R., Chang, M. K., Hume, D. A. and Raggatt, L. J. (2008). Osteal macrophages: A new twist on coupling during bone dynamics. Bone, 43 (6), 976-982. doi: 10.1016/j.bone.2008.08.128

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

Chang, Ming K., Raggatt, Liza-Jane, Alexander, Kylie A., Kuliwaba, Julia S., Fazzalari, Nicola L., Schroder, Kate, Maylin, Erin R., Ripoll, Vera M, Hume, David A. and Pettit, Allison R. (2008). Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo. The Journal of Immunology, 181 (2), 1232-1244. doi: 10.4049/jimmunol.181.2.1232

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

Pettit, Allison R., Hume, David A. and Raggatt, Liza-Jane (2008). Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats. Bone, 42 (4), 825-825. doi: 10.1016/j.bone.2007.12.217

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

Ripoll, V. M, Meadows, N. A., Raggatt, L. J., Chang, M. K., Pettit, A. R., Cassady, A. I. and Hume, D. A. (2008). Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene, 413 (1-2), 32-41. doi: 10.1016/j.gene.2008.01.014

Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-κB

Martin, E., Capini, C., Duggan, E., Lutzky, V. P., Stumbles, P., Pettit, A. R., O'Sullivan, B. and Thomas, R. (2007). Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-κB. Arthritis And Rheumatism, 56 (7), 2255-2266. doi: 10.1002/art.22655

Identification and isolation of synovial dendritic cells

Pettit, Allison R., Cavanagh, Lois, Boyce, Amanda, Padmanabha, Jagadish, Peng, Judy and Thomas, Ranjeny (2007). Identification and isolation of synovial dendritic cells. Methods in Molecular Medicine, 136, 165-181. doi: 10.1007/978-1-59745-402-5_12

RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis

Pettit, A. R., Walsh, N. C., Manning, C., Goldring, S. R. and Gravallese, E. M. (2006). RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis. Rheumatology, 45 (9), 1068-1076. doi: 10.1093/rheumatology/kel045

Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): A rose by any other name...

Li, L., Pettit, A. R., Gregory, L. S. and Forwood, M. R. (2006). Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): A rose by any other name.... Cytokine & Growth Factor Reviews, 17 (3), 203-216. doi: 10.1016/j.cytogfr.2006.01.005

Differential transcriptional effects of PTH and estrogen during anabolic bone formation

von Stechow, D, Zurakowski, D, Pettit, AR, Muller, R, Gronowicz, G, Chorev, M, Otu, H, Libermann, T and Alexander, JM (2004). Differential transcriptional effects of PTH and estrogen during anabolic bone formation. Journal of Cellular Biochemistry, 93 (3), 476-490. doi: 10.1002/jcb.20174

ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation

Brown, C, Gaspar, J, Pettit, A, Lee, R, Gu, XS, Wang, H, Manning, C, Voland, C, Goldring, SR, Goldring, MB, Libermann, TA, Gravallese, EM and Oettgen, P (2004). ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. Journal of Biological Chemistry, 279 (13), 12794-12803. doi: 10.1074/jbc.M308593200

Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis

Jacobs, J. P., Pettit, A. R., Shinohara, M. L., Jansson, M., Cantor, H., Gravallese, E. M., Mathis, D. and Benoist, C. (2004). Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. Arthritis And Rheumatism, 50 (8), 2685-2694. doi: 10.1002/art.20381

Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor alpha

Gravallese, E. M., Pettit, A. R., Lee, R., Madore, R., Manning, C., Tsay, A., Gaspar, J., Goldring, M. B., Goldring, S. R. and Oettgen, P. (2003). Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor alpha. Annals of The Rheumatic Diseases, 62 (2), 100-107. doi: 10.1136/ard.62.2.100

Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor a in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappa B-mediated induction of the ets transcription factor ESE-1

Grall, Franck, Gu, Xuesong, Tan, Lujian, Cho, Je-Yoel, Inan, Mehmet Sait, Pettit, Allison R., Thamrongsak, Usanee, Choy, Bob K., Manning, Cathy, Akbarali, Yasmin, Zerbini, Luiz, Rudders, Susan, Goldring, Steven R., Gravallese, Ellen M., Oettgen, Peter, Goldring, Mary B. and Libermann, Towia A. (2003). Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor a in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappa B-mediated induction of the ets transcription factor ESE-1. Arthritis and Rheumatism, 48 (5), 1249-1260. doi: 10.1002/art.10942

Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis

Mould, Arne W., Tonks, Ian D., Cahill, Marian M., Pettit, Allison R., Thomas, Ranjeny, Hayward, Nicholas K. and Kay, Graham F. (2003). Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis. Arthritis and Rheumatism, 48 (9), 2660-2669. doi: 10.1002/art.11232

Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis

Ji, H, Pettit, A, Ohmura, K, Ortiz-Lopez, A, Duchatelle, V, Degott, C, Gravallese, E, Mathis, D and Benoist, C (2002). Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis. Journal of Experimental Medicine, 196 (1), 77-85. doi: 10.1084/jem.20020439

Increase in expression of receptor activator of nuclear factor kappa B at sites of bone erosion correlates with progression of inflammation in evolving collagen-induced arthritis

Lubberts, Erik, Oppers-Walgreen, Birgitte, Pettit, Allison R., van den Bersselaar, Liduine, Joosten, eo A. B., Goldring, Steven R., Gravallese, Ellen M. and van den Berg, Wim B. (2002). Increase in expression of receptor activator of nuclear factor kappa B at sites of bone erosion correlates with progression of inflammation in evolving collagen-induced arthritis. Arthritis And Rheumatism, 46 (11), 3055-3064. doi: 10.1002/art.10607

Nuclear RelB(+) cells are found in normal lymphoid organs and in peripheral tissue in the context of inflammation, but not under normal resting conditions

Thompson, Angus G., Pettit, Allison R., Padmanabha, Jagdish, Mansfield, Helen, Frazer, Ian H ., Strutton, Geoff M. and Thomas, Ranjeny (2002). Nuclear RelB(+) cells are found in normal lymphoid organs and in peripheral tissue in the context of inflammation, but not under normal resting conditions. Immunology and Cell Biology, 80 (2), 164-169. doi: 10.1046/j.1440-1711.2002.01070.x

TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis

Pettit, Allison R., Ji, Hong, von Stechow, Dietrich, Muller, Ralph, Goldring, Steven R., Choi, Yongwon, Benoist, Christophe and Gravallese, Ellen M. (2001). TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. American Journal of Pathology, 159 (5), 1689-1699. doi: 10.1016/S0002-9440(10)63016-7

Association of clinical, radiological and synovial immunopathological responses to anti-rheumatic treatment in rheumatoid arthritis

Pettit, AR, Weedon, H, Ahern, M, Zehntner, S, Frazer, IH, Slavotinek, J, Au, V, Smith, MD and Thomas, R (2001). Association of clinical, radiological and synovial immunopathological responses to anti-rheumatic treatment in rheumatoid arthritis. Rheumatology, 40 (11), 1243-1255. doi: 10.1093/rheumatology/40.11.1243

Comparison of differentiated dendritic cell infiltration of autoimmune and osteoarthritis synovial tissue

Pettit, A. R., Ahern, M. J., Zehntner, S., Smith, M. D. and Thomas, R. (2001). Comparison of differentiated dendritic cell infiltration of autoimmune and osteoarthritis synovial tissue. Arthritis And Rheumatism, 44 (1), 105-110. doi: 10.1002/1529-0131(200101)44:1<105::AID-ANR14>3.0.CO;2-3

Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates

Pettit, A. R., MacDonald, K. P., OSullivan, B. J. and Thomas, R. (2000). Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates. Arthritis And Rheumatism, 43 (4), 791-800. doi: 10.1002/1529-0131(200004)43:4<791::AID-ANR9>3.0.CO;2-E

RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function

O'Sullivan, Brendan J., MacDonald, Kelli P. A., Pettit, Allison R. and Thomas, Ranjeny (2000). RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. Proceedings of the National Academy of Sciences of the United States of America, 97 (21), 11421-11426. doi: 10.1073/pnas.97.21.11421

Dendritic cells and the pathogenesis of rheumatoid arthritis

Thomas, R., MacDonald, K. P. A., Pettit, A. R., Cavanagh, L. L., Padmanabha, J. and Zehntner, S. (1999). Dendritic cells and the pathogenesis of rheumatoid arthritis. Journal of Leukocyte Biology, 66 (2), 286-292. doi: 10.1002/jlb.66.2.286

Dendritic cells: the driving force behind autoimmunity in rheumatoid arthritis?

Pettit, Allison R. and Thomas, Ranjeny (1999). Dendritic cells: the driving force behind autoimmunity in rheumatoid arthritis?. Immunology and Cell Biology, 77 (5), 420-427. doi: 10.1046/j.1440-1711.1999.00855.x

Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-101

MacDonald, Kelli P. A., Pettit, Allison R., Quinn, Christopher, Thomas, Gregory J. and Thomas, Ranjeny (1999). Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-101. The Journal of Immunology, 163 (10), 5599-5607.

Inhibition of Ku autoantigen binding activity to the E2F motif after ultraviolet B irradiation of melanocytic cells

Pedley, J., Pettit, A. and Parsons, P. G. (1998). Inhibition of Ku autoantigen binding activity to the E2F motif after ultraviolet B irradiation of melanocytic cells. Melanoma Research, 8 (6), 471-481. doi: 10.1097/00008390-199812000-00001

Nuclear localization of RelB is associated with effective antigen-presenting cell function

Pettit, Allison R., Quinn, Christopher, MacDonald, Kellie P. A., Cavanagh, Lois L., Thomas, Greg, Townsend, Wendy, Handel, Malcolm and Thomas, Ranjeny (1997). Nuclear localization of RelB is associated with effective antigen-presenting cell function. Journal of Immunology, 159 (8), 3681-3691.

Inhibition of retinoblastoma protein translation by UVB in human melanocytic cells and reduced cell cycle arrest following repeated irradiation

Pedley, J., Ablett, E. M., Pettit, A., Meyer, J., Dunn, I. S., Sturm, R. A. and Parsons, P. G. (1996). Inhibition of retinoblastoma protein translation by UVB in human melanocytic cells and reduced cell cycle arrest following repeated irradiation. Oncogene, 13 (6), 1335-1342.

1511 Macrophages regulate endothelial progenitors’ quiescence and self-renewal during homeostasis and cutaneous wound healing via paracrine signaling

Sim, S., Kaur, S., Styke, C., Millard, S., Blumenthal, A., Pettit, A. and Khosrotehrani, K. (2023). 1511 Macrophages regulate endothelial progenitors’ quiescence and self-renewal during homeostasis and cutaneous wound healing via paracrine signaling. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1528

Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer

Batoon, Lena, Keshvari, Sahar, Irvine, Katharine, Caruso, Melanie, Patkar, Omkar, Sehgal, Anuj, Millard, Susan, Hume, David and Pettit, Allison (2023). Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX, United States, 9-12 September 2022. Hoboken, NJ, United States: Wiley-Blackwell.

HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION

Millard, Susan, Kaur, Simranpreet, Choo, Fang Ming and Pettit, Allison (2023). HSC NICHE MOLECULAR DECONVOLUTION TOWARD IMPROVED UNDERSTANDING OF INTRINSIC AND EXTRINSIC HSC REGULATION. 52nd Annual Meeting of the International-Society-for-Experimental-Hematology (ISEH), New York Ny, Aug 17-20, 2023. NEW YORK: ELSEVIER SCIENCE INC.

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

Non-genotoxic conditioning facilitates tolerance induction through stable mixed hematopoietic chimerism of gene modified bone marrow

Hasan, M. A., Pettit, A. R. and Steptoe, R. J. (2019). Non-genotoxic conditioning facilitates tolerance induction through stable mixed hematopoietic chimerism of gene modified bone marrow. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October, 2019. Weinheim, Germany: Wiley. doi: 10.1002/eji.201970400

Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology

Pettit, Allison, Batoon, Lena, Millard, Susan, Wu, Andy and Raggatt, Liza (2019). Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology. Annual Meeting of the American Society for Bone and Mineral Research, Orlando, FL, United States, 20-23 September, 2019. Hoboken, NJ, United States: Wiley-Blackwell Publishing Asia.

Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation

Millard, Susan, Wu, Andy, Kaur, Simran, He, Yaowu, Batoon, Lena, Hooper, John and Pettit, Allison (2018). Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation. Annual Meeting of the American Society for Bone and Mineral Research, Montréal, Quebéc, Canada, Sep 28-Oct 01, 2018. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1002/jbmr.3621

Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries

Tseng, Hsu-Wen, Alexander, Kylie, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Genet, Francois, Torossian, Frederic, Guerton, Bernadette, Anginot, Adrienne, Fleming, Whitney, Millard, Susan, Pettit, Allison, Sims, Natalie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Levesque, Jean Pierre (2018). Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries. Annual Meeting of the American Society for Bone and Mineral Research, Montreal Canada, September 28 - October 1 2018. Hoboken, NJ United States: Wiley.

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo

Goh, Sal Lee, Levesque, Jean-Pierre, Pettit, Allison, Barbier, Valerie, Jeanclos, Cecile and Winkler, Ingrid (2016). Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier.

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

Levesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Kaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages

Kaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157

Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice

Tesch, G. H., Sourris, K. C., Summers, S. A., Mccarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. and Forbes, J. M. (2014). Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301

Endochondral Bone Formation and Advanced Enthesitis Are Key Features Of Proteoglycan Induced Spondylitis Mouse Model Of Ankylosing Spondylitis

Thomas, Gethin P., Tseng, Hsu-Wen, Pettit, Allison, Glant, Tibor T., McRae, Allan and Brown, Matthew A. (2013). Endochondral Bone Formation and Advanced Enthesitis Are Key Features Of Proteoglycan Induced Spondylitis Mouse Model Of Ankylosing Spondylitis. 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego CA, United States, 25-30 October 2013. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/art.38216

Endochondral bone formation and advanced enthesitis are key features of PGISp mouse model of ankylosing spondylitis

Tseng, H., Pettit, A., Glant, T., Brown, M. and Thomas, G. (2013). Endochondral bone formation and advanced enthesitis are key features of PGISp mouse model of ankylosing spondylitis. 54th Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with the Rheumatology Health Professionals Association, Perth, WA Australia, 18 -22 May 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12139

Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral Ossification

Pettit, A., Raggatt, L., Wullschleger, M., Alexander, K., Steck, R., Kaur, S. and Wu, A. (2013). Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral Ossification. Annual Meeting of the American Society for Bone and Mineral Research, Baltimore MD United States, 4-7 October 2013. Hoboken, NJ United States: Wiley-Blackwell.

Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages

Jacobsen, Rebecca, Pettit, Allison, Barbier, Valerie, Nowlan, Bianca, Raggatt, Liza, Winkler, Ingrid and Levesque, Jean-Pierre (2013). Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages. 42nd Annual Scientific Meeting of ISEH - Society for Hematology and Stem Cells, Vienna, Austria, 22-25 August 2013. Philadelphia, PA United States: Elsevier Inc. doi: 10.1016/j.exphem.2013.05.230

Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages

Jacobsen, Rebecca, Pettit, Allison R., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Forristal, Catherine E., Winkler, Ingrid G. and Levesque, Jean-Pierre (2013). Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. WASHINGTON: AMER SOC HEMATOLOGY.

Expression profiling in spondylarthropy synovial biopsies highlights inflammatory gene changes in conjunction with altered Wnt signalling

Thomas, G., Duan, R., Weedon, H., Maylin, E., Pettit, A., Smith, M. and Brown, M. (2012). Expression profiling in spondylarthropy synovial biopsies highlights inflammatory gene changes in conjunction with altered Wnt signalling. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting, Canberra, Australia, 12-15 May 2012. MALDEN: WILEY-BLACKWELL. doi: 10.1111/j.1445-5994.2012.02760.x

Wnt signalling inhibition as a potential therapeutic in ankylosing spondylitis

Haynes, K. H., Pettit, A. P., Duan, R., Tseng, H., Kniessel, M., Glant, T. T., Brown, M. A. and Thomas, G. P. (2012). Wnt signalling inhibition as a potential therapeutic in ankylosing spondylitis. 8th International Congress on Spondyloarthritis, Granada, Spain, 9-13 May 2012. Ospedaletto, Italy: Pacini Editore SpA.

Altered Wnt-Signalling Links Inflammation and Bony Ankylosis in a Mouse Model of Ankylosing Spondylitis

Thomas, G, Duan, R, Pettit, A, Glant, T and Brown, M (2011). Altered Wnt-Signalling Links Inflammation and Bony Ankylosis in a Mouse Model of Ankylosing Spondylitis. Unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL.

B Cells Do Not Influence Intramembranous Bone Modelling in Vivo

Pettit, A. R., Kaur, S., Alexander, K. A., MacDonald, K. P. A. and Raggatt, L. J. (2011). B Cells Do Not Influence Intramembranous Bone Modelling in Vivo. IOF Regionals 2nd Asia-Pacific Osteoporosis and Bone Meeting / ANZBMS Annual Scientific Meeting held with the JSBMR, Gold Coast, QLD Australia, 4-8 September 2011. London, United Kingdom: Springer.

Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis

Levesque, Jean-Pierre, Bendall, Linda J., Pettit, Allison R., Raggatt, Liza, Jacobsen, Rebecca, Barbier, Valarie, Nowlan, Bianca, Shen, Yi Shen, Sims, Natalie A. and Winkler, Ingrid G. (2011). Mobilizing agents G-CSF, cyclophosphamide or AMD3100 (Plerixafor) Have distinct effects on osteoblasts, hematopoietic stem cell niches, and B-Lymphopoiesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego CA, United States, 10-13 December 2011. Washington, DC, United States: American Society of Hematology.

Both DKK-1 and sost are suppressed during late stage disease development in a mouse model of ankylosing spondylitis

Thomas, G., Duan, R., Pettit, A., Glant, T. and Brown, M. (2010). Both DKK-1 and sost are suppressed during late stage disease development in a mouse model of ankylosing spondylitis. Seventh International Congress on Spondyloarthropathies, Gent, Belgium, 7 - 9 October 2010. Ospedaletto, PI, Italy: Pacini Editore SpA.

DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS

Jacobsen, RN, Levesque, JP, Barbier, V, Raggatt, LJ and Pettit, AR (2010). DEPLETION OF BONE MARROW PHAGOCYTES CAUSES THE MOBILIZATION OF LONG-TERM RECONSTITUTING HEMATOPOIETIC STEM CELLS. 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells, Melbourne AUSTRALIA, SEP 15-18, 2010. NEW YORK: ELSEVIER SCIENCE INC.

Conventional dendritic cells are the critical donor APC presenting alloantigen after BMT

Markey, K, Banovic, T, Kuns, R, Raffelt, N, Olver, S, Don, A, Wilson, Y, Pettit, A, Bromberg, J, Hill, G and MacDonald, K (2009). Conventional dendritic cells are the critical donor APC presenting alloantigen after BMT. 35th Annual Meeting of the European-Group-for-Blood-and-Marrow-Transplantation, Goteborg Sweden, Mar 29-Apr 01, 2009. LONDON: NATURE PUBLISHING GROUP.

Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy

Levesque, J. P., Raggatt, L. J., Pettit, A. R., Sims, N. A., Bendall, L. J. and Helwani, F. (2009). Endosteal Macrophages Maintain the Hematopoietic Stem Cell (Hsc) Niche and Participate in Hsc Mobilization Induced by G-Csf or Chemotherapy. 38th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Athens, Greece, 9-12 September 2009. NEW YORK: ELSEVIER SCIENCE INC.

Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing

Alexander, K. A., Raggatt, L., Chang, M., Maylin, E., Muller, R., Kohler, T., Wu, A., Hume, D. and Pettit, A. (2009). Osteomacs are Critical for Optimal Intramembranous Bone Formation in a Tibial Defect Model of Bone Healing. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, Colorado, USA, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.

Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing

Alexander, K. A., Raggatt, L. J., Chang, M. K., Maylin, E. R., Muller, R., Kohler, T., Wu, A. C. K., Hume, D. A. and Pettit, A. R. (2009). Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, NSW, Australia, 21-25 March 2009. United States: Elsevier. doi: 10.1016/j.bone.2009.01.076

Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization

Pettit, A. R., Sims, N. A., Winkler, I. G., Alexander, K. A., Helwani, F., Raggatt, L. J. and Levesque, J. P. (2009). Osteomacs maintain the endosteal hematopoietic stem cell niche and participate in mobilization. 2nd Joint Meeting of the International Bone and Mineral Society/Australian New Zealand Bone and Mineral Society, Sydney, Australia, 21-25 March, 2009. United States: Elsevier Inc.. doi: 10.1016/j.bone.2009.01.082

Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling

Raggatt, L., Chang, M., Alexander, K., Maylin, E., Walsh, N., Gravallese, E., Hume, D. and Pettit, A. (2009). Osteomacs: Osteoclast Precursors During Inflammatory Bone Disease but Regulators of Physiologic Bone Remodeling. Australian Society of Bone and Mineral Research (ASBMR) 31st Annual Meeting, Denver, CO, United States, 11-15 September, 2009. United States: American Society for Bone and Mineral Research.

Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling

Raggatt, L. J., Chang, M. K., Alexander, K. A., Maylin, E. R., Walsh, N. C., Gravallese, E. M., Hume, D. A. and Pettit, A. R. (2009). Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, Australia, 21-25 March, 2009. New York: Elsevier Science. doi: 10.1016/j.bone.2009.01.300

Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation

Chang, M. K., Pettit, A. R., Schroder, K., Ripoll, V. M., Alexander, K. A., Hume, D. A. and Raggatt, L. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation. ECTS 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, NY, U.S.A.: Springer New York. doi: 10.1007/s00223-008-9118-5

Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization

Alexander, K. A., Chang, M. K., Hume, D. A., Pettit, A. R., Raggatt, L., Ripoli, V. M. and Schroder, K. (2008). Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralization. 35th European Symposium on Calcified Tissues, Barcelona, Spain, 24-28 May 2008. New York, USA: Springer. doi: 10.1007/s00223-008-9118-5

Analysis of in vivo responses to hydrogen peroxide purified PHBV biomaterial implanted in a murine tibial defect

Wu, A. C. K., Toulson, S., Pettit, A., Grondahl, L., Mackie, E. J. and Cassady, A. I. (2007). Analysis of in vivo responses to hydrogen peroxide purified PHBV biomaterial implanted in a murine tibial defect. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, U.S.A, 16-19 Sep 2007. Washington, D. C.: American Society for Bone and Mineral Research.

Osteal Macrophages: Novel regulators of Bone Formation

Raggatt, L. J., Chang, M. K., Alexander, K. A., Kuiliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal Macrophages: Novel regulators of Bone Formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, 16th -19th September, 2007. Washington, D.C., United States: American Society for Bone and Mineral Research.

Osteal macrophages: Novel regulators of bone formation

Raggatt, L. J., Alexander, K. A., Kuliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal macrophages: Novel regulators of bone formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, United States, 16-19 September 2007.

Primary Murine Osteoblast Cultures Contain Macrophages that Enhance Osteoblast Mineralisation

Chang, M., Hume, D. A., Pettit, A. R., Raggatt, L., Ripoll, V. M. and Schroder, K. (2007). Primary Murine Osteoblast Cultures Contain Macrophages that Enhance Osteoblast Mineralisation. 29th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Honolulu, Hawaii, USA, 16th - 19th September, 2007. Washington, D. C.: American Society for Bone and Mineral Research.

The endosteal bone niche contains macrophages that regulate osteoblast function

Pettit, A. R., Chang, M. K., Alexander, K. A., Wu, A. C., Hume, D. A. and Raggatt, L. J. (2007). The endosteal bone niche contains macrophages that regulate osteoblast function. 17th Scientific Meeting of the International Bone & Mineral Society, Montreal, Canada, 24-29 June 2007. New York: Elsevier Science. doi: 10.1016/j.bone.2007.04.166

RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis

Pettit, A. R., Walsh, N. C., Goldring, S. R. and Gravallese, E. M. (2005). RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis. 27th Annual Meeting of the American Society for Bone and Mineral Research, Nashville, TN, United States, 23-27 September 2005. WASHINGTON: AMER SOC BONE & MINERAL RES.

RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis

Pettit, A. R., Walsh, N. C., Manning, C., Goldring, S. R. and Gravallese, E. M. (2005). RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis. 27th Annual Meeting of the American Society for Bone and Mineral Research, Nashville, Tennessee, U.S.A., 23-27 September 2005. Washington, D.C., U.S.A.: American Society for Bone and Mineral Research.

RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis

Gravallese E. M., Walsh N. C., Manning C. A., Goldring S. R. and Pettit A. R. (2005). RANKL protein is expressed at the pannus-bone interface at sites of erosion in rheumatoid arthritis. 69th Annual Scientific Meeting of the American College of Rheumatology/40th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Diego, Ca, USA, 12-17 November 2005. Hoboken. N.J., USA: John Wiley & Sons.

The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss

Walsh, N. C., Pettit, A. R., Manning, C., Wang, J., McHugh, K. P. and Gravallese, E. M. (2005). The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss. 69th Annual Scientific Meeting of the American College of Rheumatology/40th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Diego, Ca, USA, 12-17 November 2005. Hoboken. N.J., USA: John Wiley & Sons.

The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss

Walsh, N. C., Pettit, A. R., Manning, C., Wang, J., McHugh, K. P. and Gravallese, E. M. (2005). The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss. The American Society for Bone and Mineral Research 27th Annual Meeting, Nashville, Tennessee, USA, 22 - 27 September 2005. Washington, D. C., USA: American Society for Bone and Mineral Research.

The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss

Walsh, N. C., Pettit, A. R., Manning, C. A., Wang, J. F., McHugh, K. P. and Gravallese, E. M. (2005). The expression of novel human RANKL mRNAs in cell types associated with inflammatory bone loss. 69th Annual Scientific Meeting of the American College of Rheumatology/40th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, United States, 12-17 November 2005. HOBOKEN: WILEY-BLACKWELL.

The NFAT family of transcription factors may be key regulators of the RANKL gene in T cells

Pettit, A. R., Manning, C., Goldring, S. R., Libermann, T., Peng, S. I. and Gravallese, E. M. (2003). The NFAT family of transcription factors may be key regulators of the RANKL gene in T cells. 25th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis Minnesota, 19-23 September 2003. Malden, MA United States: Wiley-Blackwell Publishing.

The NFAT family of transcription factors may be key regulators of the RANKL gene in T cells

Pettit, A. R., Manning, C., Goldring, S. R., Libermann, T., Peng, S. L. and Gravallese, E. M. (2003). The NFAT family of transcription factors may be key regulators of the RANKL gene in T cells. 25th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, USA, 19-23 September 2003.

Angiopoietin-1 is expressed in RA synovium and is induced by TNF-alpha in cultured synovial fibroblasts

Pettit, A. R., Gravallese, E. M., Manning, C., Tsay, A., Madore, R., Gaspar, J., Goldring, S. R. and Oettgen, P. (2001). Angiopoietin-1 is expressed in RA synovium and is induced by TNF-alpha in cultured synovial fibroblasts. ACR/ARHP Annual Scientific Meeting, San Francisco CA, United States, 10-15 November 2001. NEW YORK: WILEY-LISS.

Kinetic study of RANK and RANKL expression during collagen-induced arthritis

Lubberts, E., Oppers, B., Pettit, A., van den Bersselaar, L., Smits, D., Joosten, L., Goldring, S., Gravellese, E. and van den Berg, W. (2001). Kinetic study of RANK and RANKL expression during collagen-induced arthritis. ACR/ARHP Annual Scientific Meeting, San Francisco CA, United States, 10-15 November 2001. NEW YORK: WILEY-LISS.

TRANCE/RANKL knockout mice are protected from bone erosion in the K/BxN serum transfer model of arthritis

Pettit, A. R., Ji, H., von Stechow, D., Mueller, R., Choi, Y., Goldring, S. R., Benoist, C. and Gravallese, E. M. (2001). TRANCE/RANKL knockout mice are protected from bone erosion in the K/BxN serum transfer model of arthritis. ACR/ARHP Annual Scientific Meeting, San Francisco CA, United States, 10-15 November 2001. NEW YORK: WILEY-LISS.

Rheumatoid arthritis clinical activity and radiological progression are related to synovial dendritic cell, lymphocyte and macrophage infiltration and TNF alpha expression

Pettit, A. R., Weedon, H., Ahern, M., Zehntner, S., Slavotinek, J., Au, V., Smith, M. D. and Thomas, R. (2000). Rheumatoid arthritis clinical activity and radiological progression are related to synovial dendritic cell, lymphocyte and macrophage infiltration and TNF alpha expression. American College of Rheumatology Annual Scientific Meeting, Philadelphia, PA, USA, 28 October - 2 November 2000.

Nuclear localisation of relB is associated with potent antigen presenting cell function

Thomas, R., Pettit, A., Quinn, Christopher, MacDonald, K. and Cavanagh, L. (1997). Nuclear localisation of relB is associated with potent antigen presenting cell function. AAAAI/AAI/CIS Joint Meeting, -, 21st – 26th February, 1997. Elseiver BV. doi: 10.1016/S0091-6749(97)81067-6

Rheumatoid arthritis synovial tissue and not synovial fluid, DC express high levels of active nuclear RelB

Pettit, A. R., Quinn, C., Cavanagh, L. L., Thomas, G., Townsend, W., Handel, M. and Thomas, R. (1997). Rheumatoid arthritis synovial tissue and not synovial fluid, DC express high levels of active nuclear RelB. -, -, -.

Rheumatoid synovial fluid dendritic cells are resistant to the inhibitory effects of IL-10

Thomas, R., Macdonald, K., Moore, K., Pettit, A., Quinn, C., Thomas, G. and OSullivan, B. (1997). Rheumatoid synovial fluid dendritic cells are resistant to the inhibitory effects of IL-10. 61st National Scientific Meeting of the American College of Rheumatology and the 32nd National Scientific Meeting of the Association of Rheumatology Health Professionals, Washington D.C., U.S., 8-12 November 1997. Hoboken, NJ United States: John Wiley & Sons.

Nuclear RelB+ differentiated dendritic cells and the pathogenesis of synovial inflammation

Pettit, Allison Robyn (2000). Nuclear RelB+ differentiated dendritic cells and the pathogenesis of synovial inflammation. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/d8a6ec2