Dr Johan Rosengren

ARC Future Fellow

School of Biomedical Sciences
Faculty of Medicine

Affiliate Senior Research Fellow

Institute for Molecular Bioscience
j.rosengren@uq.edu.au
+61 7 336 51403

Overview

Dr Rosengren is an ARC Future Fellow at the School of Biomedical Sciences, University of Queensland. He completed his PhD, which focused on structure-activity relationships of antimicrobial peptides, under the supervision of Professor David Craik at the Institute for Molecular Bioscience, UQ, in 2003. After two years of post-doctoral work at IMB he moved to Sweden in 2005 to take up a position as Assistant Professor at Linnaeus University, Kalmar. During 2008-2009 he held a joint appointment between Linnaeus University and Uppsala University. In 2009 he was awarded the Swedish “Docent” title before returning to University of Queensland as a Senior Research Officer, funded by an NHMRC Career Development Award and an ARC Future Fellowship. Dr Rosengren’s research focuses on structure activity relationships of bioactive peptides, in particular peptide hormones and the use of NMR spectroscopy in the design of novel peptide drug leads.

Qualifications

  • Doctor of Philosophy, The University of Queensland
  • Master of Biomedical Chemistry, University of Kalmar

Publications

  • Deuis, Jennifer R., Dekan, Zoltan, Wingerd, Joshua S., Smith, Jennifer J., Munasinghe, Nehan R., Bhola, Rebecca F., Imlach, Wendy L., Herzig, Volker, Armstrong, David A., Rosengren, K. Johan, Bosmans, Frank, Waxman, Stephen G., Dib-Hajj, Sulayman D., Escoubas, Pierre, Minett, Michael S., Christie, Macdonald J., King, Glenn F., Alewood, Paul F., Lewis, Richard J., Wood, John N. and Vetter, Irina (2017) Pharmacological characterisation of the highly Nav1.7 selective spider venom peptide Pn3a. Scientific Reports, 7 . doi:10.1038/srep40883

  • Franke, Bastian, Jayasena, Achala S., Fisher, Mark F., Swedberg, Joakim E., Taylor, Nicolas L., Mylne, Joshua S. and Rosengren, K. Johan (2016) Diverse cyclic seed peptides in the Mexican zinnia (Zinnia haageana). Biopolymers, 106 6: 806-817. doi:10.1002/bip.22901

  • Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016) Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 10: 2202-2212. doi:10.1002/bit.25993

View all Publications

Supervision

  • Doctor Philosophy

  • Doctor Philosophy

  • Doctor Philosophy

View all Supervision

Publications

Book Chapter

  • Rosengren, K. Johan, Daly, N. L. and Craik, D. J. (2009). NMR of peptide toxins. In Graham A. Webb (Ed.), Annual reports on NMR Spectroscopy x ed. (pp. 89-147) Oxford England U.K.: Academic Press Elsevier.

Journal Article

Conference Publication

  • Cardoso, F. C., Dekan, Z., Anangi, R., Rosengren, K. J., Erickson, A., Vetter, I., Herzig, V., Alewood, P., King, G. F. and Lewis, R. J. (2014). Discovery of voltage-gated sodium channel inhibitors from tarantula venoms. In: Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, (). 19-23 October 2014.

  • Craik, D. J., Conibear, A. C., Rosengren, K. J., Daly, N. L. and Henriques, S. T. (2013). Structure Activity Relationships for the Cyclic Cystine Ladder Motif of theta-Defensins. In: Biopolymers. 23rd American Peptide Symposium, Waikoloa Hi, (239-239). Jun 22-27, 2013.

  • Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. In: Proceedings of the 32nd European Peptide Symposium. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, (S48-S48). 02-07 September 2012. doi:10.1002/psc.2448

  • Ragnarsson, Lotten, Wang, Ching-I. Anderson, Andersson, Åsa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2012). The allosteric binding site for rho-TIA on the extracellular surface of the alpha 1B-Adrenoceptor. In: 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous, 17th World Congress of the International Society on Toxinology & Venom Week 2012, 4th International Scientific Symposium on All Things Venomous. 17th World Congress of the International-Society-on-Toxinology (IST)/Venom Week/4th International Scientific Symposium on All Things Venomous, Honolulu, Hawaii, United States, (164-164). 8-13 July 2012. doi:10.1016/j.toxicon.2012.04.137

  • Haugaard-Kedstrom, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Craik, D. J., Wade, J. D. and Rosengren, K. J. (2010). Characterisation of the human INSL5 solution structure. In: EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, (154-154). 5-9 September 2010. doi:10.1002/psc.1303

  • Manuel Plan, Rosengren, K. Johan, Sando, Lillian, Daly, Norelle L. and Craik, David J. (2010). Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis. In: Proceedings of the 1st International Conference on Circular Proteins. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, (647-658). 18-21 October 2009. doi:10.1002/bip.21409

  • Haugaard-Kedström, M., Hossain, M. A., Daly, N. L., Bathgate, R. A. D., Wade, J. D., Craik, D. J. and Rosengren, K. J. (2010). Structural characterization of the relaxin-3IINSL5 chimera peptide: A selective RXFP3 and RXFP4 agonist. In: EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, (39-39). 5-9 September 2010. doi:10.1002/psc.1301

  • Daly, Norelle L., Chen, Yi K., Rosengren, K. Johan, Marx, Ute C., Phillips, Martin L., Waring, Alan J., Wang, Wei, Lehrer, Robert I. and Craik, Robert I. (2009). Retrocyclin-2: A potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. In: Susan Del Valle, Emanuel Escher and W illiam D. Lubell, Peptides for youth: The proceedings of the 20th American Peptide Symposium. 20th American Peptide Society Symposium, Montreal, Canada, (577-578). 26-30 June 2007. doi:10.1007/978-0-387-73657-0_254

  • Rosengren, K. Johan, Bathgate, Ross A. D., Craik, David J., Daly, Norelle L., Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter and Wade, John D. (2009). Structural insights into the function of relaxins. In: Annals of the New York Academy of Sciences: Relaxin and Related Peptides Fifth International Conference. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, (20-26). 18-23 May, 2008. doi:10.1111/j.1749-6632.2009.03833.x

  • Haugaard-Jonsson, Linda M., Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Wade, John D., Craik, David J. and Rosengren, K. Johan (2009). Structural properties of relaxin chimeras: NMR characterization of the R3/I5 relaxin peptide. In: Annals of the New York Academy of Sciences: Relaxin and Related Peptides Fifth International Conference. Relaxin and Related Peptides Fifth International Conference, Maui, Hawaii, USA, (27-30). 18-23 May, 2008. doi:10.1111/j.1749-6632.2008.03805.x

  • Craik, David J., Rosengren, K. Johan, Sando, Lillian and Simonsen, Shane S. (2006). Threaded rings and complex topologies in antimicrobial peptides: Nature's engineering templates. In: Sylvie E. Blondelle, Understanding biology using peptides: Proceedings of the Nineteenth American Peptide Symposium. 19th American Peptide Symposium, San Diego, CA, United States, (243-247). 18-23 June 2005. doi:10.1007/978-0-387-26575-9_101

  • Rosengren, KJ, Jen, FEC, Clark, RJ, Goransson, U, Daly, NL and Craik, DJ (2005). A novel threaded ring structure for the antimicrobial peptide microcin J25. In: Martin Flegel, Peptides 2004: Bridges between Disciplines ; Proceedings of the Third International and Twenty-Eighth European Peptide Symposium. Peptides 2004: 3rd International Peptide Symposium / 28th European Peptide Symposium, Prague, Czech Republic, (174-175). 5 - 10 September 2004.

  • Craik, D. J., Rosengren, K. J., Clark, R. J., Daly, N. L. and Goransson, U. (2004). A novel threaded ring structure for the antimicrobial peptide microcin J25. In: Oral Presentation Abstracts P91–P118. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, (116-116). 5–10 September 2004. doi:10.1002/psc.617

  • Plan, MR, Goransson, U, Rosengren, KJ, Clark, RJ, Daly, NL, Evert, P, Chen, C, Cagauan, AG and Craik, DJ (2004). Cyclotides: Novel Peptidic Pesticides for Plant Protection. In: Journal of Peptide Science. , , (278-278). .

  • Clark, RJ, Dempster, L, Daly, NL, Rosengren, KJ and Craik, DJ (2004). Design, Synthesis and Structural Studies of Cyclic Alpha-Conotoxins. In: Journal of Peptide Science. , , (269-269). .

  • Craik, David J., Daly, Norelle L., Colgrave, Michelle L. and Rosengren, K. Johan (2004). Discovery and applications of the cyclotides: Circular proteins from plants. In: Peptide Revolution: Genomics, Proteomics & Therapeutics. 18th American Peptide Symposium, Boston, MA, U.S.A., (402-406). 19-23 July 2003.

Grants (Administered at UQ)

PhD and MPhil Supervision

Current Supervision

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Principal Advisor

  • Doctor Philosophy — Principal Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

  • Doctor Philosophy — Associate Advisor

    Other advisors:

Completed Supervision